Abstract: Clostridium perfringens can cause food poisoning and is a major agent in necrotic enteritis. As laws banning the use of antibiotics in animal feed become more common, the need for alternatives to antibiotics becomes greater. Peptidoglycan hydrolases that target the cell wall of specific bacteria are one such alternative. Genes for four endolysins, PlyCP10, PlyCP18, PlyCP33, and PlyCP41, were found within clusters of phage associated genes, likely prophages from strains Cp10, Cp18, Cp33, and Cp41. PlyCP18 and PlyCP33 harbor L-alanine amidase catalytic domains, and PlyCP10 and PlyCP41 have glycosyl hydrolase catalytic domains as predicted by BlastP and PFAM searches. All four genes were synthesized with E. coli codon optimization, expressed in E. coli expression vectors with a 6×His tag for nickel column purification, and the recombinant proteins purified. The four endolysins were capable of lysing the 66 C. perfringens strains tested but not the other bacteria tested.

Abstract: Compounds, called liamocins from Aureobasidium pullulans, having the general structure in Formula 1 are disclosed. where R1 is either COCH3 or H; and R2 is between two to ten O-linked 3,5-dihydroxydecanoate; and R3 can be a polyol (e.g., L- or D-glycerol, L- or D-threitol, L- or D-erythritol, L- or D-arabitol, L- or D-xylitol, L- or D-lyxitol, L- or D-ribitol, L- or D-allitol, L- or D-altritol, L- or D-mannitol, L- or D-iditol, L- or D-gulitol, L- or D-glucitol (also called sorbitol), L- or D-galactitol (also called dulcitol), and L- or D-talitol), 2-amino-D-mannitol, 2N-acetylamino-D-mannitol, L-rhamnitol, or D-fucitol; except when R3 is D-mannitol, R2 is not 2 nor 3 O-linked 3,5-dihydroxydecanoate chains. These liamocins described above in addition to D-mannitol liamocin A1, D-mannitol liamocin A2, D-mannitol liamocin B1, and D-mannitol liamocin B2, alone or in combination with each other, can be used to kill certain bacteria and to treat certain bacterial infections.

Abstract: A cascade wind tunnel T-bar turbulence generating grid for creating a turbulence intensity in an air flow having an air flow volume for testing at least two turbine blades having a turbine blade dimension and a pitchwise location, the turbulence generating grid comprising a plurality of cross bars having a front surface and a cross bar gap, a plurality of vertical bars having a vertical bar front surface and a cross bar gap and at least two support bars assembled to form a plurality of air flow. The support bar at an angle ? to the air flow and about parallel to the turbine blades. The cross bars mounted to the support bar such that the cross bar front surface is perpendicular to the air flow. The vertical bars are mounted to the support bar such that the vertical bar front surface is perpendicular to the air flow and wherein the vertical bar gap and a horizontal gap provide the turbulence intensity about constant across the pitchwise location.

Abstract: The invention is directed to a more efficient lentiviral vector comprising a nucleic acid sequence encoding a human ?-globin protein or a human ?-globin protein, which is oriented from 5? to 3? relative to the lentiviral genome. The invention also provides a composition and method utilizing the lentiviral vector.

Abstract: Systems and methods are provided for enhancing the electrical performance of ultra-wideband (UWB) electronically scanned arrays (ESA) for use in multifunctional, electronic warfare, communications, radar, and sensing systems. Embodiments of the present disclosure provide designed metal and dielectric elements placed above the arbitrary radiator (i.e., in the superstrate region) to simultaneously aid impedance and polarization challenges. These elements can be compatible with arbitrary antenna element types.

Abstract: Mobile collection and vetting of user supplied information is described. The systems, techniques, devices, methods, and approaches described herein can be used to obtain, validate, and vet information, such as customs information, in a mobile environment. In embodiments, methods comprise receiving information input via a mobile device. The information is encapsulated by an intermediate to escort the information through a firewall to the database. In response to vetting the information to determine if it meets one or more criteria, the method involves creating a record associated with a unique identifier, information that bio-identifies a user, or an indication of a determination that results from the vetting. In this embodiment, the method includes generating an electronic receipt for communication to the mobile device, the electronic receipt including the unique identifier.

Abstract: An optomechanical gravimeter includes: a first and second accelerometer; and a spacer member interposed between the first accelerometer and the second accelerometer such that the first accelerometer and the second accelerometer independently include: a basal member; a test mass disposed on the basal member; a flexural member interposed between the basal member and the test mass such that the test mass is moveably disposed on the basal member via flexing of the flexural member; an armature disposed on the basal member and opposing the test mass and the flexural member such that: the armature is spaced apart from the test mass; a cavity including: a first mirror disposed on the test mass; a second mirror disposed on the armature, the spacer member providing a substantially constant distance of separation between a first measurement point of the first accelerometer and a second measurement point of the second accelerometer.

Abstract: Embodiments relate to visualization of positional geospatial uncertainty. Initially, a map image request for geographic features is received from a client computing device, where the map image request includes an uncertainty type, a distribution shape, and a selected visualization technique. An uncertainty buffer pixel size is determined based on a geographic distance covered by the distribution shape.

Abstract: The present invention relates, in general, to attenuated swine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated swine influenza viruses having modifications to a swine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations.

Abstract: A process for producing a metal foam. The process includes mechanically working a metallic powder such that oxide particles and/or dissolved oxygen are finely dispersed within a metallic matrix of the metallic particles that make up the metallic powder. The mechanically worked metallic powder is then annealed in a reducing atmosphere, where the reducing atmosphere is an atmosphere that results in the reduction of oxide and/or dissolved oxygen into vapor or gas molecules such that intraparticle porosity is formed within the metallic matrix by conversion of the oxide particles and/or dissolved oxygen to create vapor or gas molecules.

Abstract: A system is provided for use with an optical input signal for detecting a phase difference between a first RF signal having a first phase and a second RF signal having a second phase. The system includes and optical waveguide, a first optical resonant cavity, a first RF receiver, a second optical resonant cavity and a second RF receiver. The optical resonant cavities include a non-linear electro-optical material. The first RF receiver affects the first non-linear electro-optical material of the first optical resonant cavity. The second RF receiver affects the second non-linear electro-optical material of first optical resonant cavity. The optical waveguide outputs an optical output signal based on the optical input signal as modified by the first optical resonant cavity as affected by the first RF receiver receiving the first RF signal and as modified by the second optical resonant cavity as affected by the second RF receiver.

Abstract: A radiofrequency (RF) localization system can include an RF sensing component, a signal-processing module and a visualization element. A plurality of antennas mounted on a belt, or on a helmet, or at least one extendable antenna attached within a backpack could be used for the RF sensing component. The signal-processing module can receive an RF Signal-of-Interest (SOI), and can further compute localization information for the RF SOI such as line of bearing, signal-to-noise ratio (SNR), and SSID information. The visualization element can be an augmented reality (AR) visor mounted on the helmet, or AR glasses. The signal-processing module can be mounted to the helmet, visor, or glasses, as applicable. The RF sensing component, signal module and said visualization element can be worn by the user, and can cooperate to provide hands free RF localization information in an AR format to an end user.

Abstract: A bioreactor and methods for use can include a microfibrous scaffold, that can be made of a composite bioink, and that can have endothelial cells directly embedded within the scaffold using an additive manufacturing process. The scaffold can further be seeded with cardiomyocytes. The hydrogel scaffold can be composed of a plurality of serpentine layers, with each serpentine layers, which can be placed on each other in a cross-hatch configuration, so that the primary axes of successive layers are perpendicular. This configuration can establish an aspect ratio for the scaffold, which can be selectively varied. For greater strength, the successive layers that have a primary axis in the same direction can be placed in the scaffold so that they are slight offset from each other. The scaffold can be placed in the bioreactor with perfusion, for use in cardiovascular drug screening and other nanomedicine endeavors.

Abstract: An augmentation amplifier is provided for aspirating gas flow from a surrounding medium. The amplifier connects at an inlet to a pressurized gas source and at an outlet to a gas receiver. Ambient gas from the medium supplements source provided compressed gas. The amplifier includes a Venturi conduit including a throat, an external cavity and a diffusion chamber. The conduit receives and flows pressurized gas from the inlet to the throat. The cavity receives ambient gas from the medium. The chamber expands and accelerates the pressurized gas from the throat to entrain the ambient gas via aspiration. The accelerated and ambient gases combine into an exhaust gas to the outlet.

Abstract: A method to calculate position comprising the steps of creating a positioning system, wherein the positioning system comprises at least one satellite, at least one user, and at least one fixed ground site, and wherein the at least one satellite is coupled to a modulating retroreflector and a laser communications receiver, and wherein the at least one user comprises a space object tracking lidar system and a laser communications receiver, and wherein the at least one fixed ground site comprises a space object tracking lidar system and a laser communications transmitter and is configured to determine range and range rate to the modulating retroreflector; using the range and range rate to update the fixed ground site's estimate of a satellite ephemeris; configuring the at least one fixed ground site to use the laser communications transmitter to uplink the ephemeris to the at least one satellite's laser communications receiver; recording the ephemeris into the at least one satellite and replace ephemeris previou

Abstract: Compositions including a fatty acid, such as an odd chain fatty acid or a very long even chain fatty acid, and salts and derivatives thereof, and methods of use in support of planned supplement and food ingredient products for diagnosis and treatment of anemia.

Abstract: The present invention is directed to aqueous solid polymer electrolytes that comprise a lithium salt and battery cells comprising the same. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies.

Abstract: A reconfigurable metamaterial apparatus, having a metamaterial structure capable of focusing incoming radiation, the incoming radiation having at least one of a normal incoming radiation and an off-axis incoming radiation. The metamaterial structure has a matrix frame structure and an array of elements disposed in relation to the matrix frame structure. The array has a refractive index gradient profile. Each element has a material with a specific refractive index corresponding to its location in the array; and each element has an alterability feature for facilitating selectively altering its refractive index. The alterability feature has at least one of an interchangeability feature and a tunability feature. The refractive index gradient profile is at least one of tunable and optimizable for at least one parameter of focal stength and frequency, whereby undesirable signals from the incoming radiation are wave-guidable for areal dissipation, and whereby delicate equipment is protectable.

Abstract: Apparatus and methods for forming and printing hollow bodies from amorphous materials to form three-dimensional objects are provided. Apparatus provide a hollow body forming and printing machine, and methods for determining a desired amount of impact deformation for the hollow spheres, including calculating specific characteristics of the hollow spheres and the amorphous material, deriving a target viscosity range, adjusting the apparatus to satisfy the target viscosity range, and using the apparatus to form a plurality of hollow spheres with controlled deformation.

Abstract: A computer-implemented method is provided for maximizing surveillance volume in a radar system. This includes determining saturation range probability fsat; determining sensitivity probability fsens; calculating surveillance volume from multiplying the saturation range probability by the sensitivity probability as Vs=fsatfsens; and adjusting the radar system to maximize the surveillance volume.