Patents Assigned to The Trustees of Indiana University
  • Patent number: 11963789
    Abstract: A feeding analysis system reviews collected feeding data and provides analysis of data regarding nutritive sucking, feeding, and related activity.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: April 23, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Scott Buckley, Neil R. M. Buist, W. Christopher Lang
  • Patent number: 11942317
    Abstract: A method for analyzing charged particles may include generating, in or into an ion source region, charged particles from a sample of particles, causing the charged particles to enter a mass spectrometer from the ion source region at each of a plurality of differing physical and/or chemical conditions in a range of physical and/or chemical conditions in which the sample particles undergo structural changes, controlling the mass spectrometer to measure at least the charge magnitudes of the generated charged particles at each of the plurality of differing physical and/or chemical conditions, determining, with a processor, an average charge magnitude of the generated charged particles at each of the plurality of differing physical and/or chemical conditions based on the measured charge magnitudes, and determining, with the processor, an average charge magnitude profile over the range of physical and/or chemical conditions based on the determined average charge magnitudes.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: March 26, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: David E. Clemmer, Martin F. Jarrold, Tarick J. El-Baba, Corinne A. Lutomski
  • Patent number: 11931356
    Abstract: The invention provides compositions, compounds, formulations, and methods for treating HPV infections including pre-malignant infections and cancer. Compounds that covalently bind to the HPV E6 protein are disclosed.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: March 19, 2024
    Assignees: The Trustees of Indiana University, Kovina Therapeutics, Inc.
    Inventors: Elliot J. Androphy, Samy O. Meroueh, Zhijian Lu
  • Patent number: 11915674
    Abstract: A resonance podium includes a plurality of walls defining a frame of the resonance podium. A top panel is coupled to the plurality of walls to form a top surface that supports a performer playing a musical instrument on the resonance podium. A resonant panel is also coupled to the plurality of walls and isolated from the top panel. The resonant panel is configured to receive a portion of the musical instrument and to project structurally-transmitted vibrations from the musical instrument for acoustical amplification.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: February 27, 2024
    Assignee: The Trustees of Indiana University
    Inventor: David J. Tagg
  • Publication number: 20240054841
    Abstract: A method of using at least one nanoparticle for an anti-counterfeit application including selecting the at least one nanoparticle having a non-spherical configuration; providing the at least one nanoparticle on a substrate; providing a light to the at least one nanoparticle; determining a position of the at least one nanoparticle based on providing the light to the at least one nanoparticle; determining a color of the at least one nanoparticle based on providing the light to the at least one nanoparticle; defining a nanofingerprint based on the position and the color of the at least one nanoparticle; and recognizing the nanofingerprint.
    Type: Application
    Filed: October 8, 2020
    Publication date: February 15, 2024
    Applicant: The Trustees of Indiana University
    Inventors: Sara E. Skrabalak, Alison F. Smith, Joshua D. Smith
  • Patent number: 11888146
    Abstract: Cathode active materials for lithium-ion batteries comprise a hybrid nanocomposite of graphene and copper fluoride. Such cathode active materials are used, together with a polymeric binder material and optionally a conductive additive to form a cathode for a lithium-ion battery. Methods of producing hybrid nanocomposites of graphene and copper fluoride include hydrothermally reacting functionalized graphene, such as graphene oxide, and precursors of copper fluoride, such as aqueous fluorosilicic acid. Such hydrothermal reactions include sequential heating and freeze drying steps to produce a CuF2-graphene nanocomposite.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: January 30, 2024
    Assignee: The Trustees of Indiana University
    Inventor: Jian Xie
  • Patent number: 11877999
    Abstract: Compositions and methods are provided for treating HPV infections including pre-malignant and cancers. Compounds that specifically bind to the HPV E6 protein and inactivate the protein are disclosed.
    Type: Grant
    Filed: September 26, 2022
    Date of Patent: January 23, 2024
    Assignees: THE TRUSTEES OF INDIANA UNIVERSITY, KOVINA THERAPEUTICS, INC
    Inventors: Elliot J. Androphy, Samy Meroueh, Zhijian Lu, Anne Rietz
  • Publication number: 20240013796
    Abstract: A method of encoding a speech signal includes predicting a feature vector of each of a plurality of frames included in the speech signal based on a ground-truth feature vector of a previous frame of each of the plurality of frames, calculating a residual signal corresponding to each of the plurality of frames based on a ground-truth feature vector of each of the plurality of frames and a predicted feature vector of each of the plurality of frames, and generating a bitstring corresponding to each of the plurality of frames by quantizing the residual signal.
    Type: Application
    Filed: September 26, 2023
    Publication date: January 11, 2024
    Applicants: Electronics and Telecommunications Research Institute, The Trustees of Indiana University
    Inventors: Woo-taek LIM, Seung Kwon BEACK, Inseon JANG, Jongmo SUNG, Tae Jin LEE, Byeongho CHO, Minje KIM, Haici YANG
  • Patent number: 11867700
    Abstract: The present disclosure relates to methods of identifying components present in intact lipoprotein particles. Methods provided include single particle mass spectrometry, such as charge detection mass spectrometry (CDMS). Distinct subtypes and subpopulations that exist within lipoprotein density classes are determined based on simultaneously measured m/z and charge of ionized lipoprotein particles.
    Type: Grant
    Filed: April 11, 2023
    Date of Patent: January 9, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Martin F. Jarrold, Corrine A. Lutomski
  • Patent number: 11858889
    Abstract: Disclosed are compounds that can modulate DDAH and the amount of asymmetric dimethylarginine (ADMA) in a subject. Also provided are pharmaceutical compositions comprising these compounds, as well as methods of using these compositions to treat and/or prevent diseases associated with elevated or low levels of DDAH and ADMA.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: January 2, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Jaipal Singh, Kerry Fowler
  • Patent number: 11862448
    Abstract: A CDMS may include an ion source to generate ions from a sample, a mass spectrometer to separate the generated ions as a function of ion mass-to-charge ratio, an electrostatic linear ion trap (ELIT) having a charge detection cylinder disposed between first and second ion mirrors, wherein ions exiting the mass spectrometer are supplied to the ELIT, a charge generator for generating free charges, a field free region between the charge generator and the charge detection cylinder, and a processor configured to control the charge generator, with no ions in the charge detection cylinder, to generate a target number of free charges and cause the target number of free charges to travel across the field-free region and into contact with the charge detection cylinder to deposit the target number of free charges thereon and thereby calibrate or reset the charge detection cylinder to a corresponding target charge level.
    Type: Grant
    Filed: January 4, 2023
    Date of Patent: January 2, 2024
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Martin F. Jarrold, Andrew W. Alexander, Aaron R. Todd
  • Patent number: 11853953
    Abstract: Technologies are disclosed herein for providing an aerial transport network infrastructure for unmanned aerial vehicles, such as drones. The transport network infrastructure comprises models built from publicly available information, such as Federal Communications Commission and Department of Transportation (FCC-DOT) map data. An Electric Regulated Drone Operating System (ERDOS) executing within a drone includes logic for routing, queuing, monitoring, and rescuing using Level 5 automation techniques within the aerial transport network infrastructure.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: December 26, 2023
    Assignee: The Trustees of Indiana University
    Inventor: Aniruddha Banerjee
  • Patent number: 11840681
    Abstract: A gut bioreactor includes a fold region and a flow region. The fold regions include members that cooperate to form crypts. The members may have protuberances extending from a surface of the members into the crypts. The gut bioreactors may include multimaterial fibers that are configured to detect aspects of the crypts or may mechanically move portions of the gut bioreactor.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: December 12, 2023
    Assignee: THE TRUSTEES OF INDIANA UNIVERSITY
    Inventors: Jay T. Lennon, Louis Alexandre van der Elst, Emmi Mueller, Alexander Gumennik
  • Patent number: 11837220
    Abstract: Disclosed is a speech processing apparatus and method using a densely connected hybrid neural network. The speech processing method includes inputting a time domain sample of N*1 dimension for an input speech into a densely connected hybrid network; passing the time domain sample through a plurality of dense blocks in a densely connected hybrid network; reshaping the time domain samples into M subframes by passing the time domain samples through the plurality of dense blocks; inputting the M subframes into gated recurrent unit (GRU) components of N/M-dimension; outputting clean speech from which noise is removed from the input speech by passing the M subframes through GRU components.
    Type: Grant
    Filed: May 5, 2021
    Date of Patent: December 5, 2023
    Assignees: Electronics and Telecommunications Research Institute, The Trustees of Indiana University
    Inventors: Minje Kim, Mi Suk Lee, Seung Kwon Beack, Jongmo Sung, Tae Jin Lee, Jin Soo Choi, Kai Zhen
  • Patent number: 11823402
    Abstract: A method and apparatus for correcting an error in depth information estimated from a two-dimensional (2D) image are disclosed. The method includes diagnosing an error in depth information by inputting a color image and depth information estimated using the color image to a depth error detection network, and determining enhanced depth information by maintaining or correcting the depth information based on the diagnosed error.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: November 21, 2023
    Assignees: Electronics and Telecommunications Research Institute, The Trustees of Indiana University
    Inventors: Soon Heung Jung, Jeongil Seo, Jagpreet Singh Chawla, Nikhil Thakurdesai, David Crandall, Md Reza, Anuj Godase
  • Patent number: 11823688
    Abstract: Disclosed are a method of encoding and decoding an audio signal and an encoder and a decoder performing the method. The method of encoding an audio signal includes identifying an input signal, and generating a bitstring of each encoding layer by applying, to the input signal, an encoding model including a plurality of successive encoding layers that encodes the input signal, in which a current encoding layer among the encoding layers is trained to generate a bitstring of the current encoding layer by encoding an encoded signal which is a signal encoded in a previous encoding layer and quantizing an encoded signal which is a signal encoded in the current encoding layer.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: November 21, 2023
    Assignees: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, The Trustees of Indiana University
    Inventors: Woo-taek Lim, Seung Kwon Beack, Jongmo Sung, Tae Jin Lee, Inseon Jang, Minje Kim
  • Patent number: 11823885
    Abstract: A method for analyzing a sample collected from a surface, the method comprising placing at least a portion of a substrate having a pressure sensitive adhesive layer containing the sample in a holder, adding a spray solvent to the sample-containing pressure sensitive adhesive layer, and analyzing the sample contained in the pressure sensitive adhesive layer and the spray solvent using paper spray mass spectrometry.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: November 21, 2023
    Assignees: The Trustees of Indiana University, The U.S. Government as Represented by the U.S. Army Combat Capabilities Development Command
    Inventors: Nicholas Edward Manicke, William Raymond Anthony Wichert, Ethan M. McBride, Trevor G. Glaros, Phillip M. Mach
  • Publication number: 20230330107
    Abstract: Disclosed are methods to prevent an occurrence of a high-grade serous ovarian cancer and/or breast cancer in a subject by administering a therapeutically effective amount of an antiprogestin to the subject.
    Type: Application
    Filed: August 25, 2021
    Publication date: October 19, 2023
    Applicant: The Trustees of Indiana University
    Inventor: Jaeyeon Kim
  • Patent number: 11790926
    Abstract: A method and apparatus for processing an audio signal are disclosed. According to an example embodiment, a method of processing an audio signal may include acquiring a final audio signal for an initial audio signal using a plurality of neural network models generating output audio signals by encoding and decoding input audio signals, calculating a difference between the initial audio signal and the final audio signal in a time domain, converting the initial audio signal and the final audio signal into Mel-spectra, calculating a difference between the Mel-spectra of the initial audio signal and the final audio signal in a frequency domain, training the plurality of neural network models based on results calculated in the time domain and the frequency domain, and generating a new final audio signal distinguished from the final audio signal from the initial audio signal using the trained neural network models.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: October 17, 2023
    Assignees: Electronics and Telecommunications Research Institute, The Trustees of Indiana University
    Inventors: Mi Suk Lee, Seung Kwon Beack, Jongmo Sung, Tae Jin Lee, Jin Soo Choi, Minje Kim, Kai Zhen
  • Publication number: 20230326051
    Abstract: A method and apparatus for estimating depth information of an image are disclosed. The depth information estimation method of the image includes providing a confidence map for a ground truth depth map; and learning a depth information estimation model for estimating depth information of an image based on the ground truth depth map and the confidence map.
    Type: Application
    Filed: April 7, 2023
    Publication date: October 12, 2023
    Applicants: Electronics and Telecommunications Research Institute, The Trustees of Indiana University
    Inventors: Soon-Heung JUNG, David Crandall, Vibhas Kumar Vats, Shaurya Shubham, Md Alimoor Reza, Chuhua Wang