Patents Assigned to The University of Tokyo
  • Publication number: 20200165687
    Abstract: It is an object of the present invention to provide a method for easily detecting a transcript resulting from a fusion gene and/or exon skipping. In one embodiment, the present invention relates to a probe set for determining the presence or expression level of a transcript of a fusion gene on the genome, a probe set for determining the presence or expression level of a transcript resulting from exon skipping, a kit comprising the probe set, a method for determining the presence or expression level of a transcript of a fusion gene on the genome by using the probe set, and a method for determining the presence or expression level of a transcript resulting from exon skipping.
    Type: Application
    Filed: June 22, 2018
    Publication date: May 28, 2020
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Hiroyuki MANO, Shinji KOHSAKA, Toshihide UENO
  • Publication number: 20200159893
    Abstract: A scenario including a combination of procedures of multi-factor authentication required for a terminal to receive provision of a service is stored and managed in association with the service, and a probability that the procedure will succeed is stored and managed in association with each of the procedures, a success probability of the service through the scenario, is calculated based on the probability regarding the procedure to evaluate at least one of security and usability based on the success probability, and the service to the terminal, is controlled according to the evaluation result.
    Type: Application
    Filed: January 23, 2020
    Publication date: May 21, 2020
    Applicants: NEC Corporation, The University of Tokyo
    Inventors: Shizuo SAKAMOTO, Rie YAMAGUCHI, Hiroya SUSUKI
  • Publication number: 20200158620
    Abstract: A size reduction in an optical system that detects a fluorescent photon is achieved. A photon detection operation of a photon detection unit (21) is controlled on the basis of timing of an irradiation operation of an excitation light source (50), and after excitation light emitted to a microfluidic channel (10) is switched off, a fluorescent photon generated by a target flowing in the microfluidic channel (10) is detected.
    Type: Application
    Filed: June 5, 2018
    Publication date: May 21, 2020
    Applicants: SHARP KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, THE UNIVERSITY OF TOKYO
    Inventors: KUNIHIKO IIZUKA, YOSHIHISA FUJIMOTO, TAKESHI MITSUNAKA, TERUO FUJII, SOO-HYEON KIM
  • Patent number: 10658706
    Abstract: An electrolytic solution for a power storage device, the electrolytic solution containing water as a solvent, wherein an amount of the solvent is greater than 4 mol and not greater than 15 mol with respect to 1 mol of an alkali metal salt.
    Type: Grant
    Filed: January 6, 2017
    Date of Patent: May 19, 2020
    Assignees: THE UNIVERSITY OF TOKYO, KABUSHIKI KAISHA TOYOTA JIDOSHOKKI
    Inventors: Atsuo Yamada, Yuki Yamada, Kenji Usui, Junichi Niwa, Tomoyuki Kawai
  • Patent number: 10659743
    Abstract: An image projection device includes: a first mirror oscillating to scan an image light beam forming an image projected onto a retina of a user; a light source emitting the image light beam and a detection light beam to the first mirror at different timings; a second mirror having a first region reflecting the image light beam reflected by the first mirror to the retina and a second region reflecting the detection light beam reflected by the first mirror in a direction different from a direction in which the image light beam is reflected, and scanning neither the image light beam nor the detection light beam reflected by the first mirror; a detector detecting the detection light beam reflected by the second region; and a controller adjusting oscillation of the first mirror and an emission timing of the image light beam based on a detection result by the detector.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: May 19, 2020
    Assignees: QD LASER, INC., THE UNIVERSITY OF TOKYO
    Inventors: Yasuhiko Arakawa, Mitsuru Sugawara, Makoto Suzuki, Shuichi Tojo
  • Publication number: 20200149041
    Abstract: The present invention relates to a guide RNA molecule that hybridizes with a target sequence containing a mutation site of a transforming growth factor ?-induced (TGFBI) gene associated with granular corneal degeneration.
    Type: Application
    Filed: June 7, 2018
    Publication date: May 14, 2020
    Applicants: The University of Tokyo, National University Corporation Chiba University
    Inventors: Tomohiko Usui, Yukako Taketani, Yasuo Ouchi
  • Publication number: 20200150022
    Abstract: A cell evaluation system includes physical measurement unit, a database, and evaluation unit. The evaluation unit refers to a relevance stored in the database, searches reference measurement information based on measurement information of a cell newly measured via the physical measurement unit, and evaluates the cell with biological measurement information associated with the searched reference measurement information.
    Type: Application
    Filed: May 2, 2018
    Publication date: May 14, 2020
    Applicants: THINKCYTE, INC., The University of Tokyo
    Inventors: Masashi UGAWA, Yoko KAWAMURA, Sadao OTA
  • Publication number: 20200146592
    Abstract: A foot sole pressure measurement instrument includes a measurement unit which is installed on a foot sole part of a subject and measures a pressure applied to the foot sole part of the subject, and an output unit configured to output data of the measured pressure.
    Type: Application
    Filed: August 13, 2018
    Publication date: May 14, 2020
    Applicants: NIPPON TELEGRAPH AND TELEPHONE CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Shingo TSUKADA, Hiroshi NAKASHIMA, Nahoko KASAI, Hideo HATTA
  • Publication number: 20200149096
    Abstract: An object is to provide a method of eliminating background amplification in detection of rare nucleic acids based on isothermal amplification. The method comprising steps of: preparing a mixture including solution and enzymes, and adding a first and a second template into the mixture, wherein the first template is an amplification template, and the second template is a leak absorption template. Methods to use this approach for multiplexed, ultrasensitive and ultra-specific detection of nucleic acids are presented.
    Type: Application
    Filed: February 16, 2017
    Publication date: May 14, 2020
    Applicants: THE UNIVERSITY OF TOKYO, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Yannick RONDELEZ, Guillaume GINES, Kevin MONTAGNE, Teruo FUJII
  • Patent number: 10649519
    Abstract: A computer system includes: a database server configured to execute a database management system; and a storage apparatus configured to store data. The storage apparatus is configured to have a power saving function for switching between a sleep mode for reducing power consumption of the storage apparatus and an active mode for enabling read and write of the data. The database management system is configured to be executed by the arithmetic device, to thereby: receive a query for reading or writing data; analyze the received query to create an execution plan; identify a volume for reading and writing data; and select an execution plan for which power consumption satisfies a predetermined threshold value based on power consumption information on the identified volume.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: May 12, 2020
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Kazuo Goda, Masaru Kitsuregawa
  • Patent number: 10650173
    Abstract: A design support apparatus supporting designing of a product which uses a fiber material includes a processor that creates a predicted shape model by predicting a shape of the product before a deformation processing. The processor: creates a 3-dimensional shape model of the product; creates curved shape models by separating the 3-dimensional shape model into two or more fiber layers; sets a correspondence relationship between the curved shape models; creates an orientation vector field in the curved shape models; and predicts the shape of the product before the deformation processing by developing the curved shape models on a flat surface based on the correspondence relationship between the curved shape models and the orientation vector field in the curved shape models, and creates the predicted shape model based on the predicted shape.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: May 12, 2020
    Assignees: IHI CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Hiroyuki Hishida, Koichi Inagaki, Takeshi Nakamura, Fumiaki Watanabe, Kotaro Morioka, Yutaka Ohtake, Hiromasa Suzuki, Yukie Nagai
  • Patent number: 10645912
    Abstract: [Problem to be Solved] The present invention provides a method for producing a chimeric animal using a primed pluripotent stem cell, a tissue stem cell, a progenitor cell, a somatic cell, or a germ cell. [Solution] The method for producing a chimeric animal according to the present invention comprises introducing a mammal-derived cell into the embryo of a mammal, the cell being primed pluripotent stem cell, tissue stem cell, progenitor cell, somatic cell, or germ cell.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: May 12, 2020
    Assignees: THE UNIVERSITY OF TOKYO, THE BOARD OF REGENTS OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Hiromitsu Nakauchi, Hideki Masaki, Motoo Watanabe, Irving Weissman
  • Patent number: 10651400
    Abstract: Objects of the present invention is to provide an organic semiconductor element having high mobility and to provide a composition for forming an organic semiconductor film with which an organic semiconductor film having high mobility can be formed, a method of manufacturing an organic semiconductor element formed from the composition for forming an organic semiconductor film, and a method of manufacturing an organic semiconductor film. The organic semiconductor element according to the present invention has a semiconductor active layer including a compound that is represented by Formula 1 and has a molecular weight of 3,000 or less. The composition for forming an organic semiconductor film according to the present invention contains a compound that is represented by Formula 1 and has a molecular weight of 3,000 or less, and a solvent.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: May 12, 2020
    Assignees: FUJIFILM CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Hiroaki Tsuyama, Yoshihisa Usami, Toshihiro Okamoto, Junichi Takeya
  • Patent number: 10643631
    Abstract: The present invention reduces encoding distortion in frequency domain encoding compared to conventional techniques, and obtains LSP parameters that correspond to quantized LSP parameters for the preceding frame and are to be used in time domain encoding from coefficients equivalent to linear prediction coefficients resulting from frequency domain encoding. When p is an integer equal to or greater than 1, a linear prediction coefficient sequence which is obtained by linear prediction analysis of audio signals in a predetermined time segment is represented as a[1], a[2], . . . , a[p], and ?[1], ?[2], . . . , ?[p] are a frequency domain parameter sequence derived from the linear prediction coefficient sequence a[1], a[2], . . . , a[p], an LSP linear transformation unit (300) determines the value of each converted frequency domain parameter ˜?[i] (i=1, 2, . . . , p) in a converted frequency domain parameter sequence ˜?[1], ˜?[2], . . . , ˜?[p] using the frequency domain parameter sequence ?[1], ?[2], . . .
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: May 5, 2020
    Assignees: Nippon Telegraph and Telephone Corporation, The University of Tokyo
    Inventors: Takehiro Moriya, Yutaka Kamamoto, Noboru Harada, Hirokazu Kameoka, Ryosuke Sugiura
  • Publication number: 20200131562
    Abstract: The present invention provides a method for integrally detecting nondestructive measurement information and genome-related information of single cells. More specifically, the present invention uses a method including: preparing a plurality of compartments containing single cell or a derivative thereof, a first bead(s), and a second bead(s) per compartment; detecting both nondestructive measurement information of single cell and imaging information of the first bead(s) and associating the nondestructive measurement information of single cell with the imaging information of the first bead(s) before preparation of each compartment or in each compartment; obtaining a hybridized complex; producing an amplified product derived from the hybridized complex; and integrally detecting nondestructive measurement information and genome-related information in single cell.
    Type: Application
    Filed: May 2, 2018
    Publication date: April 30, 2020
    Applicant: The University of Tokyo
    Inventors: Nozomu YACHIE, Sadao OTA
  • Patent number: 10633249
    Abstract: A method for simultaneously producing carbon nanotubes and hydrogen according to the present invention is a method for simultaneously producing carbon nanotubes and hydrogen, in which using a carbon source containing carbon atoms and hydrogen atoms and being decomposed in a heated state, and a catalyst for producing carbon nanotubes and H2 from the carbon source, the above carbon nanotubes are synthesized on a support in a heated state, placed in a reactor, and simultaneously, the above H2 is synthesized from the above carbon source, the method comprising a synthesis step of flowing a source gas comprising the above carbon source over the above support, on which the above catalyst is supported, to synthesize the above carbon nanotubes on the above support and simultaneously synthesize the above H2 in a gas flow.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: April 28, 2020
    Assignees: The University of Tokyo, Hitachi Chemical Company, Ltd.
    Inventors: Suguru Noda, Dong Young Kim, Toshio Osawa, Hisashi Sugime, Kei Hasegawa, Eisuke Haba
  • Patent number: 10631722
    Abstract: A probability distribution of visual sensitivities at each visual target presentation position of the subject is inferred on the basis of the test result information which is visual sensitivity information at each of the visual target presentation positions obtained through the tests performed in the past. Input of visual sensitivity information of the subject at at least one presentation position among the plurality of visual target presentation positions is received. Mutual information between visual sensitivity information of the subject regarding the visual test target represented by the received information and visual sensitivity information regarding each visual test target for which no visual sensitivity information of subject has been input, using the inferred probability distribution, is calculated, and the calculated mutual information is provided for a predetermined process for selecting a position at which the next visual test target is to be presented.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: April 28, 2020
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Ryo Asaoka, Hiroshi Murata
  • Patent number: 10636833
    Abstract: A quantum dot infrared detector includes a quantum dot-stacked structure in which quantum dot layers each containing quantum dots stacked on top of one another and intermediate layers. The quantum dots are sandwiched between the intermediate layers in the height direction of the quantum dots. The quantum dots have conduction band quantum confinement levels that include a conduction band ground level, a conduction band first excitation level at a higher energy position than the conduction band ground level, and a conduction band second excitation level at a higher energy position than the conduction band ground level. An energy gap between the conduction band first excitation level and the conduction band bottom of the intermediate layer and an energy gap between the conduction band second excitation level and the conduction band bottom of the intermediate layer are each smaller than twice thermal energy.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: April 28, 2020
    Assignees: SHARP KABUSHIKI KAISHA, The University of Tokyo
    Inventors: Hirofumi Yoshikawa, Yasuhiko Arakawa
  • Publication number: 20200122318
    Abstract: A control system according to an embodiment includes a motor configured to drive a link, a first sensor configured to detect information about the driving by the motor or information about a relation between the driving means and the load member as first sensor information, a second sensor configured to detect information about a displacement of the link as second sensor information, and a control unit configured to perform feedback control of the driving means so as to follow a command value in a two-inertial system model including an inertial system on a load side and an inertial system on a driving side. The control unit includes a disturbance observer configured to estimate a disturbance, and a filter configured to convert an estimated value of the disturbance into a driving force of the motor.
    Type: Application
    Filed: October 17, 2019
    Publication date: April 23, 2020
    Applicants: The University of Tokyo, Toyota Jidosha Kabushiki Kaisha
    Inventors: Hiroshi Fujimoto, Akiyuki Hasegawa, Taro Takahashi
  • Patent number: 10624991
    Abstract: The method for producing a three-dimensional artificial tissue is a method in which a three-dimensional artificial tissue extending in a predetermined direction is produced. The method includes: preparing a device including a culture tank having a culturing space surrounded by sidewalls, and a flow channel-forming member that penetrates through the sidewalls that face each other and is suspended in the culturing space along a predetermined direction; culturing cells in the culturing space and thereby forming a three-dimensional artificial tissue through which the flow channel-forming member penetrates; and removing the flow channel-forming member from the three-dimensional artificial tissue and thereby forming a perfusion flow channel that penetrates through the three-dimensional artificial tissue.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: April 21, 2020
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Shoji Takeuchi, Yuya Morimoto, Nobuhito Mori