Patents Assigned to The University
  • Patent number: 9747544
    Abstract: A method and system for wastewater treatment based on dissolved oxygen control by a fuzzy neural network, the method for wastewater treatment comprising the following steps: (1) measuring art inlet water flow rate, an ORP value in an anaerobic tank, a DO value in an aerobic tank, an inlet water COD value, and an actual outlet water COD value; (2) collecting the measured sample data and sending them via a computer to a COD fuzzy neural network predictive model, so as to establish an outlet water COD predicted value, (3) comparing the outlet COD predicted value with the outlet water COD set value, so as to obtain an error and an error change rate, and using them as two input variables to adjust a suitable dissolved oxygen concentration. Accordingly, the on-line prediction and real-time control of dissolved oxygen wastewater treatment are achieved.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: August 29, 2017
    Assignee: SOUTH CHINA UNIVERSITY OF TECHNOLOGY
    Inventors: Jinquan Wan, Mingzhi Huang, Yongwen Ma, Yan Wang
  • Patent number: 9743675
    Abstract: Antimicrobial compositions comprising a terpenoid in combination with an antimicrobial agent are provided. In addition, uses of such compositions in various applications involving preventing, combating or treating microbial infections, or preventing microbial growth or establishment are provided.
    Type: Grant
    Filed: September 10, 2010
    Date of Patent: August 29, 2017
    Assignee: UNIVERSITY OF SURREY
    Inventors: Franciscus Antonius Anna Maria De Leij, Mina Kalantarzadeh, Dulcie Mulholland, Tony Hutchings
  • Patent number: 9745596
    Abstract: The invention provides a wheat cell, part, tissue culture or whole plant comprising at least one disrupted KRP gene of the present invention. The present invention also provides methods of increasing weight, size, and/or number of one or more organs, and/or yield of a wheat plant by utilizing the disrupted KRP genes of the present invention. Furthermore, methods of breeding wheat plants to produce new wheat plants having increased weight, size, and/or number of one or more organs, and/or yield are provided. The present invention provides isolated Kinase Inhibitor Protein (KIP) Related Protein (KRP) polynucleotide sequences and isolated KRP polypeptide sequences and methods of their use.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: August 29, 2017
    Assignees: Targeted Growth, Inc., The Regents of the University of California
    Inventors: Jean Paul Olivier, Tom Todaro, Jorge Dubcovsky, Wenjun Zhang
  • Patent number: 9746468
    Abstract: Methods, systems, devices and materials are disclosed for implementing a bioaffinity sensor having a self-assembled monolayer interface for detection of a target molecule. In one aspect, a sensor device for detecting a target molecule includes a surface capable of attaching a thiol and a molecular monolayer formed on the surface that includes a molecular capture probe having a thiol region, a linear alkanethiol molecule having one thiol region, and a linear alkanedithiol molecule having two thiol regions, in which the molecular capture probe includes a region for receiving a target substance having a complimentary region that couples with the region of the molecular capture probe to generate a detectable signal.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: August 29, 2017
    Assignee: The Regents of the University of California
    Inventors: Joseph Wang, Susana Campuzano-Ruiz
  • Patent number: 9744189
    Abstract: Lithium is regarded as the gold standard comparator and benchmark treatment for mania. One of the problems associated with Lithium is its narrow therapeutic window. Recent attempts to find new drugs with similar therapeutic activities have yielded new chemical entities. However, these potential new drugs have yet to match the many bioactivities attributable to lithium's efficacy for the treatment of neuropsychiatric diseases. Consequently, an intense effort for re-engineering lithium therapeutics using cocrystallization is currently underway. The evaluation of pharmacokinetics of previously unexplored lithium salts with organic anions (lithium salicylate and lithium lactate) has found that these lithium salts exhibit profoundly different pharmacokinetics compared to the more common FDA approved salt, lithium carbonate, in rats.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: August 29, 2017
    Assignee: University of South Florida
    Inventors: Adam J. Smith, R. Douglas Shytle
  • Patent number: 9743961
    Abstract: A fusion device includes a screw having a head and a shaft. A hollow bone dowel is disposed about the shaft of the screw. The bone dowel is formed from a bone-like, biocompatible, or allograft material.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: August 29, 2017
    Assignee: The University of Toledo
    Inventors: Vijay K. Goel, Anand K. Agarwal, David Dick
  • Patent number: 9744188
    Abstract: Disclosed herein are methods of inducing neuronal outgrowth of a neuron. The methods comprise contacting the neuron with an agent that binds receptor protein tyrosine phosphatase ? (RPTP?), to thereby induce neuronal outgrowth of the neuron. The agent may induces clustering of RPTP? and/or inhibit binding of chondroitin sulfate proteoglycan (CSPG) to RPTP?. Examples of suitable agents are heparan sulfate proteoglycan, heparan sulfate, heparan sulfate oligosaccharides, or heparin oligosaccharides. Additional agents are also disclosed. The neuron can be a CNS neuron or peripheral neuron. Also disclosed herein are methods of treating neuronal injury in a subject comprising, administering to the subject an agent that binds RPTP?. Administration may be to a site of neuronal injury, to thereby induce neuronal outgrowth at the site of neuronal injury.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: August 29, 2017
    Assignees: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
    Inventors: John G. Flanagan, Yingjie Shen, Edith Yvonne Jones, Alexandru Radu Aricescu, Charlotte Hannah Coles
  • Patent number: 9744194
    Abstract: The invention relates generally to methods of treating spasticity, rigidity, or muscular hyperactivity conditions by introducing a portion of an expanded population of neural stem cells into an area of a recipient spinal cord.
    Type: Grant
    Filed: November 30, 2015
    Date of Patent: August 29, 2017
    Assignees: Neuralstem, Inc., The Regents of the University of California
    Inventors: Karl K. Johe, Thomas G. Hazel, Martin Marsala, Osamu Kakinohana
  • Patent number: 9746480
    Abstract: Provided herein are methods for determining the presence of cancer (malignant versus benign), monitoring the progression of cancer, monitoring cancer relapse, monitoring the response to cancer therapy, or cancer staging in a subject, by evaluating CD33+/HLA-DRlow, CD14+/HLA-DRlow, CD66b+/HLA-DRlow or, CD11b+/HLA-DRlow MDSC for activation of a transcription factor. Transcription factors include, but are not limited to, STAT3, pSTAT3, HIF1?, or C/EBP?. The MDSC phenotype can be CD33+HLA-DRlowHIF1?+/STAT3+, CD14+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD66b+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD33+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, CD11b+HLA-DRlowHIF1?+/STAT3+/pSTAT3+/C/EBPb+, or CD11b+HLA-DRlowC/EBP?+. Also provided herein are methods for inducing human MDSC from healthy donor peripheral blood mononuclear cells (PBMC) by co-culturing PBMC with human solid tumor cell lines and subsequently measuring their suppressive ability.
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: August 29, 2017
    Assignee: University of Southern California
    Inventors: Alan L. Epstein, Melissa G. Lechner
  • Patent number: 9747687
    Abstract: A system and method for automated polyp detection in optical colonoscopy images is provided. In one embodiment, the system and method for polyp detection is based on an observation that image appearance around polyp boundaries differs from that of other boundaries in colonoscopy images. To reduce vulnerability against misleading objects, the image processing method localizes polyps by detecting polyp boundaries, while filtering out irrelevant boundaries, with a generative-discriminative model. To filter out irrelevant boundaries, a boundary removal mechanism is provided that captures changes in image appearance across polyp boundaries. Thus, in this embodiment the boundary removal mechanism is minimally affected by texture visibility limitations. In addition, a vote accumulation scheme is applied that enables polyp localization from fragmented edge segmentation maps without identification of whole polyp boundaries.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: August 29, 2017
    Assignees: Arizona Board of Regents on Behalf of Arizona State University, Mayo Foundation for Medical Education and Research
    Inventors: Nima Tajbakhsh, Suryakanth R. Gurudu, Jianming Liang
  • Patent number: 9749126
    Abstract: Provided is a data transmitter including a signal interval determination unit configured to receive a data input signal corresponding to data to be transmitted, determine time intervals between a synchronization signal and a plurality of data signals according to the data input signal, and output interval signals corresponding to the intervals; a trigger generation unit configured to trigger according to an output signal from the signal interval determination unit; and a signal generation unit configured to receive the trigger to generate the synchronization signal and the data signals.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: August 29, 2017
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Tae Wook Kim, Taek Hyun Jung, Geun-Haeng Lee
  • Patent number: 9749620
    Abstract: Provided is a disparity correcting device which rapidly corrects disparity information generated on the basis of a left image and disparity information generated on the basis of a right image through a simple configuration, and a method thereof, in stereo vision which generates a 3-dimensional image using a left image and a right image captured from left and right cameras.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: August 29, 2017
    Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY—ACADEMIC COOPERATION FOUNDATION
    Inventors: Byung In Moon, Kyeong Ryeol Bae
  • Patent number: 9745255
    Abstract: The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: August 29, 2017
    Assignees: The Regents of the University of California, Fondazione Istituto Italiano di Technologia, Universita Degli Studi di Urbino “Carlo Bo”, Universita Degli Studi di Parma
    Inventors: Daniele Piomelli, Guillermo Moreno-Sanz, Tiziano Bandiera, Marco Mor, Giorgio Tarzia
  • Patent number: 9748853
    Abstract: One example embodiment is a method executed by a microcontroller with a Pulse Width Modulation (PWM) circuit to control a semi-dual-active-bridge (SDAB) converter that includes a first side bridge circuit, a second side bridge circuit and a transformer. The microcontroller determines a current operation mode and a target operation mode of the SDAB converter. The microcontroller determines an optimal ratio and calculates changes of each gating signal that are applied to the first side bridge circuit and the second side bridge circuit respectively.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: August 29, 2017
    Assignee: Macau University of Science and Technology
    Inventor: Xiaodong Li
  • Patent number: 9745965
    Abstract: Printed active origami combines printed electronics with nanomaterial coated polymer based actuators to create active printed structures. The fabrication processes include the step of applying carbon nanomaterial coatings to polymeric films. Products produced by the processes include actuating materials, such as solid state actuators that can be used as active element(s) in a printable active origami robot.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 29, 2017
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Mike O'Connell, Brett Yost, Takayuki Nosaka, Chegwei Wang
  • Patent number: 9746536
    Abstract: A magnetic resonance system (10), and corresponding method, image a subject using a conversion-free interleaved black and bright blood imaging (cfIBBI) sequence. A MR scanner (12) is controlled to perform a plurality of repetitions of a black blood imaging sequence (52). The black blood imaging sequence (52) includes a tissue nulling sub-sequence followed by a black blood acquisition sub-sequence (56) performed a time interval (TI) after the tissue nulling sub-sequence. The MR scanner (12) is further controlled to, between successive repetitions of the black blood imaging sequence (52), perform a bright blood imaging sequence (54) including the tissue nulling sub-sequence followed by a bright blood acquisition sub-sequence (58) performed the time interval (TI) after the tissue nulling sub-sequence. The time intervals (TI) of the black blood imaging sequence (52) and the bright blood imaging sequence (54) are of the same duration.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: August 29, 2017
    Assignees: Koninklijke Philips N.V., University of Washington
    Inventors: Jinnan Wang, Huijun Chen, Peter Boernert, Chun Yuan
  • Patent number: 9745266
    Abstract: The present invention relates to indoline alkaloid compounds. In particular, indoline alkaloid compounds of the invention have antibacterial activity and/or are capable of resensitizing the susceptibility of methicillin-resistant S. aureus to a ?-lactam antibiotic. The present invention also relates to a method for producing and using the same.
    Type: Grant
    Filed: April 1, 2014
    Date of Patent: August 29, 2017
    Assignee: The Regents of the University of Colorado
    Inventors: Xiang Wang, Jessica Podoll, Le Chang
  • Patent number: 9748616
    Abstract: Lithium metal oxides may be regenerated under ambient conditions from materials recovered from partially or fully depleted lithium-ion batteries. Recovered lithium and metal materials may be reduced to nanoparticles and recombined to produce regenerated lithium metal oxides. The regenerated lithium metal oxides may be used to produce rechargeable lithium ion batteries.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: August 29, 2017
    Assignee: University of Calcutta
    Inventor: Nilanjan Deb
  • Patent number: 9745190
    Abstract: This invention provides metal nanoparticles (e.g., aluminum, chromium, iron and magnesium) having an epoxide-based oligomer coating, compositions thereof, method of making the same, and methods of use thereof, including for energy related applications.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: August 29, 2017
    Assignee: Saint Louis University
    Inventors: Paul Jelliss, Steven Buckner, Stephen W. Chung, Brandon J. Thomas
  • Patent number: PP28347
    Abstract: ‘NCDX2’ is a new cultivar of hybrid Deutzia with a compact, low-growing, arching/spreading growth habit with a profusion of showy pink-striped petals.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: August 29, 2017
    Assignee: North Carolina State University
    Inventor: Thomas G. Ranney