Patents Assigned to The State University
  • Strawberry plant named 'NJ08-08-6'
    Publication number: 20150289430
    Abstract: A new and distinct cultivar of strawberry plant (Fragaria×annanassa), was developed from seed produced by a hand pollinated cross between ‘NJ01-73-3’ and ‘NJ03-232-2’. The new strawberry plant named ‘NJ08-08-6’ is distinguished by its highly vigorous, upright growth habit, high productivity, excellent fruit quality and exquisite flavor.
    Type: Application
    Filed: April 4, 2014
    Publication date: October 8, 2015
    Applicant: Rutgers, The State University
    Inventors: Gojko J. Jelenkovic, Peter J. Nitzsche, William T. Hlubik, Jessica D. Baculis
  • USE OF COLLAGENASE TO TREAT GLAUCOMA
    Publication number: 20150273028
    Abstract: Provided is a method of treatment for reducing fibrosis involving administering purified collagenase into an anterior chamber of an eye of a human patient.
    Type: Application
    Filed: October 24, 2013
    Publication date: October 1, 2015
    Applicant: The Research Foundation for The State University of New York
    Inventor: Robert Honkanen
  • Polyesters and methods of use thereof
    Patent number: 9144579
    Abstract: The invention provides polymers and methods for the treatment of pain and inflammation.
    Type: Grant
    Filed: August 19, 2013
    Date of Patent: September 29, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Kathryn E. Uhrich, Roselin Rosario-Melendez
  • In Situ Exfoliation Method to Fabricate a Graphene-Reinforced Polymer Matrix Composite (G-PMC)
    Publication number: 20150267030
    Abstract: A method for forming a graphene -reinforced polymer matrix composite is disclosed. The method includes distributing graphite microparticles into a molten thermoplastic polymer phase; and applying a succession of shear strain events to the molten polymer phase so that the molten polymer phase exfoliates the graphite successively with each event until at least 50% of the graphite is exfoliated to form a distribution in the molten polymer phase of single- and multi-layer graphene nanoparticles less than 50 nanometers thick along the c-axis direction.
    Type: Application
    Filed: March 14, 2013
    Publication date: September 24, 2015
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Thomas Nosker, Jennifer Lynch, Justin Hendrix, Bernard Kear, Gordon Chiu, Stephen Tse
  • Compositions and methods for preparing recombinant MG53 and methods for optimizing same
    Patent number: 9139630
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. In particular, the present invention provides nucleic acid molecules that include optimization features that enhance the expression and/or recovery and/or activity of encoded polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: September 22, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Jianjie Ma, Noah Weisleder, Chuanxi Cai
  • Oral compositions comprising a zinc compound and an anti-microbial agent
    Patent number: 9138428
    Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: September 22, 2015
    Assignee: The Research Foundation For The State University of New York
    Inventors: Marvin Cohen, Susanne Cohen, Robert G. Flynn
  • Antibacterial agents: high-potency myxopyronin derivatives
    Patent number: 9133155
    Abstract: The invention provides compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Ya, Yb, R1, R2, and G are as described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as inhibitors of bacterial RNA polymerase and as antibacterial agents.
    Type: Grant
    Filed: September 16, 2011
    Date of Patent: September 15, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Richard H. Ebright, Yon W. Ebright
  • System and method for acoustic detection of coronary artery disease and automated editing of heart sound data
    Patent number: 9125574
    Abstract: Systems and methods for acoustic detection of coronary artery disease (CAD) and automated editing of heart sound data are provided.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: September 8, 2015
    Assignee: Rutgers, The State University
    Inventors: Mohammad Zia, Benjamin Griffel, John Semmlow
  • Compositions and vaccines against influenza A and influenza B infections
    Patent number: 9119810
    Abstract: Novel models of interactions of the Nonstructural Protein of influenza A and influenza B viruses (NS1A and NS1B, respectively) with dsRNA are presented. On the basis of the models, novel recombinant viruses and vaccines against influenza A and influenza B viruses are provided.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: September 1, 2015
    Assignees: Rutgers, The State University of New Jersey
    Inventors: Gaetano T. Montelione, Robert M. Krug, Yin Cuifeng, Ma Lichung
  • TITANATE AND TITANIA NANOSTRUCTURES AND NANOSTRUCTURE ASSEMBLIES, AND METHODS OF MAKING SAME
    Publication number: 20150239748
    Abstract: The invention relates to nanomaterials and assemblies including, a micrometer-scale spherical aggregate comprising: a plurality of one-dimensional nanostructures comprising titanium and oxygen, wherein the one-dimensional nanostructures radiate from a hollow central core thereby forming a spherical aggregate.
    Type: Application
    Filed: April 29, 2013
    Publication date: August 27, 2015
    Applicant: The Research Foundation for The State University of New York
    Inventors: Stanislaus S. Wong, Yuanbing Mao
  • Semiconductor devices including polar insulation layer capped by non-polar insulation layer
    Patent number: 9117817
    Abstract: Illustrative embodiments of semiconductor devices including a polar insulation layer capped by a non-polar insulation layer, and methods of fabrication of such semiconductor devices, are disclosed. In at least one illustrative embodiment, a semiconductor device may comprise a semiconductor substrate, a polar insulation layer disposed on the semiconductor substrate and comprising a Group V element configured to increase a carrier mobility in at least a portion of the semiconductor substrate, and a non-polar insulation layer disposed above the polar insulation layer.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: August 25, 2015
    Assignees: Auburn University, Rutgers, The State University of New Jersey
    Inventors: John R. Williams, Ayayi C. Ahyi, Tamara F. Isaacs-Smith, Yogesh K. Sharma, Leonard C. Feldman
  • COPPER FLUORIDE BASED NANOCOMPOSITES AS ELECTRODE MATERIALS
    Publication number: 20150236341
    Abstract: The present invention relates to primary and secondary electrochemical energy storage systems, particularly to such systems as battery cells, which use materials that take up and release ions as a means of storing and supplying electrical energy.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 20, 2015
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Glenn Amatucci, Fadwa Badway
  • High-throughput biomarker segmentation utilizing hierarchical normalized cuts
    Patent number: 9111179
    Abstract: A method and apparatus for obtaining segmented images of the stained regions may comprise quantifying the extent of the presence of staining of a biomarker in an original image of a sample, which may comprise selecting a domain swatch of data based upon a user specified domain knowledge; clustering the data within the original image by conducting a frequency weighted mean shift of the data within the original image to convergence, forming a hierarchical plurality of layers each having a different data resolution to form a hierarchical data pyramid; segmenting the plurality of mean shifted data images to determine in each mean shifted data image within the hierarchical data pyramid data not excluded as outside of the swatch; mapping the data not excluded as outside the swatch spatially back to the original image to create a final image; and, storing the final image on a storage medium for further analysis.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: August 18, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Andrew Janowczyk, Sharat Chandran, Anant Madabhushi
  • NOVEL PRODRUGS FOR SELECTIVE ANTICANCER THERAPY
    Publication number: 20150224208
    Abstract: The present invention provides a compound having the structure: wherein X is a therapeutic agent containing at least one amine nitogen and the amine nitrogen on the therapeutic agent covalently bonds directly to carbon ?; Z is CH3 or CF3; R1 is —H, —NR2R3, —NH—C(?O)—R4, —NH—C(?O)—OR4, —CH2—C(?O)—NR5R6, —OR7, —CO2R7, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl, or heteroaryl, wherein R2, R3, R4, R5, R6 and R7 are each, independently, —H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, heteroalkyl, cycloalkyl, heterocyclyl, aryl, alkylaryl, heteroaryl, alkylheteroaryl, an amino acid or an oligopeptide; wherein an amine of the amino acid or oligopeptide is substituted or unsubstituted; and n is an integer from 0 to 6; or a diastereomer, enantiomer or pharmaceutically acceptable salt of the compound.
    Type: Application
    Filed: September 18, 2013
    Publication date: August 13, 2015
    Applicant: The Research Foundation for The State University of New York
    Inventors: Nobuhide Ueki, Michael J. Hayman
  • Antimicrobial agents
    Patent number: 9102617
    Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R3-R8 and X and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: August 11, 2015
    Assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New Jersey
    Inventors: Edmond J. Lavoie, Ajit Parhi, Daniel S. Pilch
  • Apricot tree named 'NJA152'
    Publication number: 20150223377
    Abstract: A new and distinct apricot variety of Prunus armeniaca named ‘NJA152’ is provided. This variety is distinguished from other apricot varieties by its unique combination of a slightly later blooming habit, good production of glossy glabrous fruit with a red blush over a yellow-orange ground color, freestone flesh which has a melting texture and is moderately juicy, and flavor that is sweet-tart and aromatic.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 6, 2015
    Applicant: Rutgers, The State University
    Inventors: Joseph C. Goffreda, Anna M. Voordeckers
  • Systems and methods for capture and sequestration of gases and compositions derived therefrom
    Patent number: 9095815
    Abstract: A composition is produced by a hydrothermal liquid phase sintering process, and the process includes providing a porous matrix, the porous matrix having a shape, and allowing a component of the porous matrix to undergo a reaction with an infiltrating medium to form a first product, the infiltrating medium including a greenhouse gas, a remainder of the porous matrix acting as a scaffold for facilitating the formation of the first product. The composition includes the first product and the reminder of the porous matrix. The composition has a microstructure that resembles a net-like interconnecting network. The composition maintains the shape of the porous matrix. The composition is free of hydraulic bonds.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: August 4, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Richard E. Riman, Vahit Atakan
  • Use of lecithin:retinol acyl transferase gene promoter methylation in evaluating the cancer state of subject
    Patent number: 9090941
    Abstract: The present invention relates to a method of evaluating the cancer state of a subject using lecithin:retinol acyl transferase (LRAT) gene promoter methylation status. Methods of analyzing and quantifying LRAT gene promoter methylation level are also disclosed. The present invention also relates to methods of determining the prognosis for s subject having cancer by assessing LRAT mRNA expression and LRAT protein expression. Methods of cancer detection, diagnosis, prognosis, and treatment are also disclosed.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: July 28, 2015
    Assignees: Cornell Research Foundation, Inc., Sloan Kettering Institute for Cancer Research, Rutgers, The State University of New Jersey
    Inventors: Francis Barany, Yu-Wei Cheng, Philip Paty, Daniel Notterman
  • Biotinylated compounds
    Patent number: 9090646
    Abstract: The invention provides new biotinylated compounds and methods for their use.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: July 28, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Roger A. Jones, Barbara L. Gaffney
  • Apricot tree named ‘NJA151’
    Patent number: PP25862
    Abstract: A new and distinct apricot variety of Prunus persica named ‘NJA151’ is provided. This variety is distinguished from other apricot varieties by its unique combination of showy flowers, fruit that ripen in early season, attractive fruit with a dark orange ground color, freestone fruit with a moderately juicy, fine, melting texture and moderately acidic flavor, and good production of fruit.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: September 8, 2015
    Assignee: Rutgers, The State University
    Inventors: Joseph C. Goffreda, Anna M. Voordeckers