Abstract: A multicore fiber includes: a first core having a first propagation loss of a first light beam in a mode one order higher than a mode of a second light beam that transmits information. The first propagation loss is 0.02 dB/m or more and 1 dB/m or less, in a wavelength band of light beams including the second light beam that transmit the information when a bend having a diameter of 280 mm is applied to the multicore fiber.

Abstract: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.

Abstract: Cells and cell cultures are provided that have improved tolerance to 3-hydroxypropionic acid (3HP). Genetic modifications to provide a mutated or overexpressed SFA1 gene or other enhancement of 3HP detoxification via a glutathione-dependent dehydrogenase reaction, including medium supplementation with glutathione, may be combined with a 3HP producing metabolic pathway.

Abstract: A yeast cell having a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has at least one exogenous gene encoding NADP dependent GAPDH and/or has up-regulation of at least one endogenous gene expressing NADP dependent GAPDH, wherein combined expression of the enzymes NADP dependent GAPDH, PDC, ALD, ACS, ACC* and MCR in said host cell increases metabolic flux towards 3-HP via malonyl-CoA compared to an otherwise similar yeast cell lacking said genetic modification.

Abstract: The present disclosure relates to system applications of multicore optical fibers. One embodiment relates to a base transceiver station for a wireless telecommunication system comprising a plurality of antenna units arranged in a MIMO configuration and adapted for transmission and/or reception of radio-frequency signals, an optical transmitter in the form of an electro-optic conversion unit for each of said plurality of antenna units, each electro-optic conversion unit adapted for converting an RF signal into an optical signal, a plurality of a single core optical fibers for guiding the optical signals, and at least one first space division multiplexing (SDM) unit adapted for multiplexing said single core optical fibers into respective individual cores of a multicore fiber, or into respective individual modes of a multimode fiber.

Abstract: A genetically modified Saccharomyces cerevisiae including an active fermentation pathway producing 3-HP expresses an exogenous gene expressing the aminotransferase YhxA from Bacillus cereus AH1272 catalyzing a transamination reaction between beta-alanine and pyruvate to produce malonate semialdehyde. The yeast may also express a 3-hydroxyisobutyrate dehydrogenase (HIBADH) and a 3-hydroxypropanoate dehydrogenase (3-HPDH) and aspartate 1-decarboxylase. Additionally the yeast may express pyruvate carboxylase and aspartate aminotransferase.

Abstract: A method of conducting radiofluorination of a substrate, includes: (a) contacting an aqueous solution of [18F] fluoride with a polymer supported phosphazene base for sufficient time for trapping of [18F] fluoride on the polymer supported phosphazene base; and (b) contacting a solution of the substrate with the polymer supported phosphazene base having [18F] fluoride trapped thereon obtained in step (a) for sufficient time for a radiofluorination reaction to take place.

Abstract: There is provided an encryption device including a data encryption unit configured to conduct encryption on the basis of a white box model in which at least a part of a plurality of round functions for sequentially conducting encryption processing on an input value is tabulated, and input and output values of the round function are recognizable from an outside. The plurality of round functions each have an encryption function that is tabulated and encrypts an input value in a black box model in which input and output values are recognizable from the outside and an intermediate value is not recognizable from the outside.

Abstract: The present invention relates to an all-optical pressure sensor comprising a waveguide accommodating a distributed Bragg reflector. Pressure sensing can then be provided by utilizing effective index modulation of the waveguide and detection of a wavelength shift of light reflected from the Bragg reflector. Sound sensing may also be provided thereby having an all-optical microphone. One embodiment of the invention relates to an optical pressure sensor comprising at least one outer membrane and a waveguide, the waveguide comprising at least one core for confining and guiding light, at least one distributed Bragg reflector located in said at least one core, and at least one inner deflecting element forming at least a part of the core, wherein the pressure sensor is configured such that the geometry and/or dimension of the at least one core is changed when the at least one outer membrane is submitted to pressure.

Abstract: The present invention relates to an all-optical sensor utilizing effective index modulation of a waveguide and detection of a wavelength shift of reflected light and a force sensing system accommodating said optical sensor. One embodiment of the invention relates to a sensor system comprising at least one multimode light source, one or more optical sensors comprising a multimode sensor optical waveguide accommodating a distributed Bragg reflector, at least one transmitting optical waveguide for guiding light from said at least one light source to said one or more multimode sensor optical waveguides, a detector for measuring light reflected from said Bragg reflector in said one or more multimode sensor optical waveguides, and a data processor adapted for analyzing variations in the Bragg wavelength of at least one higher order mode of the reflected light.

Abstract: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.

Abstract: A parallel magnetic refrigerator assembly, includes at least two magnetocaloric stages arranged in parallel connection, each having in use a cold side and a hot side; each magnetocaloric stage including hot and cold side heat exchange circuit for carrying a heat exchange fluid to respectively receive and transfer heat from the magnetocaloric stages; wherein the hot and cold side heat exchange circuit are configured such that in use a heat exchange fluid passes in thermal contact with the respective hot and cold sides of both magnetocaloric stages. The magnetocaloric stages have substantially the same temperature spans but different cold end and hot end temperatures. In this way the device temperature span may be substantially larger than the individual temperature span of each magnetocaloric stage.

Abstract: The present invention is based, in part, on the identification of novel methods for defining predictive biomarkers of response to anti-cancer drugs.

Abstract: The present invention relates to a thin and in principle unsupported solid oxide cell, comprising at least a porous anode layer, an electrolyte layer and a porous cathode layer, wherein the anode layer and the cathode layer comprise an electrolyte material, at least one metal and a catalyst material, and wherein the overall thickness of the thin reversible cell is about 150 ?m or less, and to a method for producing same. The present invention also relates to a thin and in principle unsupported solid oxide cell, comprising at least a porous anode layer, an electrolyte layer and a porous cathode layer, wherein the anode layer and the cathode layer comprise an electrolyte material and a catalyst material, wherein the electrolyte material is doper zirconia, and wherein the overall thickness of the thin reversible cell is about 150 ?m or less, and to a method for producing same.

Abstract: The present invention relates to a system and a method for connecting and/or interfacing a converter, such as a switched mode converter, to an electrical power grid. The invention furthermore relates to control of the converter. The present invention facilitates that the point of common coupling (PCC) between a utility grid and a converter is provided at the converter output. This facilitates that a converter, and thereby an electrical power source, may be connected to an electrical power grid without use of an inductor, such as a reactor.

Abstract: The present invention relates to a filtering apparatus and method for mixing a compound of solid and fluid phases, separating the phases and/or extracting fluid from the compound. One embodiment of the invention discloses a filtering apparatus comprising a first filter section accommodating a first group of filter members, and a second filter section accommodating a second group of filter members, a piping system providing pipelined fluid communication between the filter sections and between a filter section and said filter section's corresponding group of filter members, the piping system configured such that the filter members form filtered fluid openings of the filtering apparatus, and circulation means, such as a pump, configured for passing fluid in a forward flow and/or in a reverse flow between the filter sections. In particular the invention may be used for the mashing process in a beer brewing procedure.

Abstract: The present invention relates to preparation of a polymer coating comprising or consisting of polymer chains comprising or consisting of units of 2-methoxyethyl acrylate synthesized by Surface-Initiated Atom Transfer Radical Polymerization (SI ATRP) such as ARGET SI ATRP or AGET SI ATRP and uses of said polymer coating.

Abstract: A yeast cell having a reduced level of activity of NAD dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has at least one exogenous gene encoding NADP dependent GAPDH and/or has up-regulation of at least one endogenous gene expressing NADP dependent GAPDH, wherein combined expression of the enzymes NADP dependent GAPDH, PDC, ALD, ACS, ACC* and MCR in said host cell increases metabolic flux towards 3-HP via malonyl-CoA compared to an otherwise similar yeast cell lacking said genetic modification.

Abstract: Cells and cell cultures are provided that have improved tolerance to 3-hydroxypropionic acid (3HP). Genetic modifications to provide a mutated or overexpressed SFA1 gene or other enhancement of 3HP detoxification via a glutathione-dependent dehydrogenase reaction, including medium supplementation with glutathione, may be combined with a 3HP producing metabolic pathway.

Abstract: Disclosed is an air distribution control unit or a filtration/ventilation unit which is portable and/or can be mounted on or integrated in furniture e.g. as a cabinet of at the head region of a bed. The filtration/ventilation unit cleanses air from a person/patient by aspirating the person's/patient's exhalation air into the filtration/ventilation unit. To construct an at least partly isolated area around the patient, filtered air can be directed e.g. vertically out of the filtration/ventilation unit to perform an air curtain. Use of the filtration/ventilation unit reduces the risk of dissipation of air-borne diseases and health hazardous matter, and reduces the amount of air to ventilate a room with patients.