Abstract: The present invention relates to markers for diagnosing the difference in effects of renal cancer treatment or the prognosis of renal cancer patients, according to the gender of renal cancer patients. The survival rate and recurrence rate of renal cancer of a particular gender respectively relate to the mutation of genes, of the present invention, in renal cancer patients, and thus the mutated genes of the present invention can be used as markers in predicting, on the basis of gender, the difference in effects of renal cancer treatment or the prognosis of renal cancer patients.

Abstract: A method for analyzing the methylation level of a specific CpG site in genomic DNA and a composition suitable to use in the method are provided. The method and composition can provide information useful for diagnosing thyroid cancer or determining the prognosis of patients with thyroid cancer. By using the method and the composition, thyroid cancer can be easily and accurately diagnosed from biological samples at a low cost.

Abstract: The present invention relates to a novel complex that is formed by linking p40 subunit and EBI3 subunit via a linker and has excellent anti-inflammatory effects and immunomodulatory effects.

Abstract: The present invention relates to markers for diagnosing the difference in effects of renal cancer treatment or the prognosis of renal cancer patients, according to the gender of renal cancer patients. The survival rate and recurrence rate of renal cancer of a particular gender respectively relate to the mutation of genes, of the present invention, in renal cancer patients, and thus the mutated genes of the present invention can be used as markers in predicting, on the basis of gender, the difference in effects of renal cancer treatment or the prognosis of renal cancer patients.

Abstract: Provided is an aqueous humour discharge apparatus for glaucoma prevention. The aqueous humour discharge apparatus for glaucoma prevention includes: an aqueous humour discharge tube including a contact portion provided on one side and contacting the cornea of an eyeball, an exposed portion exposed not to contact the sclera of the eyeball and provided on the other side, and a channel formed between the contact portion and the exposed portion, to enable aqueous humour to flow therethrough; and a cover member arranged to surround the cornea and the sclera, the cover member including a contact hole formed on one surface that contacts the cornea, and contacted by the aqueous humour discharge tube, a discharge hole formed on the other surface located on the opposite side to the one surface and exposed to the outside, to discharge the aqueous humour, and a flow channel provided between the contact hole and the discharge hole to provide a discharge path of the aqueous humour.

Abstract: Disclosed are a screening apparatus using a multi-channel array electrode probe and a method of operating the screening apparatus, wherein the screening apparatus includes a probe inserted into the inside of the human body and including a plurality of electrodes in contact with any one portion of the inside and an endoscope camera for photographing the portion; a location identifier for identifying a location in contact with the electrodes in an image photographed by the endoscope camera; an electrical property measuring device for measuring the electrical properties of the identified location; a mapping processor for mapping the measured electrical properties to an electrical model for the internal tissue; and a visualization information generator for, based on the mapping results, generating visualization information for visualization of the degree of deformation of the tissue with respect to the measured electrical properties.

Abstract: The present invention relates to pH-sensitive carbon nanoparticles, a method of preparing the same, and a drug delivery using the same, and pH-sensitive carbon nanoparticles including imidazole is prepared so that a hydrophobic drug and a photosensitizer material can be encapsulated, drug release is possible under weakly acidic conditions, and thus it can be used as a drug carrier for anticancer treatment, photodynamic therapy, or photomediated anticancer immunotherapy.

Abstract: The present invention relates to a biomarker and uses thereof for liver cancer diagnosis or prognosis prediction. The biomarker according to the present invention may be used as a marker for liver cancer diagnosis and prognosis prediction with improved specificity and sensitivity. Thus, the biomarker may be used not only to diagnose or prognose liver cancer with high accuracy and reliability, but also to effectively screen a liver cancer treatment agent.

Abstract: A nucleic acid molecule including at least one expression control sequence having an Internal Ribosomal Entry Site (IRES) sequence, at least one coding region, and optionally multiple adenosines or thymidines upstream of the at least one expression control sequence is disclosed as an expression system. Besides, a recombinant expression vector including the nucleic acid molecule and pharmaceutical or medicinal use of the nucleic acid molecule are disclosed.

Abstract: Provided is a customizable surgical bone-cutting jigsaw puzzle-type guide device. The customizable surgical bone-cutting jigsaw puzzle-type guide device includes: a main guide portion that includes a main contact surface lengthily formed along a required main incision line of a bone to be cut and shaped to be brought into contact with the bone, and a main guide surface forming a guide line together with the main contact surface along the same line as the main incision line and shaped to be brought into contact with a cutting blade for guiding the movement of the cutting blade during cutting of the bone; and a connection portion extending from the main guide portion and connected to a side of the bone such that the main guide portion may be supported on the bone, the connection portion being configured to be detachably attached to the side of the bone.

Abstract: The present invention relates to a polymer complex for recognizing Helicobacter pylori and its uses, and in more detail, a water-soluble polymer-photosensitizer complex in which sialyllactose, which selectively binds to the surface of Helicobacter pylori, is conjugated, has excellent selectivity and binding power to the Helicobacter pylori strain, and the photosensitizer in the complex generates singlet oxygen when irradiated with laser to effectively induce the inactivation of Helicobacter pylori and it is intended to provide the complex as a polymer complex for recognizing Helicobacter pylori to effectively detect Helicobacter pylori in the gastrointestinal tract and to provide a Helicobacter pylori photodynamic therapy to solve the conventional antibiotic resistance problem.

Abstract: The present invention relates to a urine test container, Specifically, the present invention relates to a container capable of readily separating first urine while receiving whole urine in order to remove the inconvenience of discarding the first urine and putting the remaining urine in a container in a medical institution such as a hospital and a health care institution, because the quality of a test is decreased due to a plurality of epithelial cells included in the first urine in a urine test.

Abstract: There is provided an intraocular lens including an optic portion having a circular shape from one side thereof and including a first pattern which includes a ridge and a groove, and a plurality of haptic portions extending from an outer circumferential edge of the optic portion and each including a second pattern which includes a ridge and a groove, in which at least one of the ridges included in the first pattern and the second pattern and at least one of the grooves included in the first pattern and the second pattern includes a section in which a width is formed differently.

Abstract: A system to align an object using a light reflector, including: an input unit for pre-setting a first region in which radiation is to be emitted to the object; a display unit for displaying information on the first region; a radiation unit for emitting radiation to the first region; a reflector formed to correspond to the shape of the first region and configured to be attached to the first region; a light unit for emitting light in the same direction as the radiation to the first region; a camera for photographing a region of the reflector when the reflector reflects light emitted by the light unit; and a control unit for controlling the display unit to display the region of the light reflector which reflects light photographed by the camera, and determining whether the radiation is aligned to the first region of the object based on whether the region of the light reflector is included in the shape of the first region.

Abstract: The present invention provides a peptide nucleic acid probe including any one or more selected from the group consisting of nucleic acid sequences represented by SEQ ID NOs: 7-10 and nucleic acid sequences complementary to the nucleic acid sequences, and manufactured so as to complementarily bind to a BCR/ABL negative myeloproliferative neoplasm-associated gene, thereby enabling multiplex detection of gene mutations; a composition for multiplex detection of gene mutations comprising the same; a kit; and a method for multiplex detection of BCR/ABL negative myeloproliferative neoplasm-associated gene mutations using the same. Therefore, since multiplex detection of BCR/ABL negative myeloproliferative neoplasm-associated gene mutations can be rapidly and accurately carried out by one detection process, BCR/ABL negative myeloproliferative neoplasm is effectively diagnosed, and thus the present invention can be useful for diagnosis, follow-up, prognosis estimation, and treatment of diseases.

Abstract: A method of diagnosing a periodontal condition using a protein showing a concentration difference between periodontal tissue in a normal condition and an abnormal condition from a subject's saliva is provided. According to this non-invasive method, the patient himself is able to check the presence of periodontal disease and identify the time to receive a treatment at an early stage, which will allow the patient to save time and cost for the treatment of periodontitis.

Abstract: A method for producing a sample slice includes providing a disk, providing a jig on the disk for supporting side portions of a material, providing the material inside the jig, providing a pillar assembly on the jig, the pillar assembly that includes a first base member having a plurality of through holes, a second base member detachably mounted to said first base member, and a plurality of pillars supported between said first and second base members and arranged to be exposed through the plurality of holes, inserting the plurality of pillars into the material, solidifying the material, separating the jig and the pillar assembly to remove the material from the jig, and cutting a sample slice from the material with a cutter.

Abstract: The present disclosure relates to a calculus removing device which is used in the medical field. More particular, the present disclosure relates to a calculus removing device which has a lithotripsy probe capable of simultaneously destructing and removing the calculus formed in the human body regardless of the size of the calculus by optionally using attractivity or electricity through a lithotripsy probe.

Abstract: The present invention provides a vertebral implant cage for oblique lumbar interbody fusion surgery, comprising: a first member (110) to be inserted between vertebral bodies; a second member (120) coupled to a front surface of the first member; a screw hole (125) formed through the second member; a screw (130) fastened to the screw hole; and a vertical coupling hole (115) vertically formed through the first member so as to couple the second member thereto, wherein the second member can slide a predetermined distance along the front circumference of the first member while being coupled to the vertical coupling hole.