Patents Assigned to The United States of America, represented by the Secretary,
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Patent number: 10550271Abstract: A method of forming a hydrophobic and oleophobic surface. The method including spin coating an F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane onto an inert surface. The F-POSS has a structure: Each Rf represents a nonreactive, fluorinated organic group, R1 represents a first monovalent organic group comprising at least two carbon atoms, and R2 represents hydrogen or a second monovalent organic group comprising at least two carbon atoms. The F-POSS with 3,3-dichloro-1,1,1,2,2,-pentafluoropropane/1,3-dichloro-1,1,2,2,3-pentafluoropropane are then dried on the inert surface.Type: GrantFiled: September 19, 2017Date of Patent: February 4, 2020Assignee: United States of America as represented by the Secretary of the Air ForceInventors: Timothy S. Haddad, Joseph M. Mabry, Sean Ramirez
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Patent number: 10554015Abstract: A method of making a quasi-phase-matching (QPM) structure comprising the steps of: applying a pattern to a substrate to define a plurality of growth regions and a plurality of voids; growing in a growth chamber a crystalline inorganic material on only the growth regions in the pattern, the crystalline inorganic material having a first polarity; applying an electric field within the growth chamber containing the patterned substrate with the crystalline inorganic material, wherein the electric field reaches throughout the growth chamber; and growing a crystalline organic material having a second polarity in the voids formed in the inorganic material under the influence of the electric field to influence the magnitude and the direction of the second polarity of the crystalline organic material, wherein the second polarity of the crystalline organic material is influenced to be different from the first polarity of the crystalline inorganic material in magnitude and/or direction.Type: GrantFiled: January 25, 2018Date of Patent: February 4, 2020Assignee: United States of America as represented by the Secretary of the Air ForceInventor: Vladimir Tassev
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Patent number: 10553128Abstract: A water rollover simulation system includes a simulation training device. The simulation training device is connected to a track, wherein one end of the track is submerged in water. The simulation training device begins a simulation on another portion of the track not submerged in water, moves toward the end of the track, and completes the simulation by allowing one or more trainees to escape the simulation training device while the simulation training device is submerged under water. The water rollover simulation system includes various safety features. The safety features can be activated automatically after a predetermined amount of time, or manually via a remote control system.Type: GrantFiled: March 15, 2016Date of Patent: February 4, 2020Assignee: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventor: Jack B. Mounts, Jr.
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Patent number: 10553342Abstract: A deformable inductive device includes an elastomer material having at least one deformable electrode and a liquid magnetic core formed in the elastomer material and containing a magnetic liquid. Depending on the device's configuration, the deformable element may be embedded in, attached to, or in close proximity with the liquid magnetic core. In some embodiments, the deformable inductive device may be configured as an inductor, solenoid, or transformer and the deformable electrode is at least partially embedded in the liquid magnetic core, for instance. In another embodiment, the deformable inductive device may be configured as part of a wireless power transfer system which includes a coil and a magnetic backplane having the liquid magnetic core with the coil being attached to or in close proximity to the magnetic backplane.Type: GrantFiled: July 13, 2016Date of Patent: February 4, 2020Assignee: The United States of America as represented by the Secretary of the ArmyInventors: Nathan S. Lazarus, Christopher D. Meyer
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Patent number: 10548987Abstract: The identification and characterization of two fully human CD56-specific monoclonal antibodies targeting spatially separated epitopes proximal and distal to the plasma membrane is described. Also described are antibody-drug conjugates (ADCs) of the identified antibodies and their use for targeting CD56-expressing tumor cells.Type: GrantFiled: July 29, 2016Date of Patent: February 4, 2020Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The Children's Hospital of PhiladelphiaInventors: Dimiter S. Dimitrov, Yang Feng, John M. Maris, Zhongyu Zhu, Robyn Tovah Sussman
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Patent number: 10548970Abstract: Attenuated G9P[6] rotavirus is disclosed herein. In some embodiments, pharmaceutical compositions are disclosed that include an attenuated G9P[6] rotavirus, or a component thereof. These compositions can be used to induce an immune response, such as a protective immune response, to a rotavirus. The compositions can be used as vaccines, such as for children (infants), for example in a prime boost strategy.Type: GrantFiled: September 28, 2016Date of Patent: February 4, 2020Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICESInventors: Baoming Jiang, Yuhuan Wang
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Patent number: 10553897Abstract: A process for making a superionic conducting salt includes: combining a primary salt and an impact member, the primary salt including an ordered phase and being an ionic conductor; impacting the primary salt with the impact member; and converting the primary salt to the superionic conducting salt in response to impacting the primary salt with the impact member at a conversion temperature to make the superionic conducting salt, the conversion temperature optionally being less than a thermally activated transition temperature that thermally converts the primary salt to the superionic conducting salt in an absence of the impacting the primary salt, and the superionic conducting salt including a superionic conductive phase in a solid state at less than the thermally activated transition temperature.Type: GrantFiled: June 3, 2016Date of Patent: February 4, 2020Assignee: GOVERNEMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventor: Terrence John Udovic
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Patent number: 10553090Abstract: A device for signaling including a top member adjacent to a bottom member, a button adjacent to the top member, a sensor adjacent to the top member, a radio adjacent to the top member, a microprocessor board adjacent to the radio, a battery adjacent to the microprocessor board, and a switch adjacent to the bottom member. A button slot and sensor hole formed through the top member. The button is received in the button slot and the sensor in the sensor slot. The microprocessor board further comprises a light emitting diode. The bottom member has a bottom recess and a switch slot. The switch is received in the switch slot. The top member has a sensor recess and a screw hole. The sensor is retained in the sensor recess. The bottom member has a screw recess. The radio, microprocessor board, and battery are slidably received in the bottom slot.Type: GrantFiled: August 23, 2018Date of Patent: February 4, 2020Assignee: United States of America as represented by Secretary of the NavyInventors: Laura C. Tolliver, Peyton B. Cavaroc, Kevin P. Votapka, Robert R. Regal, Lucas D. Powell, Hunter J. Smith
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Patent number: 10551719Abstract: An electro-optical directional coupler is provided having a substrate and a first and second optical waveguide formed on the substrate, where the second waveguide extends adjacent to and parallel with the first waveguide for at least one interaction length. The interaction length has a first end and a second end such that an optical signal applied only to one of the first and second waveguides couples to the other of the first and second waveguides between the ends. A first electrode is proximate the first and second waveguides and between the ends of the interaction length. A first voltage applied to the first electrode independently tunes a coupling of a TE mode. A second electrode located proximate the first and second waveguides and the first electrode and between the ends of the interaction length. A second voltage applied to the second electrode independently tunes a coupling of a TM mode.Type: GrantFiled: February 13, 2017Date of Patent: February 4, 2020Assignee: United States of America as represented by the Secretary of the Air ForceInventors: Richard S Kim, Attila A Szep, Michael L Fanto, Paul M Alsing, Gordon E Lott, Christopher C Tison
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Patent number: 10553093Abstract: A security system to detect motions and/or features associated with a traveler, the security system includes a camera configured to capture an image series of the traveler in an Eulerian or Lagrangian frame of reference, wherein the captured image series contains motions and features associated with the traveler; an alarm system configured to produce an alert signal; and an electronic control unit. The electronic control unit is configured to magnify the motions and features associated with the traveler to generate frame of reference perceptible motions and features, detect characteristic kinematic behaviors of the perceptible motions and features, measure characteristic kinematic quantities of the characteristic kinematic behaviors, determine the presence of features that deviate from a threshold value for the characteristic kinematic quantities, and activate the alarm system to produce the alert signal.Type: GrantFiled: January 29, 2019Date of Patent: February 4, 2020Assignee: The Government of the United States of America, as represented by the Secretary of Homeland SecurityInventors: Mark A. Fry, Barry T. Smith
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Patent number: 10552300Abstract: A process for testing a program includes: receiving a variable comprising a plurality of input values; producing a plurality of equivalence classes for the input values; producing a representative value per equivalence class; producing, by a processor, a primary covering array comprising a plurality of primary vectors; producing a secondary covering array comprising a plurality of secondary vectors; providing the secondary vectors to the program; and producing a result vector comprising a plurality of result entries to test the program. A computer system for testing the program includes: a memory; and a processor, in communication with the memory, wherein the computer system is configured to perform the process for testing the program. A computer program product for testing the program includes: a non-transitory computer readable storage medium readable by a processor and storing program code for execution by the processor to perform the process.Type: GrantFiled: February 9, 2016Date of Patent: February 4, 2020Assignee: UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCEInventors: D. Richard Kuhn, Raghu N. Kacker
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Publication number: 20200029885Abstract: A handheld radio device that incorporates within equipment typically carried by a first-responder but with added functionality which enables assessments of a subject's cognitive, auditory, visual, and speech function. In addition to providing two-way tactical radio functionality, the handheld radio device operates to generate haptic, audible, and visual stimuli, and then assess a subject utilizing the handheld radio device based on the subject's responses to the stimuli on the interfaces and sensors of the handheld radio device. Because this functionality is provided in equipment this is already typically carried by the first-responder, assessments that are more forward-deployed and closer to the point and time of injury, exposure, or period of interest can occur.Type: ApplicationFiled: July 30, 2018Publication date: January 30, 2020Applicant: United States of America as represented by Secretary of the NavyInventor: Matthew A. Yanagi
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Publication number: 20200030261Abstract: This disclosure concerns the discovery of the use of fenoterol analogues for regulating cannabinoid (CB) receptor activity-related disorders and disease, such as dysregulated CB receptors, including treating a disorder or disease, such as a glioblastoma, hepatocellular carcinoma, liver cancer, colon cancer, and/or lung cancer, which is associated with altered cannabinoid receptor activity. In one example, the method includes administering to a subject having or at risk of developing a disorder or disease regulated by CB receptor activity an effective amount of a fenoterol analogue to reduce one or more symptoms associated with the disorder or disease regulated by CB receptor activity.Type: ApplicationFiled: October 11, 2019Publication date: January 30, 2020Applicant: The United States of America, as represented by the Secretary, Department of Health and Human ServicInventors: Irving W. Wainer, Michel Bernier, Rajib K. Paul
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Publication number: 20200030435Abstract: The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines.Type: ApplicationFiled: October 8, 2019Publication date: January 30, 2020Applicants: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, The Government of the United States, as Represented by The Secretary of The ArmyInventors: Alexander G. Pletnev, Joseph R. Putnak, Robert M. Chanock, Brian R. Murphy, Stephen S. Whitehead, Joseph E. Blaney
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Publication number: 20200036538Abstract: Disclosed are physical unclonable functions (“PUFs”) that provide both a hardware timestamp and an encryption key. The timestamp is more accurate than traditional timestamps generated by software calls to the computing device's operating system, while the encryption key can be used for, among other things, securing time-synchronization packets sent across a network. By combining timestamp generation with encryption key generation, the PUFs provide enhanced security while being cheaper to build and to operate than the specialized cryptographic hardware that they replace.Type: ApplicationFiled: July 30, 2018Publication date: January 30, 2020Applicant: The United States of America as represented by the Secretary of the NavyInventor: Rohan Y. Ramlall
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Publication number: 20200033441Abstract: A radar pulse generator includes a multiplexer, a polyphase synthesizer, a first signal channel and a second signal channel. The multiplexer has a baseband radar pulse input, a multiplexer control input, a first channel output and a second channel output. The baseband radar pulse input signal is a single channel baseband radar pulse signal. The multiplexer control input signal selects one of the group consisting of the first channel output and the second channel output. The polyphase synthesizer synthesizes the first channel output signal, synthesizes the second channel output signal and outputs a desired radar pulse signal based on the synthesized first channel output signal and the synthesized second channel output signal. The first signal channel provides the first channel output signal from the first channel output to the polyphase synthesizer. The second signal channel provides the second channel output signal from the second channel output to the polyphase synthesizer.Type: ApplicationFiled: July 25, 2018Publication date: January 30, 2020Applicant: United States of America as represented by Secretary of the NavyInventors: Michael P. Civerolo, Nicholas T. Johnson, Nicholas A. Lumsden, Colin J. O'Brien
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Publication number: 20200036399Abstract: Disclosed is a transceiver that includes a three-dimensional array of Josephson junctions. When transmitting, the junctions drive an array of micro-antennas. When receiving, the micro-antennas drive the array of Josephson junctions. By extending the junction array into the third dimension, this transceiver packages a large number of Josephson junctions into a small volume, thus increasing the power of a transmitted beam. Multiple different micro-antenna arrays can be included, thus allowing the transceiver to work efficiently at multiple frequency ranges.Type: ApplicationFiled: July 30, 2018Publication date: January 30, 2020Applicant: The United States of America as represented by the Secretary of the NavyInventors: Lee Lemay, Marcio Calixto de Andrade
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Patent number: 10544392Abstract: Disclosed are methods of isolating T cells and TCRs having antigenic specificity for a mutated amino acid sequence encoded by a cancer-specific mutation. Also disclosed are related methods of preparing a population of cells, populations of cells, TCRs, pharmaceutical compositions, and methods of treating or preventing cancer.Type: GrantFiled: April 29, 2016Date of Patent: January 28, 2020Assignee: The United States of America, as represented by the Secretary, Department of Health and Human ServicesInventors: Alena Gros, Steven A. Rosenberg
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Patent number: 10546703Abstract: A switch mechanism has a compliant buckling bar that includes a single fixed end mounted to a mounting surface and a free end that is displaced with respect to the fixed end. The mounting of the fixed end to the mounting surface may constitute the only fixed connection between the bar and the mounting surface. The bar moves between two stable positions in response to a transition force applied transversely to the free end. Residual stress in the bar may be higher when the free end is at each of the stable positions than when the free end is at a neutral position located between the stable positions.Type: GrantFiled: February 20, 2018Date of Patent: January 28, 2020Assignee: United States of America as represented by the Secretary of the Air ForceInventor: James J. Joo
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Patent number: 10546130Abstract: A Timed Attestation Process (TAP) utilizes a CPU bus cycle counter/timer to accurately measure the time needed to calculate a specific function value for an attestation query in an embedded system. The attestation query takes into account embedded software and the hardware data path. An attestation value database stores the unique timing and function data associated with each hardware design element in the embedded device, which each have unique timing characteristics. By utilizing the CPU bus cycle counter/timer of the client device, the TAP increases the time accuracy to the smallest tolerance possible relative to a particular CPU (typically +/?one instruction cycle). The integrity of the embedded software contained in the permanent storage elements and the hardware timing to access each component is verifiable against the unique timing characteristics stored in the database. With this timing characteristic, each hardware element is linked to a specific software configuration.Type: GrantFiled: February 24, 2017Date of Patent: January 28, 2020Assignee: United States of America as represented by the Secretary of the Air ForceInventor: Richard R Chaney