Abstract: Snapshot Isolation (SI) is an established model in the database community, which permits write-read conflicts to pass and aborts transactions only on write-write conflicts. With the Write Skew Anomaly (WSA) correctly eliminated, SI can reduce the occurrence of aborts, save the work done by transactions, and greatly benefit long transactions involving complex data structures. Embodiments include a multi-versioned memory subsystem for hardware-based transactional memory (HTM) on the GPU, with a method for eliminating the WSA on the fly, and incorporates SI. The GPU HTM can provide reduced compute time for some compute tasks.
Type:
Application
Filed:
June 22, 2018
Publication date:
December 27, 2018
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A method of generating one of podocyte progenitor cells and neural stem/progenitor cells comprising the steps of collecting a urine specimen from a patient; centrifuging the urine specimen; and removing the one of podocyte progenitor cells and neural stem/progenitor cells.
Type:
Grant
Filed:
June 10, 2016
Date of Patent:
December 25, 2018
Assignee:
Board of Supervisors of Louisiana State University
Abstract: An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (?)-?-Pinene, is on the GRAS list (generally recognized as safe).
Type:
Application
Filed:
December 8, 2016
Publication date:
December 20, 2018
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A degassing chamber is disclosed, adapted for the efficient removal of entrained gases from liquids. In a preferred embodiment the degassing chamber is combined with and works in conjunction with a sedimentation tank to provide an efficient clarification station. The combined clarification station can have a “footprint” the same size as, or only slightly larger than, the footprint of the sedimentation tank alone. The degassing chamber is well-suited for retrofitting, and can easily be combined with most types of solid-liquid sedimentation tanks that are currently used in the industry.
Type:
Grant
Filed:
May 22, 2013
Date of Patent:
December 11, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A medical stopcock which allows easier switching operation of plural branch-tubes. The main body of the stopcock comprises a chamber part with a nearly spherical inner surface, and an upstream branch-tube, a downstream branch-tube and a merge-branch-tube all extending from the chamber part. A valve body of the stopcock comprises a nearly spherical valve main body and a rod-shaped operating part with a guide hole linking the inner surface of the chamber part to the outside. In operation, the rod-shaped operating part is moved along the guide hole through the use of the horizontal flow passages and the vertical flow passage to allow the predetermined branch-tubes out of the upstream branch-tube, the downstream branch-tube and the merge-branch-tube to communicate with one another or to shut-off the communication.
Type:
Grant
Filed:
January 23, 2015
Date of Patent:
November 27, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Alireza Hamidian Jahromi, David Hilton Ballard, Jeffery Adam Weisman, Horacio Ruben Vincent D'Agostino
Abstract: The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex virus genomes, recombinant viruses, and immunogenic compositions.
Type:
Grant
Filed:
May 8, 2015
Date of Patent:
November 20, 2018
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat fungal infections. The novel vaccine can provide protective immunity, even for immunocompromised individuals such as HIV patients having reduced levels of CD4+ T cells.
Type:
Application
Filed:
July 13, 2018
Publication date:
November 8, 2018
Applicants:
UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College
Inventors:
Jay K. Kolls, Michael Zheng, Karen Norris, Heather Kling
Abstract: Imaging techniques that may be used in applications such as differential phase contrast imaging are disclosed that include, for example, configuring a beam source and a beam detector such that a beam connects the two, positioning an object, a phase grating and an analyzer grating in the beam path, producing multiple data sets based on various analyzer grating positions, and conducting a regression analysis using a predetermined function having a set of fitting coefficients to establish those fitting coefficients. In those techniques, the fitting coefficients may be used to characterize a set of interference properties associated with the object.
Type:
Grant
Filed:
December 3, 2015
Date of Patent:
November 6, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Leslie G. Butler, Kyungmin Ham, Warren W. Johnson
Abstract: A surface protein of the murine fungal pathogen Pneumocystis murina can be used to generate an immune response in a recipient animal or human that provides prophylactic protection and an anti-fungal activity in subjects already infected with a Pneumocystis species. Further, the disclosure provides novel polypeptides or peptides derived from the P. murina surface protein Surface Peptidase 1 (SPD-1) that are useful, alone or in combination with the SPD-1 polypeptide, in compositions and methods for the generation of an anti-Pneumocystis immune reaction by a recipient subject. The compositions and methods of the disclosure provide advantageous alternatives to available immunogenic determinants for the treatment or prevention of fungal pneumonia.
Type:
Grant
Filed:
May 4, 2015
Date of Patent:
November 6, 2018
Assignees:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY, THE UNIVERSITY OF NEW ORLEANS
Inventors:
Judd E. Shellito, Alistair John Ramsay, David A. Welsh, Sanbao Ruan, Yang Cai
Abstract: Catalysts useful in transforming biomass to bio-oil are disclosed, as are methods for making such catalysts, and methods of transforming biomass to bio-oil. The catalysts are especially useful for, but are not limited to, microwave- and induction-heating based pyrolysis of biomass, solid waste, and other carbon containing materials into bio-oil. The catalysts can also be used for upgrading the bio-oil to enhance fuel quality.
Type:
Application
Filed:
June 21, 2018
Publication date:
November 1, 2018
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as insulin resistance.
Type:
Application
Filed:
November 2, 2017
Publication date:
October 25, 2018
Applicants:
Ipsen Pharma S.A.S., Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Heather A. HALEM, Michael DeWitt CULLER, Andrew A. BUTLER
Abstract: Various examples are provided for carbazole-based GUMBOS (group of uniform materials based on organic salts), and its application in organic light emitting diodes (OLEDs). In one example, a composition includes a solid phase carbazole-based GUMBOS (group of uniform materials based on organic salts) comprising a counterion such as, e.g., trifluoromethanesulfonate ([Otf]), bis-(trifluoromethanesulfonyl)imide ([NTf2]), bis-(pentafluoroethylsulfonyl)imide ([BETI]), tetrafluoroborate (BF4), hexafluorophosphate (PF6), and/or thiocyanate (SCN). The carbazole-based GUMBOS can include carbazoleimidazole-based GUMBOS or 3,6-diBDC carbazolium-based GUMBOS. In another example, a method includes preparing a biphasic solution; separating a layer of DCM from the biphasic solution after stirring; washing the DCM with water to remove byproducts; and evaporating the DCM to form a solid phase carbazoleimidazole-based GUMBOS.
Type:
Grant
Filed:
January 5, 2016
Date of Patent:
October 23, 2018
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Inventors:
Noureen Siraj, Isiah Manuel Warner, Thenahandi Prasanthi Deepthika De Silva
Abstract: Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force microscope to remove and capture a quantity of molecules from the surface, so they can be transferred to a mass spectrometer or another instrument for analysis.
Type:
Grant
Filed:
January 7, 2016
Date of Patent:
October 23, 2018
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY
Inventors:
Kermit King Murray, Suman Ghorai, Chinthaka Aravinda Seneviratne
Abstract: An explant assay based on embryonic tissue from laboratory animals may be used to identify substances that promote neural tube defects—teratogens to be avoided in pregnancy, and substances that inhibit neural tube defects—supplements that might be taken with benefit during pregnancy—to help reduce the incidence of birth defects. The assay screens for compounds that improve or impede mesodermal cell migration from an explant containing the primitive streak and parts of the lateral mesodermal wings that have been dissected from the embryo of a mouse or other experimental animal. Impaired migration of nascent mesodermal cells in the primitive streak is the morphogenetic basis underlying the pathogenesis of neural tube defects. We also hypothesize that maternal diabetes adversely affects mesoderm during gastrulation, before neurulation occurs.
Type:
Application
Filed:
October 26, 2016
Publication date:
October 18, 2018
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Johannes Michael Salbaum, Claudia Kappen
Abstract: A gas detection device comprising a light emitting source including a first plurality of quantum dots of substantially discrete size and made of a semiconductor material a gas cell to contain the gas to be detected and a light detector.
Type:
Grant
Filed:
August 10, 2017
Date of Patent:
October 16, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Embodiments of the present invention include methods for increasing off-chip bandwidth. The method includes designing a circuit of switchable pins, replacing a portion of allocated pins of a processor with switchable pins, connecting the processor to a memory interface configured to switch the switchable pins between a power mode and a signal mode, providing a metric configured to identify which of the power mode and the signal mode is most beneficial during 1 millisecond intervals, and switching the switchable pins to signal mode during intervals where the signal mode provides more benefit than the power mode.
Type:
Grant
Filed:
June 11, 2015
Date of Patent:
October 2, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Lu Peng, Ashok Srivastava, Shaoming Chen
Abstract: A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe.
Type:
Grant
Filed:
May 26, 2015
Date of Patent:
October 2, 2018
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A computer system implementing transactional memory. The computing system includes a plurality of Single Instruction Multiple Thread (SIMT) cores and a conflicting address table (CAT) for each core. The CAT stores word addresses for reads and writes correlated with flags indicating whether a corresponding word is written or read by a committing transaction. The CATs for the different SIMT cores are coupled together by an interconnect. A commit unit (CU) is coupled to the SIMT cores and is configured to validate transactions. The cores access its CAT to access a first address of data affected by a first transaction to be committed at the CU. The first address is compared to a second address affected by a second transaction. When the first address matches the second address, the core delays or prevents committing the first transaction at the CU by pausing the first transaction or aborting the first transaction.
Type:
Application
Filed:
March 13, 2018
Publication date:
September 13, 2018
Applicant:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A new variety of sweetpotato, identified as ‘V12B.445’, is disclosed having disease resistance to both fusarium wilt and Streptomyces soil rot; an orange flesh and purple-red skin, and high yield characteristics.
Type:
Grant
Filed:
October 20, 2016
Date of Patent:
December 4, 2018
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Through The LSU AgCenter
Inventors:
Don R. LaBonte, Christopher A. Clark, Valerio Primomo