Abstract: A method and system for wastewater treatment based on dissolved oxygen control by a fuzzy neural network, the method for wastewater treatment comprising the following steps: (1) measuring art inlet water flow rate, an ORP value in an anaerobic tank, a DO value in an aerobic tank, an inlet water COD value, and an actual outlet water COD value; (2) collecting the measured sample data and sending them via a computer to a COD fuzzy neural network predictive model, so as to establish an outlet water COD predicted value, (3) comparing the outlet COD predicted value with the outlet water COD set value, so as to obtain an error and an error change rate, and using them as two input variables to adjust a suitable dissolved oxygen concentration. Accordingly, the on-line prediction and real-time control of dissolved oxygen wastewater treatment are achieved.
Type:
Grant
Filed:
September 22, 2011
Date of Patent:
August 29, 2017
Assignee:
SOUTH CHINA UNIVERSITY OF TECHNOLOGY
Inventors:
Jinquan Wan, Mingzhi Huang, Yongwen Ma, Yan Wang
Abstract: Antimicrobial compositions comprising a terpenoid in combination with an antimicrobial agent are provided. In addition, uses of such compositions in various applications involving preventing, combating or treating microbial infections, or preventing microbial growth or establishment are provided.
Type:
Grant
Filed:
September 10, 2010
Date of Patent:
August 29, 2017
Assignee:
UNIVERSITY OF SURREY
Inventors:
Franciscus Antonius Anna Maria De Leij, Mina Kalantarzadeh, Dulcie Mulholland, Tony Hutchings
Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.
Type:
Grant
Filed:
May 18, 2015
Date of Patent:
August 29, 2017
Assignees:
Targeted Growth, Inc., The Regents of the University of California
Inventors:
Jean Paul Olivier, Tom Todaro, Jorge Dubcovsky, Wenjun Zhang
Abstract: Methods, systems, devices and materials are disclosed for implementing a bioaffinity sensor having a self-assembled monolayer interface for detection of a target molecule. In one aspect, a sensor device for detecting a target molecule includes a surface capable of attaching a thiol and a molecular monolayer formed on the surface that includes a molecular capture probe having a thiol region, a linear alkanethiol molecule having one thiol region, and a linear alkanedithiol molecule having two thiol regions, in which the molecular capture probe includes a region for receiving a target substance having a complimentary region that couples with the region of the molecular capture probe to generate a detectable signal.
Type:
Grant
Filed:
January 27, 2012
Date of Patent:
August 29, 2017
Assignee:
The Regents of the University of California
Abstract: Lithium is regarded as the gold standard comparator and benchmark treatment for mania. One of the problems associated with Lithium is its narrow therapeutic window. Recent attempts to find new drugs with similar therapeutic activities have yielded new chemical entities. However, these potential new drugs have yet to match the many bioactivities attributable to lithium's efficacy for the treatment of neuropsychiatric diseases. Consequently, an intense effort for re-engineering lithium therapeutics using cocrystallization is currently underway. The evaluation of pharmacokinetics of previously unexplored lithium salts with organic anions (lithium salicylate and lithium lactate) has found that these lithium salts exhibit profoundly different pharmacokinetics compared to the more common FDA approved salt, lithium carbonate, in rats.
Abstract: A fusion device includes a screw having a head and a shaft. A hollow bone dowel is disposed about the shaft of the screw. The bone dowel is formed from a bone-like, biocompatible, or allograft material.
Type:
Grant
Filed:
June 24, 2014
Date of Patent:
August 29, 2017
Assignee:
The University of Toledo
Inventors:
Vijay K. Goel, Anand K. Agarwal, David Dick
Abstract: Disclosed herein are methods of inducing neuronal outgrowth of a neuron. The methods comprise contacting the neuron with an agent that binds receptor protein tyrosine phosphatase ? (RPTP?), to thereby induce neuronal outgrowth of the neuron. The agent may induces clustering of RPTP? and/or inhibit binding of chondroitin sulfate proteoglycan (CSPG) to RPTP?. Examples of suitable agents are heparan sulfate proteoglycan, heparan sulfate, heparan sulfate oligosaccharides, or heparin oligosaccharides. Additional agents are also disclosed. The neuron can be a CNS neuron or peripheral neuron. Also disclosed herein are methods of treating neuronal injury in a subject comprising, administering to the subject an agent that binds RPTP?. Administration may be to a site of neuronal injury, to thereby induce neuronal outgrowth at the site of neuronal injury.
Type:
Grant
Filed:
February 17, 2012
Date of Patent:
August 29, 2017
Assignees:
PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Inventors:
John G. Flanagan, Yingjie Shen, Edith Yvonne Jones, Alexandru Radu Aricescu, Charlotte Hannah Coles
Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
Type:
Grant
Filed:
November 30, 2015
Date of Patent:
August 29, 2017
Assignees:
Neuralstem, Inc., The Regents of the University of California
Inventors:
Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
Abstract: Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer therapy, or cancer staging in a subject, by evaluating CD33+/HLA-DRlow, CD14+/HLA-DRlow, CD66b+/HLA-DRlow or, CD11b+/HLA-DRlow MDSC for activation of a transcription factor. Transcription factors include, but are not limited to, STAT3, pSTAT3, HIF1?, or C/EBP?. The MDSC phenotype can be CD33+HLA-DRlowHIF1?+/STAT3+, CD14+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD66b+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD33+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD11b+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, or CD11b+HLA-DRlowC/EBP?+. Also provided herein are methods for inducing human MDSC from healthy donor peripheral blood mononuclear cells (PBMC) by co-culturing PBMC with human solid tumor cell lines and subsequently measuring their suppressive ability.
Abstract: A system and method for automated polyp detection in optical colonoscopy images is provided. In one embodiment, the system and method for polyp detection is based on an observation that image appearance around polyp boundaries differs from that of other boundaries in colonoscopy images. To reduce vulnerability against misleading objects, the image processing method localizes polyps by detecting polyp boundaries, while filtering out irrelevant boundaries, with a generative-discriminative model. To filter out irrelevant boundaries, a boundary removal mechanism is provided that captures changes in image appearance across polyp boundaries. Thus, in this embodiment the boundary removal mechanism is minimally affected by texture visibility limitations. In addition, a vote accumulation scheme is applied that enables polyp localization from fragmented edge segmentation maps without identification of whole polyp boundaries.
Type:
Grant
Filed:
April 24, 2015
Date of Patent:
August 29, 2017
Assignees:
Arizona Board of Regents on Behalf of Arizona State University, Mayo Foundation for Medical Education and Research
Inventors:
Nima Tajbakhsh, Suryakanth R. Gurudu, Jianming Liang
Abstract: Provided is a data transmitter including a signal interval determination unit configured to receive a data input signal corresponding to data to be transmitted, determine time intervals between a synchronization signal and a plurality of data signals according to the data input signal, and output interval signals corresponding to the intervals; a trigger generation unit configured to trigger according to an output signal from the signal interval determination unit; and a signal generation unit configured to receive the trigger to generate the synchronization signal and the data signals.
Type:
Grant
Filed:
December 28, 2015
Date of Patent:
August 29, 2017
Assignee:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Inventors:
Tae Wook Kim, Taek Hyun Jung, Geun-Haeng Lee
Abstract: Provided is a disparity correcting device which rapidly corrects disparity information generated on the basis of a left image and disparity information generated on the basis of a right image through a simple configuration, and a method thereof, in stereo vision which generates a 3-dimensional image using a left image and a right image captured from left and right cameras.
Type:
Grant
Filed:
December 31, 2014
Date of Patent:
August 29, 2017
Assignee:
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
Abstract: The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit.
Type:
Grant
Filed:
February 18, 2014
Date of Patent:
August 29, 2017
Assignees:
The Regents of the University of California, Fondazione Istituto Italiano di Technologia, Universita Degli Studi di Urbino “Carlo Bo”, Universita Degli Studi di Parma
Inventors:
Daniele Piomelli, Guillermo Moreno-Sanz, Tiziano Bandiera, Marco Mor, Giorgio Tarzia
Abstract: One example embodiment is a method executed by a microcontroller with a Pulse Width Modulation (PWM) circuit to control a semi-dual-active-bridge (SDAB) converter that includes a first side bridge circuit, a second side bridge circuit and a transformer. The microcontroller determines a current operation mode and a target operation mode of the SDAB converter. The microcontroller determines an optimal ratio and calculates changes of each gating signal that are applied to the first side bridge circuit and the second side bridge circuit respectively.
Type:
Grant
Filed:
November 1, 2016
Date of Patent:
August 29, 2017
Assignee:
Macau University of Science and Technology
Abstract: Printed active origami combines printed electronics with nanomaterial coated polymer based actuators to create active printed structures. The fabrication processes include the step of applying carbon nanomaterial coatings to polymeric films. Products produced by the processes include actuating materials, such as solid state actuators that can be used as active element(s) in a printable active origami robot.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
August 29, 2017
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Mike O'Connell, Brett Yost, Takayuki Nosaka, Chegwei Wang
Abstract: A magnetic resonance system (10), and corresponding method, image a subject using a conversion-free interleaved black and bright blood imaging (cfIBBI) sequence. A MR scanner (12) is controlled to perform a plurality of repetitions of a black blood imaging sequence (52). The black blood imaging sequence (52) includes a tissue nulling sub-sequence followed by a black blood acquisition sub-sequence (56) performed a time interval (TI) after the tissue nulling sub-sequence. The MR scanner (12) is further controlled to, between successive repetitions of the black blood imaging sequence (52), perform a bright blood imaging sequence (54) including the tissue nulling sub-sequence followed by a bright blood acquisition sub-sequence (58) performed the time interval (TI) after the tissue nulling sub-sequence. The time intervals (TI) of the black blood imaging sequence (52) and the bright blood imaging sequence (54) are of the same duration.
Type:
Grant
Filed:
December 12, 2013
Date of Patent:
August 29, 2017
Assignees:
Koninklijke Philips N.V., University of Washington
Inventors:
Jinnan Wang, Huijun Chen, Peter Boernert, Chun Yuan
Abstract: The present invention relates to indoline alkaloid compounds. In particular, indoline alkaloid compounds of the invention have antibacterial activity and/or are capable of resensitizing the susceptibility of methicillin-resistant S. aureus to a ?-lactam antibiotic. The present invention also relates to a method for producing and using the same.
Type:
Grant
Filed:
April 1, 2014
Date of Patent:
August 29, 2017
Assignee:
The Regents of the University of Colorado
Abstract: Lithium metal oxides may be regenerated under ambient conditions from materials recovered from partially or fully depleted lithium-ion batteries. Recovered lithium and metal materials may be reduced to nanoparticles and recombined to produce regenerated lithium metal oxides. The regenerated lithium metal oxides may be used to produce rechargeable lithium ion batteries.
Abstract: This invention provides metal nanoparticles (e.g., aluminum, chromium, iron and magnesium) having an epoxide-based oligomer coating, compositions thereof, method of making the same, and methods of use thereof, including for energy related applications.
Type:
Grant
Filed:
July 7, 2011
Date of Patent:
August 29, 2017
Assignee:
Saint Louis University
Inventors:
Paul Jelliss, Steven Buckner, Stephen W. Chung, Brandon J. Thomas
Abstract: ‘NCDX2’ is a new cultivar of hybrid Deutzia with a compact, low-growing, arching/spreading growth habit with a profusion of showy pink-striped petals.