Patents Assigned to The University
  • Method for performing handoff in wireless network
    Patent number: 8838103
    Abstract: A method for minimizing handoff latencies when a handoff is performed in a wireless network. An access point (AP) or base station associated to a current wireless station (STA) allows information required for a reassociation to the STA to be propagated to handoff-capable neighboring APs or base stations. When the STA moves, a neighboring AP or base station performs the reassociation to the STA on the basis of context. When a handoff procedure is performed, the time taken to receive context of a corresponding STA is reduced, such that a fast handoff can be implemented.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: September 16, 2014
    Assignees: Samsung Electronics Co., Ltd., The University of Maryland College Park
    Inventors: In-Sun Lee, Kyung-Hun Jang, Min-Ho Shin, William Albert Arbaugh, Arunesh Mishra
  • Treatment of cancer by inhibition of IGFBPs and clusterin
    Patent number: 8835401
    Abstract: Agents that reduce the amount of IGFBP-2 and/or IGFBP-5 and that are known to be useful in the treatment of cancer result in increased expression of the protein clusterin. Since clusterin can provide protection against apoptosis, this secondary effect detracts from the efficacy of the therapeutic agent. In overcoming this, the present invention provides a combination of therapeutic agents that is useful in the treatment of cancer. The combination includes an agent that reduces the amount of IGFBP-2 and/or IGFBP-5 and that stimulates expression of clusterin as a secondary effect, and an oligonucleotide that is effective to reduce the amount of clusterin in cancer cells. In some embodiments of the invention, the agent that reduces IGFBP-2 and/or IGFBP-5 is a bispecific antisense species. The oligonucleotide may be an antisense oligonucleotide or an RNAi oligonucleotide.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: September 16, 2014
    Assignee: The University of British Columbia
    Inventor: Martin E. Gleave
  • Rapid, interactive editing of massive imagery data
    Patent number: 8836714
    Abstract: A method, a system, and a computer-readable medium are provided which provide interactive editing of image data. Image data is sampled, by a computing device, at a first resolution. The first resolution is lower than a full resolution of the image data. Gradients for the sampled image data are calculated by the computing device. The computing device solves a system equation for color pixel data for each pixel of the sampled image data using the sampled image data and the calculated gradients. The computing device controls a display of the color pixel data on a display.
    Type: Grant
    Filed: October 29, 2010
    Date of Patent: September 16, 2014
    Assignee: The University of Utah Research Foundation
    Inventor: Valerio Pascucci
  • Modifying single proteins (GPCR), ligands, and nanopore surfaces to create binding-induced molecular changes of protein-ligand complexes detected in nanochannel translocation
    Patent number: 8835362
    Abstract: A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: September 16, 2014
    Assignees: International Business Machines Corporation, The University of Melbourne, Florey Institute of Neuroscience and Mental Health
    Inventors: Matthew Downtown, Natalie Gunn, Stefan Harrer, Priscilla Rogers, John Wagner, Ross Bathgate, Daniel James Scott, Stan Skafidas
  • Extraction process for reactive metal oxides
    Patent number: 8834600
    Abstract: The present invention relates to a zero-waste process for extraction of alumina from different types of bauxite ores and red mud residues and of titanium dioxide from ilmenite. Iron oxide is first reduced to metallic iron above the melting point of C-saturated cast iron alloy which yields a high-C iron alloy and an Al and Ti metal oxide rich slag which is then treated with alkali carbonate to form alkali aluminates and titanates. The alkali aluminates are separated by water leaching from which the hydroxide of alumina is precipitated by bubbling C02. The residue from water leaching is treated with sulphuric acid and Ti02 is precipitated via a hydrolysis route. The process recovers most of the metal values and generates only small quantities of silicious residues at pH 4-5 which can be used for soil conditioning.
    Type: Grant
    Filed: June 11, 2004
    Date of Patent: September 16, 2014
    Assignee: The University of Leeds
    Inventors: Animesh Jha, Pailo Antony Malpan, Vilas Dattatray Tathavadkar
  • Multi-wavelength diagnostic imager
    Patent number: 8838211
    Abstract: The present invention is a multi-wavelength diagnostic imager. In one embodiment, the present invention includes an apparatus and method for noninvasive evaluation of a target versus a non-target, comprising: one or more light sources having at least one emission spectra directed at the target wherein the position, orientation and intensity of light sources is varied to control near-surface reflectance and are directed at less than the entire target; and one or more detectors positioned to capture light reflected from the target into two or more spatial images of the target at two or more times, wherein the spatial images are used to distinguish between the target and the non-target.
    Type: Grant
    Filed: April 30, 2009
    Date of Patent: September 16, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jose Melendez, James Watson, John Michael DiMaio, Roma Moza
  • ?-mannosylceramide and stimulation of NKT cell anti-tumor immunity
    Patent number: 8835613
    Abstract: ?-mannosylceramides or salts or solvates thereof in a pharmaceutically acceptable carrier, for use as a Type I NKT cell agonist in conjunction with a therapeutically effective amount of ?-galactosylceramide or a salt or a solvate thereof, and/or at least one or more T-cell co-stimulatory molecules, disclosed. Compositions comprising ?-mannosylceramide, as well as methods of treatment of tumors are also provided.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: September 16, 2014
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The University of Birmingham, of Edgbaston
    Inventors: Jay A. Berzofsky, Jessica J. O'Konek, Masaki Terabe, Petr Illarionov, Gurdyal S. Besra
  • Methods to increase the photostability of dyes
    Patent number: 8835632
    Abstract: The presently disclosed subject matter provides dyes having an improved photostability, biosensors comprising such dyes, and methods of use thereof, including methods for detecting target molecules in a sample under test and for live-cell imaging. The dyes can include a binding member, including a biomolecule or fragments thereof, which can interact with target molecules of interest and can be specific to a given conformational state or covalent modification, e.g., phosphorylation, of the target molecule. The presently disclosed dyes can be used for detecting changes in the binding, conformational change, or posttranslational modification of the target molecule.
    Type: Grant
    Filed: June 20, 2008
    Date of Patent: September 16, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Klaus Hahn, Alexei Toutchkine
  • METHODS, SYSTEMS, AND DEVICES FOR TREATING TINNITUS WITH VNS PAIRING
    Publication number: 20140257430
    Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicants: MicroTransponder, Inc., The Board of Regents, The University of Texas System
    Inventors: Michael P. KILGARD, Navzer ENGINEER, David Michael PIERCE
  • Rapid Pulse Electrohydraulic (EH) Shockwave Generator Apparatus and Methods for Medical and Cosmetic Treatments
    Publication number: 20140257144
    Abstract: Apparatuses and methods for electrohydraulic generation of shockwaves at a rate of between 10 Hz and 5 MHz, and/or that permit a user to view a region of a patient comprising target cells during application of generated shockwaves to the region. Methods of applying electro-hydraulically generated shockwaves to target tissues (e.g., for reducing the appearance of tattoos, treatment or reduction of certain conditions and/or maladies).
    Type: Application
    Filed: March 13, 2013
    Publication date: September 11, 2014
    Applicants: Board of Regents, The University of Texas System, Soliton, Inc.
    Inventors: Christopher C. Capelli, Robert Crowley
  • METHODS, SYSTEMS, AND DEVICES FOR TREATING TINNITUS WITH VNS PAIRING
    Publication number: 20140257132
    Abstract: A method of treating tinnitus comprising measuring a patient's hearing, determining the patient's hearing loss and the patient's tinnitus frequency using the measurements of the patient's hearing, programming a clinical controller with the measurements of the patient's hearing, selecting a plurality of therapeutic tones, where the therapeutic tones are selected to be at least a half-octave above or below of the patient's tinnitus frequency, setting an appropriate volume for each of the plurality of tones, repetitively playing each of the plurality of therapeutic tones, and pairing a vagus nerve stimulation pulse train with each playing of a therapeutic tone, thereby reducing the patient's perception of tinnitus.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicants: MicroTransponder, Inc., The Board of Regents, The University of Texas System
    Inventors: Michael P. KILGARD, Navzer ENGINEER, David Michael PIERCE
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF HUNTINGTON'S DISEASE
    Publication number: 20140256578
    Abstract: Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.
    Type: Application
    Filed: February 6, 2014
    Publication date: September 11, 2014
    Applicant: The University of British Columbia
    Inventors: Michael HAYDEN, Jeffrey CARROLL, Simon WARBY
  • SYSTEM FOR REDUCING TORQUE RIPPLE IN AN ELECTRIC MOTOR
    Publication number: 20140253002
    Abstract: A motor control system is provided. The motor control system includes a motor, a position sensor, a current sensor, and a control module. The motor has a rotor and a stator. The motor generates an output torque based on a phase current applied to the motor. The output torque generated by the motor creates a torque ripple that is within a predefined range. The position sensor monitors the motor to determine a rotor position. The current sensor monitors the motor to determine the phase current. The control module is in communication with the motor, the position sensor, and the current sensor. The control module includes a lookup table that stores values of phase current commands. The control module determines a phase current command from the lookup table based on the rotor position and the phase current.
    Type: Application
    Filed: March 11, 2013
    Publication date: September 11, 2014
    Applicants: The University of Akron, Steering Solutions IP Holding Corporation
    Inventors: Rajib Mikail, Mohammad S. Islam, Yilmaz Sozer, Iqbal Husain
  • -benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents
    Patent number: 8829033
    Abstract: A first aspect of the invention is a compound (sometimes also referred to herein as an “active agent” or “active compound”) of Formula Ia, or more particularly Formula Ib, or a pharmaceutically acceptable salt or prodrug thereof. Compositions thereof and methods of using the same (e.g. for the treatment of a neurological disease) are also described.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: September 9, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Harold L. Kohn, Christophe Salomé, Elise Salomé-Grosjean
  • Reticulated mesh arrays and dissimilar array monoliths by additive layered manufacturing using electron and laser beam melting
    Patent number: 8828311
    Abstract: Compositions and methods for making a three dimensional structure comprising: designing a three-dimensional structure; melting the three-dimensional structure from two or more layers of a metal powder with a high energy electron or laser beam is described herein. The position where the metal is melted into the structure is formed along a layer of metal powder, wherein the location and intensity of the beam that strikes the metal layer is based on the three-dimensional structure and is controlled and directed by a processor. The instant invention comprises a novel dry state sonication step for removing metal powder that is not melted from the three dimensional structure.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: September 9, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Frank Medina, Lawrence Murr, Ryan Wicker, Sara Gaytan
  • Core muscle strengthening
    Patent number: 8827880
    Abstract: The method and system of this invention provides for core muscle strengthening. The method comprises the step of: providing an apparatus (10) that provides resistance and assistance during core muscle training using dynamic therapeutic movement for chest, back, abdominal and leg musculature to strengthen and condition muscles of the axial skeleton and lower extremities of a performing user. In one embodiment, the method also is for non-invasive physical therapy.
    Type: Grant
    Filed: January 24, 2013
    Date of Patent: September 9, 2014
    Assignees: The University of Toledo, The Turning Point LLC
    Inventors: Vijay K. Goel, Kenneth Germano, F. Alan Schultheis, David Dick
  • Compositions and methods for vaccinating against HSV-2
    Patent number: 8828408
    Abstract: This invention relates to therapeutic polynucleotide compositions and methods for systemic immune activation which are effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in mammals. The polynucleotide compositions are particularly effective for protecting mammals from herpes simplex virus (HSV), such as HSV VP13/14 polypeptides.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 9, 2014
    Assignees: Vical Incorporated, The University of Washington
    Inventors: Adrian Vilalta, Michal Margalith, Lichun Dong, David M. Koelle
  • PARP substrates and biomarkers
    Patent number: 8828672
    Abstract: PARylated proteins are enriched by treating cell lysates comprising PARylated proteins and DNA/RNA with an endonuclease that cleaves the DNA/RNA but not the PAR; and separating the PARylated proteins from the cleaved DNA/RNA. PARylation sites are labeled by eluting PARylated proteins from a PAR-affinity substrate with a nucleophilic amine exchange reactant, wherein the reactant labels PARylation sites of the proteins. Specific binding agents are identified by screening compounds for specific binding to a PARylated protein disclosed herein; and identifying one of the compounds as a specific binder of the protein. Antibodies which specifically bind PARylation sites are also disclosed.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: September 9, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventor: Yonghao Yu
  • Nanostructure assemblies, methods and devices thereof
    Patent number: 8828792
    Abstract: Disclosed herein are methods for assembling nanostructures. The assembling methods include contacting the plurality of nanostructures to a substrate having one or more discontinuities. At least a portion of the plurality of nanostructures assemble adjacent to the discontinuity, the assembled nanostructures including at least one nanostructure having a bridging, molecule. Devices, such as field-effect transistors, are also disclosed.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: September 9, 2014
    Assignee: The Trustees of The University of Pennsylvania
    Inventors: Marija Drndic, Michael D. Fischbein
  • Back contact buffer layer for thin-film solar cells
    Patent number: 8829342
    Abstract: A photovoltaic cell structure is disclosed that includes a buffer/passivation layer at a CdTe/Back contact interface. The buffer/passivation layer is formed from the same material that forms the n-type semiconductor active layer. In one embodiment, the buffer layer and the n-type semiconductor active layer are formed from cadmium sulfide (CdS). A method of forming a photovoltaic cell includes the step of forming the semiconductor active layers and the buffer/passivation layer within the same deposition chamber and using the same material source.
    Type: Grant
    Filed: October 19, 2010
    Date of Patent: September 9, 2014
    Assignee: The University of Toledo
    Inventors: Alvin D. Compaan, Victor V. Plotnikov