Patents Assigned to The University of Newcastle
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Patent number: 12251411Abstract: A method for treating endometrial cancer comprising: administering to a patient a cannabis extract (CE) wherein the cannabis extract comprises cannabidiol (CBD) at between 50% and 99% by weight of the CE.Type: GrantFiled: September 15, 2023Date of Patent: March 18, 2025Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Patent number: 12215374Abstract: The present invention relates to organic thin film sensors and the preparation and use thereof in sensing applications, and in particular in glucose sensing. The sensor is characterised by a layered structure comprising a porous wicking layer whose surface is configured to receive a liquid sample. An enzyme is disposed on or within the porous layer for facilitating the generation of a charge carrier from an analyte. A polymer layer in contact with the porous layer is connected to an ohmic conductor for applying a gate voltage to the polymer layer, the polymer layer being conductive to the charge carrier; and an organic semiconducting layer is connected to a source electrode and a drain electrode.Type: GrantFiled: May 15, 2019Date of Patent: February 4, 2025Assignee: The University of NewcastleInventor: Paul Dastoor
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Patent number: 12097211Abstract: Disclosed herein are methods for treating estrogen sensitive disease, specifically toward endometrial cancers, and compositions used to treat the estrogen sensitive disease. Methods for treating estrogen sensitive diseases comprise administering to a patient an effective amount of a cannabis extract in the presence of an elevated level of estrogen wherein the estrogen is endogenous estrogen or further comprises exogenous estrogen and wherein the methods may further comprise the addition of a chemotherapeutic agent.Type: GrantFiled: October 25, 2023Date of Patent: September 24, 2024Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar
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Publication number: 20240272175Abstract: Provided herein are methods for diagnosing functional gastrointestinal disorders such as functional dyspepsia and irritable bowel syndrome, comprising detecting IgG antibodies in a sample obtained from a subject, wherein the IgG antibodies recognise one or more antigens from Streptococcus salivarius. Also provided are kits for detecting IgG antibodies for use in the diagnosis of functional gastrointestinal disorders, and methods for selecting subjects for treatment for functional gastrointestinal disorders.Type: ApplicationFiled: June 7, 2022Publication date: August 15, 2024Applicants: The University of Newcastle, The University of QueenslandInventors: Simon KEELY, Nick TALLEY, Grace BURNS, Mark MORRISON
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Patent number: 12011451Abstract: Compositions and methods of use of treatment of one or more of ovarian cancer, endometrial cancer, head and neck cancer, noncancerous gynecological disorders, and estrogen sensitive cancers, the composition comprising an effective amount of a cannabinoid and a flavonoid wherein the method comprises administering to a patient in need thereof an effective amount of the composition and optionally administering the composition concomitantly with a chemotherapeutic agent.Type: GrantFiled: October 25, 2023Date of Patent: June 18, 2024Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar
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Patent number: 11994513Abstract: Provided herein are methods for detecting an estrogen-induced cancer in a subject, for identifying a subject at risk of developing an estrogen-induced cancer and for determining or predicting prognosis for a subject with an estrogen-induced cancer. The methods of the disclosure comprise determining the level of expression of ALPPL2 in a biological sample, typically a blood sample, obtained from a subject.Type: GrantFiled: March 29, 2019Date of Patent: May 28, 2024Assignee: The University of NewcastleInventor: Pradeep S. Tanwar
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Patent number: 11986505Abstract: A method for treating a noncancerous gynecological disorder comprising: administering to a patient and effective amount of composition comprising a cannabis extract comprising cannabidiol (CBD) wherein the composition is preferably administered in a mucosal form, such as intravaginally.Type: GrantFiled: April 13, 2023Date of Patent: May 21, 2024Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Patent number: 11975036Abstract: Methods for treating ovarian cancer comprising: administering to a patient and effective amount of a cannabis extract comprising CBD wherein preferably the cannabis extract is administered via a mucosal formulation.Type: GrantFiled: April 13, 2023Date of Patent: May 7, 2024Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Publication number: 20240068811Abstract: Example implementations relate to gyroscopes comprising: a cyclic symmetric proof mass for bearing on a first surface degenerate, spatially orthogonal primary and secondary modes of vibration which become coupled in response to rotation about an axis of the proof mass; at least one actuator for inducing a primary surface acoustic wave of circumferential order n associated with the primary mode; and at least one sensor for sensing a secondary surface acoustic wave of circumferential order n associated with the secondary mode.Type: ApplicationFiled: December 21, 2021Publication date: February 29, 2024Applicant: The University of Newcastle Upon TyneInventors: James Burdess, Barry Gallacher
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Patent number: 11793847Abstract: A method for treating endometrial cancer comprising: administering to a patient a cannabis extract (CE) wherein the cannabis extract comprises cannabidiol (CBD) at between 50% and 99% by weight of the CE.Type: GrantFiled: October 26, 2022Date of Patent: October 24, 2023Assignees: Ecofibre USA Inc., The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Patent number: 11654171Abstract: Methods for treating ovarian cancer comprising: administering to a patient and effective amount of a cannabis extract comprising CBD, wherein preferably, the cannabis extract is administered via a mucosal formulation.Type: GrantFiled: October 26, 2022Date of Patent: May 23, 2023Assignees: Ecofibre Limited, The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Patent number: 11654172Abstract: A method for treating a noncancerous gynecological disorder comprising: administering to a patient and effective amount of composition comprising a cannabis extract comprising cannabidiol (CBD), wherein the composition is preferably administered in a mucosal form, such as intravaginally.Type: GrantFiled: October 26, 2022Date of Patent: May 23, 2023Assignees: Ecofibre Limited, The University of NewcastleInventors: Alexandra M. Capano, Pradeep Singh Tanwar, Alex Nance
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Patent number: 11471895Abstract: A method of preparing a water in oil emulsion comprises forming a mixture of oil and emulsifying agent, progressively adding an aqueous salt solution to the mixture and dispersing the aqueous salt solution into the mixture. A concentrated water in oil emulsion is formed with drops of the aqueous salt solution (1) packed inside the oil solution phase (2). The emulsion is added to water and then mixed so that the emulsion absorbs the water. The salt concentration of the emulsion relative to the salt concentration of the water is controlled. Methods of agglomerating fine hydrophobic particles in a slurry using the water in oil emulsion are provided, where the emulsion is added to the slurry and then mixed so that the emulsion absorbs the water in the slurry. The salt concentration of the emulsion relative to the salt concentration of the slurry is controlled.Type: GrantFiled: August 4, 2017Date of Patent: October 18, 2022Assignee: The University of NewcastleInventors: Kevin Patrick Galvin, Kim van Netten
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Patent number: 11419864Abstract: Provided herein are methods of detecting or determining aging and/or oxidative damage in tissue, including placental tissue, skin, kidney and brain tissue. One embodiment provides a method for detecting or determining aging in body tissue, comprising measuring one or more markers of aldehyde oxidase 1 (AOX1) expression or activity in a biological sample, wherein the level of AOX1 expression or activity, or of the one or more markers, is indicative of aging in the tissue. Also provided herein are methods of treating a disease or condition associated with ageing or oxidative damage in one or more cells or tissues, comprising administering to a subject in need thereof an inhibitor of AOX1.Type: GrantFiled: March 2, 2018Date of Patent: August 23, 2022Assignee: The University of NewcastleInventors: Roger Smith, Kaushik Maiti
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Patent number: 11407955Abstract: A method of agglomerating fine particles such as ultrafine coal in a beneficiation process, uses a water in oil emulsion to significantly reduce the amount of oil needed compared with known oil in water emulsions. A solution of oil and emulsifying agent is provided to which water is progressively added forming a concentrated water in oil emulsion with stabilized water drops (1) packed inside the oil solution phase (2). Fine particles in a slurry are then added, causing the fine particles to collide and stick to the emulsion particles. An optional form of the invention coats tiny portions of the emulsion in a thin film of low viscosity oil (5) to achieve a higher level of selectivity.Type: GrantFiled: January 25, 2013Date of Patent: August 9, 2022Assignee: The University of NewcastleInventor: Kevin Patrick Galvin
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Patent number: 11215397Abstract: A vibration unit assembly for a belt conveyor has a vibration element, and vibration generator and a connection assembly. The vibration generator is operatively connected to the vibration element for inducing vibrations in the vibration element. The connection assembly connects the vibration element to the belt conveyor so that the vibration element may move relative to the belt conveyor. A contact surface of the vibration element engages a material to vibrate and compress the material as it is transported on the belt conveyor. The vibration element may include a plate or a roller. A method for treating a material involves applying a vibration force and applying a compressive force to compact the material. A method for drying a material involves applying a vibration force to the material to release fluid and applying a compressive force to compact the material.Type: GrantFiled: July 17, 2018Date of Patent: January 4, 2022Assignee: The University of NewcastleInventors: Craig Anthony Wheeler, Jens Plinke, Kenneth Charles Williams, Peter William Alexander Robinson, Kevin James Barber, Oliver James Whatnall, John James Warner
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Patent number: 11148171Abstract: An apparatus and method for the dry separation of bulk particulate material, especially coarse particles, is provided. The apparatus comprises a chamber, a screen adjacent the chamber and a fluidising device fluidly connected to the chamber. The screen has a screen surface, a plurality of apertures and an opening larger in size than the aperture. A mixture of the coarse particles and a fine particulate medium is fed into the chamber. The fluidising device directs a fluidising fluid to fluidise a fine particulate medium and create a fluidised bed directed towards the screen. The fine particulate medium and the coarse particles pass from the chamber through the openings. The fine particulate medium passes back through the apertures to the chamber. Relatively high density coarse particles also pass back through the openings to the chamber. Relatively low density coarse particles are retained on the screen surface. Vibrations may also be used.Type: GrantFiled: August 1, 2017Date of Patent: October 19, 2021Assignee: The University of NewcastleInventor: Kevin Patrick Galvin
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Publication number: 20210196687Abstract: There is provided a method for promoting epithelium repair in a subject, the method comprising administering to the subject a therapeutically effective amount of an activator of PI3K/Akt signalling.Type: ApplicationFiled: May 21, 2019Publication date: July 1, 2021Applicants: Telethon Kids Institute, The University of NewcastleInventors: Thomas Iosifidis, Anthony Kicic, Darryl Knight, Stephen Stick
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Patent number: 10952964Abstract: Provided herein are methods and compositions for the targeted delivery to myometrial tissue of one or more agents capable of regulating contractility of myometrial tissue, wherein the one or more agents are contained or encapsulated within a polymeric delivery vehicle conjugated with one or more molecules that recognizes and/or is capable of binding, directly or indirectly, to the oxytocin receptor.Type: GrantFiled: June 7, 2019Date of Patent: March 23, 2021Assignee: The University of NewcastleInventors: Susan Hua, Jonathan Paul, Roger Smith
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Patent number: 10945980Abstract: Provided herein are methods for treating or preventing myopia, or for inhibiting the development of myopia, comprising administering to a subject in need thereof an effective amount of an agent capable of increasing nitric oxide levels in one or more ocular cells or an agent capable of promoting or increasing the expression and/or activity of nNOS in one or more ocular cells. Also provided are methods for inducing or promoting nNOS expression and/or activity in one or more ocular cells, comprising exposing said cells to an effective amount of L-arginine.Type: GrantFiled: June 21, 2017Date of Patent: March 16, 2021Assignee: The University of NewcastleInventor: Sally Anne McFadden