Patents Assigned to The Board of Regents of the University of Oklahoma
  • Patent number: 10377941
    Abstract: Stable CNT dispersions having a combination of polymeric dispersants, including at least one first dispersant and at least one second dispersant, wherein the second dispersant is stable under saline conditions, and methods of using the CNT dispersions in subterranean formations for enhancing oil recovery therefrom.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: August 13, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Mohannad J. Kadhum, Daniel E. Resasco, Jeffrey H. Harwell, Ben Shiau, Daniel P. Swatske
  • Patent number: 10359379
    Abstract: A method of using NMR to estimate pore connectivity in a shale formation by estimating organic pore connectivity in a first sample of the shale formation and inorganic pore connectivity in a second sample of the shale formation based on uptake of brine and hydrocarbon phases. Porosity partitioning of the shale formation may be estimated with a third sample of the shale formation.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: July 23, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Ali Ousseini Tinni, Carl Sondergeld, Chandra Rai
  • Publication number: 20190218603
    Abstract: Primer and/or probe sets and arrays for determining microRNA (miRNA) expression signatures that are specific to doublecortin-like kinase 1 (DCLK1) activity, and methods of their use, are disclosed.
    Type: Application
    Filed: May 18, 2017
    Publication date: July 18, 2019
    Applicant: The Board of Regents of the University of Oklahoma
    Inventors: Courtney W. HOUCHEN, Nathaniel WEYGANT, Dongfeng QU, Randal MAY, Parthasarathy CHANDRAKESAN
  • Patent number: 10330663
    Abstract: System and method relates to measuring separation rate of water from water-in-crude oil emulsions at elevated temperature. The system includes an electrolytic interface (conductivity) cell comprising a plurality of capacitance/conductance probes disposed at different heights in a fluid stream disposed within the interface cell and an analyzer. Logic of the analyzer determines the separation rate based on signals received from the plurality of capacitance/conductance probes in the interface cell that are coupled to monitor the fluid stream. Methods for making and using the system are also disclosed.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: June 25, 2019
    Assignees: PHILLIPS 66 COMPANY, BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
    Inventors: Moniraj Ghosh, Brian P. Grady, Jeffrey H. Harwell, James A. Miles
  • Patent number: 10329518
    Abstract: Monomeric and oligomeric compounds of Formula (I) comprising hydrophobic alkyl or alkenyl ester moieties and hydrophilic carboxylate moieties: wherein R1 is C1-C6 alkyl, R2 is Cl0-C30 alkyl or C8-C30 alkenyl, Y is a cation, Z is a sulfur-containing moiety, and n and k are integers as defined herein. The compounds of Formula (I) have surfactant properties. Also provided are compositions comprising the compounds of Formula (I), and methods of using the compounds or compositions for cleaning purposes.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: June 25, 2019
    Assignees: Board of Regents of the University of Oklahoma, Novus International, Inc.
    Inventors: Graciela B. Arhancet, Scott A. Long, Brian Grady, Jeff Harwell, Guangzhe Yu
  • Patent number: 10283658
    Abstract: Photovoltaic (PV) and photodetector (PD) devices, comprising a plurality of interband cascade (IC) stages, wherein the IC stages comprise an absorption region with a type-I superlattice and/or a bulk semiconductor material having a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: May 7, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Rui Q. Yang
  • Patent number: 10279180
    Abstract: A method of treating heart failure in a patient is disclosed that includes implanting a stimulation device into the identified patient to electrically stimulate the spinal cord, and activating the device to deliver electrical stimulation to the spinal cord.
    Type: Grant
    Filed: April 17, 2017
    Date of Patent: May 7, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Robert D. Foreman, Jeffrey L. Ardell, John A. Armour, Michael J. L. DeJongste, Bengt G. S. Linderoth
  • Patent number: 10273517
    Abstract: Testosteronan, a heparosan analog having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n, is produced by testosteronan synthase, a single protein that is a dual-action catalyst that utilizes UDP-GlcUA and UDP-GlcNAc to synthesize a polysaccharide having the structure [-4-D-GlcUA-?1,4-D-GlcNAc-?1-]n.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: April 30, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Nigel J. Otto
  • Patent number: 10258613
    Abstract: Compositions for use in methods of treating and/or inhibiting a pathologic ocular condition, as well as methods of producing and using same, are disclosed.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: April 16, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Xi-Qin Ding, Hongwei Ma
  • Patent number: 10226523
    Abstract: Embodiments of the present disclosure include vaccine compositions comprising a TcdB toxin or toxoid derived therefrom. The TcdB toxin may be derived from a hypervirulent strain of C. difficile. A further embodiment is directed to a method of conferring an active immunity against a C. difficile infection in a subject by administering the vaccine composition to the subject.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: March 12, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Jordi M. Lanis, Jimmy D. Ballard
  • Patent number: 10228376
    Abstract: The present invention provides a panel of at least five clinical analyses or tests (using serum samples) to determine the risk of pediatric acute-onset neuropsychiatric syndrome (PANS) and/or pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection (PANDAS) in an individual. These include enzyme linked immunosorbent assays (ELISAs) to measure antibody titers against neuronal antigens present in the brain; the neuronal antigens include lysoganglioside, tubulin, dopamine receptor D1, dopamine receptor D2, serotonin receptor 5HT2A, and serotonin receptor 5HT2C. Antibody titers against at least four of these neuronal antigens are required in the present methods; preferably antibody tiers against all of these neuronal antigens are measured. A final assay is used to quantify calcium/calmodulin-dependent protein kinase activity using a neuronal cell line.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: March 12, 2019
    Assignees: Moleculera Labs, Inc., The Board of Regents of the University of Oklahoma, The United States of America, As Represented by the Secretary, Department of Health and Human Serv
    Inventors: Phina Madeleine Cunningham, Craig David Shimasaki, Susan E. Swedo, Christine Kirvan
  • Patent number: 10206904
    Abstract: Derivatives of licofelone for the treatment of chronic inflammatory diseases and epithelial cancers associated with chronic inflammation are disclosed. The agents target mPGES-1 and 5-LOX.
    Type: Grant
    Filed: July 13, 2016
    Date of Patent: February 19, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Chinthalapally V. Rao, Naveena B. Janakiram, Hariprasad Gali, Altaf Mohammed, Gopal Pathuri
  • Publication number: 20190048287
    Abstract: The present invention relates to microemulsions and methods of preparing and using the microemulsions.
    Type: Application
    Filed: August 11, 2017
    Publication date: February 14, 2019
    Applicant: Board of Regents of the University of Oklahoma
    Inventors: Scott Long, Graciela Arhancet, Brian Grady, Jeff Harwell, Guangzhe Yu
  • Patent number: 10174077
    Abstract: The presently disclosed inventive concept(s) include inhibitors of antiplasmin cleaving enzyme (APCE) and fibroblast activation protein alpha (FAP) which can be used in various therapies related to disorders of fibrin and ?2-antiplasmin and abnormal cell proliferation. The presently disclosed inventive concept(s) also include substrates of APCE and FAP, which may be used, for example, in screening methods for identifying such inhibitors. The presently disclosed inventive concept(s) further include, but are not limited to, methods of treating or inhibiting atherosclerosis and thrombus disorders by altering the ratios of types of plasma ?2-antiplasmin and to methods of treating conditions involving abnormal cell proliferation such as cancers.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: January 8, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Patrick A. McKee, Kenneth W. Jackson, Kyung N. Lee, Victoria J. Christiansen
  • Patent number: 10166386
    Abstract: An electrode assembly includes a retainer, a flexible sheath, and an electrode. The retainer may include a plurality of clasping arms. The retainer is movable to an open position and a closed position. The flexible sheath is positioned below a lower surface of the retainer. The flexible sheath is at least partially surrounded by the clasping arms of the retainer. The retainer is able to hold the flexible sheath around a target tissue when the retainer is in the closed position. The electrode is configured for conducting electrical signals to or from the target tissue. The electrode is connected to at least one of the retainer and the flexible sheath. The retainer is able to hold the electrode in electrical communication with the target tissue when the retainer is disposed around the target tissue in the closed position.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: January 1, 2019
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Nilesh Raman Vasan
  • Patent number: 10155789
    Abstract: Inhibitors of fibroblast activation protein alpha (FAP) and Prolyl Oligopeptidase (POP) are disclosed, along with their use in various therapies related to conditions, diseases, and disorders involving abnormal cell proliferation such as malignancies and angiogenesis, and in neural disorders such as Alzheimer's disease. Stalk portions of the inhibitor molecules, and substrates of FAP and POP, are also disclosed and may be used, for example, in screening methods for identifying such inhibitors.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: December 18, 2018
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Patrick A. McKee, Kenneth W. Jackson, Victoria J. Christiansen
  • Patent number: 10109754
    Abstract: Disclosed is at least one embodiment of an infrared (IR) photovoltaic (PV) detector, comprising a IV-VI Lead (Pb)-salt layer disposed on a substrate and a charge-separation-junction (CSJ) structure associated with the IV-VI Pb-salt layer, wherein the CSJ structure comprises a plurality of element areas disposed upon or within the IV-VI Pb-salt layer, wherein the plurality of element areas are spaced apart from each other. Each element area may be connected to a first Ohmic contact thereby forming a plurality of interconnected first Ohmic contacts, and a second Ohmic contact may be disposed upon a portion of the IV-VI Pb-salt layer. In another non-limiting embodiment, a PV detector, comprising a heterojunction region that comprises at least one IV-VI Pb-salt material layer coupled to at least one non-Pb-salt layer, wherein the at least one IV-VI Pb-salt layer and the at least one non-Pb-salt layer form a p-n junction or Schottky junction with a type II band gap alignment.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 23, 2018
    Assignee: The Board of Regents of the University of Oklahoma
    Inventor: Zhisheng Shi
  • Patent number: 10079676
    Abstract: Systems and methods for restoring or recovering linear polarization state of an optical signal as it exits the far end of an optical fiber are disclosed. The optical signal may have an expected pattern of polarization states through a birefringent material of the optical fiber from a first node to a second node. The optical signal may be received by the second node and resulting polarization states may be measured. In certain non-limiting examples, the measured polarization states may be compared to expected polarization states to determine a characterization angle indicative of an axis of the optical fiber.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: September 18, 2018
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Nikhil Vishnu Punekar, Pramode Verma, Gregory Macdonald, Bhagyashri Arun Darunkar, Mayssaa El Rifai
  • Patent number: 10073109
    Abstract: Disclosed are genetically-modified phages, comprising a first nucleic acid sequence encoding at least a first peptide able to bind to a magnetic nanoparticle, and a second nucleic acid sequence encoding at least a second peptide able to bind with high specificity to a predetermined biomarker, and a method for using the genetically-modified phage displaying the first peptide and second peptide in a method for analyzing a fluid sample for the predetermined biomarker.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: September 11, 2018
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Chuanbin Mao, Binrui Cao
  • Patent number: 10033160
    Abstract: An interband cascade (IC) light emitting device comprising a plurality of interband cascade stages, wherein at least one of the IC stages is constructed to have an electron injector made of one or more QWs, a type-I quantum well (QW) active region, a barrier layer positioned between the active region and the electron injector, a hole injector made of one or more QWs, and a barrier layer positioned between the active region and the hole injector. In at least one embodiment, a type II heterointerface layer is between the electron injector and an adjacent hole injector. The well layer of the type-I QW active region has compressive strain, while the barrier layers which flank the type-I QW active region comprise tensile strain layers. In certain embodiments, the electron injector and the hole injector comprise tensile strained layers.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: July 24, 2018
    Assignees: The Board of Regents of the University of Oklahoma, National Research Council of Canada
    Inventors: Rui Q. Yang, James A. Gupta