Abstract: A transvaginal stimulation device comprises a probe body sized to fit entirely within a vaginal cavity of a female patient. The probe body has a stimulating side defined by a length and a width of the probe body. The transvaginal stimulation device further comprises a pair of electrodes disposed on the stimulating side of the probe body and laterally spaced from each other. A method for treating stress urinary incontinence in a female patient comprises inserting the intravaginal device into a vaginal cavity of the female patient, positioning the pair of electrodes against an anterior wall of the vagina of the female patient, and conveying stimulation energy between the pair of electrodes to stimulate at least one muscle of a urethral sphincter muscle of the female patient without substantially stimulating pelvic floor muscles of the female patient.

Abstract: Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change.

Abstract: A method is disclosed for suppressing propagation of a metal in a solid state electrolyte during cycling of an electrochemical device including the solid state electrolyte and an electrode comprising the metal. One method comprises forming the solid state electrolyte such that the solid state electrolyte has a structure comprising a plurality of grains of a metal-ion conductive material and a grain boundary phase located at some or all of grain boundaries between the grains, wherein the grain boundary phase suppresses propagation of the metal in the solid state electrolyte during cycling. Another method comprises forming the solid state electrolyte such that the solid state electrolyte is a single crystal.

Abstract: A method of directly joining a polymer to a metal along a joint interface through the formation of C—O-M chemical bonds, where M represents an element in the metal to be joined. The method includes heating the metal to a predetermined temperature above a glass transition temperature of the polymer and less than a flash ignition temperature of the polymer and less than a metal melting temperature of the metal; and applying force to the joint interface of the metal and the polymer to generate intimate atomic contact between the metal and the polymer to create C—O-M chemical bonds between the metal and the polymer.

Abstract: A system for predicting aggressive driving behavior for a driver of a vehicle includes a first edge computing device that can acquire spatial-temporal data for the vehicle from one or more sensors that are part of traffic infrastructure. The first edge computing device includes a processor and instructions executable by the processor that execute deep learning methods on the data from the sensors to cluster the data as a driving score. A trained model is applied to the driving score to determine an aggressive driving behavior risk level, and the first edge computing device is configured to predict the aggressive driving behavior based on the aggressive driving behavior risk level.

Abstract: The present invention relates to methods and biomarkers for detection and characterization of conditions associated with aberrant function of the PPP2R1A subunit of the PP2A protein (e.g., high grade subtypes of uterine cancer) in biological samples (e.g., tissue samples, blood samples, plasma samples, cell samples, serum samples), and related methods of treatment. In particular, the present invention provides compositions and methods for characterizing a patient as having such a condition by identifying mutations in the PPP2R1A subunit of the PP2A gene or gene products, and related methods of treatment through administering to such a patient a DNA Damage Response Pathway (DDR) modulating agent (e.g., a ribonucleotide reductase inhibitor).

Abstract: A material having a chrome-like appearance includes a substrate and a multilayer stack with at least three material layers, each is independently selected from the group consisting of: germanium (Ge), titanium oxide (TiO2), silicon dioxide (SiO2), titanium (Ti), nickel (Ni), aluminum (Al), aluminum oxide (Al2O3), silver (Ag), gold (Au), magnesium fluoride (MgF2), magnesium oxide (MgO), silicon (Si), silicon oxide (SiO2), silicon carbide (SiC), tungsten (W), hafnium oxide (HfO2), zinc (Zn), zinc oxide (ZnO), zinc sulfide (ZnS), zinc selenide (ZnSe), chalcogenides, iron oxide (Fe2O3) and combinations thereof. The material is free of chromium (Cr) and displays a specular reflectivity such that ? about 70% of wavelengths in a visible light range of 390 to 750 nm are reflected without scattering. In certain variations, a radiofrequency (RF)-transparent material having a chrome-like appearance is free of any metals. Methods of making the materials having the chrome-like appearance are also provided.

Abstract: A dependent closed pressure vessel is fluidly coupled to an independent closed pressure vessel. A pressure sensor monitors pressure in the vessels to generate raw pressure measurement data. A flow meter monitors multidirectional rate of flow of fluid between the vessels and the volume of fluid flowing from the independent closed pressure vessel to generate raw rate of flow and raw volume measurement data. A pressure/flow regulator valve adjusts pressure in the dependent closed pressure vessel in response to a pressure set point signal generated in response to the raw pressure data, adjusts the rate of flow of fluid between the vessels in response to a rate of flow set point signal generated in response to the raw rate of flow data, and adjusts the rate of flow of fluid between the vessels in response to a volume set point signal generated in response to the raw volume data.

Abstract: A system for detecting and preventing, in real time, malicious broadcasting messages from an electronic control module attempting to attack a vehicle network is disclosed. The system includes electronic control modules in communication via a serial data link of the vehicle network. At least one electronic control module is configured to receive at least a portion of a serial message on the vehicle network transmitted by another electronic control module, identify the serial message as malicious based on the received portion of the serial message, and in response to identifying the serial message as malicious, inject a dominant bit into the serial message for the vehicle network to cause an error frame in the serial message. Other example systems and methods for detecting and preventing, in real time, malicious broadcasting messages are also disclosed.

Abstract: A method includes inputting a source into a weighted and undirected graph having a plurality of nodes and edges, inputting a target, inputting a plurality of objectives, searching the graph using a rapidly exploring random tree algorithm to determine a solution path that meets an existence constraint and an order constraint, determining a plurality of paths between the source and the target that intersects with each one of the plurality of objectives at least once that conforms with the existence constraint, assigning a travel cost for each of the determined plurality of paths, determining a visiting order of the plurality of objectives that reduces the assigned travel cost by the RRT* algorithm asymptotically decreasing with an allocated computation time by rewiring each one of the plurality of objectives and outputting the solution path to form a connected graph having the plurality of nodes.

Abstract: A method and system for performing online adapted radiotherapy are provided using combined ultrasound and ionizing radiation induced acoustic imaging (iRAI) computed tomography imaging techniques that can be used for measurement of low to ultrahigh dose deliveries (>40 Gy/s). Multiplexed transducers detect US and iRAI signals allowing for anatomical/functional imaging and radiation mapping with absolute dosimetry measurements of a region of interest during a radiotherapy session. Corrections to radiation dosage intensities and locations is determined and provided as feedback to a radiation source to improve the accuracy of applied radiation dosages intra- or inter-radiotherapy treatment sessions preventing the irradiation of healthy tissues and ensuring the accurate delivery of radiation to a tumor or region of interest.

Abstract: A computer-implemented method is presented for scanning a computer network. The method includes: a) sending a particular network probe to a network address in a computer network; b) receiving a response to the network probe from the network address; c) appending the response to a set of features forming a feature vector; d) determining a next network probe to conduct at the network address; and e) predicting, by the computer processor, the response from the next network probe using the feature vector and a model, where the model is trained using a machine learning method and outputs a probability that a given network address will respond to a network probe.

Abstract: A system for sharing sensor data between a vehicle and a plurality of remote system generally includes a vehicle communication system, a three-dimensional (3D) sensor, and a controller. The controller is programmed to generate an initial 3D point cloud using the 3D sensor, generate an occupancy grid map based on the initial 3D point cloud, and select a producer remote system to provide data for a cell of the occupancy grid map classified as a first blindspot. The controller is further programmed to send a data request to the producer remote system using the vehicle communication system, receive data from the producer remote system including information about the cell of the occupancy grid map classified as the first blindspot, generate a merged 3D point cloud by merging the data received from the producer remote system with the initial 3D point cloud, and identify objects using the merged 3D point cloud.

Abstract: A method for detecting an abnormality in a flow system includes obtaining, with a processor, input flow data for the flow system over a series of time intervals, sequentially processing, with the processor, the input flow data to generate, for each time interval in the series of time intervals, flow feature data, the flow feature data being representative of a plurality of flow parameters for the input flow data at the time interval in the series of time intervals, applying, with the processor, the flow feature data to a machine learning tool, the machine learning tool being configured to provide an assessment, for each time interval in the series of time intervals, of whether the input flow data is indicative of the abnormality being present in a following time interval in the series of time intervals, and providing, with the processor, output data indicative of the assessment.

Abstract: Systems and methods provide containers instantiated for each user equipment (UE), or on “per-UE” bases, which consolidate certain network functions for processing UE traffic into an efficient, in-network, and proximate virtualization to reduce latency and increase customizability.

Abstract: An apparatus is described for measuring hemodynamic or metabolic function of an organ or tissue region of a subject comprising a super-continuum laser operating in the near or short-wave infrared wavelength range and comprising a multi-stage amplifier. A source fiber delivers the super-continuum emission to the organ or tissue region, and a collection fiber receives reflected emission from the region. A detector followed by a processor is used to determine a metabolic state and an oxygenation state of the organ or tissue region. A signal-to-noise ratio of the signal is improved using a dual-arm differential measurement technique.

Abstract: A method is presented for generating an ion beam. The method includes: positioning atoms in a cavity of an optical resonator that defines an optical dipole trap; exciting the atoms while the atoms are trapped in the optical dipole trap using two or more laser beams, thereby forming ions; and driving the ions along an output axis towards a target by applying an electric field to the ions. In one aspect, the ion density of the ion source is regulated, for example using feedback control. Changing the ion density may be achieved, for example by inputting the atomic excitation spectrum into a feedback loop and controlling the power of the two or more laser beams using feedback from the feedback loop.

Abstract: A durable solid and liquid repellant nanocomposite material is provided that includes a polymeric matrix comprising polyurethane or fluoropolyurethane that has a plurality of lubricating domains distributed therein. The lubricating domains are formed by a partial crosslinking reaction between a reactive oil comprising a first reactive group selected from the group consisting of: hydroxyl, amine, carboxylic acid, and combinations and a second reactive functional group selected from the group consisting of: isocyanate, hydroxyl, and combinations thereof on a polymeric precursor of the polymeric matrix. The nanocomposite material further includes a plurality of nanoparticles comprising silicon dioxide (SiO2) distributed in the polymeric matrix. At least a portion of the plurality of nanoparticles are bonded to the polymeric matrix. Methods for forming the durable solid and liquid repellant material are also provided.

Abstract: In various aspects, the present disclosure provides photodetector devices that may be provided in arrays. The photodetector includes a first electrode, a second electrode, and a photoactive layer assembly disposed therebetween. The photoactive layer assembly comprises a first charge transport layer, a second charge transport layer, and an amorphous silicon (a-Si) material substantially free of doping and being substantially free of doping disposed between the first charge transport layer and the second charge transport layer. The photodetector device transmits light in a predetermined range of wavelengths and is capable of generating detectable photocurrent when light having a light intensity of less than or equal to about 50 Lux is directed towards the photodetector device.

Abstract: A low-power standard-compliant NB-IoT wake-up receiver (WRX) is presented. The WRX is designed as a companion radio to a full NB-IoT receiver, only operating during discontinuous RX modes (DRX and eDRX), which allows the full high-power radio to turn off while the wake-up receiver efficiently receives NB-IoTWake-Up Signals (WUS). The fabricated receiver achieves 2.1 mW power at ?109 dBm sensitivity with 180 kHz bandwidth over the 750-960 MHz bands. The WRX is fabricated in 28 nm CMOS and consumes 5× less power than the best previously published traditional NB-IoT receivers. This disclosure is the first designed dedicated wake-up receiver for the NB-IoT protocol and demonstrates the benefits of utilizing a WRX to reduce power consumption of NB-IoT radios.