Abstract: There is disclosed the use of triprolidine for enabling an individual to wake refreshed after sleep and the method of treating such an individual with triprolidine. The triprolidine is administered shortly before a person wishes to fall asleep, preferably orally and most commonly in the form of a tablet containing less than 5 mg, eg 0.1 mg, 1.25 mg or 2.5 mg, of the active ingredient. The triprolidine is also effective in enabling an individual to sleep more easily.

Abstract: A measuring and dispensing device (2) for attachment to the cap (14) of a bottle (16) of liquid medicine comprises on one of its sides a socket formation (6), by means of which it may be releasably attached to the cap, and on another sid a concave formation (4) for receiving liquid medicine.

Abstract: A dental composition comprises a fluorescent whitening agent. The fluorescent whitening agent is most preferably 4,4?-bis(2-sulfostryryl)bipheny) or a salt or other soluble derivative thereof, eg the disordium salt. The composition may also comprise an additional tooth whitening agent. Methods of whitening the teeth are also described.

Abstract: A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament; (ii) a domperidone medicament and (iii) a carrier material characterized in that the carrier material is substantially free of providone and comprises at least one diluent combined with at least one release modifying agent.

Abstract: A bottle 2 of liquid medicine has a self-sealing closure in its neck 14, the bottle being flexible such that when it is inverted or tilted downwardly, squeezing the bottle produces a flow of liquid medicine through the closure, and releasing the bottle terminates the flow of liquid medicine. The bottle is shaped so as to assist the operation, being of generally box-form, having side walls 6, 8 which support larger front and rear panels 10, which can be controllably flexed.

Abstract: A stable pharmaceutical composition comprising a mixture of (i) an ibuprofen medicament; (ii) a domperidone medicamement; and (iii) a carrier material characterized in that the carrier material is substantially free of povidone and comprises at least one diluent combined with at least one release modifying agent.

Abstract: Hair care compositions containing a synergistic mixture of three anti-free-radical agents selected from (a) ascorbic acid, its salts and esters; (b) tocopherol and its esters, such as tocopherol acetate; and (c) herbal extracts selected from morus alba, origanum vulgare, panax ginseng, rosmarinus officinalis, camellia sinensis and grape seed extract in a suitable diluent or carrier. Preferred synergistic mixtures are Origanum vulgare, sodium ascorbyl phosphate and morus alba. Origanum vulgare, sodium ascorbyl phosphate and panax ginseng. Panax ginseng, morus alba and Origanum vulgare. Sodium ascorbyl phosphate, morus alba and camellia sinensis. Sodium ascorbyl phosphate, morus alba and grape seed Origanum vulgare, panax ginseng and rosmarinus officinalis.

Abstract: The present invention provides a method for eliciting an onset hastened analgesic and anti-inflammatory response and combating nausea in acute migraine attacks. This method comprises administering a pharmaceutical composition comprising more than one active ingredient, wherein said more than one active ingredient consist essentially of: (i) domperidone or an analogue thereof in an amount sufficient to hasten the onset of the analgesic and anti-inflammatory response and to combat nausea in an acute migraine attack, and (ii) a NSAID, a pharmaceutically acceptable salt thereof or a pure (?) or pure (+) optical isomeric form thereof in an analgesically and anti-inflammatory effective amount, wherein said NSAID is selected from the group consisting of proprionic acid derivatives, acetic acid derivatives, fenamic acid derivatives, biphenylcarboxylic acid derivatives and oxicams.

Abstract: There is disclosed the use of triprolidine for enabling an individual to wake refreshed after sleep and the method of treating such an individual with triprolidine. The triprolidine is administered shortly before a person wishes to fall asleep, preferably orally and most commonly in the form of a tablet containing less than 5 mg, e.g. 0.1 mg, 1.25 mg or 2.5 mg, of the active ingredient. The triprolidine is also effective in enabling an individual to sleep more easily. There is also disclosed such uses of, and methods of treating with, consumable films comprising triprolidine, and triprolidine in combination with at least one further active pharmaceutical agent, and consumable films comprising triprolidine in combination with at least one further active pharmaceutical agent.

Abstract: The present invention discloses a topical antimicrobial composition containing high surface area zinc oxide powder, said powder having a surface area between 30 m2/g and 100 m2/g and a particle size between 0.1 and 200 &mgr;m in diameter. The antimicrobial properties of the compositions make them suitable for treating acne, athletes foot, nappy rash and dandruff.

Abstract: The present invention provides a method for eliciting an onset hastened analgesic and anti-inflammatory response and combating nausea in acute migraine attacks.

Abstract: A new cultivar of Rosa plant named ‘Bokramar’ that is characterized by a low-growing habit, decreased susceptibility to disease, and pink flowers that gradually fade giving them a bi-colored appearance. In combination these traits set ‘Bokramar’ apart from all other existing varieties of Rosa known to the inventor.

Abstract: A new cultivar of Rosa plant named ‘Bokrarug’ that is characterized by a compact and flattened globose habit, glossy dark green foliage, cream-yellow buds and white flowers. In combination these traits set ‘Bokrarug’ apart from all other existing varieties of Rosa known to the inventor.