Abstract: Gracilin A congeners and methods for their use as immunosuppressive and neuroprotective agents.

Abstract: Methods and reactors for electrochemically expanding a parent material and expanded parent materials are described. Current methods of expanding parent materials incompletely-expand parent material, requiring expensive and time-consuming separation of expanded parent material from unexpanded parent materials. This problem is addressed by the methods and reactor for electrochemically expanding a parent material described herein, which during operation maintain electrical connectivity between the parent material and an electrical power source. The resulting materials described herein have a greater proportion of expanded parent material relative to unexpanded parent material compared to those made according to others methods.

Abstract: Various embodiments are disclosed for a machine learning system for automatic genotype selection and performance evaluation using multi-source and spatiotemporal remote sensing data collected from an unmanned aerial system (UAS). A computing device may be configured to access images of a field having a first genotype and a second genotype of at least one crop or plant planted therein. The computing device may apply an image processing routine to the images to analyze the images of the field and determine characteristics of the first genotype and the second genotype of the at least one crop or plant planted in the field. The computing device may then apply a machine learning routine to forecast a first estimated yield of the first genotype and a second estimated yield of the second genotype using the identified characteristics of the first genotype and the second genotype.

Abstract: The present invention discloses crystal structure of Staphylococcus aureus Clumping factor A (ClfA) in complex with fibrinogen (Fg) derived peptide. Also, the present invention also discloses the use of this structure in the design of ClfA targeted vaccines and therapeutic agents (including monoclonal antibodies). In addition, the present invention discloses isolated and purified engineered Staphylococcus clumping factor A protein (ClfA) with a stabilized, closed conformation and immunogenic compositions thereof including methods of treating a Staphylococcus infection in an individual.

Abstract: Systems and related methods are disclosed for characterizing physical phenomena. In an embodiment, the system includes a frame defining an active volume, a camera configured to capture an image of the active volume, and a controller coupled to the camera. In an embodiment, the controller is configured to: track an object within the active volume via the camera, analyze a motion of the object within the active volume, and output a visual depiction of the object and one or more vectors characterizing the motion of the object on a display.

Abstract: An energy storage device and method of forming and operating the same. In one embodiment, the energy storage device includes a positive electrode including a first redox polymer deposited on a first conductive porous substrate. The energy storage device also includes a solid-state polyelectrolyte separator operative as a voltage generator, and a negative electrode including a second redox polymer deposited on a second conductive porous substrate, thereby forming an electrochemical cell.

Abstract: In an embodiment, a composition including a chiral solvating agent to resolve nuclear magnetic resonance signals of an enantiomer of at least one analyte, where the chiral solvating agent facilitates in the at least one analyte binding to a C2 face or a C3 face of the chiral solvating agent, and where the chiral solvating agent causes an upfield shift or a downfield shift in at least one nuclear magnetic resonance signals corresponding to a 1H, 19F{1H}, or 31P{1H} signal, and where the chiral solvating agent includes a cobalt cation. In another embodiment, a method that includes mixing a chiral solvating agent, including a cobalt cation, with at least one analyte to form a solution, obtaining nuclear magnetic resonance spectra of the solution, and identifying an enantiomer of the at least one analyte. In some embodiments, the method further includes determining enantiomeric purities of the at least one analyte.

Abstract: A desk includes a tabletop and at least one base member supporting the tabletop. A footrest is disposed on the at least one base member beneath the tabletop. The footrest is movable between a stowed position toward a back of the desk and a deployed position toward a front of the desk. At least one mechanism is disposed on the at least one base member and operatively coupled to the footrest. The at least one mechanism moving the footrest between the stowed and deployed positions. A floor mat is disposed with the footrest. The floor mat is movable with the footrest between a stowed mat position and a deployed mat position.

Abstract: A power converter includes a multiple-winding transformer. The multiple-winding transformer provides an electromagnetic link between an input side and an output side of the power converter. An inductor is arranged on at least one of the input side and the output side of the power converter in parallel with the multiple-winding transformer. At least one first capacitor is arranged on the input side of the power converter in parallel with the multiple-winding transformer and the inductor. At least one second capacitor is arranged on the output side of the power converter in parallel with the multiple-winding transformer. The inductor, the at least one first capacitor, and the at least one second capacitor define a parallel resonance tank. A first plurality of switching devices is arranged on the input side. A second plurality of switching devices is arranged on the output side.

Abstract: Methods for reducing the concentration of one or more contaminants in water using zero-valent iron media. In the method, a mixed aluminum (III) and iron (II) salt solution is added to water containing one or more contaminants that is in contact with a zero-valent iron media that comprises (a) a reactive solid comprising zero-valent iron and one or more iron oxide minerals in contact therewith and (b) magnetite to provide an aqueous reaction medium. The aqueous reaction medium is contacted with the zero-valent iron media for a period of time sufficient to reduce the concentration of one or more of the contaminants.

Abstract: Computer-aided methods for performing computations using adversarially-robust neural networks is disclosed that includes providing a uncoded neural network comprising a plurality of neurons and associated inputs for each of the plurality of neurons, each neuron configured to perform a calculation according to an activation function. The method further includes transforming, using the computing device, at least one uncoded neuron into a coded neuron by adding, using the computing device, an error correcting code as an additional input to the at least one uncoded neuron, the error correcting code comprising a redundant combination of the associated inputs off the uncoded neuron, and revising, using the computing device, the activation function of the at least one uncoded neuron to accommodate the error correcting code as the additional input.

Abstract: Embodiments concern coupling polarized light at two or more wavelengths across the aqueous humor of the eye (e.g., as part of a noninvasive glucose monitoring system). An approach discloses non-contact and minimal contact eye-coupling designs that are part of a system for providing glucose concentration levels via measurements acquired by passing two or more optical beams through the cornea/aqueous chamber in the eye. The approach provides for coupling the light to account for the index mismatch incurred while allowing for monitoring the light polarization. Specifically, in an embodiment the light transitions from the device, through the air, through the proximal side of the cornea, through the aqueous humor, through the medial side of the cornea, and through the air back into the device. Embodiments address the index of refraction mismatch and polarized light maintaining concerns with a coupling approach that can take the form of contact and non-contact mechanisms.

Abstract: A method of forming polymer composites includes mixing a transition metal oxide precursor including at least one transition metal, a polymer as a binder, a solvent for the polymer, and water to form a first solution including polymer-transition metal complexes. The polymer-transition metal complexes are hydrolyzed to produce a plurality of transition metal oxide nanoparticles, wherein water is added in the mixing in a stoichiometric excess for the hydrolyzing. The solvent and residual of the water remaining after the hydrolyzing are removed. A polymer composite including the transition metal oxide nanoparticles dispersed in the polymer results after the removing, where some of the polymer is chemically conjugated to a surface of the transition metal oxide nanoparticles.

Abstract: A vaccine includes at least one bacterial antigen capable of producing an immune response in a host when the vaccine is administered at a dose that is sufficient for preventing or treating Q fever in the host. The vaccine composition confers immunity against Q fever without the reactogenic side effects observed in prior art vaccines.

Abstract: Provided herein are fiber reinforced cementitious materials and mixtures with increased crack resistance. The cementitious materials and mixtures include a cement and at least one carbon fiber. Also provide is a fiber reinforced cementitious mortar that includes the fiber reinforced cementitious material to which at least one of water, an aggregate material or a chemical admixture is added.

Abstract: Nanodiamonds are grown under conditions where diamond-like organic seed molecules do not decompose. This permits engineered growth of fluorescent nanodiamonds wherein a custom designed seed molecule can be incorporated at the center of a nanodiamond. By substituting atoms at particular locations in the seed molecule it is possible to achieve complex multi-atom diamond color centers or even to engineer complete quantum registers. In addition, it is possible to grow ultra-small nanodiamonds, wherein each nanodiamond, no matter how small, can have at least one bright and photostable fluorescent emitter.

Abstract: The present disclosure provides methods, reagents, systems, and devices that target ? lactamase as a biomarker for the sensitive and specific detection of tuberculosis-complex bacteria. Specifically, the present disclosure relates to methods and compositions for the detection of specific ?-lactamase protein and nucleic acid sequences to indicate the presence of tuberculosis-complex bacteria.

Abstract: A system for enhancing overall energy production of CSPs through amplification of solar heat collection. In one embodiment, the system comprises a linear solar-thermal concentrator for concentrating solar light comprising a curved surface, two side walls, and an opening; a fluid conduit disposed within the linear solar-thermal concentrator that carries a working fluid through the linear solar-thermal concentrator; and a convection cover disposed over the opening of the linear thermal concentrator that traps heat convection energy within the linear solar-thermal concentrator.

Abstract: Provided herein are drilling muds, including water-based drilling muds. The components of the drilling muds are a degradable fluid loss additive, for example, synthetic degradable nanoparticles, a clay mineral, for example, a smectite, and a base fluid, for example, water. Also provide are methods for preventing leak-off during a drilling operation and for automatically cleaning-up filter cake after completion of a drilling process both of which utilize the drilling muds and water-based drilling muds.

Abstract: Embodiments of the invention are directed to Ubx-fusion molecules that maintain their mechanical strength and properties even after being fused with Ubx. Ubx fusions with VEGF and other growth factors, cell signaling proteins, and cell binding proteins can be used to induce angiogenesis. Ubx fibers and mesh, embedded within a tissue engineering scaffold, induce formation of vasculature within the scaffold. The presence of vasculature is necessary to provide oxygen and nutrients to other cells growing within the scaffold.