Abstract: The invention provides orvinol and thevinol compounds useful for the treatment of drug and alcohol abuse, the compounds being particularly useful for the prevention of relapse in recovering addicts.

Abstract: The invention provides vesicles that may be used in diagnosing infection, especially with infection by bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. The vesicles can be used in wound dressings.

Abstract: The invention relates to compositions having RGS (regulator of G-protein Signaling) inhibiting activity, and methods of use thereof. In some embodiments, RGS-inhibiting compositions find use in research on or treatment of disease states (e.g., diabetes, epilepsy, neuropathic pain, depression and other diseases).

Abstract: A hollow fibre containing one or more layers having a mean pore size in one or more of said layers of less than 100?m. The invention also extends to a method for preparing porous hollow fibres and to the apparatus for preparing said fibres.

Abstract: This invention relates to a method for modifying cell proliferation in a plant which comprises the step of transforming a plant, or plant propagating material, with a nucleic acid molecule comprising at least one regulatory sequence capable of directing expression within the integuments and/or seed coat and at least one nucleic acid sequence whose expression or transcription product is capable of directly or indirectly modulating cell proliferation, whereby on expression of that nucleic acid sequence cell proliferation is modified. The invention also relates to a plant which includes a nucleic acid molecule comprising at least one regulatory sequence capable of directing expression within integuments and/or seed coat an at least one nucleic acid sequence whose expression or transcription product is capable of directly or indirectly modulated cell proliferation, whereby on expression of that nucleic acid sequence cell proliferation is modified.

Abstract: A reactor for carrying out a heterogeneously catalyzed reaction includes at least first and second reaction zones that are arranged in series and that each include catalytic material, heat transfer zones that are located between said serially arranged reaction zones, and a pulse-generating device, which is arranged to deliver pulses to liquid in the reactor. The reactor allows three-phase reactions to be carried out efficiently and can reduce the impact of deposited reaction by-products on reaction efficiency.

Abstract: A formulation for use as a bactericidal agent in the human or animal digestive system includes xanthine oxidoreductase. The formulation may especially be in the form of a formula feed formulation or enteral feed formulation for administration to a human or animal. The formulation is capable of functioning as a “natural antibiotic” to prevent or reduce bacterial infection within the gut, especially the neonatal gut.

Abstract: A composition for use in the treatment of lesions of the human or animal body comprises xanthine oxidoreductase and a pharmaceutically acceptable electron donor system. The composition can accelerate wound healing, especially in a hypoxic environment.

Abstract: A system for detecting a fault in a power line (1) includes, in the power line (1), a first circuit (4) capable of attenuating signals within a first frequency band, which is centered on a first frequency, substantially more than it attenuates signals outside the first frequency band, and, a second circuit (5) connected to the power line (1) on one side of the first circuit (4), the second circuit (5) being capable of extracting signals within a second frequency band that includes the first frequency. The relative levels of two signals extracted by the second circuit (5), are detected and signalled, the two signals being at respective frequencies which the first circuit is capable of attenuating by different relative amounts.

Abstract: This disclosure relates to vibration damping supports and in particular to a suspension unit for a stretcher.The stretcher support unit comprises a rectangular base frame (10) on which is supported, by means of a resilient support mechanism, a stretcher frame or carrier (11). The support mechanism comprises a pair of cantilever arms (20) inclined upwards in opposite directions and each pivotally mounted at its lower end on the base frame (10). The movements of the cantilever arms (20) are controlled by respective gas-liquid suspension units (30), which are mounted between the base frame (10) and an extension arm (28) of each cantilever arm (20). The suspension units comprise, in one embodiment, a gas reservoir (70), a sealed liquid reservoir (71), a flexible diaphragm (72) forming one end of the liquid reservoir and an actuator piston (73).