Abstract: Methods of obtaining renewable sources of taxanes including taxol are provided. Compositions comprising taxanes which are useful as source materials for the further purification of taxanes are also disclosed. Specifically, a method of drying plant matter to preserve their taxane content and facilitate their extraction is disclosed. In addition, methods of extracting and purifying taxol and other taxanes from ornamental cultivars using a series of organic and aqueous solvents and normal phase chromatography columns are also disclosed.

Abstract: Method of promoting healing of a wound by administering turmeric to a patient afflicted with the wound.

Abstract: The present invention is directed to compounds which suppress immune responses and/or selectively inhibit complement. These compounds contain an aromatic ring and are substituted dihydrobenzofurans, spirobenzofuran-2(3H)-cycloalkanes, and their open chain intermediates. The compounds of the present invention, and the pharmaceutically acceptable salts thereof, interrupt the proteolytic processing of C5 to bioactive components, exhibit immunosuppressive activities, and have therapeutic utility in the amelioration of disease and disorders mediated by complement and/or immune activity.

Abstract: Suppository formulations having long-term stability and containing readily bioavailable .DELTA..sup.9 -THC derivatives.

Abstract: The present invention is directed to compounds which suppress immune responses and/or selectively inhibit complement. These compounds contain an aromatic ring and are substituted dihydrobenzofurans, spirobenzofuran-2(3H)-cycloalkanes, and their open chain intermediates. The compounds of the present invention, and the phamaceutically acceptable salts thereof, interrupt the proteolytic processing of C5 to bioactive components, exhibit immunosuppressive activites, and have therapeutic utility in the amelioration of disease and disorders mediated by complement and/or immune activity.

Abstract: The method of identification of the country of origin of CANNABIS (Marijuana). The method comprises gas chromatographic/mass spectrometric analysis of extracts of multiple samples of marijuana plant material from a country or geographical location, preparing a location profile from the chemical profiles made from analysis of the multiple samples from a specific country or location. The analyzed profile of a sample of unknown origin is compared with the location profiles of the various countries growing marijuana.

Abstract: New analogs of sampangine and cleistopholine, compositions and methods of preparation thereof, method of treating fungal and mycobacterial infections. The compounds have the general formula: ##STR1## where the R.sub.1, R.sub.2, and R.sub.5 groups are defined herein.

Abstract: The present invention is directed to compounds which suppress immune responses and/or selectively inhibit complement. These compounds contain an aromatic ring and are substituted dihydrobenzofurans, spirobenzofuran-2(3H)-cycloalkanes, and their open chain intermediates. The compounds of the present invention, and the pharmaceutically acceptable salts thereof, interrupt the proteolytic processing of C5 to bioactive components, exhibit immunosuppressive activities, and have therapeutic utility in the amelioration of disease and disorders mediated by complement and/or immune activity.

Abstract: A unidirectional flow heart valve includes a passageway having an inlet side and an outlet side. A disk occluder is disposed within the passageway. The disk occluder has a closed position wherein the disk occluder occludes fluid flow through the passageway and an open position wherein the disk occluder permits fluid flow through the passageway. A fulcrum causes the disk occluder to pivot off center between the open and closed positions. An electromagnetic control mechanism forces the disk occluder to remain closed when energized until a predetermined net pressure is reached against the disk occluder. When the electromagnetic control mechanism is either selectively deenergized or the force on the occluder disk is greater than the holding force of the electromagnetic control mechanism, the disk occluder is released from the closed position to pivot on the fulcrum in response to fluid pressure.

Abstract: A new compound 3-Methoxysampangine and its analogs, compositions thereof, and method of using as an antifungal agent particularly effective against Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus.

Abstract: The use of the naturally occurring and readily synthesized alkaloid compound onychine as an antimicrobial agent and particularly against Candida albicans organism.

Abstract: The use of cannabichromene (CBC) and its homologues and isomers to induce hypothermia, reduce inflammation in mammals, and as antimicrobial agents is disclosed. Preferably, a compound selected from cannabichromene, its homologues and isomers, is administered as a novel composition, in combination with a pharmaceutically acceptable diluent carrier.

Abstract: A naturally occurring anorexic composition of matter that does not alter locomotor function comprising the water soluble constituents of the coca leaf (Erythroxylon coca). Anorexic compositions consisting of the foregoing described product prepared from coca leaves in admixture with a non-toxic, pharmaceutically acceptable carrier. A method of suppressing appetite levels in animals comprising administering a therapeutically effective concentration of the inventive product in a pharmaceutically suitable carrier intravenously, orally, intraperitioneally and intramuscularly. The method of preparing an anorexically active product from coca leaves.

Abstract: Compounds, compositions and a method of treatment to tolerize and desensitize mammals sensitive to the allergenic moities found in plants of the Anacardiaceae and Ginkgoaceae families comprising the reaction product of poison ivy urushiol, poison oak urushiol, poison sumac urushiol & mixtures thereof, 3-n-alkane substituted catechol derivatives having 11 to 19 carbon atoms and the unsaturated olefinic congeners thereof with an acyl ester functioning group esterifying the catecholic hydroxy constituents of the aforementioned compounds or cell membrane residues.

Abstract: The preparation of cannabichromene (CBC) and homologues thereof by condensation of citral with a substituted resorcinol in the presence of a primary amine, and the use of these compounds to induce hypothermia and reduce inflammation in mammals, is disclosed. Preferably, the cannabichromene is administered as a novel composition, in combination with a pharmaceutically acceptable diluent carrier. A new compound 2-methyl-2(4-methyl-pent-3-enyl)-5-hydroxy-7-methylchromene (CBC-C.sub.1).

Abstract: Antimicrobial compositions useful in mammal and plants comprising liriodenine, dehydroglaucine, liriodenine methiodide and oxoglaucine methiodide compounds and mixtures thereof. The antimicrobial compositions are particularly useful against Gram positive bacteria, acid fast bacteria and fungi and yeast.

Abstract: A method of detecting the presence of paraquat in biological tissues and fluid and soil and plant tissues, particularly marihuana, involving the conversion of any paraquat present in the tissue to 4,4'-bipyridine and analyzing the sample for that compound, the presence of which would indicate the presence of paraquat in the tissue.

Abstract: Antimicrobial compositions useful in mammal. An extract of the heartwood of Liriodendron tulipifera L., provides components and derivatives thereof useful as antimicrobial agents; antimicrobial compositions comprising liriodenine, dehydroglaucine liriodenine methiodide and oxoglaucine methiodide compounds of and derivatives and mixtures thereof of alkaloids isolated from the extract of the heartwood of Liriodendron tulipifera L. The antimicrobial compositions being particularly useful against Gram positive bacteria, acid fast bacteria and fungi and yeast.

Abstract: A process for N-trifluoroacetylating an amino compound, such as an amino acid or a peptide, comprising reacting the amino compound with sym-trichlorotrifluoroacetone in a dimethyl sulfoxide solvent under substantially neutral conditions.