Abstract: In some embodiments, a method for mitigating interference in a channel having multiple users can include: determining a starting angle based on a direction of a signal of interest (SOI); iteratively steering a beam away from the starting angle in opposite directions and calculating a grade of the beam; choosing the beam at a current angle as a receive beam based on the beam grade; receiving a signal using the receive beam; and decoding the SOI from one or more interfering signals using successive interference cancellation multi-user detection (SIC MUD) on the received signal.

Abstract: A system and a method for controlling a system are described. The system includes a plurality of sensors configured to be worn on a user's body. The plurality of sensors are configured to generate a plurality of signals in response to forces applied by corresponding portions of a user's body. The system also includes a processor configured to receive the plurality of signals. The processor is configured to identify commands from the user based at least partly on the plurality of signals and an operational range and/or null space of the plurality of signals for a task being performed by the user. The processor is configured to control an operation of the system based on the identified commands.

Abstract: Optical microcavity resonance measurements can have readout noise matching the fundamental limit set by thermal fluctuations in the cavity. Small-heat-capacity, wavelength-scale microcavities can be used as bolometers that bypass the limitations of other bolometer technologies. The microcavities can be implemented as photonic crystal cavities or micro-disks that are thermally coupled to strong mid-IR or LWIR absorbers, such as pyrolytic carbon columns. Each microcavity and the associated absorber(s) rest on hollow pillars that extend from a substrate and thermally isolate the cavity and the absorber(s) from the rest of the bolometer. This ensures that thermal transfer to the absorbers is predominantly from radiation as opposed to from conduction. As the absorbers absorb thermal radiation, they shift the resonance wavelength of the cavity.

Abstract: The present disclosure provides a novel machine learning model capable of assisting those of ordinary skill in the art to conduct base editing by, inter alia, facilitating the selection of an appropriate guide RNA and base editor combination which are capable of conducting base editing at a certain level of efficiency and specificity on a given input target DNA sequence desired to be edited to produce an outcome genotype of interest. The disclosure also provides base editors (e.g., ABEs and CBEs), napDNAbps, cytidine deaminases, adenosine deaminases, nucleic acid sequences encoding base editors and components thereof, vectors, and cells. In addition, the disclosure provides methods of making biological or experimental training and/or validation data for training and/or validating the machine learning computational models, as well as, vectors, libraries, and nucleic acid sequences for use in obtaining said experimental training and/or validation data.

Abstract: Composite anti-fouling coatings and associated systems and methods are generally described. In some aspects, a system comprises a substrate, a composite coating disposed on at least a portion of the substrate, and a fluid comprising one or more foulants, where the composite coating is configured to be in physical contact with the fluid during use. The composite coating may comprise a first region comprising a first material and a second region comprising a second material that is different from the first material. According to some embodiments, a full- spectral Hamaker constant associated with the composite coating and the fluid (i.e., based on average optical properties of the first and second materials of the composite coating) is relatively low, and the van der Waals (vdW) force between the composite coating and the one or more foulants is, therefore, correspondingly low. Under some conditions (e.g.

Abstract: Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein: wherein m, n, p, R?, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

Abstract: The present disclosure, at least in part, relates to a miRNA based logic gate that comprises an engineered RNA carrier that comprises an nuclear export signal, a target site for a first miRNA and a pre-miRNA sequence for a second miRNA. Also provided by the disclosure are recombinant viruses (e.g., recombinant adeno-associated viruses (rAAV)) for delivery of the miRNA based logic gates.

Abstract: Techniques are disclosed for an adaptive and causal random linear network coding (AC-RLNC) with forward error correction (FEC) for a communication channel with delayed feedback. An example methodology implementing the techniques includes transmitting one or more coded packets in a communication channel, determining a channel behavior of the channel, and adaptively adjusting a transmission of a subsequent coded packet in the first channel based on the determined channel behavior. The communication channel may be a point-to-point communication channel between a sender and a receiver. The channel behavior may be determined based on feedback acknowledgements provided by the receiver. The subsequent coded packet may be a random linear combination of one or more information packets.

Abstract: The present disclosure relates to a method of sequencing nascent RNA in a cell. In some embodiments, the nascent RNA is conjugated to DNA using copper-catalyzed azide-alkyne cycloaddition (CuAAC). Methods of the present disclosure can be used to generate genomic libraries of a cell and measure gene expression and enhancer and/or super-enhancer activity.

Abstract: A lithium ion conductor includes a compound of Formula 1: Li7-a*?-(b-4)*?-xMa?La3Zr2-?Mb?O12-x-?XxN???Formula 1 wherein in Formula 1, Ma is a cationic element having a valence of a, Mb is a cationic element having a valence of b, and X is an anion having a valence of ?1, wherein, when Ma comprises H, 0???5, otherwise 0???0.75, and wherein 0???1.5, 0?x?1.5, (a*?+(b?4)?+x)>0, and 0<??6.

Abstract: An artificial muscle system includes a collapsible skeleton, a flexible skin, and a muscle actuation mechanism. The collapsible skeleton is contained inside a volume defined, at least in part, by the flexible skin. The flexible skin and the collapsible skeleton are configured for the flexible skin to provide a pulling force on the collapsible skeleton when a pressure difference exists between the inside of the sealed volume and a surrounding environment to change at least one of the dimensions and thus geometry of the collapsible skeleton. The muscle actuation mechanism includes at least one of the following to deploy or contract the collapsible skeleton: (a) a fluid displacing, releasing, or capturing mechanism configured to increase or decrease fluid pressure inside the sealed volume; and (b) a heating or cooling element configured to change the temperature of fluid in the sealed volume.

Abstract: Disclosed are vapor transport deposition systems and methods for alternating sequential vapor transport deposition of multi-component perovskite thin-films. The systems include multiple vaporizing sources that are mechanically or digitally controlled for high throughput deposition. Alternating sequential deposition provides faster sequential deposition, and allows for reduced material degradation due to different vapor temperatures.

Abstract: When imaging bright objects, a conventional detector array can saturate, making it difficult to produce an image with a dynamic range that equals the scene's dynamic range. Conversely, a digital focal plane array (DFPA) with one or more m-bit counters can produce an image whose dynamic range is greater than the native dynamic range. In one example, the DFPA acquires a first image over a relatively brief integration period at a relatively low gain setting. The DFPA then acquires a second image over longer integration period and/or a higher gain setting. During this second integration period, counters may roll over, possibly several times, to capture a residue modulus 2m of the number of counts (as opposed to the actual number of counts). A processor in or coupled to the DFPA generates a high-dynamic range image based on the first image and the residues modulus 2m.

Abstract: The present invention provides methods of inducing proliferation of and/or differentiating cells comprising contacting cells with compounds within the methods of the invention. The present invention further provides cells obtainable by the methods of the invention.

Abstract: In some embodiments, a method for mitigating interference in a channel having multiple users includes: receiving a plurality of signals from a plurality of antenna elements, the received signals comprised of one or more interfering signals and a signal of interest (SOI); for each of the one or more interfering signals, beamforming the received signals to enhance the interfering signal, generating an estimate of the interfering signal, and adjusting the estimated interfering signal to undo the effects of beamforming; and subtracting each of the estimated interfering signals from each of the received signals to generate a plurality of interference-mitigated received signals.

Abstract: An insertable catheter device includes a shaft including a proximal end and a distal end, an expandable balloon, and an actuator configured to expand and retract the expandable balloon. The actuator includes a fluid conduit that extends through the shaft and is coupled with the expandable balloon to enable inflation and retraction of the expandable balloon via injection or withdrawal of a fluid to or from the expandable balloon via the fluid conduit. The expandable balloon is displaceably retractable into the shaft and extendable from the shaft. A fluid pump is coupled with the fluid conduit to pump the fluid through the fluid conduit. A patch is positioned to be displaced by the expandable balloon when the expandable balloon is inflated, and the expandable balloon is displaceably retractable into the shaft and displaceably extendable from the shaft.

Abstract: The present invention provides isolated immune cells, immune cell populations and compositions, as well as markers, marker signatures and molecular targets characterising the immune cells. The cell products, substances, compositions, markers, marker signatures, molecular targets, kits of parts and methods of the present invention provide for new ways to characterise, evaluate and modulate the immune system and immune responses.

Abstract: In one aspect of the present disclosure, method includes: receiving neural data responsive to a listener's auditory attention; receiving an acoustic signal responsive to a plurality of acoustic sources; for each of the plurality of acoustic sources: generating, from the received acoustic signal, audio data comprising one or more features of the acoustic source, forming combined data representative of the neural data and the audio data, and providing the combined data to a classification network configured to calculate a similarity score between the neural data and the acoustic source using one or more similarity metrics; and using the similarity scores calculated for each of the acoustic sources to identify, from the plurality of acoustic sources, an acoustic source associated with the listener's auditory attention.

Abstract: A method of forming a structural honeycomb includes cutting and folding a substrate sheet according to predetermined cutting and folding patterns and fold angles that cause the sheet to form a honeycomb having cells that each have at least one face abutting, or nearly abutting, the face of another cell. The honeycomb is then stabilized by joining abutting, or nearly abutting, faces to hold the honeycomb together. The honeycomb may have a prespecified three-dimensional shape. The folding pattern may include corrugation, canted corrugation, or zig-zag folds. Joining may employ fixed and/or reversible joinery, including slotted cross section, tabbed strip, angled strip, integral skin, sewn, or laced. At least some folds may be partially-closed to create bends and twists in the honeycomb structure. Some surfaces of the honeycomb may be covered with a skin or face sheet. The substrate sheet may have flexible electronic traces.

Abstract: Some aspects of this invention provide reagents and methods for the sensitive, quantitative and simultaneous detection of target analytes in complex biological samples by liquid chromatography tandem mass spectrometry (LC MS/MS). Some aspects of this invention provide affinity reagents encoded with mass reporters for the sensitive and quantitative translation of an analyte of interest into a mass tag. The reagents and methods provided herein have general utility in analyte detection and encoding, for example, in biomolecular profiling, molecular diagnostics, and biochemical encoding.