Patents Assigned to The Chancellor, Masters and Scholars of the University of Oxford
  • Inhibition of glycolipid biosynthesis
    Patent number: 6465488
    Abstract: Methods for treating lipid storage diseases using compounds that inhibit glucosyltransferase enzymes are disclosed herein. The invention relates to the treatment of lipid storage disease with compounds that inhibit glucosyltransferase activity in the affected cells. It relates particularly to the use of 1,5-dideoxy-1,5-imino-D-glucitol and derivatives thereof.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: October 15, 2002
    Assignee: Chancellor, Masters & Scholars of the University of Oxford
    Inventors: Terry D. Butters, Frances M. Platt, Raymond A. Dwek
  • Recombinant .alpha.-2,3-sialyltransferases and their uses
    Patent number: 6096529
    Abstract: The structure and specificity of the recombinant .alpha.-2,3-sialyltransferases from Neisseria spp, are disclosed. Their use in the production of desired carbohydrate structures is also provided.
    Type: Grant
    Filed: June 7, 1997
    Date of Patent: August 1, 2000
    Assignees: National Research Council of Canada, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Michel Gilbert, Warren W. Wakarchuk, Martin N. Young, Michael P. Jennings
  • Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
    Patent number: 5591430
    Abstract: Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These "TRAS" bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.
    Type: Grant
    Filed: June 17, 1994
    Date of Patent: January 7, 1997
    Assignees: Ludwig Institute for Cancer Research, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Alan Townsend, Judy Bastin, Thierry Boon-Falleur, Pierre van der Bruggen, Pierre Coulie, Thomas Gajewski
  • Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
    Patent number: 5585461
    Abstract: Tumor rejection antigens derived from tumor rejection precursor MAGE-3 have been identified. These "TRAS" bind to the MHC-class I molecule HLA-A2, and the resulting complexes stimulate the production of cytolytic T cell clones which lyse the presenting cells. The peptides and complexes may be used diagnostically, therapeutically, and as immunogens for the production of antibodies, or as targets for the generation of cytolytic T cell clones.
    Type: Grant
    Filed: March 24, 1994
    Date of Patent: December 17, 1996
    Assignees: Ludwig Institute for Cancer Research, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Alan Townsend, Judy Bastin, Thierry Boon-Falleur, Pierre van der Bruggen, Pierre Coulie
  • Memory device that functions as a content addressable memory or a random access memory
    Patent number: 5408434
    Abstract: A programmable logic device is disclosed which can be used either as a look-up table logic device or as a logic function generator. This enables combinations to be provided such as the combination of a look-up table with a fixed gate field programmable gate array.
    Type: Grant
    Filed: February 3, 1994
    Date of Patent: April 18, 1995
    Assignees: Inmos Limited, Chancellor, Masters and Scholars of the University of Oxford
    Inventor: Anthony I. Stansfield
  • Electrophoresis method and apparatus for separating particles in a separation medium
    Patent number: 4886589
    Abstract: Electrophoresis method and apparatus for separating particles in a separan medium (15) in which provided for driving the particles alternatively in different directions in the separation medium (15). The separation medium (15) is rotated at predetermined intervals in a plane between different rotary positions in one and the same electric field.
    Type: Grant
    Filed: May 28, 1987
    Date of Patent: December 12, 1989
    Assignee: The Chancellor, Masters and Scholars of the University of Oxford
    Inventor: Edwin Southern