Patents Assigned to The University of Tokyo
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Publication number: 20240251242Abstract: A plurality of wireless devices arranged indoors, and transmitting wireless signals for acquiring position information, are authenticated. A terminal device acquires position information on the basis of the wireless signals received from the authenticated wireless devices. From the terminal device, information regarding the number of the authenticated wireless devices which are transmission sources of the wireless signals used as a bases for acquiring the position information, is acquired. On the basis of the acquired information regarding the number of the wireless devices, the position information acquired by the terminal device is authenticated.Type: ApplicationFiled: May 13, 2022Publication date: July 25, 2024Applicants: LOCATIONMIND INC., THE UNIVERSITY OF TOKYOInventors: Koichi CHINO, Naoki KIRITANI, Wataru OHIRA, Ranjit SAURAV, Manandhar DINESH, Ryosuke SHIBASAKI
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Patent number: 12045994Abstract: The invention relates to automatic discovery and evaluation of a motion by treating motion recognition as an optimization problem by considering a series of basic motions obtained by segmenting a subject motion. The method comprises segmenting time series data defining a motion of a subject into a plurality of segments, classifying each segment into a class for a basic motion by using time series data of the segment, and converting the motion of the subject to a sequence of high rank symbols in which each high rank symbol is formed from a series of the basic motions, wherein a function that calculates a score based on a set of a high rank symbol and a sequence of basic motions is provided and the motion of the subject is converted to the sequence of the high rank symbols by an optimization calculation using dynamic programming.Type: GrantFiled: August 28, 2019Date of Patent: July 23, 2024Assignee: THE UNIVERSITY OF TOKYOInventors: Yoshihiko Nakamura, Wataru Takano, Yosuke Ikegami
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Patent number: 12046390Abstract: A novel dopant according to the present disclosure includes an anion represented by the following Formula (1) and a counter cation. In Formula (1), R1 and R2 may be each at least one group selected from a nitro group, a cyano group, an acyl group, a carboxyl group, an alkoxycarbonyl group, a haloalkyl group, a sulfo group, an alkylsulfonyl group, an halosulfonyl group, and a haloalkylsulfonyl group, or may be a group formed by R1 and R2 bonded to each other [—SO2-L-SO2—] (where L represents a haloalkylene group). The counter cation may be a radical cation represented by Formula (2), where R1 and R2 represent electron-withdrawing groups that may be bonded to each other to form a heterocycle, and R3 to R5 represent a hydrogen atom, a hydrocarbon group that may have a substituent, or a heterocyclic group that may have a substituent. The dopant is capable of forming an electroconductive composition that shows a high conductivity.Type: GrantFiled: August 17, 2020Date of Patent: July 23, 2024Assignees: THE UNIVERSITY OF TOKYO, DAICEL CORPORATIONInventors: Toshihiro Okamoto, Tadanori Kurosawa, Junichi Takeya, Daiji Ikeda, Yasuyuki Akai
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Publication number: 20240241079Abstract: The present invention provides a transistor-based polyamine sensor with which it is possible to detect a polyamine easily and with high sensitivity. Specifically, the present invention provides a transistor-based polyamine sensor comprising a detection site, wherein an organic compound containing a carboxy group and a thiol group is immobilized on all or part of the surface of the detection site via the thiol group of the organic compound, a heavy metal ion is bound to the carboxy group of the organic compound, and a change in threshold voltage caused by bonding of the heavy metal ion to a polyamine is measured to detect the polyamine.Type: ApplicationFiled: December 20, 2021Publication date: July 18, 2024Applicants: The University of Tokyo, TOYOBO CO., LTD.Inventors: Tsuyoshi MINAMI, Koichiro ASANO, Hikaru TANAKA, Akari HIRATA, Kazutake HAGIYA
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Patent number: 12037906Abstract: A tunnel boring machine includes: a disc cutter including a cutter ring; and a member for use in measurement of a wear amount of the cutter ring with a three-dimensional shape measurement device, in which the member is provided at a part constant in relative position to the cutter ring.Type: GrantFiled: May 22, 2020Date of Patent: July 16, 2024Assignees: Komatsu Ltd., The University of TokyoInventors: Eiichi Morioka, Shinichi Terada, Rui Fukui, Yudai Yamada
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Patent number: 12037608Abstract: A gene-modified coxsackievirus that is to be used in oncolytic virotherapy and is improved in safety and/or aggressiveness is provided. A gene-modified coxsackievirus that contains a mutated genome with a coxsackievirus B3 wild-type (CVB3-WT) genome inserted with at least one polynucleotide constituted of a target sequence for at least one of either of miR-34a and miR-34c and is suppressed in proliferation in normal cells is provided.Type: GrantFiled: April 18, 2018Date of Patent: July 16, 2024Assignees: THE UNIVERSITY OF TOKYO, NPT CO., LTD.Inventors: Yang Jia, Shohei Miyamoto, Kenichiro Hara, Atsuhumi Iwanaga, Kenzaburo Tani
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Publication number: 20240228435Abstract: The present invention is a method for producing a tetrafluorosulfanyl group-containing aryl compound, in which a thioaryl compound represented by General Formula (2) is subjected to a reaction by adding to an olefin compound represented by General Formula (3) in the presence of a radical initiator to synthesize a tetrafluorosulfanyl group-containing aryl compound represented by General Formula (1) [in the formula, A1 is an aryl group which may have a substituent, or a heteroaryl group which may have a substituent; and R1, R2, R3, and R4 are each independently a hydrogen atom, a fluorine atom, or a chlorine atom, and two or more of R1, R2, R3, and R4 are a fluorine atom].Type: ApplicationFiled: March 15, 2024Publication date: July 11, 2024Applicants: AGC Inc., The University of TokyoInventors: Takashi OKAZOE, Kohsuke AIKAWA, Kyoko NOZAKI, Eisuke YASUO
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Patent number: 12029579Abstract: A medical apparatus for estimating a mental/neurological disease with high precision is provided. This medical apparatus includes a computational processing device, a recording device having an estimation program which causes the computational processing device to execute processing recorded therein, a calculation unit configured to calculate a score of a subject, a detection unit configured to detect a disease whose score exceeds a reference range, and an estimation unit configured to estimate a mental/neurological disease.Type: GrantFiled: July 11, 2019Date of Patent: July 9, 2024Assignees: PST INC., THE UNIVERSITY OF TOKYOInventors: Shinichi Tokuno, Shuji Shinohara, Mitsuteru Nakamura, Yasuhiro Omiya
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Patent number: 12033318Abstract: An estimation apparatus includes an input unit and an approximator. Input information including an image in which a bone appears is input into the input unit. The approximator is configured to determine an estimation result related to bone density of the bone from the input information. The approximator includes a learned parameter to obtain the estimation result.Type: GrantFiled: September 10, 2019Date of Patent: July 9, 2024Assignees: Kyocera Corporation, The University of TokyoInventors: Kenichi Watanabe, Masayuki Kyomoto, Shintaro Honda, Toru Moro, Sakae Tanaka
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Publication number: 20240218384Abstract: It is an object of the present invention to provide a method for editing or modifying plant genomes (a nuclear genome, a plastid genome, and a mitochondrial genome), and in particular, the editing or modification of a single nucleotide. Specifically, the present invention relates to a method for editing genomic DNAs in plant cells, namely, a nuclear genomic DNA, a plastid genomic DNA and a mitochondrial genomic DNA, wherein the method comprises converting target nucleotides on these genomic DNAs to other nucleotides. This conversion is carried out, for example, with cytidine deaminase, and in particular, with the aforementioned enzyme using a double-stranded DNA as a substrate.Type: ApplicationFiled: January 21, 2022Publication date: July 4, 2024Applicant: The University of TokyoInventors: Shin-ichi ARIMURA, Issei NAKAZATO, Nobuhiro TSUTSUMI, Ayako HOSODA
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Publication number: 20240220769Abstract: A machine learning processing circuit including a plurality of neuron cell circuit. Each of the plurality of neuron cell circuit includes an input unit that receives a plurality of input signals, an adder unit that adds the input signals received by the input unit, and a storage unit that holds output results of a non-linear function corresponding to input values, uses an output signal output by the adder unit, as an input value, and outputs an output result of the non-linear function corresponding to the input value.Type: ApplicationFiled: April 27, 2022Publication date: July 4, 2024Applicant: THE UNIVERSITY OF TOKYOInventors: Atsutake KOSUGE, Tadahiro KURODA
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Patent number: 12024717Abstract: According to the present invention, there are provided a method for producing a human T cell, which comprises the steps of inducing an iPS cell from a human T cell, and differentiating the iPS cell into a T cell; a pharmaceutical composition comprising the T cell produced by the method; and a method for cell-based immunotherapy using the method.Type: GrantFiled: August 12, 2020Date of Patent: July 2, 2024Assignee: The University of TokyoInventors: Hiromitsu Nakauchi, Shin Kaneko, Toshinobu Nishimura
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Publication number: 20240210248Abstract: A sensor element for detecting electromagnetic waves includes a substrate, an absorber configured to absorb the electromagnetic waves and generate heat, and at least one thermoelectric conversion element disposed between the substrate and the absorber to support a part of the absorber and configured to generate an electromotive force from the heat generated in the absorber by a transverse thermoelectric effect.Type: ApplicationFiled: April 12, 2022Publication date: June 27, 2024Applicant: The University of TokyoInventors: Satoru Nakatsuji, Ryota Uesugi, Tomoya Higo
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Publication number: 20240197964Abstract: Provided is a gel material for ophthalmic treatment useful as a synthetic vitreous body which is a novel intraocular tamponade material having a low swelling pressure, an appropriate elastic force, and no toxicity to ocular tissues, specifically, to retinas, and which is capable of stably maintaining a long-term stable tamponade effect. A gel material for ophthalmic treatment including a hydrogel in which a gel precursor cluster crosslinks to form a three-dimensional network. The gel precursor cluster has a structure with crosslinked monomer units or crosslinked polymer units present at concentrations less than a critical gelation concentration, and the gel precursor cluster has a relationship of G?<G? where G? represents a storage elastic modulus and G? represents a loss elastic modulus. The hydrogel has a polymer content of 50 g/L or less, a storage elastic modulus G? of 1 to 10,000 Pa at a frequency of 1 Hz, and a fractal dimension of 1.5 to 2.5.Type: ApplicationFiled: March 5, 2024Publication date: June 20, 2024Applicants: THE UNIVERSITY OF TOKYO, UNIVERSITY OF TSUKUBAInventors: Takamasa SAKAI, Yuichi TEI, Fumiki OKAMOTO, Sujin HOSHI
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Publication number: 20240201189Abstract: [Problem] To provide a fluorescent probe capable of detecting pancreatic cancer specifically. [Solution] A fluorescent probe for use in the detection of pancreatic cancer, which comprises a compound represented by general formula (I) or a salt thereof.Type: ApplicationFiled: April 12, 2022Publication date: June 20, 2024Applicant: The University of TokyoInventors: Yasuteru URANO, Mako KAMIYA, Kiyoshi HASEGAWA, Takeaki ISHIZAWA, Ryugen TAKAHASHI
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Publication number: 20240200037Abstract: It is an object of the present invention to provide a method for producing a virus to obtain high-purity virus particles, said method being more efficient than conventional methods.Type: ApplicationFiled: April 14, 2022Publication date: June 20, 2024Applicant: The University of TokyoInventors: Takashi OKADA, Mikako WADA
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Publication number: 20240199656Abstract: [Problem] To provide a novel compound promising as a probe for a boron neutron capture therapy (BNCT). [Solution] A compound represented by general formula (I) below or a salt thereof.Type: ApplicationFiled: February 21, 2022Publication date: June 20, 2024Applicant: The University of TokyoInventors: Yasuteru URANO, Mako KAMIYA, Junya TSUNETOMI
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Publication number: 20240197726Abstract: [Problem] To provide: a novel tetrahydroisoquinoline (THIQ) alkaloid compound having a macrocyclic structure; an intermediate of the compound; and a method for producing the compound. [Solution] Provided is a compound represented by formula (I), or a pharmaceutically acceptable salt thereof. The present invention also provides: a method for synthesizing this compound; and an intermediate compound useful in this synthesis.Type: ApplicationFiled: March 1, 2022Publication date: June 20, 2024Applicant: THE UNIVERSITY OF TOKYOInventors: Hiroki OGURI, Ryo TANIFUJI
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Publication number: 20240194235Abstract: A magnetic memory element includes an antiferromagnetic layer made of a canted antiferromagnet having a magnetic order with a canted magnetic moment, and a contact layer in contact with the antiferromagnetic layer and made of a different material from the canted antiferromagnet. A roughness of an interface between the antiferromagnetic layer and the contact layer is 1.0 nm or less. A spin current flowing through the contact layer is configured to induce a torque to act on the magnetic order of the antiferromagnetic layer, thereby allowing reversal of the magnetic order.Type: ApplicationFiled: April 12, 2022Publication date: June 13, 2024Applicant: The University of TokyoInventors: Satoru Nakatsuji, Tomoya Higo
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Publication number: 20240190994Abstract: It is an object of the present invention to provide a fusion protein of a molecule that recognizes cancer cells or the like and a mutant streptavidin, wherein the fusion protein is for use in the treatment or diagnosis of a cancer. According to the present invention, provided is a fusion protein, wherein an antigen-binding molecule having a molecular weight of 20,000 or less is bound, via a linker sequence, to the N-terminal side and/or C-terminal side of the amino acid sequence as set forth in SEQ ID NO: 1, provided that the C-terminal amino acid sequence consisting of Pro-Ser-Ala-Ala-Ser His-His-His-His-His-His may be partially or entirely deleted.Type: ApplicationFiled: March 24, 2022Publication date: June 13, 2024Applicants: The University of Tokyo, SAVID THERAPEUTICS INC.Inventors: Toshiya TANAKA, Tatsuhiko KODAMA, Motomu KANAI, Kenzo YAMATSUGU, Toshifumi TATSUMI, Kazuki TAKAHASHI, Akira SUGIYAMA, Masanobu TSUKAGOSHI