Abstract: The present disclosure relates general to devices, systems, and methods of using such devices in creating and handling hanging drops of fluid. The present disclosure also relates to cell culture devices, methods and/or systems of using such devices as well as the use of cell culture devices, for example, for research and high throughput screening.
Type:
Grant
Filed:
January 28, 2011
Date of Patent:
December 9, 2014
Assignees:
The Regents of The University of Michigan, 3D Biomatrix, Inc.
Inventors:
Shuichi Takayama, Yi-Chung Tung, Amy Yu-Ching Hsiao, Edward Jan
Abstract: The present application describes a crossbar memory array. The memory array includes a first array of parallel nanowires of a first material and a second array of parallel nanowires of a second material. The first and the second array are oriented at an angle with each other. The array further includes a plurality of nanostructures of non-crystalline silicon disposed between a nanowire of the first material and a nanowire of the second material at each intersection of the two arrays. The nanostructures form a resistive memory cell together with the nanowires of the first and second materials.
Type:
Grant
Filed:
November 7, 2011
Date of Patent:
December 9, 2014
Assignee:
The Regents of The University of Michigan
Abstract: Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
Type:
Grant
Filed:
May 11, 2010
Date of Patent:
December 9, 2014
Assignee:
The University of Tennessee Research Foundation
Inventors:
Charles Ryan Yates, Duane Douglas Miller, Mostafa Waleed Gaber, Karin Emmons Thompson, Kui Zeng, Jordan J. Toutounchian
Abstract: A vehicle has a trailer backup steering input apparatus, a trailer backup assist control module coupled to the a trailer backup steering input apparatus, and an electric power assist steering system coupled to the trailer backup assist control module and. The trailer backup steering input apparatus is configured for outputting a trailer path curvature signal approximating a desired curvature for a path of travel of a trailer towably coupled to the vehicle. The trailer backup assist control module is configured for determining vehicle steering information as a function of the trailer path curvature signa. The electric power assist steering system is configured for controlling steering of steered wheels of the vehicle as a function of the vehicle steering information.
Type:
Grant
Filed:
December 23, 2011
Date of Patent:
December 9, 2014
Assignees:
Ford Global Technologies, The Regents of The University of Michigan
Inventors:
Douglas Scott Rhode, David Dean Smit, Erick Michael Lavoie, Martin Fitzpatrick Frey, Thomas Edward Pilutti, Taehyun Shim, Matt Y. Rupp, Roger Arnold Trombley
Abstract: A method for creating a nanostructure according to one embodiment includes depositing material in a template for forming an array of nanocables; removing only a portion of the template such that the template forms an insulating layer between the nanocables; and forming at least one layer over the nanocables. A nanostructure according to one embodiment includes a nanocable having a roughened outer surface and a solid core. A nanostructure according to one embodiment includes an array of nanocables each having a roughened outer surface and a solid core, the roughened outer surface including reflective cavities; and at least one layer formed over the roughened outer surfaces of the nanocables, the at least one layer creating a photovoltaically active p-n junction. Additional systems and methods are also presented.
Type:
Grant
Filed:
October 25, 2010
Date of Patent:
December 9, 2014
Assignees:
Q1 Nanosystems, Inc., The Regents Of The University Of California
Inventors:
Ruxandra Vidu, Brian Argo, John Argo, Pieter Stroeve, Saif Islam, Jie-Ren Ku, Michael Chen
Abstract: Disclosed is an artificial bone material having controlled calcium ion elution, which does not induce cytotoxicity or any inflammatory response. It is found that the elution of a calcium ion from an artificial bone material for transplantation which contains a calcium-containing substance can be prevented effectively by subjecting the carrier to a surface treatment or adding a surface-treating agent to the carrier. It is also found that the induction of cytotoxicity can be prevented and the induction of an inflammatory response can also be prevented by using the above-mentioned carrier having controlled calcium ion elution.
Abstract: This invention relates to a composite comprising carbon nanotubes coated with a polymer, wherein the polymer comprises at least one hydrophobic monomer unit. This invention also relates to a process for the production of a composite comprising a polymer and carbon nanotubes.
Abstract: A method for culturing hepatocytes, wherein hepatocytes embedded in an extracellular matrix is placed on a gas-permeable membrane and the hepatocytes are cultured while being supplied with oxygen from the gas-permeable membrane side. By this, the polarity in the hepatocytes can be induced and a bile canaliculus can be formed in a short period of time. Further, the formed polarity can be maintained for a longer period.
Type:
Grant
Filed:
July 28, 2010
Date of Patent:
December 9, 2014
Assignees:
The University of Tokyo, Mitsubishi Chemical Medience Corporation
Abstract: A method for manufacturing a semiconductor light emitting device includes forming a lower cladding layer over a GaAs substrate; forming a quantum dot active layer over the lower cladding layer; forming a first semiconductor layer over the quantum dot active layer; forming a diffraction grating by etching the first semiconductor layer; forming a second semiconductor layer burying the diffraction grating; and forming an upper cladding layer having a conductive type different from that of the lower cladding layer over the second semiconductor layer, wherein the processes after forming the quantum dot active layer are performed at a temperature not thermally deteriorating or degrading quantum dots included in the quantum dot active layer.
Type:
Grant
Filed:
May 21, 2013
Date of Patent:
December 9, 2014
Assignees:
Fujitsu Limited, The University of Tokyo
Abstract: A blood oxygenator includes an integral pneumatic pump disposed substantially within a housing thereof, an inlet blood flow redirector, and an outflow blood collector. An atrium provided at an inlet of the oxygenator promotes even delivery of blood to the oxygenator. In use, the oxygenator provides an even dispersion of blood therethrough, establishing even perfusion and reducing areas of stagnant blood flow.
Type:
Grant
Filed:
August 13, 2012
Date of Patent:
December 9, 2014
Assignee:
The University of Kentucky Research Foundation
Inventors:
Dongfang Wang, Joseph B. Zwischenberger
Abstract: An electrochromic fiber or fabric is disclosed. The fiber or fabric includes a flexible, electrically conductive fiber, wherein the fiber comprises a non-electrically conductive organic polymer coated with an electrically conductive polymer; and; a layer comprising an electrochromic material disposed on and surrounding the flexible, electrically conductive fiber; wherein the electrically conductive polymer is PEDOT-PSS, poly(vinylpyridine), a poly(thiophene), a poly(pyrrole), a poly(aniline), a poly(acetylene), a poly(p-phenylenevinylene), a sulfonated polythieno[3,4-b]thiophene, polystyrenesulfonate, or a combination thereof. In one embodiment, the fiber or fabric is both flexible and elastic. The fibers and fabrics are of particular utility in electrochromic devices, particularly those which form or are a part of garments.
Type:
Grant
Filed:
August 31, 2011
Date of Patent:
December 9, 2014
Assignee:
The University of Connecticut
Inventors:
Gregory A. Sotzing, Michael A. Invernale
Abstract: The present disclosure relates to methods and systems relating to temperature dependent photoacoustic imaging are provided. In such methods and systems, a tissue sample may be exposed to thermal energy and electromagnetic radiation to generate an acoustic signal, which may be detected. The amplitude of the acoustic signal may be determined and correlated with a tissue property, such as the presence or absence of macrophages or foam cells.
Type:
Grant
Filed:
July 25, 2011
Date of Patent:
December 9, 2014
Assignee:
Board of Regents, The University of Texas System
Inventors:
Stanislav Emelianov, Bo Wang, Jignesh Shah, Konstantin Sokolov, Jimmy Su, Yun-Sheng Chen, Wolfgang Frey
Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule. The composition can also contain one or more pharmaceutically acceptable carriers and/or excipients.
Abstract: Methods and composition for denoising digital camera images are provided herein. The method is based on directly measuring the local statistical structure of natural images in a large training set that has been corrupted with noise mimicking digital camera noise. The measured statistics are conditional means of the ground truth pixel value given a local context of input pixels. Each conditional mean is the Bayes optimal (minimum mean squared error) estimate given the specific local context. The conditional means are measured and applied recursively (e.g., the second conditional mean is measured after denoising with the first conditional mean). Each local context vector consists of only three variables, and hence the conditional means can be measured directly without prior assumptions about the underlying probability distributions, and they can be stored in fixed lookup tables.
Type:
Grant
Filed:
August 12, 2013
Date of Patent:
December 9, 2014
Assignee:
Board of Regents, The University of Texas System
Abstract: Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza.
Type:
Grant
Filed:
January 19, 2012
Date of Patent:
December 9, 2014
Assignee:
The University of British Columbia
Inventors:
Stephen Withers, Andrew Graham Watts, Jin Hyo Kim, Tom Wennekes
Abstract: A wrinkled adhesive surface is prepared by swelling a laterally confined elastomer layer with a polymerizable monomer composition. Swelling the elastomer layer spontaneously produces a wrinkled surface, and the wrinkles are then stabilized by polymerizing the polymerizable monomer composition. The stabilized wrinkled surfaces prepare by the method can exhibit substantially enhanced adhesion relative to smooth surfaces of the same material. The stabilized wrinkled surfaces can also exhibit adhesion that is repeatable through many cycles of contact with and separation from another surface. The adhesive characteristics of the stabilized wrinkled surfaces can be tailored by manipulating the size of the wrinkles.
Type:
Grant
Filed:
May 12, 2009
Date of Patent:
December 9, 2014
Assignee:
The University of Massachusetts
Inventors:
Alfred J. Crosby, Edwin P. Chan, Ryan C. Hayward
Abstract: Embodiments of apparatuses, and methods and systems including apparatuses, configured to be magnetically coupled to a medical device within a body cavity of a patient. Some embodiments include one or more elements comprising at least one of a magnetically-attractive and magnetically-chargeable material; and a bumper extending around the one or more elements and configured to reduce the strength of a magnetic field of the one or more elements.
Type:
Application
Filed:
April 3, 2014
Publication date:
December 4, 2014
Applicant:
Board of Regents, The University of Texas System
Inventors:
Richard A. BERGS, Heather E. BEARDSLEY, Jeffrey A. CADEDDU, Raul FERNANDEZ, Daniel J. SCOTT
Abstract: A carbon nanotube studded carbon fiber tow and matrix prepreg includes a body comprising a tow of surface fibers and interior bulk fibers. The surface fibers are studded with carbon nanotubes and the carbon fibers are infiltrated with a matrix material.
Type:
Application
Filed:
May 31, 2013
Publication date:
December 4, 2014
Applicants:
Materials Sciences Corporation, The University of Kentucky Research Foundation
Inventors:
Matthew Collins Weisenberger, John Davis Craddock, Richard Foedinger
Abstract: A system, method and apparatus for controlling boost and buck-boost converters using input-output linearization and leading-edge modulation is provided. The controller includes a summing circuit connected to the converter to create a third voltage representing a difference between the first voltage and the second voltage. A gain circuit is connected to the summing circuit to adjust the third voltage by an appropriate gain. A modulating circuit is connected to the gain circuit, the converter, the first voltage, the second voltage and the second current to create a control signal based on the first voltage, the second voltage, the adjusted third voltage, the fourth voltage and the first current. The control signal is used to control the converter. Typically, the first voltage is a converter output voltage, the second voltage is a reference voltage, the fourth voltage is a converter input voltage, and first current is a converter inductor current.
Type:
Application
Filed:
August 18, 2014
Publication date:
December 4, 2014
Applicants:
Cirasys, Inc., The Board of Regents, The University of Texas System
Abstract: The antifouling coating is a composite material consisting of fluorinated electroactive bipolymers and magnetic particles. This composite material is coated on a solid surface to make a smooth durable grassy coating. The coating generates electrical current when an electrolytic liquid flows over it, which prevents bacterial cells from attaching to the surface. It prevents virus and protein attachment. It also prevents chemical corrosion of a surface. The composite material itself, and the antifouling method that uses fluoride compounds and electrical current that is generated by the fluid flow are disclosed for a patent. The composite material can be applied to medical devices, biomedical devices, industrial equipment, ship's hulls, food processing equipment, food processors, drinking water distribution systems, and home electrical appliances.