Abstract: Methods and kits for treatment of glaucoma are disclosed. In general, the methods of the invention include administering a therapeutically effective amount of a deprenyl compound to a subject such that the subject is treated for glaucoma.

Abstract: Hydrogen Sulfide is substantially completely removed from a gas stream in a two-stage operation. Hydrogen Sulfide is first partially oxidized to sulfur dioxide and the sulfur dioxide reacted with part of the remaining hydrogen sulfide while the hydrogen sulfide not so reacted is subsequently oxidized, thereby removing all of the hydrogen sulfide from the gas stream.

Abstract: Insoluble particulate materials, which may be in solid or liquid form, are dispersed in a continuous non-aqueous phase and the dispersion rendered stable and resistant to phase separation by an in-situ stabilization procedure involving the formation of chemical bonds among the stabilizer components and to dispersed phases to form a network surrounding the particles which is compatible with the continuous phase. The invention has particular application for the formation of stabilized polyolefin-modified bitumen compositions for paving and other applications.

Abstract: The parameters of a gas-liquid contact apparatus for the removal of a component of a gas stream in which an impeller-apertured shroud combination is immersed in a liquid phase to which the gas stream is fed at a gas flow rate of Q. The structural and operating parameters of the apparatus are quantified to provide a Shear Effectiveness Index (SEI) value of from about 1 to about 10 and an Effective Shear Index (ESI) value of from about 1 to about 2500.

Abstract: Components, usually but not exclusively gaseous components, are removed in a liquid medium from gas streams and chemically converted into an insoluble phase or physically removed. Specifically, hydrogen sulfide may be removed from gas streams by oxidation in aqueous chelated transition metal solution in a modified agitated flotation cell. The same principal may be employed in other procedures in which a gaseous phase is dispersed in a liquid phase to effect an interaction between components present in such phases. A gas-liquid contact apparatus, generally a combined chemical reactor and solid product separation device, comprising such modified agitated flotation cell is also described. In order to effect mass transfer and rapid reaction gas bubbles containing hydrogen sulfide and oxygen are formed by rotating an impeller at a blade tip velocity of at least about 350 in/sec. to achieve the required shear.

Abstract: Components, usually but not exclusively gaseous components, are removed in a liquid medium from gas streams and chemically converted into an insoluble phase or physically removed. Specifically, hydrogen sulfide may be removed from gas streams by oxidation in aqueous chelated transition metal solution in a modified agitated flotation cell. The same principal may be employed in other procedures in which a gaseous phase is dispersed in a liquid phase to effect an interaction between components present in such phases. A gas-liquid contact apparatus, generally a combined chemical reactor and solid product separation device, comprising such modified agitated flotation cell is also described. In order to effect mass transfer and rapid reaction gas bubbles containing hydrogen sulfide and oxygen are formed by rotating an impeller at a blade tip velocity of at least about 350 in/sec. to achieve the required shear.

Abstract: Components, usually but not exclusively gaseous components, are removed in a liquid medium from gas streams and chemically converted into an insoluble phase or physically removed. Specifically, hydrogen sulfide may be removed from gas streams by oxidation in aqueous chelated transition metal solution in a modified agitated flotation cell. The same principal may be employed in other procedures in which a gaseous phase is dispersed in a liquid phase to effect an interaction between components present in such phases. A gas-liquid contact apparatus, generally a combined chemical reactor and solid product separation device, comprising such modified agitated flotation cell is also described. In order to effect mass transfer and rapid reaction gas bubbles containing hydrogen sulfide and oxygen are formed by rotating an impeller at a blade tip velocity of at least about 350 in/sec. to achieve the required shear.

Abstract: A method for isolating a cDNA specific for the human ryanodine receptor is disclosed. The gene is associated with malignant hyperthermia, a hypermetabolic syndrome triggered primarily by inhalation anesthetics. The cDNA can be cloned and expressed in a recombinant plasmid or phage. The cDNA, or fragments thereof, is used as diagnostic probes for individuals at risk for malignant hyperthermia using restriction fragment length polymorphism analysis. The cDNA is that sequenced in FIG. 2 of this specification.

Abstract: Hydrogen sulfide or other gaseous component is removed from a gas stream containing the same by distribution of the gas stream in the form of fine bubbles by a rotary impeller and stationary shroud arrangement at a submerged location in an aqueous iron or other transition metal chelate solution, or other suitable catalyst, contained in an enclosed reaction vessel. Sulfur particles, or other insoluble phase product, of narrow particle size range formed in the reaction are floated off from the iron chelate solution. An oxygen-containing gas stream also is distributed in the form of fine bubbles by a separate rotary impeller and stationary shroud arrangement at a separate submerged location in the iron chelate solution. The second submerged location generally is separated from the first by a baffle extending downwardly in the reaction vessel from a top closure towards a bottom closure.

Abstract: Components, usually but not exclusively gaseous components, are removed in a liquid medium from gas streams and chemically converted into an insoluble phase or physically removed. Specifically, hydrogen sulfide may be removed from gas streams by oxidation in aqueous chelated transition metal solution in a modified agitated flotation cell. A gas-liquid contact apparatus, generally a combined chemical reactor and solid product separation device, comprising such modified agitated flotation cell also is described. In order to effect efficient mass transfer and rapid reaction, gas bubbles containing hydrogen sulfide and oxygen are formed by rotating an impeller at a blade tip velocity of at least about 350 in/sec. to achieve the required shear. To assist in the reaction, a surrounding shroud has a plurality of openings, generally of aspect ratio of approximately 1, of equal diameter and arranged in uniform pattern, such as to provide a gas flow therethrough less than about 0.02 lb/min/opening in the shroud.

Abstract: A purified DNA molecule comprises a DNA sequence of approximately 15.1 kb coding for normal or mutant RYR1 protein having a molecular weight of approximately 564,740 daltons. The DNA molecule has an endonuclease restriction map of FIG. 1 and a sequence of FIG. 2.

Abstract: There is disclosed an implant for anchoring in bone and/or fibrous connective tissue and to which a prosthesis such as a dental bridge may be connected through connecting components. The implant is of tapered design defining a wide top portion for connection to the connecting components and a tapered body comprising upper and lower regions. The lower bone-engaging region of the implant is provided with a porous surface into which bone may grow thereby anchoring the implant. The upper region of the implant has a surface suitable for bone attachment which is different from the surface of the lower region. In one embodiment, the upper portion has a larger taper angle than the rest of the implant for increased stability and stress transfer to the surrounding bone. In another embodiment, the surface of the upper region is coated with a bioreactive coating to allow direct bonding of bone and/or soft connective tissue (gingival tissue) thereby inhibiting epithelial migration apically.

Abstract: A modified hemoglobin comprising hemoglobin which is cross-linked with a cross-linking reagent. The cross-linking reagent is selected such that the .beta.-chains are cross-linked within the 2,3-diphosphoglycerate binding site and the linkage distance between the .beta.-chains is between about 5 to 9 angstroms. A method of preparing the modified hemoglobin and its use as a blood substitute or a plasma expander are also described.

Abstract: A device for timing and metering gaseous fuels into an internal combustion engine has a cylindrical solenoid cavity with a portion projecting away from the cavity containing a bore coaxial with the cylindrical cavity. The portion also has gas passageways. An injector tip is secured to the portion so that it can be adjusted in position toward and away from the cavity. The injector tip has an orifice, and a valve head on a pintle moving in the bore is adapted to open and close the orifice. The other end of the pintle is secured to the armature of a multipole solenoid which includes a plurality of plate-like, spaced ribs covering a substantially circular configuration and located within the cavity. The length of the pintle is such that, when the head is seated against the valve seat to close the orifice, the armature is spaced from the ribs, and when the armature is seated against the ribs, the head is off the valve seat, thus opening the orifice.

Abstract: A local area network is provided with increased tolerance to faults by arranging multiple hubs in nodes in the network. Internal connections in each hubs of the same node upon detection of a failure to provide an alternate path for data transmission in the network.

Abstract: Mammalian synovial phospholipase A.sub.2 (sPLA.sub.2) enzymes are provided, as well as DNA constructs encoding these enzymes, methods of producing the enzymes recombinantly, and antibodies thereto. Therapeutic methods employing anti-synovial phospholipase antibodies are also provided, in addition to diagnositc methods and other applications of sPLA.sub.2.

Abstract: A probe for ultrasound testing or treatment of a molten metal is provided. The probe includes an ultrasound transmitting rod having a downstream end adapted to contact molten metal under test or treatment. A piezoelectric crystal is provided on the probe and is adapted to supply ultrasound to or receive ultrasound from the rod. A rod cooling station is located near the downstream end of the rod and is operable to create in the rod, a steep temperature gradient at least equivalent to 700.degree. C. over a length of 50 mm from the point of melt contact for a cylindrical steel rod 25 mm in diameter when the probe is in contact with the molten metal at melt temperature. A method of testing a liquid molten melt is also provided.

Abstract: Bitumen-polyolefin compositions, e.g. for use as binders in paving compositions, are stabilized by an emulsifier system comprising a polyethylene wax terminally functionalized with acidic groups and having a polymeric main chain structure which is compatible with the polyolefin of the dispersed phase of the binder. In a preferred embodiment, the emulsifier system also includes an inorganic metal compound which will react chemically with the terminal functional groups of the polyethylene wax. Especially preferred is maleated polyethylene wax (as the polyethylene wax) and ferric oxide (as the inorganic metal compound). The emulsifier system forms a sheath of inorganic material around the dispersed polyolefin droplets, to stabilize them and to hinder their floatation to the surface of the binder composition.

Abstract: A process for treating metal comprises applying a positive DC potential to an ionic melt layer disposed on the surface of a liquid metal. The application of this potential provides a plasma phase above the ionic melt layer and induces a flow of electrons from the liquid metal towards the plasma phase. The ionic melt layer is capable of being maintained in a liquid state when it is in contact with the liquid metal. The process can be used either to remove impurities from the liquid metal, to alloy the liquid metal by adding metal compounds in the ionic melt layer, to recover metals from waste, or to perform a combination of these functions. An apparatus for treating liquid metals is also provided.

Abstract: A process of treating meal containing vegetable proteins is disclosed. This process includes the step of extracting the metal with a suitable aqueous solvent in which the vegetable proteins are soluble to obtain an extraction solution. The solubility of the dissolved protein in the extraction solution is then adjusted to precipitate at least some of the protein and therefore obtain a precipitated protein fraction and an unprecipitated protein fraction in solution. The precipitated protein fraction is then separated from the protein fraction in solution, and the unprecipitated protein fraction is separated from the undesirable components in the solution by membrane processing. Each of the protein fractions is then suitably dried to recover the proteins.