Patents Assigned to The University of Reading
  • DNA encoding CRF binding protein
    Patent number: 5464757
    Abstract: A Corticotropin Releasing Factor-binding protein (CRF-BP) is isolated and purified sufficient to provide AA sequence data from which the DNA is obtained, which is then used to produce the protein recombinantly. The CRF-BP is useful for modulating the biological activity of CRF, such as reducing the high ACTH levels in mammals caused by excess CRF. The CRF-BP or fragments thereof and/or antibodies to the proteins may be employed in diagnostic assays to determine the levels of CRF, CRF-BP and the ratio of CRF/CRF-BP in a vascular fluid sample. The DNA or subsequence thereof can be used as probes for genetic material in certain assays. The anti-CRF-BP antibodies are also useful to purify the CRF-BP protein and to modulate the biological effect of CRF-BPs proteins.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: November 7, 1995
    Assignees: The Salk Institute for Biological Studies, University of Reading
    Inventors: Ellen Potter, Dominic P. Behan, Wolfgang H. Fischer, Elizabeth A. Linton, Philip J. Lowry, Wylie W. Vale, Jr.
  • Treatment of hair
    Patent number: 4853215
    Abstract: Hair is reconfigured by treatment with a composition comprising an enzyme (protein disulphide isomerase) and a cofactor therefor.
    Type: Grant
    Filed: November 4, 1987
    Date of Patent: August 1, 1989
    Assignee: University of Reading of Whiteknights House
    Inventor: Barbars E. Brockway
  • Treatment of wool materials
    Patent number: 4834765
    Abstract: A process and composition for treating a material comprising wool to ameliorate ageing, mis-shaping and shrinkage employ an enzyme (protein disulphide isomerase) and a cofactor therefor.
    Type: Grant
    Filed: November 4, 1987
    Date of Patent: May 30, 1989
    Assignee: The University of Reading of Whiteknights House
    Inventors: Richard D. King, Barbara E. Brockway