Abstract: An in vitro method for the identification and quantification of glycated human serum albumin to assess the extent of diabetic complications in diseased individuals. Further, a diagnostic kit for identifying the extent of diabetes in a diseased individual by estimating glycated serum albumin levels in such individuals.

Abstract: Disclosed is a cheap and efficient non noble metal based catalyst for the oxidation of diesel or hydrocarbons, its synthesis and its application for diesel oxidation at low temperature. The catalyst comprises a mixed oxide of manganese and cerium, or manganese, cerium and zirconium. The catalyst has improved water and sulphur tolerance.

Abstract: The present invention relates to a novel cloning, expression and refolding process for preparing antibody fragments. More particularly, the present invention relates to a cloning, expression and refolding platform for preparing recombinant humanized (rHu) Ranibizumab.

Abstract: The present invention relates to the design and development of recombinant protein for the delivery of silencer RNA complex to mediate RNA interference since it represents a novel therapeutic approach to modulate several neurodegenerative disease-related genes across the blood-brain barrier (BBB). To overcome challenges due to this barrier for biologics and other biological complex, the present invention describes a method wherein peptide having sequence GGGGHLNILSTLWKYRC represented by SEQ ID NO. 1 known to target specific gangliosides was linked to a double-stranded RNA binding protein to bind and deliver silencer RNA to the brain parenchyma. The designed fusion protein comprising a double-stranded RNA-binding domain (dsRBD) of human Trans Activation response element (TAR) RNA Binding Protein (TARBP2) and a brain targeting peptide sequence that binds GM1. Conformation-specific binding of TARBP2 domain to silencer RNA results in the formation of homogenous serum-stable complex with GM1 targeting potential.

Abstract: The present invention discloses a water oxidation catalyst having composition ZnxCo(3-x)O4 for splitting water into oxygen and hydrogen gas and a process for the preparation thereof.

Abstract: A lubricant formulation of carbamoylethyl katira and a microwave assisted process for the preparation of the lubricant formulation of carbamoylethyl katira. The lubricant formulation of carbamoylethyl katira having antibacterial activity useful for eye lubricant based formulations, treatment of dry eye disease syndrome, etc.

Abstract: The present invention provides a process for the preparation of phosphor aerogel of uniform size having high porosity, low density; high thermal insulation and high luminescence, which is useful for various applications like lighting, display, sensing and other applications. More specifically, the present invention provides a simple and versatile process for the formation of monolithic gel, at room temperature, which on further drying at supercritical temperature and pressure result in dry aerogel.

Abstract: The present invention discloses a process for the dissociation of natural gas hydrates comprises injecting additives or hydrate dissociation promoters into the system at the hydrate dissociation temperatures ranging from 283-293 K in conjunction with or without first depressurizing the system to pressures (50%-75%) below the hydrate equilibrium pressure and such leading to the recovery of methane or natural gases.

Abstract: The invention discloses a composition comprising surface modified iron oxide nanoparticles with citric acid modified cyclodextrin with a hydrodynamic diameter of less than 10 nm and a hydrophobic molecule. The composition finds use in targeted delivery of a hydrophobic drug and as contrast agent in imaging applications.

Abstract: An Internet of Things (IoT) based system for remotely monitoring and controlling various physical parameters for chemical/biological material under transportation in a container is disclosed herein. Due to various circumstances, wither hazardous or infectious, taking proper measures becomes a necessary condition while transporting chemical or biological materials. The sensors attached to the container measure the associated physical parameters and send the data to a remote control system. The dynamic barcode responds to the change in any of the parameters and changes its patterns accordingly. The remote server, based on the received data, instructs a controlling system to control the parameters, thus maintaining the health of the material.

Abstract: The patent relates to para amino benzoic acid (pABA) sensitized terbium (Tb3+) doped spherical LaF3 nanoparticles used for detection of nitro group containing compounds using the terbium (Tb3+) doped spherical LaF3 nanoparticles sensitized by para amino benzoic acid (pABA).

Abstract: The invention relates to a material, process and method for the selective analysis of small molecules. Particularly the invention provides a material and a technique for the analysis of small molecules excluding other large molecular weight (MW) analytes. The process involves selective detection of low molecular weight molecules from a sample comprising the steps of placing said sample with SBA-15 particles; and subjecting the same to desorption ionization mass spectrometry, wherein low molecular weight molecules are selectively detected over the higher molecular weight molecules. A kit for the selective analysis of small molecules is also provided.

Abstract: The present invention discloses a Plectin-1 receptor targeting novel cationic KTLLPTPK(SEQ ID NO: 1)-lipopeptide. The present invention further discloses a liposomal formulation comprising the cationic KTLLPTPK(SEQ ID NO: 1)-lipopeptide, at least two co-lipids, a therapeutic agent, and a pharmaceutically acceptable carrier. The present invention also provides a method for regressing established pancreatic tumors comprising administering a therapeutically effective amount of the liposomal formulation with the therapeutic agents in combination with targeted genetic immunization (DNA vaccination) i.e. by immunizing mice with electrostatic complexes (direct in-vivo DC-targeting cationic liposomes) of DNA vaccines encoding mesothelin (p-CMV-MSLN).

Abstract: The present invention discloses a novel eco-friendly, cost effective, autocatalytic process for the synthesis of tributyl citrate (TBC) with high yields and purity.

Abstract: A method for prevention and/or treatment of diminution of bone tissue using a composition comprising a compound selected from Withaferin A (WFA), Withanolide A, and Withanone. The composition showed enhanced WFA bioavailability in rodents against plain WFA, promotes bone marrow cell differentiation, and increases the percent of bone volume to tissue volume (BV/TV %) by 3 folds as compared to free Withaferin A (WFA).

Abstract: The invention relates to synthesis of methyl carbamate (MC) and dimethyl carbonate (DMC) in presence of stripping inert gas or superheated methanol vapors using packed column reactor and bubble column reactor.

Abstract: Disclosed are 3-indolyl furanoid compounds which are useful as potent anti-inflammatory agents and prevent gastric ulcer by inhibiting matrix metalloproteinase-9 (MMP-9) expression in gastric mucosal layer. For example, disclosed is a compound of formula 1, wherein: R1 to R6 is selected from H, OH, CH3, OCH3, Br, Cl, Ph or o-OHC6H4, OCH2—CH?CH2, or OCH2CH2CH3, and R1 to R6 is having at least one substituent with alkyl, aryl and heteroaryl groups other than H, wherein the carbon in alkyl, aryl and heteroaryl is in the range of C1 to C8. Various embodiments relate to representative compounds of Formula 1 and method of preparation thereof. Further embodiments relates to the use of representative compounds of Formula 1 in treating diseases associated with gastric ulcer and other inflammatory diseases. A noted feature of an embodiment is the IC50 value of 50 ?M of one of the 3-indolyl furanoids.

Abstract: The present invention relates to the diagnostic methods for identification of the single causative agent or more than one causative agent of ocular and nervous system infections among many probable pathogens, which can cause the infection. All the pathogens affecting a discrete area of eye or nervous system generally cause same clinical manifestations or syndromes. The present invention relates to detection and discrimination of the pathogen among the set of probable pathogens in a single test without resorting to a battery of tests each being directed at detection of one pathogen. The current invention aims at the syndrome based diagnostic replacing the diagnostics based on detection of individual pathogens.

Abstract: The present invention relates to method of treating chronic myeloid leukemia (CML) or drug resistant CML comprising, administering to human being or any other mammal or animal in need thereof, a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition; or a combination of a therapeutically effective amount of Clofazimine (CFZ) or its pharmaceutically acceptable derivative, analogue, salt or composition with a tyrosine kinase inhibitor (TKI). The invention also provides the kit for treatment of CML or drug resistant CML.

Abstract: The present invention relates to the cloning and expression of cDNA encoding O-methyl transferase for catalyzing the synthesis of vital volatile flavor compounds such as mesifuran and vanillin, thereby playing a significant role in flavor biochemistry of mango. The present invention also provide a process for the preparation of volatile compounds by mesifuran, ferulic acid, guaiacol and vanillin, specifically mesifuran and vanillin using cDNA sequence.