Patents Assigned to The University of Tokyo
  • Pseudo 3-D space representation system, pseudo 3-D space constructing system, game system and electronic map providing system
    Patent number: 6972757
    Abstract: Disclosed is a pseudo 3-D space representation system capable of creating a cubic pseudo 3-D space with a plurality of 2-D images by simple operation. An operation display means displays plural images to a user who is requested to specify a same area on each of two or more images by using an area specifying means. A specified area associating means associates the specified area on one image with the specified area on the other image as one set or plural sets of common parts. An image transforming means transforms one or both images by matching the specified areas by affine transformation and an image display means displays both images as superposed on one the other.
    Type: Grant
    Filed: January 3, 2002
    Date of Patent: December 6, 2005
    Assignee: President of the University of Tokyo
    Inventors: Masatoshi Arikawa, Hiroya Tanaka, Ryosuke Shibasaki
  • Genes and polypeptides relating to prostate cancers
    Publication number: 20050259483
    Abstract: Objective methods for detecting and diagnosing prostate cancer (PRC) or prostatic intraepithelial neoplasia (PIN) are described herein. In one embodiment, the diagnostic method involves the determining an expression level of PRC-associated gene that discriminate between PRC or PIN and nomal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of either or both of PRC and PIN, methods of treating either or both of PRC and PIN and method of vaccinating a subject against either or both of PRC and PIN.
    Type: Application
    Filed: March 23, 2005
    Publication date: November 24, 2005
    Applicants: Oncotherapy Science, Inc., The University of Tokyo
    Inventors: Yusuke Nakamura, Toyomasa Katagiri, Hidewaki Nakagawa, Shuichi Nakatsuru
  • Molecular entity for controlling a calcium
    Publication number: 20050260657
    Abstract: A molecular entity for controlling a calcium according to a first aspect of the invention is (a) an amino acid sequence shown in an amino acid sequence number 1-406 of SEQ ID NO: 1 or (b) an amino acid sequence wherein a part of the amino acid sequence of the amino acid sequence number 1-406 of SEQ ID NO: 1 is deleted, substituted or added.
    Type: Application
    Filed: April 19, 2005
    Publication date: November 24, 2005
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Katsuhiko Mikoshiba, Mitsuhiro Hattori, Takayasu Higo
  • Method for diagnosing pancreatic cancer
    Publication number: 20050260639
    Abstract: Objective methods for detecting and diagnosing pancreatic cancer (PNC) are described herein. In one embodiment, the diagnostic method involves determining the expression level of PNC-associated gene that discriminates between PNC cells and normal cells. The present invention further provides methods of screening for therapeutic agents useful in the treatment of pancreatic cancer, methods of treating pancreatic cancer and method of vaccinating a subject against pancreatic cancer.
    Type: Application
    Filed: March 24, 2005
    Publication date: November 24, 2005
    Applicants: Oncotherapy Science, Inc., The University of Tokyo
    Inventors: Yusuke Nakamura, Toyomasa Katagiri, Hidewaki Nakagawa
  • Methods for damaging cells using effector functions of anti FAM3D antibodies
    Publication number: 20050214303
    Abstract: The present invention relates to the use of cytoxicity based on the effector function of anti-FAM3D antibodies. Specifically, the present invention provides methods and pharmaceutical compositions that comprise an anti-FAM3D antibody as an active ingredient for damaging FAM3D-expressing cells using antibody effector function. Since FAM3D is strongly expressed in lung cancer cells, the present invention is useful in lung cancer therapies.
    Type: Application
    Filed: March 24, 2004
    Publication date: September 29, 2005
    Applicants: Oncotherapy Science, Inc., Japan as Represented by the President of the University of Tokyo
    Inventors: Yusuke Nakamura, Yataro Daigo
  • Method of diagnosing ovarian endometriosis
    Publication number: 20050214836
    Abstract: Disclosed are methods of diagnosing ovarian endometriosis using differentially expressed genes. Ovarian endometriosis associated genes identified herein or their gene products are useful as a diagnostic markers for identifying or detecting ovarian endometriosis. Also disclosed are methods of screening compounds serving as agents for treating ovarian endometriosis, and methods of treating ovarian endometriosis and method or vaccinating a subject against ovarian endometriosis.
    Type: Application
    Filed: February 28, 2005
    Publication date: September 29, 2005
    Applicants: Oncotherapy Science, Inc., The University of Tokyo
    Inventors: Yusuke Nakamura, Toyomasa Katagiri
  • Backlash clutch and joint mechanism for a robot comprising the clutch
    Patent number: 6948400
    Abstract: A backlash comprises a first rotation member and a second rotation member, each of which is provided rotatably-about the same axis, and which are engageable together in a rotating direction of the members by driving contact between respective radial extension surfaces thereof,and where a backlash gap is provided between the respective radial extension surfaces of the first and the second rotation members to permit fee rotation between the first and second rotation members in a range of the backlash gap in the rotating direction of the members.
    Type: Grant
    Filed: February 7, 2003
    Date of Patent: September 27, 2005
    Assignee: The University of Tokyo
    Inventors: Yoshihiko Nakamura, Masafumi Okada, Tatsuya Goto
  • Device and method for manufacturing carbon nanotube
    Publication number: 20050207965
    Abstract: There is provided a device for manufacturing carbon nanotube. The devices has a chamber support part for supporting a chamber which contains a plurality of microstructures, each of which is separated from each other by an interval; a gas providing part, connected to the chamber, for flowing at least one reactant gas, including raw material gas for manufacturing carbon nanotubes, through the chamber; a measurement part for measuring a change in physical properties of at least one of the plurality of microstructures by using detecting part; and a control part for controlling the gas providing part based on the measured change in physical properties.
    Type: Application
    Filed: January 19, 2005
    Publication date: September 22, 2005
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Isao Shimoyama, Shigeo Maruyama, Kiyoshi Matsumoto, Kazunori Hoshino, Yoichi Murakami
  • Method for fabricating a high density integrated light-emitting device, and high density integrated light-emitting device
    Publication number: 20050200272
    Abstract: A plurality of electrode pairs are prepared. The electrode pieces of each electrode pair are opposite to one another. Then, voltages are applied to the electrode pairs so as to accumulate illuminants in between the electrode pieces of the electrode pairs by using the electric fields generated between the electrode pieces from the voltages.
    Type: Application
    Filed: January 19, 2005
    Publication date: September 15, 2005
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Isao Shimoyama, Kiyoshi Matsumoto, Kazunori Hoshino, Koichi Yamada
  • Color developing structure and display device
    Publication number: 20050179836
    Abstract: A color developing structure includes a substrate, at least one color developing object provided on the substrate, and control means for controlling the color development of the color developing object by a mechanical, electric or chemical action. The color developing object has a wavelength-selective reflection or transmission characteristic.
    Type: Application
    Filed: January 19, 2005
    Publication date: August 18, 2005
    Applicant: The University of Tokyo
    Inventors: Isao Shimoyama, Kiyoshi Matsumoto, Eiji Iwase
  • Fine carbon wires and methods for producing the same
    Patent number: 6890505
    Abstract: A novel fine carbon wire includes a needle-like fullerene crystal having a smooth surface. The fine carbon wire can be produced by a method including the steps of (1) adding a solution containing the fullerene dissolved in a first solvent to a second solvent having less solvency for the fullerene than the first solvent; (2) forming a liquid-liquid interface between the solution and the second solvent; and (3) depositing a fine carbon wire at the liquid-liquid interface.
    Type: Grant
    Filed: April 17, 2002
    Date of Patent: May 10, 2005
    Assignee: The University of Tokyo
    Inventors: Kun-ichi Miyazawa, Makoto Kuwabara
  • Methods of controlling proliferation of cancer cells and cell death
    Publication number: 20050070015
    Abstract: This invention demonstrates that the PEG10 protein suppresses apoptosis and promotes cancer cell growth. Furthermore, PEG10 protein was found to be degraded through interaction with SIAH1 protein. This invention provides methods of regulating cell growth and cell death using the PEG10 protein. Furthermore, the present invention provides methods of screening for novel anticancer agents which use the PEG10 protein. The screening of this invention enables development of pharmaceutical agents that induce apoptosis and suppress cell growth by specifically targeting cancer cells. In particular, since the PEG10 protein is specifically expressed in hepatoma cells, it is an ideal target molecule for diagnosis and treatment of hepatoma.
    Type: Application
    Filed: August 21, 2002
    Publication date: March 31, 2005
    Applicants: JAPAN AS REPRESENTED BY THE PRESIDENT OF THE UNIVERSITY OF TOKYO, ONCOTHERAPY SCIENCE, INC.
    Inventors: Yusuke Nakamura, Yoichi Furukawa
  • Genes and polypeptides relating to human colon cancers
    Publication number: 20050069930
    Abstract: The present application provides novel human genes RNF43 whose expression is markedly elevated in colorectal cancers, as well as CXADRL1 and GCUD1 whose expression is markedly elevated in gastric cancers compared to corresponding non-cancerous tissues. The genes and polypeptides encoded by the genes can be used, for example, in the diagnosis of a cell proliferative disease, and as target molecules for developing drugs against the disease.
    Type: Application
    Filed: August 10, 2004
    Publication date: March 31, 2005
    Applicants: Oncotherapy Science, Inc., The University of Tokyo
    Inventors: Yusuke Nakamura, Yoichi Furukawa, Hideaki Tahara, Takuya Tsunoda
  • Method for measuring the concentration of a substance in a living body and device for measuring the same concentration
    Publication number: 20050013779
    Abstract: A fluorescence indicator is injected into a living body from a container via an injecting inlet to be chemically reacted with a substance in the living body. Then, an excitation light is irradiated to the living body from an excitation light source. Then, the thus obtained reflected light is reflected multiply at an reflective film formed on the inner wall of the container, and introduced into a detecting section, where a fluorescence response originated from the chemical bond between the substance and the fluorescence indicator and contained in the reflected light is detected.
    Type: Application
    Filed: June 3, 2004
    Publication date: January 20, 2005
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Isao Shimoyama, Kiyoshi Matsumoto, Sumito Nagasawa
  • Method of simulating fluctuation of oil, program of the same and system of the same
    Publication number: 20050010384
    Abstract: A fluctuation of oil in a region is simulated, the region being composed of at least one selected from at least one kinds of liquid inert to the oil and at least one kinds of solid inert to the oil. The region is divided into a plurality of polygonal sections each having the same size and the same shape. A distribution of the oil in each of the polygonal sections is defined as a polygonal oil section. A fluctuation in each of the polygonal oil sections is calculated. The distribution of the oil in each of the polygonal sections is redefined as a polygonal oil section in accordance with the fluctuation of the oil in each of the polygonal oil sections. A certain times of the calculating and the redefining are repeated at a certain regular intervals.
    Type: Application
    Filed: May 10, 2004
    Publication date: January 13, 2005
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Chang Rheem, Hajime Yamaguchi
  • Complex and method for producing epoxides by using the complex
    Patent number: 6833442
    Abstract: There is provided a complex having a specified chemical structure and an asymmetric catalyst using such a complex. Further, an epoxidation of amine or ketone is enantioselectively conducted by using such an asymmetric catalyst.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: December 21, 2004
    Assignee: The University of Tokyo
    Inventors: Masakatsu Shibasaki, Takashi Ohshima, Tetsuhiro Nemoto
  • Apparatus and method for generating image
    Publication number: 20040223055
    Abstract: An apparatus for generating an image includes a vehicle moving at a predetermined direction; and a plurality of cameras arranged on the vehicle along a linear line parallel to the predetermined direction and at different angles from each other with respect to the predetermined direction so as to include all areas of images to be acquired. The apparatus forms one image by integrating images at the same point acquired by the cameras, respectively without being synchronized the cameras with each other and using any external sensor.
    Type: Application
    Filed: February 17, 2004
    Publication date: November 11, 2004
    Applicant: The University of Tokyo
    Inventors: Katsushi Ikeuchi, Masao Sakauchi, Hiroshi Kawasaki
  • Image displaying method and an image display
    Patent number: 6806851
    Abstract: An image display has a substrate, plural optical sources on the substrate, and a microlens-array in which plural microlens are arranged so as to be opposed to the respective optical sources. Then, driving devices are provided under the optical sources. The driving devices move the microlenses relatively for the respective optical sources. At the same time, the optical intensities or the optical wavelengths of light beams from the optical sources are varied with synchronized with the above relative movements, and taken out as image information of an object to be observed. As a result, a three-dimensional image of the object can be provided.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: October 19, 2004
    Assignee: The University of Tokyo
    Inventors: Isao Shimoyama, Kazunori Hoshino
  • Method of forming an artificial Shiro of Matsutake
    Patent number: 6803226
    Abstract: A method of forming an artificial Shiro of Matsutake comprises culturing Matsutake hyphae in a culture substrate containing a substance capable of controlling the cell membrane permeability of the hyphae as an active principle, and a method of forming an artificial Shiro of Matsutake comprises culturing Matsutake hyphae in a culture substrate containing a substance capable of enhancing the hydrophilic property of the hyphae as an active principle.
    Type: Grant
    Filed: January 24, 2002
    Date of Patent: October 12, 2004
    Assignee: The University of Tokyo
    Inventors: Kazuo Suzuki, Alexis Guerin-Laguette, Lu-Min Vaario
  • Input distribution type packet switch network and an input distribution type packet switch
    Patent number: 6804231
    Abstract: An input distribution packet switch network includes a plurality of 2×2 switch elements and packet input modules for the switch network. The switch elements are arranged in multistage and connected in accordance with Shuffle type topology to constitute a N×N switch network (N=2k, k: integer number of 2 and over). The links of the leftmost and rightmost switch elements are connected to one another so that the N×N switch network can have a ring architecture. The packet input modules are distributed laterally in the switch network.
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: October 12, 2004
    Assignee: The University of Tokyo
    Inventors: Tadao Saito, Hitoshi Aida, Hiroaki Morino, Thai Thach Bao