Abstract: A method of producing bismuth oxyhalide quantum dots without heat. The method is a one-pot method that includes synthesizing bismuth oxyhalide quantum dots at room temperature. The method results in quantum dots preferably having bismuth and halide in a molar ratio of 1:1. Further, the bismuth oxyhalide quantum dots produced demonstrate excellent photocatalytic activity in the visible light spectrum and possess improved surface characteristics.
Type:
Grant
Filed:
December 4, 2024
Date of Patent:
April 15, 2025
Assignee:
IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY
Inventors:
Babiker Y. Abdulkhair, Faisal K. Algethami, Mohamed R. Elamin
Abstract: Provided herein are methods for treating cancer in a subject comprising administering an ICB therapy to a subject having cancer, wherein the subject's cancer comprises one or more mutations in two or more genes associated with responsiveness to immune checkpoint blockade (ICB).
Abstract: A precise cardiac data reconstruction method is provided, which may also be referred to herein as radar cardiography (RCG). RCG can reconstruct cardiac data, such as heart rate and/or electrocardiogram (ECG)-like heartbeat waveform signals wirelessly by using advanced radar signal processing techniques. For example, heartbeat and related characteristics can be monitored by isolating cardiovascular activity from strong respiratory interference in spatial spaces: azimuth and elevation. This results in significant improvements to pulse signal-to-noise-ratio (SNR) compared to conventional approaches, facilitating heart-rate variability (HRV) analysis.
Type:
Grant
Filed:
March 19, 2020
Date of Patent:
April 15, 2025
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A switchable liquid crystal grating cell, and methods for manufacturing the above. The switchable liquid crystal grating cell comprises a pair of switchable liquid crystal grating parts, each switchable liquid crystal grating part comprises a substrate; a conductive layer on the substrate; and a photoalignment layer with an alignment pattern above the conductive layer on the substrate, the alignment pattern having first and second types of domains, the first type of domain having a first uniform alignment direction, the second type of domain having a second uniform alignment direction that is reoriented at a predetermined angle to the first uniform alignment direction, the predetermined angle is 85°-95°, and a liquid crystal layer sandwiched between the pair of switchable liquid crystal grating parts, wherein an alignment pattern on a top surface is arranged to be shifted relative to the other alignment pattern on a bottom surface.
Type:
Grant
Filed:
October 31, 2023
Date of Patent:
April 15, 2025
Assignee:
The Hong Kong University of Science and Technology
Abstract: Affibody polypeptides that specifically bind to B7-H3 are provided. Exemplary anti-B7-H3 affibodies are provided. The affibody polypeptides specifically recognize and bind to B7-H3 with high affinity.
Type:
Grant
Filed:
August 22, 2019
Date of Patent:
April 15, 2025
Assignee:
REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventors:
Lotfi Abou-Elkacem, Juergen Karl Willmann, Benjamin J. Hackel, Lawrence Arthur Stern, Patrick Samuel Lown, Amelie Margarete Marianne Lutz, Rakesh Kumar Bam
Abstract: The present disclosure provides a method for detecting and tracking a low-observable target with a boost-to-glide trajectory under a condition of slant range ambiguity, and belongs to the field of detection and tracking of near-space hypersonic targets. The method includes: configuring an alternating pulse repetition frequency model for radar ranging; defining an extended non-coherent accumulation model in a distance-time plane for target detection; configuring an S-type recursive energy tracking model for target tracking; designing a recursive energy filter, conducting update by recursive energy to keep target tracking at a high signal-to-noise ratio, and obtaining a target trajectory by using a filter algorithm. According to the method of the present disclosure, pulse repetition frequencies within a same sampling period are designed to a constant value, so that there is enough energy for coherent accumulation detection.
Type:
Grant
Filed:
November 26, 2024
Date of Patent:
April 15, 2025
Assignee:
Naval Aeronautical University
Inventors:
Xiangyu Zhang, Hongsen Xie, Guochen Ding, Jie Yu, Changwen Zhan, Fengyuan Liu
Abstract: The present invention discloses a RamA transcription factor mutant for promoting the production of N-acetylglucosamine and use thereof. The mutant is obtained by mutating lysine at position 90 to asparagine and serine at position 92 to lysine in a parent having an amino acid sequence as shown in SEQ ID NO: 2. The present invention provides a genetically engineered strain that overexpresses the RamA transcription factor mutant and increases the production of N-acetylglucosamine. By overexpressing the transcription factor RamA that is involved in the regulation of carbon metabolism, the extracellular accumulation of N-acetylglucosamine is increased, with a maximum concentration reaching 31.5 g/L, which lays a foundation for further metabolic engineering of Corynebacterium glutamicum to produce glucosamine. The method for constructing recombinant Corynebacterium glutamicum of the invention is simple, and convenient in use, and thus has good application prospects.
Abstract: The present invention provides a field effect transistor device and a method for improving the short-channel effect and the output characteristics using the same. The field effect transistor device comprises an active layer comprising a source region, a drain region, and a channel region located between the source region and the drain region; when the device is turned on, an effective channel and an equivalent source and/or equivalent drain away from the effective channel are formed in the channel region, and the field effect transistor device connects the source region with the drain region through the effective channel, and the equivalent source and/or equivalent drain to form an operating current.
Type:
Grant
Filed:
December 1, 2021
Date of Patent:
April 15, 2025
Assignee:
Soochow University
Inventors:
Mingxiang Wang, Lekai Chen, Dongli Zhang, Huaisheng Wang
Abstract: A geopolymer composite including a porous aluminosilicate material, a quaternary ammonium surfactant, and a hydrophobicity modifier that includes dibenzoylmethane. The quaternary ammonium surfactant occupies sodium (Na) vacancies in the porous aluminosilicate material, and the hydrophobicity modifier is disposed on the quaternary ammonium surfactant.
Type:
Grant
Filed:
December 3, 2024
Date of Patent:
April 15, 2025
Assignee:
IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY
Abstract: The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations and at least three degrees of freedom. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices.
Type:
Grant
Filed:
July 6, 2020
Date of Patent:
April 15, 2025
Assignee:
Board of Regents of the University of Nebraska
Inventors:
Shane Farritor, Thomas Frederick, Lou Cubrich
Abstract: Implanted medical devices need a mechanism of immobilization to surrounding tissues, which minimizes tissue damage while providing reliable long-term anchoring. This disclosure relates to techniques for patterning arbitrarily shaped 3D objects and to patterned balloon devices having micro- or nano-patterning on an outer surface of an inflatable balloon. The external pattern can provide enhanced friction and anchoring in an aqueous environment. Examples of these types of patterns are hexagonal arrays inspired by tree frogs, corrugated patterns, and microneedle patterns. The patterned balloon devices can be disposed between an implant and surrounding tissues to facilitate anchoring of the implant.
Type:
Grant
Filed:
April 3, 2023
Date of Patent:
April 15, 2025
Assignee:
Cornell University
Inventors:
Seyedhamidreza Alaie, Simon Dunham, Bobak Mosadegh, James K. Min, Amir Ali Amiri Moghadam
Abstract: The present disclosure is directed to a dental appliance. The dental appliance includes a first band adapted for mounting about a first tooth, such as a second molar, the first band having a mesial hook facing toward a root of the first tooth. A second band is included, the second band adapted for mounting about a second tooth, such as a premolar, wherein the second band has a distal hook facing toward a crown of the second tooth. A spring is secured to, and extends between, the distal and mesial hooks. The spring may be a nickel titanium coil spring and have a length of about 13 mm. Other embodiments include a supportive rigid bar, a bi-lateral arrangement, and a method of applying the dental appliance.
Abstract: A controller for an AC-DC converter including a rectifier circuit that converts AC input voltage into DC output voltage uses control logic to control the rectifier circuit according to two or more operating modes. Each operating mode determines a gain of the rectifier circuit. The controller selects an operating mode from the two or more operating modes based on at least one of an AC input voltage value and a required DC output voltage value. The AC-DC converter provides a wide range of DC output voltage with power factor correction. The controller may be used with AC-DC converter topologies such as boost converter, isolated boost converter, PWM converter, LLC resonant converter, and LCC resonant converter.
Type:
Grant
Filed:
October 26, 2022
Date of Patent:
April 15, 2025
Assignee:
Queen's University at Kingston
Inventors:
Yan-Fei Liu, Binghui He, Yang Chen, Bo Sheng, Wenbo Liu
Abstract: A power storage material is made by using a fiber material of cellulose molecules obtained from wood, plant fibers (pulp), and the like, and capable of storing electric power of direct current and alternating current, and an ultra power storage body has the power storage material. A power storage material includes a fiber mainly including a fiber derived from at least any one of wood, plant fibers (pulp), animals, algae, microorganisms, and microbial products, and having a large number of recesses and protrusions on a surface. The fiber is preferably crystallized/amorphous fibers, is preferably an amorphous fiber having an atomic vacancy, and preferably has a specific surface area of 10 m2/g or more. Preferably, the large number of recesses and protrusions have a diameter of 1 nm to 500 nm. Preferably, the electric resistance is 100 M? or more, and the electric capacity is 5 mF/cm2 or more.
Type:
Grant
Filed:
February 12, 2021
Date of Patent:
April 15, 2025
Assignees:
TOHOKU UNIVERSITY, NIPPON PAPER INDUSTRIES CO., LTD.
Abstract: A hardware trojan detection method is provided including an input and output updating step of updating input and output values of all logic cells by performing computations according to logical expressions of all logic cells included in a netlist to be verified and a detection step of performing hardware trojan detection based on a comparison result of the updated input and output values and a threshold.
Type:
Grant
Filed:
June 23, 2021
Date of Patent:
April 15, 2025
Assignees:
Toshiba Information Systems (JAPAN) Corporation, Waseda University
Inventors:
Shinichi Nagata, Koji Takahashi, Nozomu Togawa, Masaru Oya
Abstract: This disclosure relates to use of cashew nut shell liquid (CNSL) phenolics in the manufacture of molecules having ESIPT character, wherein said molecules are UVA and/or UVB absorbers, and further wherein said molecules are formulated as protectants against UVA and/or UVB radiation. The disclosure extends to use of CNSL in the manufacture of compositions including molecules having ESIPT character for treating and/or preventing sunburn and/or preventing U.V. damage.
Type:
Grant
Filed:
March 12, 2020
Date of Patent:
April 15, 2025
Assignees:
UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG, JOHANNES GUTENBERG UNIVERSITY
Inventors:
Till Opatz, Jonas Kühlborn, Charles B. De Koning, Kennedy J. Ngwira, Quintino A. Mgani
Abstract: A cardiovascular variability parameter can be detected independent of the relative absorption contribution of melanin in biological tissue. A light source and a polarization shaping device can illuminate a biological tissue with a polarized light having an inhomogeneous optical polarization wavefront. A polarization analyzer can receive the polarized light after it has interacted with the biological tissue and output a first and second polarization state. A detection device can have a light detector for detecting the first and second polarization state and at least a processor for detecting data related to the first and second polarization states, determining relative absorptions contributions of superficial and deep components of the biological tissue based on the first and second polarization states, and determining the cardiovascular variability parameter based on the relative absorption contributions of the superficial and deep components.
Abstract: A metal artifact reduction (MAR) method and system for reducing metal artifacts from X-ray images. The method is suitable for CT images generated with metallic elements exterior to a patient being scanned, for example, where external probes are applied to a patient, such as ultrasound probes. The method may be embodied in a computer algorithm for use, for example, in radiotherapy treatment planning and patient positioning procedures. In one application, the disclosed technique improves the dose delivery accuracy in ultrasound-guided cardiac radioablation, making this treatment modality a viable option for cardiac arrhythmias.
Abstract: Provided herein are compounds (e.g., compounds of Formula (I) and Formula (II), that modulate HCN channels, intermembrane proteins that serve as nonselective voltage-gated cation channels in the plasma membranes of heart and brain cells. Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating HCN-related disorders (e.g., pain) with the compounds in a subject, by administering the compounds and/or compositions described herein.
Type:
Grant
Filed:
April 26, 2023
Date of Patent:
April 15, 2025
Assignee:
Cornell University
Inventors:
Gareth R. Tibbs, Peter A. Goldstein, Anthony A. Sauve, Rajendra Uprety, James David Warren, Jr., Rebecca L. Joyce, Dipti N. Barman