Abstract: An electrode for use in an organic optoelectronic device is provided. The electrode includes a thin film of single-wall carbon nanotubes. The film may be deposited on a substrate of the device by using an elastomeric stamp. The film may be enhanced by spin-coating a smoothing layer on the film and/or doping the film to enhance conductivity. Electrodes according to the present invention may have conductivities, transparencies, and other features comparable to other materials typically used as electrodes in optoelectronic devices.
Type:
Grant
Filed:
October 22, 2012
Date of Patent:
September 9, 2014
Assignee:
The University of Southern California
Inventors:
Daihua Zhang, Koungmin Ryu, Xiaolei Liu, Evgueni Polikarpov, James Ly, Mark E. Thompson, Chongwu Zhou, Cody Schlenker
Abstract: Methods of making nano-scale structures with geometric cross-sections, including convex or non-convex cross-sections, are described. The approach may be used to directly pattern substrates and/or create imprint lithography templates or molds that may be subsequently used to directly replicate nano-shaped patterns into other substrates, such as into a functional or sacrificial resist to form functional nanoparticles.
Type:
Grant
Filed:
November 7, 2011
Date of Patent:
September 9, 2014
Assignees:
Molecular Imprints, Inc., Board of Regents, The University of Texas System
Inventors:
Sidlgata V. Sreenivasan, Vikramjit Singh, Frank Y. Xu, Byung-Jin Choi
Abstract: The present invention generally relates to the field of water treatment, and in particular to industrial processes which generate aqueous solutions containing thiocyanate (SCN). The invention particularly relates to processes for treating aqueous solutions containing SCN and more specifically treatment processes to extract and remove SCN from said aqueous solutions.
Type:
Grant
Filed:
August 12, 2011
Date of Patent:
September 9, 2014
Assignee:
The University of Melbourne
Inventors:
Spas Dimitrov Kolev, Robert Walter Cattrall, Youngsoo Cho
Abstract: Compounds of formula (I): in which R1, R2, R3, R3?, R4, R5, R6, R6?, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, A, D, X, Y, and Z are defined in the specification. Also disclosed is a method of using one of the compounds to lower the blood cholesterol level and treat cancer, atherosclerosis, diabetes, Alzheimer's disease, and corneal arcus.
Type:
Grant
Filed:
July 29, 2010
Date of Patent:
September 9, 2014
Assignee:
The University of Chicago
Inventors:
Dacheng Peng, John Kokontis, Richard Hiipakka, Shutsung Liao
Abstract: Digital communication coding methods for designing protograph-based bit-interleaved code modulation that is general and applies to any modulation. The general coding framework can support not only multiple rates but also adaptive modulation. The method is a two stage lifting approach. In the first stage, an original protograph is lifted to a slightly larger intermediate protograph. The intermediate protograph is then lifted via a circulant matrix to the expected codeword length to form a protograph-based low-density parity-check code.
Type:
Grant
Filed:
November 29, 2011
Date of Patent:
September 9, 2014
Assignees:
California Institute of Technology, Board of Regents, The University of Texas System
Inventors:
Thuy V. Nguyen, Aria Nosratinia, Dariush Divsalar
Abstract: Although it can be farnesylated, the mutant lamin A protein expressed in Hutchinson Gilford Progeria Syndrome (HGPS) cannot be defarnesylated because the characteristic mutation causes deletion of a cleavage site necessary for binding the protease ZMPSTE24 and effecting defarnesylation. The result is an aberrant farnesylated protein (called “progerin”) that alters normal lamin A function as a dominant negative, as well as assuming its own aberrant function through its association with the nuclear membrane. The retention of farnesylation, and potentially other abnormal properties of progerin and other abnormal lamin gene protein products, produces disease. Farnesyltransferase inhibitors (FTIs) (both direct effectors and indirect inhibitors) will inhibit the formation of progerin, cause a decrease in lamin A protein, and/or an increase prelamin A protein. Decreasing the amount of aberrant protein improves cellular effects caused by and progerin expression.
Type:
Grant
Filed:
April 4, 2013
Date of Patent:
September 9, 2014
Assignees:
Progeria Research Foundation, Inc., The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of North Carolina at Chapel Hill, The Regents of the University of Michigan
Inventors:
Leslie B. Gordon, Francis S. Collins, Thomas Glover, Michael W. Glynn, Brian C. Capell, Adrienne D. Cox, Channing J. Der
Abstract: This invention provides compositions and methods for treating cancer. More specifically this invention is directed to a targeted retroviral vector comprising a cytokine gene that can be administered either alone or in combination with a targeted retroviral vector comprising a cytocidal gene for treating cancer in a subject. Also provided are a kit or drug delivery system comprising the compositions for use in the methods described.
Abstract: Provided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo.
Abstract: A control server according to an embodiment sorts a plurality of notebook PCs into a plurality of groups so that the total value of the remaining amounts is a value similar to the total value of the remaining amounts of the rechargeable batteries of a plurality of notebook PCs included in a different group. The control server according to the embodiment performs local search individually on the sorted groups, and generates a control plan for the individual notebook PCs.
Type:
Application
Filed:
February 28, 2014
Publication date:
September 4, 2014
Applicants:
The University of Tokyo, FUJITSU LIMITED
Abstract: A method for preparing a conjugated microporous polymer comprises the coupling of an alkynyl aryl monomer having a plurality of terminal alkyne groups with an iodo- or bromo-aryl monomer having a plurality of halogen atoms in the presence of a palladium (0) catalyst. The conjugated microporous polymer comprises nodes comprising at least one aryl unit and struts comprising at least one alkyne unit and at least one aryl unit, wherein a node is bonded from its aryl unit or units to at least two struts via alkyne units. Such polymers are useful in numerous areas such as separations, controlled release, gas storage and supports for catalysts.
Type:
Application
Filed:
March 7, 2014
Publication date:
September 4, 2014
Applicant:
The University of Liverpool
Inventors:
Andrew Cooper, Jiaxing Jiang, Neil Campbell, Fabing Su, Abbie Trewin
Abstract: A method of forming an implant having a porous tissue ingrowth structure and a bearing support structure. The method includes depositing a first layer of a metal powder onto a substrate, scanning a laser beam over the powder so as to sinter the metal powder at predetermined locations, depositing at least one layer of the metal powder onto the first layer and repeating the scanning of the laser beam.
Type:
Application
Filed:
May 13, 2014
Publication date:
September 4, 2014
Applicants:
The University of Liverpool, Howmedica Osteonics Corp.
Inventors:
Eric Jones, Christopher J. Sutcliffe, Robin Stamp
Abstract: An injectable composite material comprising a fibrous material comprised of a fir biocompatible low melting point polyester dispersed in a host medium comprised of second biocompatible low melting point polyester.
Abstract: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
Type:
Application
Filed:
February 15, 2013
Publication date:
September 4, 2014
Applicants:
University of Saskatchewan, International Vaccine Institute, Dalhousie University, The University of British Columbia
Inventors:
University of Saskatchewan, The University of British Columbia, Dalhousie University, International Vaccine Institute
Abstract: The present invention is a natural, cell-free tissue replacement that does not require difficult or extensive preparation made by washing tissue replacement in a solution including one or more sulfobetaines and an anionic surface-active detergent and washing the tissue replacement in serial solutions of the buffered salt to remove excess detergent. The natural, cell-free tissue replacement may be a nerve graft that supports axonal regeneration, guides the axons toward the distal nerve end and/or is immunologically tolerated. Other forms of the invention are a composition and kit prepared by the method of making a native, cell-free tissue replacement. The present invention may be modified for use in diagnostic, therapeutic, and prophylactic applications.
Type:
Application
Filed:
May 9, 2014
Publication date:
September 4, 2014
Applicant:
Board of Regents, The University of Texas System
Abstract: To provide a fluorescent hydrogel having superior detectability of saccharides such as glucose and minimal invasiveness, a method for producing the same, and a sensor for measuring saccharides using the same. A florescent hydrogel having a structure represented by the following chemical formula 1, a method for producing the same, and a sensor for measuring saccharides using the same.
Type:
Grant
Filed:
September 7, 2011
Date of Patent:
September 2, 2014
Assignees:
Terumo Kabushiki Kaisha, The University of Tokyo
Abstract: Substituted selenophene monomers, and polymers and copolymers having units derived from a substituted selenophene are disclosed. Also provided are methods of making and using the same.
Abstract: Provided herein are inter alia novel compositions and methods having application in a variety of fields including the field of enhanced oil recovery, the cleaning industry as well as groundwater remediation. In particular, the alkoxy carboxylate compounds and mixtures thereof presented herein can be used, inter alia, for the recovery of a large range of crude oil compositions from challenging reservoirs.
Type:
Grant
Filed:
August 29, 2011
Date of Patent:
September 2, 2014
Assignee:
Board of Regents, The University of Texas System
Abstract: The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject.
Type:
Grant
Filed:
November 24, 2010
Date of Patent:
September 2, 2014
Assignee:
The University of North Carolina at Chapel Hill
Abstract: A discharge assembly apparatus for discharging a metered volume of a liquid when used in combination with a liquid-containing, pressurized or pressurizable container includes an actuator assembly incorporating a valve stem having a discharge conduit arrangement with an inlet and an outlet, a metering chamber formed within the valve stem and incorporating a liquid discharge element, an inlet/outlet arrangement, and a housing wherein the valve stem and the inner surface of the housing define a fluid transfer passageway therebetween, the discharge conduit arrangement of the valve stem providing communication between the outlet of the metering chamber and the outlet of the valve stem via the fluid transfer passageway.
Type:
Grant
Filed:
October 8, 2010
Date of Patent:
September 2, 2014
Assignee:
The University of Salford
Inventors:
Ghasem Ghavami-Nasr, Andrew John Yule, Martin Laurence Burby
Abstract: A discharge assembly for discharging a metered volume of a liquid held in a pressured container includes an elongate tubular housing, a valve stem having a body locating within the housing, a chamber provided within the body of the valve stem and having a liquid inlet, and a liquid discharge element moveable along the chamber from a liquid primed position to a liquid discharged position to effect discharge of the metered volume of liquid, wherein a second fluid transfer passageway is formed along the outside of the valve stem between the inlet of the housing and the first fluid transfer passageway, and a seal is provided for relative sliding movement onto a seat as the valve stem moves to close the second fluid transfer passageway to fluid flow.
Type:
Grant
Filed:
October 8, 2010
Date of Patent:
September 2, 2014
Assignee:
The University of Salford
Inventors:
Ghasem Ghavami-Nasr, Andrew John Yule, Martin Laurence Burby