Patents Assigned to The University of Tokyo
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Publication number: 20250144759Abstract: To accurately perform movement control of a moving body, a machine tool includes a feed driver that moves a moving body in the machine tool, a feedback controller that feedback-controls the feed driver in accordance with a state variable, a friction compensator that, to compensate for rolling friction that occurs in the feed driver, adds, in advance, a friction compensation value obtained from measurement data of rolling friction or a friction compensation value calculated using a rolling friction model to a command value to be input to the feed driver, and a reverse response reducer that reduces, using the state variable of the feedback controller, a reverse response that occurs due to addition of the friction compensation value.Type: ApplicationFiled: December 27, 2022Publication date: May 8, 2025Applicants: The University of Tokyo, DMG MORI CO., LTDInventors: Hiroshi FUJIMOTO, Takumi HAYASHI, Yuki TERADA, Yoshihiro ISAOKA
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Publication number: 20250135433Abstract: [Object] To suppress a decrease in the adsorption performance of an adsorbent containing diatomaceous earth and a basic compound. [Solution] An adsorbent for adsorbing an acid gas contains diatomaceous earth, a basic compound, and a saccharide.Type: ApplicationFiled: September 27, 2022Publication date: May 1, 2025Applicants: DAIKIN INDUSTRIES, LTD., The University of TokyoInventors: Takuya MATSUOKA, Mayu NISHIMURA, Ichiro SAKATA, Bunshi FUGETSU, Vipin ADAVAN KILIYANKIL, Takayuki UEKI
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Patent number: 12286650Abstract: The purpose of the present invention is to provide a set of two polypeptides for use in light-dependent genetic recombination in which the N-terminal side fragment and the C-terminal side fragment of a Cre protein having an amino acid sequence of SEQ ID NO: 1 respectively bind to two proteins light-dependently forming a dimer.Type: GrantFiled: April 10, 2018Date of Patent: April 29, 2025Assignee: The University of TokyoInventor: Moritoshi Sato
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Publication number: 20250117963Abstract: A people flow control evaluation apparatus (100) evaluates an effect of people flow control. A position obtaining unit (110) extracts a position of a target person chronologically from people flow information (20) and stores the position of the target person as chronological position information (41). A direction calculation unit (120) calculates a movement direction of the target person chronologically based on the chronological position information (41) and stores the movement direction of the target person as a chronological movement direction (42). An effect evaluation unit (130) calculates an angular difference between the movement direction of the target person and a direction towards a destination position from the position of the target person chronologically, and evaluates the effect of the people flow control using a chronological change of the angular difference calculated chronologically.Type: ApplicationFiled: December 18, 2024Publication date: April 10, 2025Applicants: Mitsubishi Electric Corporation, The University of TokyoInventors: Hirofumi NISHIKAWA, Katsuhiro NISHINARI
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Publication number: 20250110346Abstract: A polarization splitting device includes a substrate, and a polarization splitting layer having a structure element pattern including a plurality of structure elements each having two-fold rotational symmetry, and formed on an upper surface of the substrate. The polarization splitting layer splits first to sixth polarization components included in object light, and focuses respectively at first to sixth focal positions on a focal plane. The structure element pattern includes a first structure element pattern for focusing the first and second polarization components, a second structure element pattern for focusing the third and fourth polarization components, and a third structure element pattern for focusing the fifth and sixth polarization components, and a pattern constituted by a first structure element, a second structure element, and a third structure element is set as a unit pattern, and a plurality of unit patterns are two-dimensionally arranged.Type: ApplicationFiled: January 26, 2023Publication date: April 3, 2025Applicants: HAMAMATSU PHOTONICS K.K., The University of TokyoInventors: Go SOMA, Yoshiro NOMOTO, Yoshiaki NAKANO, Takuo TANEMURA
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Publication number: 20250102165Abstract: An air conditioning system (1) includes a carbon dioxide separation device (20) configured to separate some or all of carbon dioxide from air that contains carbon dioxide, an electrolytic reduction device (30) configured to generate a hydrocarbon and oxygen using the separated carbon dioxide as a raw material, and an oxygen supply amount control device (40) configured to supply some or all of the oxygen generated by the electrolytic reduction device (30) to a space to be processed (10).Type: ApplicationFiled: March 7, 2023Publication date: March 27, 2025Applicants: The University of Tokyo, CHIYODA CORPORATION, SHIMIZU CORPORATIONInventors: Hiroji EBE, Masakazu SUGIYAMA, Jun MATSUMOTO, Dai TAKEDA, Ittetsu OBA, Shinya HASHIMOTO, Yukinori FUSE, Mitsuhiro SUMIKURA, Yoshito ARAI
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Patent number: 12258557Abstract: A mammalian or avian cell line that expresses high levels of human influenza virus receptors is provided. In one embodiment, the cell line supports human influenza virus, e.g., human A/H3 influenza virus, isolation and growth much more effectively than corresponding conventional (unmodified) cells or in corresponding human virus receptor-overexpressing cells, and the propagated viruses may maintain higher genetic stability than in the corresponding cells.Type: GrantFiled: November 30, 2023Date of Patent: March 25, 2025Assignees: Wisconsin Alumni Research Foundation (WARF), The University of TokyoInventors: Yoshihiro Kawaoka, Kosuke Takada, Masaki Imai
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Patent number: 12251436Abstract: Modified influenza virus neuraminidases are described herein that improve viral replication, thus improving the yield of vaccine viruses. Expression of such modified. neuraminidases by influenza virus may also stabilize co-expressed hemagglutinins so that the hemagglutinins do not undergo mutation.Type: GrantFiled: December 9, 2021Date of Patent: March 18, 2025Assignees: Wisconsin Alumni Research Foundation (WARF), The University of TokyoInventors: Yoshihiro Kawaoka, Shinya Yamada, Shiho Chiba
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Publication number: 20250065750Abstract: A power supply apparatus includes a power reception coil mounted to a moving object, a plurality of relay coils, and a power reception circuit connected with the power reception coil. The relay coils are configured to successively relay supply of electric power from a power transmission coil, which is arranged along a surface on which the moving object moves, to the power reception coil during movement of the moving object. Each of the relay coils includes a first coil and a second coil, which are configured to be magnetic-field-coupled respectively to the power transmission coil and the power reception coil, and a connection circuit that connects the first and second coils. The connection circuit includes at least one resonance capacitor involved in setting of a resonance frequency of at least one of the first and second coils. The at least one resonance capacitor has a parallel characteristic.Type: ApplicationFiled: November 14, 2024Publication date: February 27, 2025Applicants: DENSO CORPORATION, The University of TokyoInventors: Hayato SUMIYA, Eisuke TAKAHASHI, Nobuhisa YAMAGUCHI, Hiroshi FUJIMOTO, Osamu SHIMIZU
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Patent number: 12237346Abstract: According to an aspect, a detection device includes a plurality of optical sensors arranged on a substrate. Each of the optical sensors includes a first photodiode and a second photodiode that is coupled in series and in an opposite direction to the first photodiode.Type: GrantFiled: July 25, 2023Date of Patent: February 25, 2025Assignees: Japan Display Inc., The University of TokyoInventors: Keiichi Saito, Takashi Nakamura, Gen Koide, Takao Someya, Tomoyuki Yokota
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Patent number: 12227642Abstract: An object of the present invention is to provide a gel material including a solvophilic polymer having a ?m-scale porous structure. A polymer gel in which solvophilic polymer units are cross-linked with each other, wherein the polymer gel contains a solvent and has a three-dimensional network structure having two regions: a first region in which the polymer units are densely present and a second region in which the polymer units are sparsely present, and a mesh size composed of the first region is from 1 to 500 ?m.Type: GrantFiled: July 29, 2019Date of Patent: February 18, 2025Assignee: The University of TokyoInventors: Takamasa Sakai, Yuichi Tei
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Patent number: 12230023Abstract: An analysis device includes an analysis unit configured to receive scattered light, transmitted light, fluorescence, or electromagnetic waves from an observed object located in a light irradiation region light-irradiated from a light source and analyze the observed object on the basis of a signal extracted on the basis of a time axis of an electrical signal output from a light-receiving unit configured to convert the received light or electromagnetic waves into the electrical signal.Type: GrantFiled: November 16, 2023Date of Patent: February 18, 2025Assignees: The University of Tokyo, Osaka UniversityInventors: Sadao Ota, Issei Sato, Katsuhito Fujiu, Satoko Yamaguchi, Kayo Waki, Yoko Itahashi, Ryoichi Horisaki
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Publication number: 20250049735Abstract: It is an object of the present invention to provide a preventive agent, a therapeutic agent or a therapeutic composition for steatohepatitis developed by phospholipid deficiency or decreased phospholipid synthesis in the liver, and to provide a therapeutic method for the aforementioned disease. More specifically, the present invention relates to a therapeutic agent for steatohepatitis, comprising, as an active ingredient, choline or a choline metabolite, ethanolamine or an ethanolamine metabolite, a salt thereof, or a solvate thereof, wherein the therapeutic agent for steatohepatitis is characterized in that the steatohepatitis is developed by decreased phospholipid synthesis in the liver. Examples of the choline metabolite may include betaine, dimethylglycine, and phosphatidylcholine.Type: ApplicationFiled: December 5, 2022Publication date: February 13, 2025Applicant: The University of TokyoInventors: Hisamitsu HAYASHI, Yusuke SABU, Ryutaro TAMURA
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Patent number: 12221649Abstract: A compound is represented by the following general formula (I): The compound or a salt thereof provides a fluorescent probe for detecting carboxypeptidase activity In the formula, R1 represents an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; T represents an amino acid residue or a residue of an amino acid derivative; S represents a C-terminal amino acid residue. represents a fluorophore, and the fluorophore is a fluorophore in which an absorption/fluorescence wavelength greatly changes or a quenched state changes to a fluorescent state by elimination of the —P(?O)(—R1)-T-S moiety.Type: GrantFiled: December 2, 2019Date of Patent: February 11, 2025Assignee: The University of TokyoInventors: Yasuteru Urano, Mako Kamiya, Yugo Kuriki
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Patent number: 12214003Abstract: It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.Type: GrantFiled: May 28, 2024Date of Patent: February 4, 2025Assignee: The University of TokyoInventors: Kenya Honda, Koji Atarashi, Kikuji Itoh, Takeshi Tanoue
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Patent number: 12215019Abstract: An electrostatic device includes: a fixed portion, a moveable portion, and an elastically-supporting portion that are formed in a same substrate; and a first glass package and a second glass package that are anodically bonded to each other on one and the other of front and back surfaces of the substrate with the fixed portion and the elastically-supporting portion separated from each other, the second glass package forms a sealed space in which the moveable portion is arranged between the first and second glass packages, an electret is formed at least partially in the fixed portion and the moveable portion, and a first electrode connected to the fixed portion and exposed on an outer surface of the second glass package and a second electrode connected to the elastically-supporting portion and exposed on the outer surface of the second glass package are formed in the second glass package.Type: GrantFiled: March 19, 2020Date of Patent: February 4, 2025Assignees: The University of Tokyo, Saginomiya Seisakusho, Inc.Inventors: Hiroshi Toshiyoshi, Hiroaki Honma, Hiroyuki Mitsuya
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Publication number: 20250034338Abstract: Provided are: cellulose porous particles which have large surface areas on which cells can be attached, and on which cells can be adhered easily, and which rarely undergo the detachment of cells when the cells are cultured at a high density; and a microcarrier for culture use, which comprises the cellulose porous particles. The cellulose porous particles according to the present invention are composed of cellulose, in which the cellulose constituting the cellulose porous particles is modified by a cationic substituent and the cellulose constituting the celluose porous particles has a polypeptide bound thereto.Type: ApplicationFiled: December 8, 2022Publication date: January 30, 2025Applicants: The University of Tokyo, ASAHI KASEI KABUSHIKI KAISHAInventors: Yuichi Hara, Kodai Harano, Ayae Sano, Taichi Ito, Yuichiro Oki, Natsuko Inagaki
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Publication number: 20250032681Abstract: The purpose of this invention is to provide an anti-adhesion material having a high anti-adhesion effect, pertaining to an anti-adhesion material comprising a biocompatible sponge-like layered body having a sponge-like first layer and a sponge-like second layer both being at least partially crosslinked with a curing agent and comprising a low endotoxin monovalent metal salt of alginic acid. The monovalent metal salt of alginic acid in the first layer has a weight average molecular weight of 30000 to 300000. The monovalent metal salt of alginic acid in the second layer has a weight average molecular weight of 1000 to 200000. The weight average molecular weights are determined by GPC-MALS after a de-crosslinking treatment. The weight average molecular weight of the monovalent metal salt of alginic acid in the first layer is higher than the weight average molecular weight of the monovalent metal salt of alginic acid in the second layer.Type: ApplicationFiled: October 1, 2024Publication date: January 30, 2025Applicants: Mochida Pharmaceutical Co., Ltd., The University of TokyoInventors: Taichi ITO, Seiichi OHTA, Kiyoshi HASEGAWA, Mitsuko ISAJI, Satoshi SHIMIZU, Daichi TANAKA
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Patent number: 12213377Abstract: Provided are an organic thin film transistor, an organic semiconductor film, a compound, an organic thin film transistor-forming composition, and a method of manufacturing the organic thin film transistor. The organic thin film transistor includes the organic semiconductor film. The organic semiconductor film includes a compound represented by a specific formula. The organic semiconductor film, the compound, and the organic thin film transistor-forming composition can be preferably used in the organic thin film transistor. The method of manufacturing the organic thin film transistor includes a step of forming an organic semiconductor film by applying the organic thin film transistor-forming composition to a substrate.Type: GrantFiled: July 22, 2021Date of Patent: January 28, 2025Assignees: FUJIFILM Corporation, The University of TokyoInventors: Eiji Fukuzaki, Tetsuya Watanabe, Yoshihisa Usami, Yukio Tani, Toshihiro Okamoto, Junichi Takeya
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Publication number: 20250027096Abstract: The present disclosure provides a transformant obtained by introducing an aldehyde-alcohol dehydrogenase gene into a bacterium of the genus Hydrogenophilus.Type: ApplicationFiled: October 1, 2024Publication date: January 23, 2025Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii