Abstract: The invention provides compositions and methods for treating inflammatory diseases, such as cardiac or hepatic inflammatory diseases, involving the use of parasite-derived neurotrophic factor (PDNF), or fragment of PDNF. The invention also provides compositions featuring PDNF, or a fragment thereof, and methods for using such compositions for the proliferation and/or mobilization of a stem cell (e.g., cardiac stem cell) or progenitor cell (e.g., hepatic progenitor cell). In one aspect, the invention provides a method of decreasing inflammation in a nonneuronal tissue of a subject. In another aspect, the invention provides a method of decreasing inflammation in a cardiac, liver, pancreas, or gastrointestinal tissue of a subject. In still another aspect, the invention provides a method of increasing expression of an anti-inflammatory factor in a non-neuronal cell or tissue.
Abstract: In a method for communicating among a plurality of nodes in a content-centric networking environment, each of a plurality of nodes selects at least one relay node based on topology information on neighbor nodes adjacent within 2 hops from itself. Each of the selected relay nodes determines whether itself is a publisher relay node. Each of the determined publisher relay nodes generates a multi-hop content announce (CA) message including content information of its own 1-hop neighbor nodes, and broadcasts the multi-hop CA message to the plurality of nodes through the selected relay nodes.
Type:
Grant
Filed:
March 9, 2015
Date of Patent:
August 29, 2017
Assignee:
AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors:
Young Bae Ko, Jae Bum Kim, Daewook Shin
Abstract: A CT system and method thereof are disclosed. The system includes: a conveyor mechanism; a first scanning stage configured to scan the object and generate a first digital signal; a second scanning stage spaced from the first scanning stage at a preset distance in a direction of the object's movement; a processing device configured to reconstruct a CT image of the object at a first image quality based on the first digital signal, and analyze the CT image; and a control device configured to adjust a scanning parameter of the second scanning stage based on an analysis result of the processing device to cause the second scanning stage to output a second digital signal. The processing device reconstructs a CT image of the object at a second image quality higher than the first image quality at least based on the second digital signal. The system takes full advantage of the distributed ray sources which replace the normal slip ring technology.
Type:
Grant
Filed:
December 19, 2014
Date of Patent:
August 29, 2017
Assignees:
TSINGHUA UNIVERSITY, NUCTECH COMPANY LIMITED
Inventors:
Li Zhang, Zhiqiang Chen, Qingping Huang, Xin Jin, Yunda Sun, Le Shen, Ji Zhao
Abstract: A processing system and a confocal processing method for confocally emitting and receiving ultrasound. Firstly, a first driving electrical signal is generated. Then, at least one first ultrasound signal having a main frequency is emitted to a reflection position according to the first driving electrical signal. With an object at the reflection position, the first ultrasound signal is reflected to form at least one second ultrasound signal. Then, a first analyzed signal whose frequency lower than the main frequency is retrieved from the second ultrasound signal, and other signals are eliminated from the second ultrasound signal, and the first analyzed signal is converted into at least one first analogous signal. Finally, first energy of a first fixed bandwidth of the first analyzed signal is retrieved by the first analogous signal. The method stops generating the first driving electrical signal when the first energy is larger than a predetermined value.
Abstract: This invention provides a method of treating lung cancer including administering a therapeutically effective amount of a compound of 0089-0022 formula I to a subject in need thereof. The compound activates pyruvate kinase M2 isoform (PKM2) to treat the lung cancer. In one example, the lung cancer is Non-Small Cell Lung Cancer (NSCLC).
Type:
Grant
Filed:
January 16, 2017
Date of Patent:
August 29, 2017
Assignee:
Macau University of Science and Technology
Inventors:
Liang Liu, Lai-Han Elaine Leung, Xiao-Jun Yao, Run-Ze Li
Abstract: A hyaluronic acid conjugates including hyaluronic acid, a disulfide bond-containing crosslinking agent, and a cationic, amphiphilic polymer; a hyaluronic acid-nucleic acid complex in which a nucleic acid is bound to the hyaluronic acid conjugate; a composition in which the hyaluronic acid-nucleic acid complexes are crosslinked with each other; a nucleic acid delivery composition including the hyaluronic acid-nucleic acid complex; and a method of nucleic acid delivery using the hyaluronic acid-nucleic acid complex.
Type:
Grant
Filed:
April 1, 2014
Date of Patent:
August 29, 2017
Assignees:
SAMSUNG ELECTRONICS CO., LTD., RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventors:
Hyun-Ryoung Kim, Jae Hyung Park, Hong Yeol Yoon
Abstract: A CMOS-based process for manufacturing a semiconductor gas sensor includes the steps of: I) providing a semi-product, II) etching a substrate to remove a portion of the substrate and a portion of a first insulation layer so as to form a gas-sensing cavity, thereby to expose at least one sensing electrode; and III) depositing a gas-sensitive layer to cover the at least one sensing electrode.
Abstract: The various embodiments disclosed herein relate to improved robotic surgical systems, including robotic surgical devices having improved arm components and/or biometric sensors, contact detection systems for robotic surgical devices, gross positioning systems and devices for use in robotic surgical systems, and improved external controllers and consoles.
Type:
Grant
Filed:
March 13, 2014
Date of Patent:
August 29, 2017
Assignee:
Board of Regents of the University of Nebraska
Inventors:
Shane Farritor, Thomas Frederick, Joe Bartels, Eric Markvicka, Jack Mondry
Abstract: The present disclosure relates to a process for reducing particle agglomeration and/or increasing porosity of agglomerated particles, a method for enhancing dispersion of nanoparticles in a polymer matrix, and thermoplastic or thermoset nanocomposites comprising nanoparticles.
Type:
Grant
Filed:
April 14, 2015
Date of Patent:
August 29, 2017
Assignee:
THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
Abstract: A method of preparing silver nanoparticles, including silver nanorings. A zinc oxide thin film is formed initially by direct-current sputtering of a zinc target onto a substrate. A silver thin film is then formed by a similar sputtering technique, of a silver target onto the zinc oxide thin film. After that, the silver thin film is subject to an annealing treatment. The temperature, duration and atmosphere of the annealing treatment can be varied to control the average particle size, average distance between particles (density), particle size distribution of the silver nanoparticles. In at least one embodiment, silver nanoparticles of ring structure are produced.
Type:
Grant
Filed:
February 26, 2015
Date of Patent:
August 29, 2017
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Qasem Ahmed Drmosh, Mohammad Kamal Hossain, Nouar Amor Tabet
Abstract: Disclosed herein is an interference recognition-based D2D resource allocation method that uses a base station in a cellular system which includes the base station, a plurality of cellular terminals being in a cell that the base station covers, and a plurality of D2D terminals, including: receiving information of a resource block of a least interference amount that a D2D receiving terminal obtains through resource search and information of search time of the resource search from the D2D receiving terminal; obtaining information of a cellular terminal corresponding to the received resource block and the search time among the plurality of cellular terminals from resource scheduling information storing allocation information of the resource block depending on time per each cellular terminal; and simultaneously allocating frequency resource of the cellular terminal to the D2D receiving terminal and a D2D transmitting terminal by using resource scheduling information corresponding to the obtained cellular terminal.
Type:
Grant
Filed:
September 25, 2015
Date of Patent:
August 29, 2017
Assignee:
SOONGSIL UNIVERSITY RESEARCH CONSORTIUM TECHNO-PARK
Inventors:
Oh-Soon Shin, Gil Mo Kang, Hyeon Min Kim
Abstract: A lat pulldown fitness device includes a base, a magnetorheological fluid (MRF) resistance provider, a motor, a gear train, pulleys, a cable assembly, a pulldown bar and a controller. The MRF resistance provider and the motor provide a resistance functioning as a load weight of pulling down the pulldown bar. The controller controls a current input to the MRF resistance provider to change the strength of the resistance generated from the MRF resistance provider. During a workout, the resistance provided by the lat pulldown fitness device is changeable precisely, conveniently, and quickly. Unlike its conventional counterparts which require bumper plates for use as weights, the lat pulldown fitness device is not limited to weight adjustment based on unit bumper plate but features plenty choices and controllable resolution in terms of strength of training. The MRF resistance provider is more compact and lightweight than its conventional counterparts.
Type:
Grant
Filed:
December 5, 2014
Date of Patent:
August 29, 2017
Assignee:
NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY
Abstract: A catalytic process for synthesizing an ester compound, and a catalytic process for synthesizing an amide compound, wherein a solid-supported palladium catalyst is used to catalyze an alkoxycarbonylation reaction of an aryl halide to form the ester compound, or to catalyze an aminocarbonylation reaction of an aryl halide to form the amide compound. Various embodiments of each of the processes are also provided.
Type:
Grant
Filed:
August 12, 2016
Date of Patent:
August 29, 2017
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Bassam M. El Ali, Mansur B. Ibrahim, Rami K. Suleiman
Abstract: This disclosure describes, in one aspect, a composition that generally includes an xNA molecule comprising at least six nucleotides, in an amount effective to improve at least one indicator of myocyte function and a pharmaceutically acceptable carrier. In another aspect, this disclosure describes a method of treating cardiac disease. Generally, the method includes administering to a subject a composition that includes an xNA molecule having at least six nucleotides, in an amount effective to improve at least one indicator of myocyte function, and a pharmaceutically acceptable carrier. In another aspect, this disclosure describes a method for evaluating the efficacy of treatment of cardiac disease. Generally, the method includes administering to a subject a composition that includes a first xNA molecule comprising a predetermined length in an amount effective to increase myocyte relaxation, then selecting a predetermined length of a second xNA molecule for at least one subsequent treatment.
Type:
Grant
Filed:
February 29, 2016
Date of Patent:
August 29, 2017
Assignee:
REGENTS OF THE UNIVERSITY OF MINNESOTA
Inventors:
Michael T. Bowser, Gianluigi Veglia, Meng Jing, Raffaello Verardi, Joseph M. Metzger, Brian Raymond Thompson
Abstract: A staircase avalanche photodiode with a staircase multiplication region composed of an AlInAsSb alloy. The photodiode includes a buffer layer adjacent to a substrate and an avalanche multiplication region adjacent to the buffer layer, where the avalanche multiplication region includes a graded AlInAsSb alloy grown lattice-matched or psuedomorphically strained on either InAs or GaSb. The photodiode further includes a photoabsorption layer adjacent to the avalanche multiplication region, where the photoabsorption layer is utilized for absorbing photons. By utilizing AlInAsSb in the multiplication region, the photodiode exhibits a direct bandgap over a wide range of compositions as well as exhibits large conduction band offsets much larger than the smallest achievable bandgap and small valance band offsets. Furthermore, the photodiode is able to detect extremely weak light with a high signal-to-noise ratio.
Type:
Grant
Filed:
June 17, 2016
Date of Patent:
August 29, 2017
Assignees:
Board of Regents, The University of Texas System, University of Virginia Patent Foundation
Inventors:
Seth Bank, Scott Maddox, Wenlu Sun, Joe Campbell
Abstract: In one embodiment, communicating robot intentions to human beings involves determining movements that a robot will make to complete a task, visually communicating a long-term intention of the robot that provides an indication of the movements the robot will make in completing the task, and visually communicating a short-tem intention of the robot that provides an indication of a movement of the robot will make within the next few seconds in working toward completing the task.
Type:
Grant
Filed:
November 16, 2012
Date of Patent:
August 29, 2017
Assignee:
University of South Florida
Inventors:
Yu Sun, Michael David Coovert, Ivan Shindev
Abstract: An optical device including a shaped electrode on a substrate thereof utilizes total internal reflection to provide improved transmission of electromagnetic radiation (‘light’) to the substrate compared to standard electrode designs that involve flat electrode surfaces. Redirection of incident light by a tilted or otherwise shaped contact or material added on the contact provides otherwise reflected light to an open surface region of the substrate. Optional plasmon mediated focusing of incident p-polarized light may be realized.
Type:
Grant
Filed:
July 24, 2015
Date of Patent:
August 29, 2017
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: Systems, methods, and devices for encoding and decoding data packets for transmission across a data network. To encode, data packets are first subjected to a an outer code process to result in outer coded packets. The outer coded packets are then divided into generations or groups of outer coded packets, each group or generation having an equal number of packets. Output packets are then created by forming random linear combinations of the outer coded packets from a specific generation or group of outer coded packets. The coefficients for the various elements of each linear combination is selected from a Galois field of values. To decode the incoming packets, enough packets are received until an iterative decoding process can be initiated.
Type:
Grant
Filed:
June 18, 2014
Date of Patent:
August 29, 2017
Assignee:
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA