Abstract: Tomography apparatus comprises: a plurality of electrodes arranged around a perimeter of a cross section of a sample volume for containing a liquid or mixed-phase sample, each electrode being arranged to be in electrical contact with a sample contained in the sample volume; measurement means adapted to perform a set of measurements, each measurement comprising driving a current between a first respective adjacent pair of said electrodes and measuring a voltage developed across a second respective adjacent pair of said electrodes; and processing means adapted to generate a tomogram indicative of sample conductivity over said cross section from said set of measurements. The processing means is arranged to calculate sample conductivity values of a portion of said cross section from said set of measurements and generate said tomogram from said calculated sample conductivity values of said portion using an assumption of symmetry.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.

Abstract: A method of forming an implantable tissue engineered construct, a bioreactor for forming a tissue engineered construct, and a tissue engineered construct itself are disclosed The method includes seeding a scaffold with cells to form a tissue construct; locating the tissue construct in a space defined by a tissue construct support element; locating the tissue construct support element within a bioreactor; and operating a load applicator of the bioreactor to apply a cyclical compressive mechanical load to the tissue construct, to stimulate the deposition of tissue matrix in the tissue construct, in which the tissue construct, the tissue construct support element and the load applicator are arranged so that the load applicator can at least initially contact both the tissue construct and the tissue construct support element, so that at least part of a total load generated by the load applicator is borne by the tissue construct support element.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure.

Abstract: This document provides methods and materials for treating cancer. For example, methods and materials for treating cancer using combinations of antigens are provided. For example, VSV vectors designed to express a GNAQ antigen, a TYRP1 antigen, and an N-RAS antigen can be used to reduce the number of cancer cells (e.g., uveal melanoma cells) within a mammal (e.g., a human). In some cases, VSV vectors designed to express a BRAF antigen, a TOPO-lla antigen, and a YB-I antigen can be used to reduce the number of cancer cells (e.g., skin melanoma cells) within a mammal (e.g., a human). The composition can comprise less than 50 separate nucleic acid molecules.

Abstract: This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.

Abstract: The present invention provides an electrolyte component containing one or more salts including lithium bis(oxalate)borate (LiBOB), a solvent, propylene carbonate (PC) and a crystallizable polymer wherein said LiBOB is present as a weight percentage of 0.5% or more, said propylene carbonate is present as a weight percentage of between 5% and 90% and the crystallizable polymer is present at a weight percentage of greater than 1%. It also provides a galvanic cell formed from the above and a process for forming same.

Abstract: There is described variegin for use as a medicament in the treatment of disease or condition characterised in that the variegin is administered in an amount of at least about 0.1 mg/kg (mass of drug compared to mass of patient).

Abstract: A medical magnetometer 10 comprising one or more induction coils 2 for detecting a time varying magnetic field of a region of a subject's body, such as the heart. Each coil has a maximum outer diameter of 4 to 7 cm, and a configuration such that the ratio of the coil's length to its outer diameter is at least 0.5, and the ratio of the coil's inner diameter to its outer diameter is 0.5 or less. Each induction coil 2 is coupled to a respective detection circuit comprising a low impedance pre-amplifier 3, a low pass filter 5, a notch filter 6 to remove line noise, and an averaging element 7. Each detection circuit produces an output signal 9 for use to analyze the time varying magnetic field of the region of the subject's body.

Abstract: This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors within a mammal (e.g., a human) are provided.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.

Abstract: The disclosure relates to a method of detecting a structural change in a molecule that is attached to a surface that is electrically conductive, wherein the method includes monitoring the phase of the electrochemical impedance at the surface, and wherein a change in the phase indicates a change in the structure of the molecule. The disclosure also relates to arrays and methods for making arrays having molecules, such as polypeptides, attached to electrically conductive surfaces, such as electrodes.

Abstract: The disclosure relates to anti-viral agents that mimic or inhibit packaging singles of RNA viruses that function in viral capsid formation and their use in the control of viral infection.

Abstract: The present invention relates to a dysprosium-doped tellurite or germanate glass characterised by a fluorescence peak in the mid-IR spectrum.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibers characterized in that each of the ribbons, fibrils or fibers have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.

Abstract: The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.

Abstract: The invention provides a spun yarn comprising recycled carbon fiber, and a method for the production thereof. The recycled carbon fiber comprises discontinuous carbon fiber and, optionally, continuous carbon fiber, and may be recycled from various sources, such as end-of-life waste and manufacturing waste. The yarn which is produced shows the required degree of strength and durability, and can be used in all conventional composite manufacturing operations where virgin yarn is currently employed, such as woven fabric manufacture, unidirectional fabric manufacture, filament winding, pultrusion and the like.

Abstract: A THz quantum cascade laser is used to investigate a target by directing a first beam of laser radiation from the laser at the target to thereby produce a second beam of laser radiation by interaction of the first beam with the target. Self-mixing of the first and second beams occurs within the laser and causes variations in a signal such as the operating voltage of the laser. An operating parameter of the laser that affects the interaction of the first beam with, the target is varied. The operating voltage is monitored and processed to determine phase and amplitude changes associated with material properties of the target. Consequently in one embodiment the invention provides for processing the variations in the signal to produce various images of the target.

Abstract: There is described a material comprising tapes, ribbons, fibrils or fibres characterized in that each of the ribbons, fibrils or fibres have an antiparallel arrangement of peptides in a ?-sheet tape-like substructure wherein the material comprises a pair of self assembling complementary polypeptides.