Patents Assigned to The Board of Regents for Oklahoma State University
  • Publication number: 20080076716
    Abstract: An antimicrobial peptide and its analogs that are insensitive to physiological salt and divalent cation concentrations is provided, as are methods for their use to treat and prevent bacterial infections. The peptides are especially useful to treat infections caused by bacteria that are resistant to traditional antibiotic therapy.
    Type: Application
    Filed: September 18, 2007
    Publication date: March 27, 2008
    Applicant: The Board of Regents for Oklahoma State University
    Inventors: Guolong Zhang, Amar Patil
  • Patent number: 7252576
    Abstract: A method of polishing workpieces in a magnetic float polishing chamber comprising a lower chamber piece and an upper chamber piece which is removably receivable in the lower chamber piece and is connected to a powered spindle for rotating the upper chamber piece in the polishing operation. The method preferably comprises one or more of the steps of (a) geometrically aligning the upper chamber piece with the powered spindle by machining the upper chamber piece in-situ, (b) machining the contact surface of the upper chamber piece in-situ between various polishing runs, and (c) mounting the lower chamber piece in a manner effective for causing the lower piece to automatically self-align coaxially with the upper chamber piece.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: August 7, 2007
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Ranga Komanduri, Tejas Shrikant Kirtane, Robert Edward Gerlick, Noritsugu Umehara, Vijay Kumar Jain
  • Patent number: 7244435
    Abstract: The invention is for a DNA vaccine expressing the hemagglutinin (HA1) gene of equine-2 influenza virus. By engineering a stop codon within HA1, expression of HA1 is ensured. By encapsulation of the DNA vaccine in liposome and by intranasal inoculation, it is sufficient to elicit protective immunity at a significantly lower dosage compared to a DNA vaccine expressing the full length HA gene. Lower dosage reduces the risk of induction of anti-DNA antibodies. Intranasal inoculation directly to the respiratory epithelial cells reduces the risk of DNA integration. The inventive vaccine is advantageous over current inactivated or live attenuated vaccines, as updating of the vaccine requires only the replacement of the encoding sequence with the new virus.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: July 17, 2007
    Assignee: Board of Regents for Oklahoma State University
    Inventor: Alexander Lai
  • Patent number: 7214784
    Abstract: Protective antigens against infestations with Ixodes spp. ticks, gene sequences and encoded proteins for such antigens, related vaccines and methods useful to induce an immune response, which are protective to interfere with infestations by Ixodes spp. ticks are presented.
    Type: Grant
    Filed: April 29, 2003
    Date of Patent: May 8, 2007
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Jose de Jesús de la Fuente, Katherine M. Kocan, Consuelo García-Almazán, Jose Carlos García-García, Edmour F. Blouin
  • Patent number: 7208898
    Abstract: Method and apparatus for control object manipulation from an initial position to a final position. A jerk control profile describes a near time-optimal jerk trajectory for the control object and includes a sequence of first, second and third sinusoidal pulses of respectively alternating polarity and common absolute magnitude. The area of the second pulse is nominally equal to the combined area of the first and third pulses, and the pulses are preferably symmetric about the respective maximum pulse values. Associated control profiles (control voltage, current, velocity, displacement, etc.) are derived from the jerk control profile. For longer seeks, constant, non-zero jerk segments are inserted into the profile between the pulses, during which control voltage is maintained near saturation. The control object preferably comprises a transducer in a data storage device and the jerk control profile is stored in a memory location of the device.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: April 24, 2007
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Chad Andrew Stoecker, Eduardo Akira Misawa, Clyde Everett Goodner, III
  • Patent number: 7201066
    Abstract: An apparatus and method for measuring gas flow rates and an improved automatic vehicle tire inflation system which utilizes the inventive gas flow measurement apparatus and method. The gas flow measuring apparatus and method utilize a porous media material effective for creating an appropriate pressure differential relative to the gas flow rate.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: April 10, 2007
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Marvin Lyle Stone, John Bruce Solie
  • Publication number: 20070071738
    Abstract: A ruminant direct fed microbial composition of matter comprising an acidosis inhibiting effective amount of Propionibacterium P-63 is provided. Also disclosed is a process for reducing acidosis in ruminants or scours in swine by administration of the bacterium to the ruminant or swine. The microbial composition may be administered by itself, or combined with animal feed and/or lactic acid producing cultures.
    Type: Application
    Filed: November 29, 2006
    Publication date: March 29, 2007
    Applicant: The Board of Regents for Oklahoma State University
    Inventors: Thomas Rehberger, Terry Parrott, Fred Owens, Charles Hibberd
  • Patent number: 7188450
    Abstract: A method for in-season macro and micronutrient application based on predicted yield potential, coefficient of variation, and a nutrient response index. The inventive method includes the steps of: determining a nutrient response index for a field; determining the normalized difference vegetation index (NDVI) of an area to fertilize; determining the coefficient of variation of NDVI over a plot; determining a predicted crop yield for the area without additional nutrient; determining an attainable crop yield for the area with additional nutrient; determining the nutrient requirement for the area as the difference between the nutrient removal at the attainable yield minus the nutrient removal at the predicted yield, adjusted by the efficiency of nutrient utilization in the particular crop as indicated by the coefficient of variation.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: March 13, 2007
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: William R. Raun, Gordon V. Johnson, John B. Solie, Marvin L. Stone, Kyle Freeman
  • Patent number: 7144580
    Abstract: Vaccines and methods against M. haemolytica infections in cattle. The vaccine compositions include a recombinant outer membrane protein of M. haemolytica designated PlpE and/or subunits thereof, alone or in combination with other antigenic components, and a carrier or diluent. The methods involve administering an effective immunizing amount of the vaccines to susceptible bovine.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: December 5, 2006
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Anthony W. Confer, Sahlu Ayalew, George L. Murphy, Karamjeet Pandher
  • Patent number: 7045087
    Abstract: A method for the layer-by-layer assembly of a free standing thin film includes the steps of preparing a support with a suitable substrate; forming a thin film having a plurality of layers onto the substrate utilizing a layer-by-layer assembly process; removing the substrate and thin film from the support; and separating the substrate from the thin film. Various compounds improving the strength, flexibility, tension and other mechanical properties may be included in the assembly to improve the structural quality of the film. Similar effect may also be achieved by cross-linking the applied layers.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: May 16, 2006
    Assignee: The Board of Regents for Oklahoma State University
    Inventor: Nicholas A. Kotov
  • Patent number: 7002163
    Abstract: There is provided herein a system and method for obtaining measurements of radiation exposure in real time using OSL and for obtaining improved accurate OSL measurements over a greater range of radiation exposures. In a preferred embodiment a signal-versus-dose response is obtained from an OSL dosimeter that is linear over all doses and does not exhibit saturation effects. The desired response is preferably calculated from the measured OSL-versus-time response from a suitable dosimeter obtained during irradiation. To obtain the desired response from the measured OSL data each measured OSL point has to be corrected for the depletion of the trapped electron concentration that occurs during each illumination period.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: February 21, 2006
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Jerimy C. Polf, Razvan Gaza, Stephen W. S. McKeever
  • Patent number: 6979451
    Abstract: Vaccines and methods for inducing an immune response in a ruminant. The vaccine composition including pathogen and tick-derived antigens and a carrier or diluent. The method for inducing an immune response in a ruminate to provide immune protection which reduces the infection of ticks by A. marginale and/or prevents the transmission of the pathogen includes the steps of administering to the ruminant an effective amount of the vaccine composition having at least one antigen member of the group comprising at least one antigen member of the group comprising (i) recombinant MSP1a surface protein antigen of A. marginale, (ii) a subunit of recombinant MSP1a surface protein antigen of A. marginale and (iii) recombinant MSP1a surface protein antigen or subunits thereof in combination with antigen preparation derived from A. marginale infected cultured tick IDE8 cells and/or other pathogen and tick-derived antigens, and a carrier or diluent.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: December 27, 2005
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Jose de Jesus de la Fuente, Katherine M. Kocan, Jose Carlos Garcia-Garcia, Edmour F. Blouin
  • Patent number: 6939549
    Abstract: Vaccines and methods useful to induce an immune response which is protective to reduce the severity or prevent infection by ehrlichial parasites of the species Anaplasma marginale utilizing recombinant MSP1a surface protein antigens alone or in combination with tick cell culture derived A. marginale.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: September 6, 2005
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Jose de Jesus de la Fuente, Katherine M. Kocan, Jose Carlos Garcia-Garcia, Edmour F. Blouin
  • Patent number: 6936830
    Abstract: There is provided a system and method for estimating radiation exposure in real time or in near-real time while a dosimeter is being irradiated. In the preferred arrangement, OSL will be used to calculate estimates of the radiation dose rate, preferably by using comparisons between illumination values measured during and after lighting the dosimeter with a laser light of a predetermined frequency. A first preferred embodiment utilizes quasi-equilibrium OSL intensity with periodic stimulation during continuous irradiation. Another preferred embodiment utilizes the amplitude of the transient OSL signal during periodic stimulation. Another preferred embodiment utilizes the difference between the OSL intensity at the end of one stimulation period and the beginning of the next. Finally, another preferred monitors the time constant for the return of the transient OSL signal to equilibrium, following either a change in dose rate or during a periodic optical stimulation.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: August 30, 2005
    Assignees: The Board of Regents for Oklahoma State University, Landauer, Inc.
    Inventors: Razvan Gaza, Mark S. Akselrod, Stephen W. S. McKeever
  • Patent number: 6887489
    Abstract: A ruminant direct fed microbial composition of matter comprising an acidosis inhibiting effective amount of Propionibacterium P-63 is provided. Also disclosed is a process for reducing acidosis in ruminants or scours in swine by administration of the bacterium to the ruminant or swine. The microbial composition may be administered by itself, or combined with animal feed and/or lactic acid producing cultures.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: May 3, 2005
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Thomas Rehberger, Terry D. Parrott, Fred C. Owens, Charles A. Hibberd
  • Patent number: 6880291
    Abstract: A method for in-season macro and micronutrient application based on predicted yield potential and a nutrient response index. The inventive method includes the steps of: determining a nutrient response index for a field; determining the normalized difference vegetation index (NDVI) of an area to fertilize; determining a predicted crop yield for the area; determining an attainable crop yield for the area; determining the nutrient requirement for the area as the difference between the nutrient removal at the attainable yield minus the nutrient removal at the predicted yield, adjusted by the efficiency of nutrient uptake in the particular crop. In one preferred embodiment, processing requirements at the time of application of the nutrient are eased by generating a lookup table of nutrient requirement relative to measured NDVI prior to application of the nutrient.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: April 19, 2005
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: William R. Raun, Gordon V. Johnson, John B. Solie, Marvin L. Stone
  • Patent number: 6855933
    Abstract: A spectral reflectance sensor including: a light source for emitting a modulated beam of red light; a light source for emitting a modulated beam of near infrared light; a receiver for receiving reflected light produced by either the red source or the near infrared source; a receiver for receiving incident light from either the red source or the infrared source; a signal conditioner responsive to the modulation such that the signals produced by the receivers in response to reflected and incident light from the source can be discriminated from signals produced by ambient light; and a microprocessor having an input such that the microprocessor can determine the intensities of incident red light, reflected red light; incident near infrared light; and reflected near infrared light. From these intensities, and by knowing the growing days since emergence or planting, the sensor can calculate the mid-growing season nitrogen fertilizer requirements of a plant.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: February 15, 2005
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Marvin L. Stone, Duane Needham, John B. Solie, William R. Raun, Gordon V. Johnson
  • Publication number: 20040262538
    Abstract: There is provided herein a system and method for obtaining measurements of radiation exposure in real time using OSL and for obtaining improved accurate OSL measurements over a greater range of radiation exposures. In a preferred embodiment a signal-versus-dose response is obtained from an OSL dosimeter that is linear over all doses and does not exhibit saturation effects. The desired response is preferably calculated from the measured OSL-versus-time response from a suitable dosimeter obtained during irradiation. To obtain the desired response from the measured OSL data each measured OSL point has to be corrected for the depletion of the trapped electron concentration that occurs during each illumination period.
    Type: Application
    Filed: May 24, 2004
    Publication date: December 30, 2004
    Applicant: The Board of Regents for Oklahoma State University
    Inventors: Jerimy C. Polf, Razvan Gaza, Stephen W.S. McKeever
  • Publication number: 20040231239
    Abstract: A method for in-season macro and micronutrient application based on predicted yield potential, coefficient of variation, and a nutrient response index. The inventive method includes the steps of: determining a nutrient response index for a field; determining the normalized difference vegetation index (NDVI) of an area to fertilize; determining the coefficient of variation of NDVI over a plot; determining a predicted crop yield for the area without additional nutrient; determining an attainable crop yield for the area with additional nutrient; determining the nutrient requirement for the area as the difference between the nutrient removal at the attainable yield minus the nutrient removal at the predicted yield, adjusted by the efficiency of nutrient utilization in the particular crop as indicated by the coefficient of variation.
    Type: Application
    Filed: March 16, 2004
    Publication date: November 25, 2004
    Applicant: The Board of Regents for Oklahoma State University
    Inventors: William R. Raun, Gordon V. Johnson, John B. Solie, Marvin L. Stone, Kyle Freeman
  • Patent number: PP16801
    Abstract: ‘Patriot’ is an improved clonal turf bermudagrass cultivar suitable for many applications including golf course fairways and tees athletic fields, home and commercial landscape sites, and parks and playgrounds. It is a tetraploid (2n=4x=36 chromosomes) interspecific F1 hybrid from a cross of Cynodon dactylon by C. transvaalensis characterized by dark blue-green color, vigorous growth, good winter hardiness, and good turf quality.
    Type: Grant
    Filed: June 22, 2004
    Date of Patent: July 11, 2006
    Assignee: The Board of Regents for Oklahoma State University
    Inventors: Charles M. Taliaferro, Dennis L. Martin, Jeffrey A. Anderson, Michael P. Anderson