Patents Assigned to The University of North Texas
  • DRUG DELIVERY VEHICLE
    Publication number: 20140045950
    Abstract: The invention provide herein provides for a targeted drug delivery vehicle compositions, methods of manufacture, and methods of treatment for therapeutic applications.
    Type: Application
    Filed: August 7, 2013
    Publication date: February 13, 2014
    Applicants: National Institutes of Health, University of North Texas Health Science Center
    Inventors: Andras G. Lacko, Alan T. Remaley
  • Silver and silver nanoparticle MALDI matrix utilizing online soft landing ion mobility
    Patent number: 8610058
    Abstract: Silver nanoparticles as a sample matrix for Matrix Assisted Laser Desorption Ionization (MALDI) along with a novel method for nanoparticle development is described herein. The silver nanoparticles were generated from silver ions on the surface of a MALDI plate utilizing a Soft Landing Ion Mobility (SLIM) instrument. Upon interaction with the surface the incident silver ions were labile and aggregated into the nanoparticle structures in a time dependent fashion. Post landing analysis were completed by Time of Flight mass spectrometry (TOF), and of particular interest in the spectra were the elimination of low mass interference peaks that generally plague organic based matrices. The approach of the present invention significantly decreases sample preparation time and may lead to a preparation free MALDI source by soft landing a matrix directly on the sample surface.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: December 17, 2013
    Assignee: University of North Texas
    Inventors: Guido Fridolin Verbeck, IV, Stephen Davila
  • Multifunctional micropipette biological sensor
    Patent number: 8602644
    Abstract: The fabrication and use of a multifunctional micropipette biological sensor for in-situ detection of temperature changes, ion conductivity, and light is described herein.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: December 10, 2013
    Assignee: University of North Texas
    Inventor: Tae-Youl Choi
  • Petroleum oil analysis using liquid nitrogen cold stage—laser ablation—ICP mass spectrometry
    Patent number: 8586943
    Abstract: A novel application of a cold-stage coupled to a laser ablation-ICP-MS system is disclosed herein. The novel system of the present invention offers significant advantages over other systems employed for cooling samples prior to LA-ICP-MS analysis. The system discloses herein has multiple applications, including detection of one or more metal contaminants in an oil sample.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: November 19, 2013
    Assignee: University of North Texas
    Inventors: Guido Fridolin Verbeck, IV, William D. Hoffman
  • GRAPHENE (MULTILAYER) BORON NIRIDE HETEROEPTAXY FOR ELECTRONIC DEVICE APPLICATIONS
    Publication number: 20130302562
    Abstract: Disclosed is a substrate-mediated assembly for graphene structures. According to an embodiment, long-range ordered, multilayer BN(111) films can be formed by atomic layer deposition (ALD) onto a substrate. The subject BN(111) films can then be used to order carbon atoms into a graphene sheet during a carbon deposition process.
    Type: Application
    Filed: November 16, 2012
    Publication date: November 14, 2013
    Applicant: UNIVERSITY OF NORTH TEXAS
    Inventor: JEFFRY A. KELBER
  • Organic light-emitting diodes from homoleptic square planar complexes
    Patent number: 8580397
    Abstract: Homoleptic square planar complexes [M(N?N)2], wherein two identical N?N bidentate anionic ligands are coordinated to the M(II) metal center, including bidentate square planar complexes of triazolates, possess optical and electrical properties that make them useful for a wide variety of optical and electrical devices and applications. In particular, the complexes are useful for obtaining white or monochromatic organic light-emitting diodes (“OLEDs”). Improved white organic light emitting diode (“WOLED”) designs have improved efficacy and/or color stability at high brightness in single- or two-emitter white or monochrome OLEDs that utilize homoleptic square planar complexes, including bis[3,5-bis(2-pyridyl)-1,2,4-triazolato]platinum(II) (“Pt(ptp)2”).
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: November 12, 2013
    Assignee: University of North Texas
    Inventor: Mohammad A. Omary
  • Environment-friendly antifoulants for the prevention of biofouling
    Patent number: 8575230
    Abstract: Environmentally-friendly alternatives to organometallic antifoulants that are efficacious at preventing biofouling by organisms such as the zebra mussel. Preferred antifoulant compositions utilize compounds having a Lipophilic-Amide-Spacer-ElectroNegative (“LASEN”) structural motif, such as capsaicin, and compounds having a TetraHydroCannibinoid (“THC”) structural motif. The antifoulant compositions are non-toxic, and effective.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: November 5, 2013
    Assignees: University of North Texas Health Science Center at Fort Worth, The Board of Regents of the University of Texas System
    Inventors: John A. Schetz, Robert F. McMahon
  • SYSTEM AND METHOD FOR MULTI-RESIDUE MULTIVARIATE DATA COMPRESSION
    Publication number: 20130262414
    Abstract: A method for encoding data comprising generating a table having N moduli, where N is a positive integer equal to two or more, where each of a plurality of integers has a unique set of residue values associated with the moduli. Storing or transmitting the first data field value of a sequence of L data fields values, where L is an integer equal to or greater than 2. Storing or transmitting a set of K residue values, where K<N, for each of the successive L?1 data field values of the sequence of M data field values until a set of K residue values for each successive data field value have been stored. Retrieving or receiving the first data field value and the L?1 sets of K residue values. Reconstructing the sequence of L data fields using the multi-residue multivariate encoding table and a table look-up process, using the first value and the L?1 sets of K residue values.
    Type: Application
    Filed: April 1, 2013
    Publication date: October 3, 2013
    Applicant: University of North Texas
    Inventors: Oscar N. Garcia, Shengli Fu
  • Piggy-Back Delivery of Nucleic Acids Into Organisms
    Publication number: 20130230461
    Abstract: The present invention includes nucleic acid hybrid molecules capable of entering cells comprising at least one vivo-morpholino oligonucleotide (vivo-MO) comprising a guanidine-rich head conjugated to the 5? end, and at least one standard oligonucleotide comprising a gene-specific sequence and a standard oligonucleotide pairing sequence, wherein the standard oligonucleotide is bound to the vivo-morpholino oligonucleotide through base pairing to form a hybrid and wherein the vivo-morpholino oligonucleotide pairing sequence is complementary to the standard oligonucleotide pairing sequence.
    Type: Application
    Filed: March 1, 2013
    Publication date: September 5, 2013
    Applicant: UNIVERSITY OF NORTH TEXAS SYSTEM
    Inventor: Pudur Jagadeeswaran
  • Nanomanipulation Coupled Nanospray Mass Spectrometry (NMS)
    Publication number: 20130206976
    Abstract: A coupled nanomanipulation and nanospray mass spectrometry (NMS) system for single cell, single organelle, and ultra-trace molecular analysis is disclosed herein. The system primarily comprises a bio-workstation coupled to a NMS. The bio-workstation primarily comprises of a nanomanipulator stage with a plurality of nano-positioners attached to a cabinet with a piezo voltage source and a pressure injector. The present invention further describes a fingerprint lift method that when coupled with the system disclosed herein can be used for retrieval and analysis of trace amounts of drug and explosive residues. The system described herein has been used in the areas of trace and document analysis within the forensic field, trace fiber analysis, and electrostatic lifts for illicit drugs, as well as document and painting analysis.
    Type: Application
    Filed: March 12, 2013
    Publication date: August 15, 2013
    Applicant: University of North Texas System
    Inventor: University of North Texas System
  • Engineering lipids in vegetative tissues of plants
    Patent number: 8507754
    Abstract: The present invention discloses gene targets and methods for the genetic control of lipid accumulation in vegetative (non-seed) portions of plants. Enhanced lipid, e.g. triacylglycerol (TAG), accumulation in vegetative portions of plants may be obtained by down-regulation of activity of At4g24160 or a homolog thereof. Plants, plant parts, seeds comprising down-regulated AT4G24160 activity, or activity of a homolog thereof, are also provided, as well as products prepared therefrom.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: August 13, 2013
    Assignees: University of North Texas, The Board of Regents of the University of Texas System
    Inventors: Kent D. Chapman, Richard G. W. Anderson
  • Liquid cooled stirling engine with a segmented rotary displacer
    Patent number: 8495873
    Abstract: The present invention provides a Stirling engine employing a segmented, rotary displacer for producing mechanical energy from a heat source. The engine includes a rotor shaft rotatably positioned in the interior toroidal cavity with a segmented displacer mounted to the rotor shaft within the interior toroidal cavity.
    Type: Grant
    Filed: September 16, 2010
    Date of Patent: July 30, 2013
    Assignee: University of North Texas
    Inventor: Phillip R. Foster
  • MONOLITHIC, FIBER-TO-FIBER COUPLED NONLINEAR RESONATOR FOR BREWSTER CUT PERIODICALLY POLED CRYSTALS
    Publication number: 20130156054
    Abstract: An apparatus and method for nonlinear conversion of laser light is described herein. The apparatus of the instant invention comprises a fiber coupled light source, a cavity in optical alignment with the first light beam from the light source, wherein the cavity comprises: two concave mirrors, one or more Brewster-cut periodically poled crystals, and a cavity servo to lock the length of cavity to laser frequency. In one aspect of the present invention the feedback to the lock is S-polarized component of first laser light reflected off the Brewster surface of nonlinear crystal.
    Type: Application
    Filed: August 5, 2011
    Publication date: June 20, 2013
    Applicant: University of North Texas System
    Inventor: University of North Texas System
  • Multinetwork nerve cell assay platform with parallel recording capability
    Patent number: 8460921
    Abstract: A neuronal network analysis plate having alternating rows of recording wells and amplifying wells. The recording wells contain a neural cell network and a series of electrodes for recording the action potential signals of the neurons. The electrodes are connected to amplifiers in adjacent amplifying wells. The close proximity of these amplifiers ideal because it permits the parallel, non-multiplexed recording of action potential signals from multiple different active nerve cell networks. The amplifiers in the amplifying wells can then be connected to external amplification equipment. The neuronal network analysis plate may be contained within a single commercially available 24 or 96 well plate. The neuronal network analysis plate can be used to detect and quantify pharmacological and toxicological responses of the neural cells to one or more agents in vitro.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: June 11, 2013
    Assignee: University of North Texas
    Inventor: Guenter W. Gross
  • MtNIP REGULATED PLANTS WITH SIGNIFICANTLY INCREASED SIZE AND BIOMASS
    Publication number: 20130145498
    Abstract: A composition and method for producing plants with increased biomass and growth characteristics, and plants which flower early relative to wild-type plants. The MtNIP gene is over-expressed in plants to increase biomass, growth, and early flowering.
    Type: Application
    Filed: November 2, 2012
    Publication date: June 6, 2013
    Applicant: UNIVERSITY OF NORTH TEXAS
    Inventor: University of North Texas
  • ANTI-FRETTING WEAR COATING FOR SUBSTRATES
    Publication number: 20130130014
    Abstract: A method and chemical composition and material structure for improving fretting wear in substrates, particularly carbon-carbon composite (CCC). The invention relates to trilayer coatings, comprising a base of hard ZrO2, a middle layer of Al2O3, and atop layer of lubricious ZnO. The coatings of the present invention exhibit conformality and pore-filling down to approximately 100 microns into a carbon-carbon composite to which they are applied. The methods for preparing the coatings include a chemical vapor infiltration route, such as an atomic layer deposition (ALD) process, to uniformly and conformally coat the porous and open structure of CCC with a solid lubricant trilayer of ZnO/Al2O3/ZrO2 that results in significant improvement (65%) in fretting wear.
    Type: Application
    Filed: May 18, 2012
    Publication date: May 23, 2013
    Applicant: The University of North Texas
    Inventors: Thomas W. Scharf, Hamidreza Mohseni, Jaimie S. Tiley
  • System, method and apparatus for energizing vehicle brake lights
    Patent number: 8441347
    Abstract: The present invention provides system, method and apparatus for energizing one or more brake lights on a vehicle without an operator of the vehicle applying a brake of the vehicle by determining an acceleration of the vehicle, energizing the brake lights on the vehicle whenever the acceleration of the vehicle equals or exceeds a braking threshold, and deenergizing the brake lights on the vehicle whenever: (a) the brake lights are energized, (b) the acceleration of the vehicle is less than the braking threshold, (c) a specified period of time has elapsed since the brake lights were energized, and (d) the operator is not applying the brake of the vehicle.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: May 14, 2013
    Assignee: University of North Texas System
    Inventors: Kenneth Adam Marlowe, Bryan Cotanch, James Parker
  • METHODS AND DEVICES FOR ELECTROMAGNETICALLY TUNING ACOUSTIC MEDIA
    Publication number: 20130112496
    Abstract: An acoustic material can be electromagnetically tuned to produce alterations in its acoustical properties without physical contact. The acoustic material should contain a periodic structure and a medium that has acousto-elastical properties that can be altered through the application of electromagnetic radiation. Changes in volumetric properties such as density result in changes to the velocity at which sound passes through the material. The acoustic material can be a phononic crystal that undergoes a change in its acoustic bandgap after being subjected to electromagnetic radiation. This electromagnetic tuning ability results in the ability to change the acoustic properties of various phononic devices without physical contact.
    Type: Application
    Filed: May 2, 2012
    Publication date: May 9, 2013
    Applicant: The University of North Texas
    Inventors: Arup Neogi, Ezekiel Walker
  • Apparatus and method for transmitting secure and/or copyrighted digital video broadcasting data over internet protocol network
    Patent number: 8423778
    Abstract: A content distribution method for video copyright authentication and security comprising the steps of invisibly watermarking digital video data input from a video data source to create watermarked data; encrypting the watermarked digital video data using an encryption key to create encrypted video data; sending the encrypted watermarked digital data and a decryption key to a distribution network; decrypting the encrypted watermarked digital data to generate video data and adding visible watermarking data to the video data to generate visibly encrypted watermarked data compressing the visibly encrypted watermarked data to create compressed data; sending said compressed data and to an end user receiver; decompressing the compressed data at the receiver to generate decompressed data; and displaying the decompressed data to an end user.
    Type: Grant
    Filed: November 19, 2008
    Date of Patent: April 16, 2013
    Assignee: University of North Texas
    Inventor: Saraju P. Mohanty
  • Fluorinated metal-organic frameworks for gas storage
    Patent number: 8343260
    Abstract: Fluorinated metal-organic frameworks (“FMOFs”) are capable of adsorbing and desorbing gases and molecules. The FMOFs can be arranged in a variety of configurations and have internal hollow channels and cavities. In the FMOFs, hydrogen atoms have been substituted completely or partially with fluorine atoms or fluorinated groups in each linking organic ligand. The FMOFs have high densities, leading to an enhanced volumetric capacity for gas storage.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: January 1, 2013
    Assignee: University of North Texas
    Inventors: Mohammad A. Omary, Chi Yang