Patents Assigned to Texas A & M University
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Publication number: 20250060214Abstract: The present disclosure pertains to a circulating tumor cell (CTC) microfluidic platform that is used for the detection of CTCs, enumeration of CTCs in a sample, characterization of biophysical properties, CTC cell size, CTC cell membrane deformability, stresses on CTC cell membranes, adhesion stress on CTC cells, normal stress of CTC cells, or combinations thereof.Type: ApplicationFiled: November 1, 2024Publication date: February 20, 2025Applicant: The Texas A&M University SystemInventors: Jian Sheng, Maryam Jalali-Mousavi
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Patent number: 12230026Abstract: A method for identifying, locating, and mapping targets of interest using unmanned aerial vehicle (UAV) camera footage in GPS-denied environments. In one embodiment, the method comprises obtaining UAV visual data, passing the UAV visual data through a convolutional neural network (CNN) in order to detect targets of interest based on visual features disposed in the UAV visual data, wherein the detection by the CNN defines reference points and pixel coordinates for the UAV visual data, applying a geometric transformation to known and defined pixel coordinates to obtain real-world orthogonal positions; and projecting the detected targets of interest onto an orthogonal map based on the obtained real-world orthogonal positions, all without GPS data.Type: GrantFiled: December 6, 2020Date of Patent: February 18, 2025Assignee: The Texas A&M University SystemInventor: Amir H. Behzadan
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Patent number: 12226031Abstract: A stool includes a base with a post extending therefrom. A seat is connected to a distal end of the post. In some configurations, the seat may be configured to act as a deployable back rest. A deployable anti-fatigue mat is connected to the base. In some configurations, the deployable anti-fatigue mat is attached to the base via a hinged connection. In some configurations, the deployable anti-fatigue mat is attached to the base with a sliding connection that allows the deployable anti-fatigue mat to slide out from the base.Type: GrantFiled: January 20, 2023Date of Patent: February 18, 2025Assignee: The Texas A&M University SystemInventors: Mark E. Benden, Jackson C. Jarman
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Publication number: 20250050353Abstract: In an embodiment, the present disclosure pertains to a droplet system, apparatus, or fluid sample testing system to accomplish high-precision and high-efficiency droplet manipulation (e.g., greater than 99% platform operation efficiency). In some embodiments, the droplet system, apparatus, or fluid sample testing system includes at least one microfluidic channel or chamber and at least one interdigitated electrode (IDE) that can create a localized electric field below and/or within at least one fluidic channel or chamber. In some embodiments, this allows size-specific and/or size-dependent droplet manipulation.Type: ApplicationFiled: December 23, 2022Publication date: February 13, 2025Applicant: The Texas A&M University SystemInventors: Arum Han, Can Huang, Adrian Ryan Guzman, Han Zhang, Jing Dai, Rohit Kunal Gupte
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Patent number: 12220502Abstract: An embodiment includes a system comprising: a substrate of a medical device; an un-foamed polyurethane coating directly contacting the substrate and fixedly attached to the substrate; a thermoset polyurethane shape memory polymer (SMP) foam, having first and second states, which directly contacts the polyurethane coating and fixedly attaches to the polyurethane coating; wherein the polyurethane coating fixedly attaches the SMP foam to the substrate. Other embodiments are described herein.Type: GrantFiled: June 23, 2022Date of Patent: February 11, 2025Assignee: The Texas A&M University SystemInventors: Rachael Muschalek, Keith Hearon, Landon D. Nash, Duncan J. Maitland
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Publication number: 20250043918Abstract: A metal hydride storage system (MHSS) and a method for refueling the MHSS includes obtaining a parameter vector comprising a first state of a metal hydride storage system (MHSS), and a measurable output of the MHSS; sending the parameter vector to a control algorithm, wherein the control algorithm includes a first data structure and a second data structure, wherein the first data structure corresponds to a plurality of critical regions, wherein the second data structure corresponds to a plurality of piecewise affine functions, wherein the affine functions corresponds to a control action; searching the first data structure with the parameter vector; selecting a critical region based on searching the first data structure; selecting, from the second data structure, a piecewise affine function corresponding to the selected critical region; and calculating a control action based on the affine function, where the control action comprises controlling at least one controlled parameter.Type: ApplicationFiled: October 18, 2024Publication date: February 6, 2025Applicant: The Texas A&M University SystemInventors: Gerald S. Ogumerem, Efstratios N. Pistikopoulos
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Publication number: 20250043196Abstract: Disclosed are example efficient circuits that produce spark discharges for hydrocarbon conversion (or treatment of other mixtures) using a high-voltage rectified DC supply to discharge a capacitor (either internal or external) across a two-electrode gap, optimized to minimize waste energy by operating in a constant current, approximately-constant current, or constant power mode. The circuits may operate off of a standard electrical supply line (e.g. 120 VAC or 240 VAC, 60 Hz, single-phase or multi-phase). The disclosed approach is scalable to any number of discharge gaps while maintaining similar pulse characteristics and electrical efficiency.Type: ApplicationFiled: October 14, 2024Publication date: February 6, 2025Applicant: The Texas A&M University SystemInventors: David Staack, Christopher Campbell, Matthew Burnette, Nicholas Gawloski
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Publication number: 20250038768Abstract: A method and system for decoding low density parity check (LDPC) codes. A method includes performing block parallel processing that initiates processing all non-zero block columns of a plurality (M) of rows of a layer of an LDPC matrix in each clock cycle, where M?p, and p is a total number of rows in a layer of the LDPC matrix; and updating a P message responsive to determination of a final state for each row of the LDPC matrix. The LDPC matrix includes layers, each comprising a plurality (M) of rows that are processed per clock cycle. Each of the plurality of rows of each of the layers is datawise independent of the rows processed during a previous NP_MAX clock cycles and at least one row in each layer is datawise dependent on a row of an immediately preceding layer, and NP_MAX is greater than one.Type: ApplicationFiled: October 8, 2024Publication date: January 30, 2025Applicant: The Texas A&M University SystemInventors: Kiran Kumar Gunnam, Gwan S. Choi
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Publication number: 20250032593Abstract: In an embodiment, the present disclosure pertains to a method of reducing cytocidal activity of cells. In some embodiments, the method includes altering eukaryotic elongation factor-2 kinase (eEF-2K) in a subject and inducing a reduction of cytocidal activity of cytotoxic T cells (CTLs) in the subject. In some embodiments, the altering of eEF-2K in the subject can include a decrease of eEF-2K in the subject.Type: ApplicationFiled: December 20, 2022Publication date: January 30, 2025Applicant: The Texas A&M University SystemInventor: Jianxun Jim Song
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Publication number: 20250032010Abstract: In an embodiment, the present disclosure pertains to a wearable sensor. In some embodiments, the wearable sensor includes a double-sided adhesive layer, a paper microfluidic layer, and an encapsulation layer. In an additional embodiment, the present disclosure pertains to a method of biochemical analysis. In general, the method includes collecting biofluid from a subject via a wearable sensor and quantifying the biofluid. In some embodiments, the wearable sensor includes a double-sided adhesive layer and a paper microfluidic layer having a microfluidic channel in a serpentine configuration. In some embodiments the microfluidic channel includes an inlet to receive the biofluid, an outlet to collect the excess biofluid, and a plurality of plasmonic sensors.Type: ApplicationFiled: December 6, 2022Publication date: January 30, 2025Applicant: The Texas A&M University SystemInventors: Limei Tian, Umesha Mogera, Heng Guo
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Patent number: 12208377Abstract: A solution consisting of: a poly(a-olefin) (PAO) selected from the group consisting of PAO283, PAO432, and PAO687; and a reactive organometallic reagent selected from the group consisting of n-butyllithium, sec-butyllithium, tert-butyllithium, n-butyllithium in hexane, sec-butyllithium in cyclohexane, and tert-butyllithium in pentane.Type: GrantFiled: July 30, 2019Date of Patent: January 28, 2025Assignee: The Texas A&M University SystemInventors: David E. Bergbreiter, Thomas J. Malinski
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Patent number: 12209159Abstract: An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.Type: GrantFiled: March 24, 2023Date of Patent: January 28, 2025Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University SystemInventors: Keith Hearon, Landon D. Nash, Thomas Wilson, Duncan J. Maitland, Mark A. Wierzbicki
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Publication number: 20250030824Abstract: A method for reconstructing a three-dimensional (3D) of a sample includes displacing an outer surface of the sample at a desired sample, repeatedly activating an ultraviolet stroboscopic illuminator to produce ultraviolet excitation light at a frequency that is based on the speed of the sample, repeatedly activating a pair of laterally spaced cameras of a stereoscopic imaging unit as the outer surface of the sample is displaced to capture a plurality of 2D images of different sections of the outer surface of the sample, and reconstructing a 3D image of the sample from the plurality of 2D images of the different sections captured by the pair of cameras.Type: ApplicationFiled: October 4, 2024Publication date: January 23, 2025Applicant: The Texas A&M University SystemInventor: ChaBum Lee
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Patent number: 12203068Abstract: In an embodiment, a strand displacement system including a DNA/PNA complex, an input DNA strand, where the DNA/PNA complex binds to the input DNA strand forming a complex and displaces a PNA intermediate and forms an activated domain on the PNA, and a Bi complex that reacts with the activated domain on the PNA to thereby release an output DNA strand. In an additional embodiment, a fluorogenic sensor including a heteroduplex between an achiral PNA strand and a fluorogenic aptamer, where the fluorogenic aptamer includes L-RNA, an input DNA strand, where the input DNA strand binds to the heteroduplex and displaces an incumbent fluorogenic aptamer strand and forms an activated domain on that strand, and a dye.Type: GrantFiled: February 4, 2019Date of Patent: January 21, 2025Assignee: The Texas A&M University SystemInventors: Jonathan T. Sczepanski, Adam M. Kabza, Brian E. Young
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Publication number: 20250018613Abstract: In an embodiment, the present disclosure pertains to a method of recycling that includes applying an electromagnetic field to a composite material having carbon fiber therein, heating the composition, degrading a matrix of the composite material, and recovering the carbon fiber from the composite material. In an additional embodiment, the present disclosure pertains to a method of non-contact recycling that includes applying an electromagnetic field to a composite material having carbon fiber therein with an electromagnetic applicator via at least one of direct current or alternating current, heating the composition, degrading a matrix of the composite material, and recovering the carbon fiber from the composite material. In some embodiments, the electromagnetic field is applied in a non-contact manner.Type: ApplicationFiled: November 17, 2022Publication date: January 16, 2025Applicants: The Texas A&M University System, Texas Research Institute Austin, Inc.Inventors: Micah J. Green, Mohammad G. Naraghi, Aniruddh Vashisth, Spencer Hawkins
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Publication number: 20250019598Abstract: A high voltage discharge generating a plasma wave front is disposed within a headspace over an oil-containing liquid in order to create various chemical changes within the headspace, and ultimately within the liquid in order to inactivate various microbes, synthesize new chemicals, speed separation of a mixture, and aid in oil extraction. Such a discharge may be repeated at an optimum duration and duty-cycle to maximize the chemical effects of the non-equilibrium plasma at a substantially lower temperature than for an equilibrium plasma.Type: ApplicationFiled: September 30, 2024Publication date: January 16, 2025Applicant: The Texas A&M University SystemInventors: Jamie Kraus, David Staack, Howard Jemison
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Patent number: 12193887Abstract: An apparatus for surgical lighting is disclosed. The apparatus includes a light emitting element formed with a light source encapsulated within an outer layer. The outer layer includes a biocompatible material. A power supply is coupled to the light source. The apparatus includes an actuating mechanism that controls power from the power supply to the light source to emit light along a surgical area. The light emitting element provides enhanced illumination and other surgical advantages.Type: GrantFiled: April 13, 2023Date of Patent: January 14, 2025Assignees: Dignity Health, The Texas A&M University SystemInventors: Clinton Morgan, Peter Nakaji, Sung Il Park
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Patent number: 12193689Abstract: An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.Type: GrantFiled: August 5, 2022Date of Patent: January 14, 2025Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University SystemInventors: Jason Szafron, Duncan Maitland, Ward Small, IV, Patrick R. Buckley, Andrea D. Muschenborn
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Patent number: 12196618Abstract: A passive infrared (PIR) sensor system, includes a PIR sensor configured to produce an output signal in response to receiving infrared (IR) radiation, an electronic shutter positionable in a field of view (FOV) of the PIR sensor, wherein the electronic shutter includes a liquid crystal (LC) material, wherein the electronic shutter includes a first state providing a first transmissivity of IR radiation through the electronic shutter and a second state providing a second transmissivity of IR radiation through the electronic shutter that is less than the first transmissivity, and a shutter actuator configured to apply an actuation signal to the electronic shutter to actuate the electronic shutter between the first state and the second state.Type: GrantFiled: June 19, 2020Date of Patent: January 14, 2025Assignee: The Texas A&M University SystemInventors: Ya Wang, Libo Wu, Zhangjie Chen
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Publication number: 20250012609Abstract: In an embodiment, a method for measuring parameters of a liquid, where the method includes measuring pressure drops across a flow meter, measuring pressure upstream of the flow meter, and identifying at least one liquid parameter based, at least in part, on a correlation of a change in a multiphase flow parameter to pulse output. In an additional embodiment, a measuring apparatus for measuring parameters of a liquid, where the measuring apparatus includes an electronic control operable to measure pressure drops across the measuring apparatus, measure pressure upstream of the measuring apparatus, and correlate a change in a multiphase parameter to measured pulse output of the measuring apparatus.Type: ApplicationFiled: July 29, 2024Publication date: January 9, 2025Applicant: The Texas A&M University SystemInventors: Abhay R. Patil, Gerald Morrison, Joshua A. Vandervort