Abstract: There is described a structural material comprising a substrate and a binder characterised in that the binder comprises a bio-silicate and a process for the manufacture thereof.

Abstract: The invention relates to the induction of apoptosis by inhibition of the sirtuin SIRT1 expression, in particular the induction of apoptosis in tumour cells. Materials and methods for inhibiting SIRT1 expression are provided, including RNA interference methods. In particular, the invention provides a method of treating a proliferative disease comprising administering to an individual in need thereof an effective amount of a SIRT1 inhibitor.

Abstract: There is described novel organo-platinum luminophores comprising a complex of formula (I). The luminophores have application as the emissive component in organic light emitting diodes.

Abstract: A method and apparatus for producing an estimate of the acoustic response an environment. The method comprises receiving a first signal, and a second signal including a part of the first signal. The first and second signals are combined to produce a third signal. The first signal is combined with itself to produce a fourth signal. A plurality of weighted means of said third signal are computed and summed to produce a plurality of first summations. A plurality of weighted means of said fourth signal are computed and summed to produce a plurality of second summations. Said estimate is generated from said first and second summations.

Abstract: We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.

Abstract: Monoterpenoid esters that have been modified to include a sugar pendant group are disclosed. Plant glycosyltransferase enzymes are provided that function to add a sugar, typically glucose, to monoterpenoids in a bioreactor for the production of glycosylated monoterpenoid esters, together with nucleic acid molecules encoding such enzymes and vectors and transgenic cells including such nucleic acid molecules.

Abstract: Provided is a Schottky emitter having the conical end with a radius of curvature of 2.0 ?m on the emission side of an electron beam. Since a radius of curvature is 1 ?m or more, a focal length of an electron gun can be longer than in a conventional practice wherein a radius of curvature is in the range of from 0.5 ?m to not more than 0.6 ?m. The focal length was found to be roughly proportional to the radius of the curvature. Since the angular current intensity (the beam current per unit solid angle) is proportional to square of the electron gun focal length, the former can be improved by an order of magnitude within a practicable increase in the emitter radius. A higher angular current intensity means a larger beam current available from the electron gun and the invention enables the Schottky emitters to be used in applications which require relatively high beam current of microampere regime such as microfocus X-ray tube, electron probe micro-analyzer, and electron beam lithography system.

Abstract: We describe glycosyltransferase polypeptides that modify sesquiterpenoids and including pharmaceutical compositions comprising glycosylated sesquiterpenoids; methods to treat diseases, in particular cancer, bacterial and fungal infections and also flavourings and scents comprising glycosylated sesquiterpenoids.

Abstract: We describe the production of nucleotide sugars other than uridine diphosphate glucose (UDP-glucose), for example UDP-rhamnose, and the use of these nucleotide sugars in the modification of acceptor molecules.

Abstract: This invention relates to nucleic acid molecules which comprise nucleic acid sequences which encode enzymes involved in the biosynthesis of n-3 fatty acids, particularly docosahexanoic acid (DHA), or variants thereof; polypeptides encoded by said nucleic acids; cells transfected with said nucleic acid sequences and products comprising said nucleic acid sequences, polypeptides and/or cells.

Abstract: A camera A produces a 3D natural image B which is re-oriented and repositioned at N to predetermined parameters. Different processes C, D, E extract different features from the image to provide different processed images. The data space occupied by the processed images is reduced, for example by Principle Component Analysis, at F, G, H and the reduced processed images are combined at O to provide an image key I representative of the image B. The image key I is compared at J with stored image keys L of known images, and the output comparison is sorted at K to produce a final list M of potential matches. In a verification process, just a single image key L may be compared. The processed images at C, D, E may alternatively be combined prior to a single subspace reduction and/or optimisation method. 2D data may be combined with or used instead of the 3D data.

Abstract: We describe glycosyltransferase nucleic acids and proteins isolatable from Arabidopsis thaliana, transgenic cells expressing said glycosyltransferases, and bioreactors comprising said transgenic cells together with nutrient medium for supporting the growth of said cell that includes at least one exogenous substrate which is a substrate for said glycosyltransferase, and wherein said nutrient medium does not include an exogenous supply of UDP-glucose.

Abstract: We describe a microbial cell, typically a bacterial cell, genetically engineered to produce a modified sugar nucleotide, for example UDP glucuronic acid, and the use of the modified sugar to transfer glucuronic acid to small acceptor molecules.

Abstract: We describe a screening method for the identification of glycosyltransferase polypeptides that regioselectively modify aglycones and the use of said glycosyltransferase polypeptides to modify aglycones.

Abstract: We describe fusion proteins comprising a bacterial immunity polypeptide and their use in affinity purification of protein complexes.

Abstract: We describe a transgenic plant with altered expression of a gene that encodes a sequence variant of a transcription factor and which has altered seed dormancy.

Abstract: We describe a plant lipase polypeptide and nucleic acids that encode said polypeptide which has homology to a patatin and which has phospholipase and/or triacylglycerol lipase activity.

Abstract: The present invention relates to synthetic receptors, products and methods which are useful in relation to the binding of phosphates for example in water purification and renal dialysis systems.

Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glycosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.

Abstract: The invention relates to transgenic cells which have been transformed with nucleic acids encoding glucosyltransferase polypeptides (GTases) and vectors for use in transformation of said cells.