Patents Assigned to The Foundry, LLC
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Patent number: 9463010Abstract: A knotless suture anchoring system includes an outer anchor having a central channel and a distal tip adapted to penetrate tissue. An inner anchor is positionable in the central channel of the outer anchor and a locking feature on one or both of the inner and outer anchors retains the inner anchor within the central channel. A continuous length of suture is coupled with the inner and outer suture anchors and has a free end. At least one of the inner and the outer anchors also has a cinching mechanism that allows the suture to be tensioned by passage of the suture through the cinching mechanism in a first direction while movement of the suture through the cinching mechanism in a second direction opposite the first direction is constrained.Type: GrantFiled: January 24, 2013Date of Patent: October 11, 2016Assignee: The Foundry, LLCInventors: Darin C. Gittings, Mark Deem, Michael Hendricksen, Vivek Shenoy, Hanson S. Gifford, III, Stephen Boyd
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Patent number: 9408688Abstract: Devices and methods for treating aneurysms, such as abdominal aortic aneurysms (“AAA”) generally include one or more stent-graft devices. Some embodiments include self-expanding and/or balloon-expandable stent components and one or more graft components coupled with the stent components. Using various combinations of self-expanding stent members, balloon-expandable stent members, graft members, and/or anchoring members enhances the anchoring abilities of a stent-graft device to prevent leakage around it, and may further allow the device to be adjusted after placement at a site for treatment. Some embodiments further include a skirt graft member for further prevention of leakage and/or device slippage.Type: GrantFiled: February 5, 2014Date of Patent: August 9, 2016Assignee: The Foundry, LLCInventors: Mark Deem, Hanson S. Gifford, III, Bernard Andreas, Sunmi Chew, Ron French, Doug Sutton
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Patent number: 9327104Abstract: A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form that inhibits mucus production, and a delivery device. Actuation of the foam generating mechanism entraps gaseous bubbles from the gas in the liquid thereby forming a foam. The therapeutic agent is dispersed in the foam which has an expanded configuration adapted to fill a nasopharyngeal space and deliver the therapeutic agent to the mucosa targets. The delivery device is for delivering the foam to the nasopharyngeal space. The foam may also have a collapsed configuration for removal from the nasopharyngeal space or for concentration of the therapeutic agent onto the mucosa.Type: GrantFiled: January 9, 2014Date of Patent: May 3, 2016Assignee: The Foundry, LLCInventors: John Morriss, Cary Reich, Hanson Gifford
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Patent number: 9302125Abstract: Methods and apparatus are provided that enable a physician to image tissue within the body that is to be ablated, and then to ablate that tissue using a device having an ultrasound imaging system and an aligned high intensity focused ultrasound system.Type: GrantFiled: July 26, 2006Date of Patent: April 5, 2016Assignee: The Foundry, LLCInventors: Hanson S. Gifford, Mark E. Deem
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Patent number: 8961391Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.Type: GrantFiled: October 25, 2012Date of Patent: February 24, 2015Assignee: The Foundry, LLCInventors: Mark E. Deem, Hanson S. Gifford
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Publication number: 20140242064Abstract: A system for delivering a therapeutic agent to a nasopharyngeal mucosa target comprises a foam generating mechanism, a gas, a therapeutic agent in liquid form that inhibits mucus production, and a delivery device. Actuation of the foam generating mechanism entraps gaseous bubbles from the gas in the liquid thereby forming a foam. The therapeutic agent is dispersed in the foam which has an expanded configuration adapted to fill a nasopharyngeal space and deliver the therapeutic agent to the mucosa targets. The delivery device is for delivering the foam to the nasopharyngeal space. The foam may also have a collapsed configuration for removal from the nasopharyngeal space or for concentration of the therapeutic agent onto the mucosa.Type: ApplicationFiled: January 9, 2014Publication date: August 28, 2014Applicant: The Foundry, LLCInventors: John Morriss, Cary Reich, Hanson Gifford
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Publication number: 20140243793Abstract: A system for delivering a therapeutic agent to nasopharyngeal mucosa tissue has a shaft, a porous pad of compliant material coupled to the shaft near the distal end, and a drug reservoir. The porous pad is configured to expand from a contracted configuration to an expanded configuration. The expanded configuration is adapted to engage and conform to the mucosa tissue in a nasal cavity, and the contracted configuration has a size suitable for introduction into the nasal cavity. The drug reservoir holds a therapeutic agent and is at least partially covered by the porous pad. The drug reservoir is configured to release a fixed volume of the therapeutic agent into the porous pad within a period of less than about 120 minutes, and has a wall with a plurality of channels fluidly coupled with the porous pad.Type: ApplicationFiled: January 9, 2014Publication date: August 28, 2014Applicant: The Foundry, LLCInventors: John Morriss, Hanson Gifford
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Publication number: 20140155984Abstract: Devices and methods for treating aneurysms, such as abdominal aortic aneurysms (“AAA”) generally include one or more stent-graft devices. Some embodiments include self-expanding and/or balloon-expandable stent components and one or more graft components coupled with the stent components. Using various combinations of self-expanding stent members, balloon-expandable stent members, graft members, and/or anchoring members enhances the anchoring abilities of a stent-graft device to prevent leakage around it, and may further allow the device to be adjusted after placement at a site for treatment. Some embodiments further include a skirt graft member for further prevention of leakage and/or device slippage.Type: ApplicationFiled: February 5, 2014Publication date: June 5, 2014Applicant: The Foundry, LLCInventors: Mark Deem, Hanson S. Gifford, III, Bernard Andreas, Sunmi Chew, Ron French, Doug Sutton
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Publication number: 20140121097Abstract: A catalyst structure comprising dispersed metal catalyst on support, wherein the support but not the metal catalyst can be observed using x-ray diffraction, and wherein the metal catalyst can be chemically detected.Type: ApplicationFiled: September 24, 2013Publication date: May 1, 2014Applicant: The Materials Foundry, LLCInventors: Jonathan Phillips, Brian James Scanlan
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Publication number: 20140114233Abstract: Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity.Type: ApplicationFiled: December 23, 2013Publication date: April 24, 2014Applicant: The Foundry, LLCInventors: Mark E. Deem, Hanson Gifford
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Patent number: 8679171Abstract: Devices and methods for treating aneurysms, such as abdominal aortic aneurysms (“AAA”) generally include one or more stent-graft devices. Some embodiments include self-expanding and/or balloon-expandable stent components and one or more graft components coupled with the stent components. Using various combinations of self-expanding stent members, balloon-expandable stent members, graft members, and/or anchoring members enhances the anchoring abilities of a stent-graft device to prevent leakage around it, and may further allow the device to be adjusted after placement at a site for treatment. Some embodiments further include a skirt graft member for further prevention of leakage and/or device slippage.Type: GrantFiled: March 1, 2004Date of Patent: March 25, 2014Assignee: The Foundry, LLCInventors: Mark Deem, Hanson S. Gifford, III, Bernard Andreas, Sunmi Chew, Ron French, Doug Sutton
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Patent number: 8636684Abstract: Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity.Type: GrantFiled: December 16, 2011Date of Patent: January 28, 2014Assignee: The Foundry LLCInventors: Mark E. Deem, Hanson Gifford
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Publication number: 20130345715Abstract: The present invention provides devices and methods for decalcifying an aortic valve. The methods and devices of the present invention break up or obliterate calcific deposits in and around the aortic valve through application or removal of heat energy from the calcific deposits.Type: ApplicationFiled: December 3, 2012Publication date: December 26, 2013Applicant: The Foundry, LLCInventors: Hanson S. Gifford, Mark E. Deem, Stephen Boyd
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Publication number: 20130303948Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.Type: ApplicationFiled: October 25, 2012Publication date: November 14, 2013Applicant: The Foundry, LLCInventors: Mark E. Deem, Hanson S. Gifford
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Publication number: 20130231671Abstract: A method of treating a patient's joint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.Type: ApplicationFiled: September 15, 2012Publication date: September 5, 2013Applicant: The Foundry, LLCInventors: David Boudreault, Vivek Shenoy, Hanson S. Gifford, Mark Deem, Michael Hendricksen, Doug Sutton
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Publication number: 20130131444Abstract: A method of treating a patient's joint having opposing joint surfaces includes providing an elongate member having a proximal end, a distal end and an expandable member near the distal end. The expandable member is positioned in the joint between the joint surfaces and expanded so as to separate the joint surfaces away from one another into a distracted position. The joint is manipulated while in the distracted position so that the joint is distracted and in flexion. A diagnostic or therapeutic procedure is then performed on the joint while maintaining the joint in the flexed and distracted position.Type: ApplicationFiled: September 14, 2012Publication date: May 23, 2013Applicant: The Foundry, LLCInventors: David BOUDREAULT, Vivek SHENOY, Hanson S. GIFFORD, Mark DEEM, Michael HENDRICKSEN, Doug SUTTON
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Patent number: 8338164Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.Type: GrantFiled: October 5, 2011Date of Patent: December 25, 2012Assignee: The Foundry, LLCInventors: Mark E. Deem, Hanson Gifford
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Publication number: 20120178988Abstract: A surgical device for reinforcing the pericardial sac surrounding the heart to assist in the treatment of congestive heart failure includes an enclosure having an interior and an exterior. The interior surface limits adhesions or accepts ingrowth with the myocardial tissue of the epicardium. The exterior surface is adapted to adhere to or otherwise attach to the pericardium to provide reinforcement.Type: ApplicationFiled: March 22, 2012Publication date: July 12, 2012Applicant: The Foundry, LLCInventors: Ronald G. French, Sunmi K. Chew, Hanson S. Gifford, III, Bernard H. Andreas
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Publication number: 20120089078Abstract: Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity.Type: ApplicationFiled: December 16, 2011Publication date: April 12, 2012Applicant: The Foundry, LLCInventors: Mark E. Deem, Hanson Gifford
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Patent number: D690970Type: GrantFiled: February 28, 2012Date of Patent: October 8, 2013Assignee: The Platypus Foundry, LLCInventors: Derek Boirun, Joseph Blumenthal, John Gutman