Abstract: Systems and methods provide containers instantiated for each user equipment (UE), or on “per-UE” bases, which consolidate certain network functions for processing UE traffic into an efficient, in-network, and proximate virtualization to reduce latency and increase customizability.

Abstract: A method for detecting an abnormality in a flow system includes obtaining, with a processor, input flow data for the flow system over a series of time intervals, sequentially processing, with the processor, the input flow data to generate, for each time interval in the series of time intervals, flow feature data, the flow feature data being representative of a plurality of flow parameters for the input flow data at the time interval in the series of time intervals, applying, with the processor, the flow feature data to a machine learning tool, the machine learning tool being configured to provide an assessment, for each time interval in the series of time intervals, of whether the input flow data is indicative of the abnormality being present in a following time interval in the series of time intervals, and providing, with the processor, output data indicative of the assessment.

Abstract: An apparatus is described for measuring hemodynamic or metabolic function of an organ or tissue region of a subject comprising a super-continuum laser operating in the near or short-wave infrared wavelength range and comprising a multi-stage amplifier. A source fiber delivers the super-continuum emission to the organ or tissue region, and a collection fiber receives reflected emission from the region. A detector followed by a processor is used to determine a metabolic state and an oxygenation state of the organ or tissue region. A signal-to-noise ratio of the signal is improved using a dual-arm differential measurement technique.

Abstract: A durable solid and liquid repellant nanocomposite material is provided that includes a polymeric matrix comprising polyurethane or fluoropolyurethane that has a plurality of lubricating domains distributed therein. The lubricating domains are formed by a partial crosslinking reaction between a reactive oil comprising a first reactive group selected from the group consisting of: hydroxyl, amine, carboxylic acid, and combinations and a second reactive functional group selected from the group consisting of: isocyanate, hydroxyl, and combinations thereof on a polymeric precursor of the polymeric matrix. The nanocomposite material further includes a plurality of nanoparticles comprising silicon dioxide (SiO2) distributed in the polymeric matrix. At least a portion of the plurality of nanoparticles are bonded to the polymeric matrix. Methods for forming the durable solid and liquid repellant material are also provided.

Abstract: A method is presented for generating an ion beam. The method includes: positioning atoms in a cavity of an optical resonator that defines an optical dipole trap; exciting the atoms while the atoms are trapped in the optical dipole trap using two or more laser beams, thereby forming ions; and driving the ions along an output axis towards a target by applying an electric field to the ions. In one aspect, the ion density of the ion source is regulated, for example using feedback control. Changing the ion density may be achieved, for example by inputting the atomic excitation spectrum into a feedback loop and controlling the power of the two or more laser beams using feedback from the feedback loop.

Abstract: A low-power standard-compliant NB-IoT wake-up receiver (WRX) is presented. The WRX is designed as a companion radio to a full NB-IoT receiver, only operating during discontinuous RX modes (DRX and eDRX), which allows the full high-power radio to turn off while the wake-up receiver efficiently receives NB-IoTWake-Up Signals (WUS). The fabricated receiver achieves 2.1 mW power at ?109 dBm sensitivity with 180 kHz bandwidth over the 750-960 MHz bands. The WRX is fabricated in 28 nm CMOS and consumes 5× less power than the best previously published traditional NB-IoT receivers. This disclosure is the first designed dedicated wake-up receiver for the NB-IoT protocol and demonstrates the benefits of utilizing a WRX to reduce power consumption of NB-IoT radios.

Abstract: In various aspects, the present disclosure provides photodetector devices that may be provided in arrays. The photodetector includes a first electrode, a second electrode, and a photoactive layer assembly disposed therebetween. The photoactive layer assembly comprises a first charge transport layer, a second charge transport layer, and an amorphous silicon (a-Si) material substantially free of doping and being substantially free of doping disposed between the first charge transport layer and the second charge transport layer. The photodetector device transmits light in a predetermined range of wavelengths and is capable of generating detectable photocurrent when light having a light intensity of less than or equal to about 50 Lux is directed towards the photodetector device.

Abstract: A handheld cryoanesthesia or analgesia device for cooling a target area on cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone having an elongated body and a thermoelectric cooling system disposed within the elongated body. The thermoelectric cooling system is configured to physically contact and thermally couple the target area of the cutaneous membranes, mucous membranes, and tissue of the mucocutaneous zone to induce cryoanesthesia or analgesia. The thermoelectric cooling system includes a thermally-conductive cold tip, a thermally-conductive cooling power concentrator thermally coupled to the cold tip, at least one Peltier unit module thermally coupled to the cooling power concentrator, a heatsink thermally coupled to at least one Peltier unit module, a power source, at least one thermal sensor, and a controller operably outputting a control signal to the Peltier unit module to maintain a predetermined temperature.

Abstract: The present invention provides compositions comprising emulsion adjuvant and one or more active agents or substances formulated for infusion or injection into a subject (e.g., using a syringe and needle), as well as methods of formulating and using the same (e.g., as an injectable medicinal composition (e.g., a vaccine)). The emulsion adjuvant of an immunogenic composition of the invention in its preferred form comprises a cationic lipid containing a polar head group and a hydrophobic component (e.g., a dual chain hydrophobic group (e.g., the cationic surfactant dioctadecyl dimethyl ammonium chloride (DODAC) and dioctadecyl dimethyl ammonium bromine (DODAB))). Compositions of the invention comprising emulsion adjuvant and one or more active agents or substances formulated for administration via injection to a subject find use in treatment and/or prevention of infectious disease, cancer and/or allergy.

Abstract: A device for wound irrigation and debridement includes a body extending along a longitudinal axis. The body comprises an interior region and an opening such that that the interior region and the first opening are configured to transfer an irrigation fluid. The body comprises a compliant region having a first stiffness and a debridement region having a different second stiffness. The compliant region defines a distal surface. In a first configuration, the compliant region defines a first axial dimension, the distal surface engages a target body region, and the debridement region is axially offset from the distal surface and disengaged from the target body region. In a second configuration, the compliant region is compressed to define a second axial dimension less than the first axial dimension, thereby engaging the debridement region with the target body region, and the distal surface engages the target body region.

Abstract: The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair.

Abstract: A data processing apparatus includes obtain circuitry that obtains a stream of instructions. The stream of instructions includes a barrier creation instruction and a barrier inhibition instruction. Track circuitry orders sending each instruction in the stream of instructions to processing circuitry based on one or more dependencies. The track circuitry is responsive to the barrier creation instruction to cause the one or more dependencies to include one or more barrier dependencies in which pre-barrier instructions, occurring before the barrier creation instruction in the stream, are sent before post-barrier instructions, occurring after the barrier creation instruction in the stream, are sent. The track circuitry is also responsive to the barrier inhibition instruction to relax the barrier dependencies to permit post-inhibition instructions, occurring after the barrier inhibition instruction in the stream, to be sent before the pre-barrier instructions.

Abstract: In Multi-Policy Decision-Making (MPDM), many computationally-expensive forward simulations are performed in order to predict the performance of a set of candidate policies. In risk-aware formulations of MPDM, only the worst outcomes affect the decision making process, and efficiently finding these influential outcomes becomes the core challenge. Recently, stochastic gradient optimization algorithms, using a heuristic function, were shown to be significantly superior to random sampling. In this disclosure, it was shown that accurate gradients can be computed-even through a complex forward simulation—using approaches similar to those in dep networks. The proposed approach finds influential outcomes more reliably, and is faster than earlier methods, allowing one to evaluate more policies while simultaneously eliminating the need to design an easily-differentiable heuristic function.

Abstract: A dynamic balloon angioplasty system for applying a dynamic pressure to fracture hardened materials embedded within an elastic conduit. The system having a pressure source system outputting at least a first predetermined pressure from a pressure source outlet, and an angioplasty unit fluidly coupled to the pressure source outlet receiving at least the first predetermined pressure. The angioplasty unit having an angioplasty inflation device, an angioplasty balloon connector, and an oscillating mechanism selectively actuated to output a plurality of pressure pulses to the angioplasty balloon via a fluid communication path. A control system is configured to determine an optimal hydraulic pressure oscillation frequency and amplitude for a given procedure and output a control signal to the oscillating mechanism, and monitor a pressure signal to detect fracture of the hardened material within the elastic conduit or system failure or leakage.

Abstract: A nasal tissue implant for reconstruction and tissue engineering of nasal tissue in a subject includes a tissue scaffold component comprising a biocompatible polymeric material having a plurality of open pores configured to support cell growth. The tissue scaffold component conforms to a portion of the subject's nasal region and defines at least a portion of the subject's nasal anatomy. A method of making an implantable nasal tissue implant for reconstructing a portion of a nasal anatomy of a human or other animal subject is also provided that includes laser sintering or three-dimensional (3D) printing a biocompatible polymeric material to form a tissue scaffold component comprising a biocompatible polymeric material having a plurality of open pores configured to support cell growth. Again, the tissue scaffold component substantially conforms to a nasal region specific to the human or other animal subject.

Abstract: Materials and methods are provided for treatment and/or prevention of Staphylococcal diseases and disorders such as infection and dermal inflammation.

Abstract: Methods, apparatuses and systems provide technology for a high frequency alternating-current (HFAC) distribution network for a vehicle that includes a plurality of HFAC zones coupled to a direct-current (DC) power source, the plurality of HFAC zones disbursed within the vehicle, where each HFAC zone includes a HFAC resonant inverter to convert DC power to HFAC power and a HFAC bus coupled to the HFAC resonant inverter, the HFAC bus to distribute the HFAC power to one or more loads. The technology includes a CLCL resonant tank circuit having two capacitors and two inductors, a push-pull circuit coupled to the CLCL resonant tank circuit, the push-pull circuit including a pair of switches, and a transformer to couple the inverter to the HFAC bus.

Abstract: A domain adaptive systolic-array-processor is presented with 256 programmable cores in a 12 nm CMOS for wireless communication workloads. The domain adaptive processor uses a globally homogeneous but locally heterogeneous architecture, decode-less reconfiguration instructions for data streaming, single-cycle data communication between functional units (FUs), and lightweight nested-loop control. This disclosure shows how configuration flexibility and fast program loading allows a wide range of communication workloads to be mapped and swapped in sub-?s, supporting continually evolving communication standards such as 5G. The domain adaptive processor achieves 507 GMACs/J and a peak performance of 264 GMACs.

Abstract: A printer having: an ink nozzle; an extractor laterally spaced from the ink nozzle; a plurality of gas nozzles arranged around the ink nozzle; and three modes of operation, including an electrohydrodynamic mode, an aerodynamic mode, and a combined mode. The modes operate as follows: a voltage is applied across the ink nozzle and the extractor in the electrohydrodynamic mode; a jet of gas is discharged from each of the gas nozzles in the aerodynamic mode; and the voltage is applied and the jets of gas are discharged in the combined mode.

Abstract: Beam steering device such as optical phased array (OPA) is a key component in applications of solid-state LIDAR and wireless communication. The traditional single-layer OPA results in a significant energy loss due to the substrate leakage caused by the downward coupling from the grating coupler structure. In the present disclosure, we have investigated a structure based on multi-layers Si3N4/SiO2 platform that can form a 3D OPA to emit the light from the edge of the device with a high efficiency, a 2D converged out-coupling beam will be end-fired to the air. The high efficiency and wide horizontal beam steering are demonstrated numerically, the influence of vertical crosstalk, the delay length, number of waveguide layers, and the fabrication feasibility are also discussed.