Patents Assigned to The University of Tokyo
  • Publication number: 20220149666
    Abstract: A dynamic wireless power transfer system includes a power transmission coil, a power transmission circuit, a power reception coil, a power reception circuit, and a relay circuit. The power transmission coil is provided in a road. The power transmission circuit supplies electric power to the power transmission coil. The power reception coil is provided in a vehicle. The power reception circuit is connected to the power reception coil. The relay circuit transfers electric power between the power transmission coil and the power reception coil in a contactless manner.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 12, 2022
    Applicants: DENSO CORPORATION, The University of Tokyo
    Inventors: Hayato SUMIYA, Eisuke TAKAHASHI, Nobuhisa YAMAGUCHI, Masaya TAKAHASHI, Hiroshi FUJIMOTO, Osamu SHIMIZU
  • Patent number: 11325072
    Abstract: An object trapping device enables efficiently trapping a plurality of objects in a specific combination. Each of a first electrode pair (13), a second electrode pair (14), and a third electrode pair (15) in an electrode pair group (3) is applied with an individual AC voltage and traps an object by dielectrophoresis generated in accordance with the AC voltage that is applied.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 10, 2022
    Assignees: SHARP KABUSHIKI KAISHA, The University of Tokyo
    Inventors: Kunihiko Iizuka, Takeshi Mitsunaka, Yoshihisa Fujimoto, Teruo Fujii, Soo-Hyeon Kim
  • Patent number: 11324835
    Abstract: A unit-type polyion complex for use in delivering nucleic acid to a target site in a patient includes one or more molecules of a block copolymer having a poly(ethylene glycol) segment and a cationic poly(amino acid) segment and one or more molecules of a nucleic acid. A total quantity of positive charges derived from side chains of the cationic poly(amino acid) segment of the block copolymer in the unit-type polyion complex is not offset by a total quantity of negative charges derived from the nucleic acid. Furthermore, the nucleic acid has a strand length of 10-50 bases, the molecular weight of the poly(ethylene glycol) segment is 40×103 or more, and the block copolymer has a binding constant (Ka) for the nucleic acid of 3.0×105 or more.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: May 10, 2022
    Assignees: KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION, THE UNIVERSITY OF TOKYO
    Inventors: Kazunori Kataoka, Kanjiro Miyata, Shigeto Fukushima, Kotaro Hayashi, Sumiyo Watanabe, HyunJin Kim, Kazuko Toh
  • Patent number: 11326433
    Abstract: A fracturing method, to cause a crack in bedrock, includes installing a depressurizing device in a well in the bedrock, and depressurizing the inside of the well with the installed depressurizing device. The installing step includes installing, in the well, a connecting pipe, which is connected to the depressurizing device, and a packer, which is attached to the connecting pipe, and the depressurizing step includes shutting off a gap between the well and the connecting pipe, with the packer, and depressurizing a region in the well below the packer, with the depressurizing device.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: May 10, 2022
    Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITY, JMC GEOTHERMAL ENGINEERING CO., LTD., INPEX DRILLING CO., LTD.
    Inventors: Hiroshi Asanuma, Shigemi Naganawa, Noriyoshi Tsuchiya, Tatsuya Kajiwara, Kuniaki Shimada
  • Patent number: 11327002
    Abstract: A size reduction in an optical system that detects a fluorescent photon is achieved. A photon detection operation of a photon detection unit (21) is controlled on the basis of timing of an irradiation operation of an excitation light source (50), and after excitation light emitted to a microfluidic channel (10) is switched off, a fluorescent photon generated by a target flowing in the microfluidic channel (10) is detected.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: May 10, 2022
    Assignees: SHARP KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO
    Inventors: Kunihiko Iizuka, Yoshihisa Fujimoto, Takeshi Mitsunaka, Teruo Fujii, Soo-Hyeon Kim
  • Publication number: 20220135691
    Abstract: A therapeutic or prophylactic agent for radiation damage associated with radiation exposure, comprising an eosinophil-removing agent as an active ingredient and the like are provided as a technique for efficiently treating or preventing radiation damage associated with radiation exposure. According to the therapeutic or prophylactic agent comprising an eosinophil-removing agent according to the present invention, by suppressing migration and/or infiltration into target tissue and/or proliferation in the tissue of eosinophils and/or inhibiting the activity or function of the eosinophils, pathological conditions such as inflammatory responses and fibrosis of tissue can be suppressed to effectively treat or prevent radiation damage. Moreover, effective radiation therapy can be performed by suppressing radiation damage.
    Type: Application
    Filed: November 18, 2021
    Publication date: May 5, 2022
    Applicants: Kyowa Kirin Co., Ltd., The University of Tokyo
    Inventors: Kazuki OKADA, Kiyotoshi Mori, Satoshi Uematsu, Naoki Takemura
  • Patent number: 11321836
    Abstract: An image-processing device including: a determination unit that determines a captured image on the basis of a ratio of cells and a distribution of the cells in the captured image acquired by imaging a sample including cells; and an area setting unit that sets an area used for analyzing the cells of the sample on the basis of a result of the determination acquired by the determination unit.
    Type: Grant
    Filed: April 2, 2020
    Date of Patent: May 3, 2022
    Assignees: NIKON CORPORATION, THE UNIVERSITY OF TOKYO
    Inventors: Mamiko Masutani, Kenta Imai, Wataru Tomosugi, Takuro Saigo, Chisako Iwamoto, Masafumi Yamashita, Kenichi Ohba, Masayuki Murata, Fumi Kano, Yoshiyuki Noguchi
  • Patent number: 11312956
    Abstract: A nucleic acid which can inhibit expression of the MEX3B gene with low cytotoxicity as a side effect, an MEX3B gene expression inhibitor which contains said nucleic acid, a method for inhibiting MEX3B gene expression, and a prophylactic or therapeutic agent for disease caused by MEX3B gene expression are provided. This nucleic acid, which inhibits the expression of the MEX3B gene, is an antisense oligonucleotide having a sequence complementary to an oligonucleotide that contains at least 10 contiguous nucleotides in an untranslated region in an exon of the MEX3B gene, or a double-stranded RNA including at least 20 contiguous nucleotides in the aforementioned untranslated region, or DNA encoding said double-stranded RNA.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: April 26, 2022
    Assignees: TAK-CIRCULATOR CO., LTD, UNIVERSITY OF TOKYO
    Inventors: Tetsu Akiyama, Yusuke Yamazumi, Kazuyoshi Kofu
  • Patent number: 11315595
    Abstract: The present invention provides a recording method and a recording device in which information can be easily recorded even in a magnetic recording medium using epsilon iron oxide particles having a high coercive force as a magnetic recording material. A recording device of the invention applies an external magnetic field H0 that inclines magnetization of epsilon iron oxide particles to a particle dispersion element containing epsilon iron oxide particles, and irradiates the particle dispersion element with light that excites the magnetization. Accordingly, the recording device is capable of inverting magnetization that is not capable of being inverted only by the external magnetic field, in accordance with a synergetic effect between the inclination of the magnetization and the light excitation of the magnetization.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: April 26, 2022
    Assignees: THE UNIVERSITY OF TOKYO, OSAKA UNIVERSITY, FUJIFILM Corporation
    Inventors: Shin-ichi Ohkoshi, Makoto Nakajima, Masashi Shirata, Hiroaki Doshita
  • Publication number: 20220119768
    Abstract: Solutions to the problem of the invention are a method for selectively killing or removing a senescent cell, substance identification, and a method for purifying a senescent cell. Specifically, the invention includes an agent for removing a senescent cell, which is a drug for removing an in vivo senescent cell, the agent containing an inhibitor for glutaminase as an active ingredient, and a pharmaceutical composition containing the agent. The invention further includes a method for preparing a senescent cell, including the following steps (a) to (c): (a) synchronizing a cell with the G2 phase; (b) activating an intracellular p53 protein in the cell synchronized with the G2 phase; and (c) inhibiting polo-like kinase 1 (PLK1) activity in the cell treated in the step (b).
    Type: Application
    Filed: November 7, 2019
    Publication date: April 21, 2022
    Applicant: The University of Tokyo
    Inventors: Makoto NAKANISHI, Yoshikazu JOHMURA
  • Publication number: 20220120753
    Abstract: The present invention is intended to provide a method for determining the prognosis of a hormone receptor-positive cancer (for example, an ER?-positive breast cancer, an ER?-positive endometrial cancer, etc.) or a method for assisting the determination of the prognosis, and a method for evaluating the sensitivity of the cancer to antihormone therapy or a method for assisting the evaluation of the sensitivity of the cancer to antihormone therapy. Specifically, the present invention relates to a method for determining the prognosis of a hormone receptor-positive cancer, or a method for assisting the determination of the prognosis, which comprises the following steps (a) and (b): (a) a step of detecting Fbxo22-positive cancer cells in a sample derived from the cancer tissues; and (b) a step of calculating the percentage of the Fbxo22-positive cancer cells to the cells present in the sample.
    Type: Application
    Filed: September 20, 2019
    Publication date: April 21, 2022
    Applicants: The University of Tokyo, St. Marianna University School of Medicine
    Inventors: Makoto NAKANISHI, Yoshikazu JOHMURA, Tomohiko OHTA
  • Publication number: 20220119440
    Abstract: A peptide having a fluoroalkyl group as its side chain and a method for producing, which comprises condensing a compound represented by the formula (6-2) or (6-4), where means that an asymmetric carbon atom has an absolute configuration of S or R, Rf is a C1-30 alkyl group which is substituted with at least two fluorine atoms, and which may further be substituted with a halogen atom other than a fluorine atom (when the C1-30 alkyl group is a C2-30 alkyl group, it may have 1 to 5 etheric oxygen atoms between carbon atoms), and R2 is a protecting group for the amino group, with a fluorinated amino acid having its carboxy group protected, an amino acid having its carboxy group protected, a fluorinated peptide having its C-terminal protected, or a peptide having its C-terminal protected.
    Type: Application
    Filed: December 30, 2021
    Publication date: April 21, 2022
    Applicants: AGC Inc., THE UNIVERSITY OF TOKYO
    Inventors: Takashi OKAZOE, Yuichiro ISHIBASHI, Shinsuke SANDO, Jumpei MORIMOTO, Kohsuke AIKAWA, Toshiki MIKAMI, Takahiro ONO
  • Publication number: 20220119302
    Abstract: Provided is optical glass containing, in terms of mol % of cations: 10 to 60% of a La3+ component; more than 0% and up to 75% of a Ga3+ component; and 5 to 75% of a Nb5+ component, in which a total amount of the La3+ component, Ga3+ component, and Nb5+ component is 60 to 100%.
    Type: Application
    Filed: December 28, 2021
    Publication date: April 21, 2022
    Applicants: The University of Tokyo, NIKON CORPORATION
    Inventors: Hiroyuki INOUE, Atsunobu MASUNO, Kohei YOSHIMOTO, Motoi UEDA, Hiroshi YAMAMOTO, Tatsunori KAWASHIMA
  • Publication number: 20220120612
    Abstract: An optical property evaluation apparatus evaluates an optical property of an evaluation object, and includes a light source, a polarization beam splitter, a polarization adjuster, a first detector, a second detector, and an analyzer. The analyzer obtains a reflectance when linearly polarized light in a specific direction is incident on the evaluation object based on the detection result by the first detector when the light with which the evaluation object is irradiated is set to be the linearly polarized light in the specific direction. The analyzer obtains a phase property at the reflection of the evaluation object based on the detection result by the first detector or the second detector when the light with which the evaluation object is irradiated is set to have a polarization state different from the linearly polarized light in the specific direction, and a Jones matrix.
    Type: Application
    Filed: October 7, 2021
    Publication date: April 21, 2022
    Applicants: HAMAMATSU PHOTONICS K.K., The University of Tokyo
    Inventors: Yoshiro NOMOTO, Takuo TANEMURA
  • Patent number: 11307040
    Abstract: A map information provision system includes: a road map information database configured to store road map information; a vehicle position determination unit configured to detect and determine a position of a vehicle on a road; a road map information extraction unit configured to extract the road map information around the vehicle from the road map information database, based on the position of the vehicle; and a waypoint map constructor unit configured to determine positions of waypoints and configure a waypoint map that is made up of the plurality of the waypoints, wherein the waypoint map is supplied to a driving support device for the vehicle or a driving control device for the vehicle and is utilized as map information on the planned driving route.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: April 19, 2022
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, National University Corporation Tokyo University of Agriculture and Technology, SCHOOL JUDICIAL PERSON IKUTOKU GAKUEN
    Inventors: Kyoichi Tohriyama, Takuma Ito, Satoshi Nakamura, Minoru Kamata, Pongsathorn Raksincharoensak, Tsukasa Shimizu, Hideo Inoue
  • Patent number: 11308813
    Abstract: There is provided a flight management system for managing a flight plan of flying objects that fly among ports.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: April 19, 2022
    Assignees: The University of Tokyo, BLUE INNOVATION Co., Ltd.
    Inventors: Christopher Thomas Raabe, Shinji Suzuki, Takeshi Tsuchiya, Masayuki Kumada, Kazuya Sakai, Takashi Matsuo, Tsuyoshi Chiba
  • Publication number: 20220108468
    Abstract: The present invention provides a motion capture with a high accuracy which can replace an optical motion capture technology, without attaching optical markers and sensors to a subject. A subject with an articulated structure has a plurality of feature points in the body of the subject including a plurality of joints wherein a distance between adjacent feature points is obtained as a constant. A spatial distribution of a likelihood of a position of each feature point is obtained based on a single input image or a plurality of input images taken at the same time. One or a plurality of position candidates corresponding to each feature point are obtained based on the spatial distribution of the likelihood of the position of each feature point. Each join angle is obtained by performing an optimization calculation based on inverse kinematics using the candidates and the articulated structure.
    Type: Application
    Filed: August 29, 2019
    Publication date: April 7, 2022
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Yoshihiko NAKAMURA, Wataru TAKANO, Yosuke IKEGAMI, Takuya OHASHI, Kazuki YAMAMOTO, Kentaro TAKEMOTO
  • Publication number: 20220106412
    Abstract: A composite particle comprising: a core particle containing at least one type of polymer; and micronized cellulose that has an anionic functional group, is inseparably bonded to the core particle, and is disposed on a surface of the core particle, wherein an organic onium cation or an ammonium ion is bonded to at least a part of the micronized cellulose.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 7, 2022
    Applicants: TOPPAN INC., THE UNIVERSITY OF TOKYO
    Inventors: Nao NISHIJIMA, Shuji FUJISAWA
  • Patent number: 11291360
    Abstract: A visual field test assistance apparatus infers a current visual field status at each test point. A predetermined mixture distribution is applied to a prior-distribution, and parameters regarding the predetermined mixture distribution are learned with reference to time-series information of visual field test results obtained in the past regarding a plurality of cases. The visual field test assistance apparatus calculates an inference test result vector representing an inference result of visual sensitivity to be obtained by the visual field test at each test point, by Bayesian inference, and performs an information output process on the basis of the inference test result vector obtained by the inference.
    Type: Grant
    Filed: August 30, 2013
    Date of Patent: April 5, 2022
    Assignee: THE UNIVERSITY OF TOKYO
    Inventors: Ryo Asaoka, Hiroshi Murata
  • Publication number: 20220096568
    Abstract: It was found that bacteria belonging to the genus Clostridium induce accumulation of regulatory T cells (Treg cells) in the colon. Moreover, the present inventors found that regulatory T cells (Treg cells) induced by from these bacteria suppressed proliferation of effector T-cells. From these findings, the present inventors found that the use of bacteria belonging to the genus Clostridium or a physiologically active substance derived therefrom made it possible to induce proliferation or accumulation of regulatory T cells (Treg cells), and further to suppress immune functions.
    Type: Application
    Filed: July 9, 2021
    Publication date: March 31, 2022
    Applicant: The University of Tokyo
    Inventors: Kenya Honda, Koji Atarashi, Kikuji Itoh, Takeshi Tanoue