Patents Assigned to Tianjin University
  • Patent number: 9834567
    Abstract: A novel crystalline form is defined by diffraction angle 2?° of X-ray powder diffraction pattern and characteristic peak of differential scanning calorimetry (DSC). The novel crystalline form of Cefamandole Nafate is prepared as follows: adding Cefamandole Nafate in solid state to an organic solvent to form a suspension with a concentration of 0.04˜0.3 g/ml, stirring the suspension at 40˜50° C. for a period of time, and then cooling to 5˜15° C. at certain cooling rate, continuing to stir for a period of time, then suction filtrating the obtained suspension, the resulting filer cake is Cefamandole Nafate as wet product, which is dried to constant weight to provide the novel crystalline form of Cefamandole Nafate as final product.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: December 5, 2017
    Assignees: TIANJIN UNIVERSITY, HAINAN LINGKANG PHARMACEUTICAL CO., LTD
    Inventors: Hongxun Hao, Linggang Tao, Fang He, Baohong Hou, Jingkang Wang, Jun Lv, Qiuxiang Yin, Yongli Wang, Junbo Gong, Chuang Xie, Ying Bao
  • Patent number: 9815848
    Abstract: This invention provides a new preparation method of Clopidogrel Hydrogen Sulfate spherical crystal form I, using single 2-butanol as solvent, controlling the concentration, addition way and addition speed of sulfuric acid used to salify to shorten the process time, thus separating out Clopidogrel Hydrogen Sulfate from solution system stably with spherality. And the Clopidogrel Hydrogen Sulfate obtained complies with the requirements of the follow-up process on residual solvent, bulk density and mobility.
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: November 14, 2017
    Assignees: TIANJIN UNIVERSITY, SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD
    Inventors: Junbo Gong, Qi Wang, Qiuxiang Yin, Jingkang Wang, Xiaopeng Song, Baohong Hou, Liting Liao, Duanming Tan, Ziyuan Di
  • Publication number: 20170321132
    Abstract: The present invention provides a catalytic cracking fractionation and absorption-stabilization system, and energy saving method thereof; the present invention is to arrange a waste heat refrigerator of the main fractionating tower, a waste heat refrigerator of rich gas and a waste heat refrigerator of stabilizer in a catalytic cracking fractionation and absorption-stabilization system so as to utilize low temperature waste heat at the top of a main fractionating tower, rich gas, stable gasoline, intermediate heat exchange flow of an absorber of the system as a refrigerator driving heat source; in order to cool naphtha and circulating gasoline to a low temperature lower than 40° C., control low temperature operations of the absorber and reduce the heat load of a desorber and a stabilizer, and the heat extracted by the refrigerators is cooled by cooling water with a higher temperature so as to reduce the consumption of the cooling water.
    Type: Application
    Filed: December 12, 2014
    Publication date: November 9, 2017
    Applicants: Tianjin University, Pei-Yang National Distillation Technology Corporation Limited
    Inventors: Hong SUI, Zhen HAN, Xingang LI, Jingyi LI
  • Patent number: 9789473
    Abstract: A process for the production of organic chemicals and fuels from lignin in the presence of a molybdenum or tungsten based catalyst, comprising mixing the lignin with the catalyst and a solvent in a sealed reactor, introducing an inert gas or hydrogen to the reactor to replace oxygen therein, and heating the sealed reactor to perform a depolymerization reaction at a reaction temperature of above 200° C. to obtain liquid products, which include aromatic compounds, esters, alcohols, monophenols and benzyl alcohols.
    Type: Grant
    Filed: July 6, 2015
    Date of Patent: October 17, 2017
    Assignee: TIANJIN UNIVERSITY
    Inventors: Yongdan Li, Rui Ma, Xiaolei Ma, Wenyue Hao
  • Patent number: 9769407
    Abstract: The present invention relates to technical field of analog integrated circuit design. TDI function is better realized by CMOS image sensor and it improves scanning frequency of the CMOS-TDI image sensor and extends application range of TDI technique. To this end, the present invention proposes a technical solution of a current accumulative pixel structure for CMOS-TDI image sensor which comprises a photodiode, four MOS transistors M1, M2, M3, M4, four switches S1, S2, S3, S4, and two capacitors C1, C2; the connection relationship thereof is denoted below: the anode of the photodiode D1 is connected to a ground wire, while the cathode thereof is connected to an input end; the drain and gate of the transistor M1 are both connected with the input end, while the source thereof is connected with a power source VDD. The current invention mainly finds its application in analog integration circuit design.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: September 19, 2017
    Assignee: Tianjin University
    Inventors: Kaiming Nie, Suying Yao, Jiangtao Xu, Zaifeng Shi, Zhiyuan Gao, Jing Gao
  • Publication number: 20170226730
    Abstract: A foldable tubular construct/element with one rigid degree of freedom is of a tubular construction formed by a number of single layered annular units which are connected in sequence; each single layered annular unit is of a prism having N ridge lines; two adjacent prisms each having N sides are connected to each other by sharing a polygon with N sides formed on an intersection plane; each prism with N ridge lines is composed of N rigid planar quadrilateral facets; two adjacent single layered annular units comprise N spherical mechanisms formed by the intersections of only four planar quadrilateral facets at each apex; the polygon having N sides formed in the intersection plane of the two adjacent single layered annular units is a planar polygon with an arbitrary number of sides greater than for a triangle; the ridge lines of each prism having N ridge lines are parallel to each other; the connecting ridge lines of the tubular element are coplanar; when the polygon having N sides formed in the intersection plan
    Type: Application
    Filed: November 6, 2014
    Publication date: August 10, 2017
    Applicant: Tianjin University
    Inventors: Yan CHEN, Sicong LIU, Jianmin LI, Kunfeng WANG, Weilin LV, Kaori SHIGETOMI
  • Publication number: 20170197937
    Abstract: A novel crystalline form is defined by using diffraction angle 2?° of X-ray powder diffraction pattern and characteristic peaks of differential scanning calorimetry (DSC). Pantoprazole Sodium solid is added to an alcohol solvent to form a suspension with a concentration of 0.05˜0.2 g/mL, and then an antioxidant is added to the suspension, completely dissolving the solid at a temperature of 15˜35° C., and a solventing-out agent is dropwise added to the solution under the application of ultrasonic wave, wherein the amount of the solventing-out agent is 3˜10 times (in volume) of the alcohol solvent; followed by cooling the solution down to 0˜5° C., continuing to stir for 1˜3 h, and suction filtrating obtained solid-liquid suspension to provide a novel crystalline form of Pantoprazole Sodium crystal after drying the product to constant weight.
    Type: Application
    Filed: November 20, 2015
    Publication date: July 13, 2017
    Applicants: TIANJIN UNIVERSITY, HAINAN LINGKANG PHARMACEUTICAL CO., LTD
    Inventors: Hongxun HAO, Linggang TAO, Shen JIANG, Yongli WANG, Jingkang WANG, Jun LV, Qiuxiang YIN, Baohong HOU, Zhao XU, Chuang XIE, Zhao WANG
  • Publication number: 20170180666
    Abstract: The present invention relates to technical field of analog integrated circuit design. TDI function is better realized by CMOS image sensor and it improves scanning frequency of the CMOS-TDI image sensor and extends application range of TDI technique. To this end, the present invention proposes a technical solution of a current accumulative pixel structure for CMOS-TDI image sensor which comprises a photodiode, four MOS transistors M1, M2, M3, M4, four switches S1, S2, S3, S4, and two capacitors C1, C2; the connection relationship thereof is denoted below: the anode of the photodiode D1 is connected to a ground wire, while the cathode thereof is connected to an input end; the drain and gate of the transistor M1 are both connected with the input end, while the source thereof is connected with a power source VDD. The current invention mainly finds its application in analog integration circuit design.
    Type: Application
    Filed: December 12, 2014
    Publication date: June 22, 2017
    Applicant: TIANJIN UNIVERSITY
    Inventors: Kaiming NIE, Suying YAO, Jiangtao XU, Zaifeng SHI, Zhiyuan GAO, Jing GAO
  • Publication number: 20170180667
    Abstract: The present invention relates to technical field of analog integrated circuit design. TDI function is better realized by CMOS image sensor and it improves scanning frequency of the CMOS-TDI image sensor and extends application range of TDI technique. To this end, the present invention proposes a technical solution of high scanning frequency CMOS-TDI image sensor. The pixels include a photodiode, an operational amplifier, integration capacitors C1 and C2 of the same capacitance, an offset voltage removing capacitor C3, and plural switches S1-S10. The anode of the photodiode is connected to a zero voltage ground wire, while the cathode thereof is connected to one end of the switch S9. The other end of the switch S9 is connected to a reference voltage Vref. The above pixels are cascaded and an output end of the last pixel is connected to a column-parallel ADC through a readout switch Read. The invention mainly applies to analog integration circuit design.
    Type: Application
    Filed: December 12, 2014
    Publication date: June 22, 2017
    Applicant: Tianjin University
    Inventors: Kaiming NIE, Suying YAO, Jiangtao XU, Zhiyuan GAO, Zaifeng SHI, Jing GAO
  • Publication number: 20170158711
    Abstract: It discloses a new industrial crystallization method of Cefuroxime Sodium, wherein supercritical fluid extraction technology and traditional crystalline technology are combined to realize the recrystallization of Cefuroxime Sodium. Processes such as extraction, adsorption, crystallization and drying are carried out with a supercritical fluid, a solvent, an extraction cell and a crystallization tank to realize the recrystallization of Cefuroxime Sodium under a specific pressure at a specific temperature.
    Type: Application
    Filed: November 27, 2015
    Publication date: June 8, 2017
    Applicants: HAINAN LINGKANG PHARMACEUTICAL CO., LTD., TIANJIN UNIVERSITY
    Inventors: Linggang TAO, Hongxun HAO, Jingkang WANG
  • Publication number: 20170157574
    Abstract: The present invention relates to a polyetherimide composite nanofiltration membrane and a preparation method thereof, the method comprises the following steps: (1) dissolving polyetherimide and an additive into an organic solvent, stirring and keeping aside for deaeration to prepare a casting solution, blade coating of the casting solution onto a smooth surface of a nonwoven fabric, and placing under an air atmosphere and then putting into deionized water to obtain a support membrane 1, wherein the surface of the nonwoven fabric coated with the casting solution is referred to as surface A; (2) immersing the surface A of the support membrane 1 into an aqueous solution of m-phenylenediamine, taking out and drying in the air, then immersing the surface A into a solution of 1,2,4,5-benzene tetracarbonyl chloride in n-hexane or cyclohexane, and taking out and drying in the air to obtain a support membrane 2; and (3) immersing the surface A of the support membrane 2 into an aqueous solution of EDC.
    Type: Application
    Filed: December 13, 2014
    Publication date: June 8, 2017
    Applicant: Tianjin University
    Inventors: Wei LI, Jinli ZHANG, Yuyan HAI, Qian JIANG, Ayang ZHOU
  • Patent number: 9663841
    Abstract: The present invention published a large walled field conditions P92 long pipeline local heat treatment processes. Firstly, according to the specific conditions for the on-site grade heat-resistant steel (P92 pipe), combining of the finite element method and test, the Heated Band (HB) width and Gradient Control Band (GCB) was calculated. The pipe was then locally heated using the flexible ceramic resistive heater. When the temperature reaches 80-100° C., the pipe was heated to constant temperature at 80-100° C. for 2 h. The pipe was heated to 300° C. at the rate of 150° C./h. When the temperature reaches 300° C., rising the temperature to 765° C. at the rate of 80° C./h. Holding time is calculated by the wall thickness (5 min/mm, no less than 4 h). Lowering the temperature to 300° C. at the rate of 100° C./h and then natural cooling to room temperature, finally removing the heating device. Finally, the local heat treatment process can be obtained.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: May 30, 2017
    Assignee: Tianjin University
    Inventor: Yingjin Yuan
  • Publication number: 20170145966
    Abstract: The present invention discloses a novel engine controlled by combustion reaction path, which cylinders comprise working cylinders and reforming cylinders. According to the operational condition of engine, the engine is used for compressing, heating and reforming the fuel injected from the reforming cylinder injector; by controlling the reaction boundary conditions between fuel and air, the reforming cylinder can exhaust partial intermediate products or oxidation products of the different oxidation stages; the products are then mixes with the inlet air in the pre-mixing chamber and then is introduced into the working cylinder.
    Type: Application
    Filed: September 18, 2016
    Publication date: May 25, 2017
    Applicant: Tianjin University
    Inventors: Mingfa YAO, Yang WANG, Guorui JIA, Hu WANG, Lixia WEI
  • Patent number: 9658261
    Abstract: A harmonic-characteristics based current pattern matching method for the non-intrusive power load monitoring and disaggregation is provided in this present invention, on the basis of establishing the load signature database, which comprises electrical appliance registration and load state word space initialization, data acquisition and data preprocessing, feasible state word space search based on table looking-up, the optimal matching of current pattern, and display and output of the monitoring and disaggregation results. The method improves the accuracy of disaggregation, and can achieves exact identification of operating states of appliances, and also can reduce the cost.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: May 23, 2017
    Assignee: Tianjin University
    Inventors: Yixin Yu, Bo Liu, Bing Wang
  • Patent number: 9658055
    Abstract: The present invention relates to an accuracy traceability method based on precision coordinates control network for workshop Measurement Positioning System, which includes the steps: setting a plurality of SMR (Spherically Mounted Retroreflector) nests and stations in the measurement space; forming a global control point by using SMR; measuring all the 3-d coordinates of global control points in all the laser tracker stations; using the range value measured by the laser tracker as constraints to calculate the 3-d coordinates of global control points by using the dynamic weighting method; arranging a plurality of transmitters and calibrating the transmitters in combination with precision coordinate control network; measuring all global control points and measured points simultaneously by using wMPS, and using the 3-d coordinates of global control points as the constraints for adjustment calculation to obtain the 3-d coordinates of the measured points.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: May 23, 2017
    Assignee: Tianjin University
    Inventors: Jigui Zhu, Jiarui Lin, Yongjie Ren, Linghui Yang, Yu Ren
  • Publication number: 20170129922
    Abstract: Affinity peptide ligands of mouse polyomavirus capsomers and a designed screening method thereof. The affinity peptide ligands can be used for separation and purification of the capsomers.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 11, 2017
    Applicant: TIANJIN UNIVERSITY
    Inventors: Lin ZHANG, Xiaoyan DONG, Yanying LI, Xiaodan LIU, Yan SUN
  • Publication number: 20170126992
    Abstract: The present invention relates to a CMOS image sensor. The present invention provides a digital pixel sensor capable of maintaining consistency between two reference voltage changing rates. To this end, the invention proposes a technical solution in which a digital pixel exposure method by using multiple ramp voltage as reference voltage is provided.
    Type: Application
    Filed: December 12, 2014
    Publication date: May 4, 2017
    Applicant: Tianjin University
    Inventors: Suying YAO, Zhiyuan GAO, Jiangtao XU, Zaifeng SHI, Jing GAO
  • Patent number: 9637502
    Abstract: A novel crystalline form of Cefathiamidine compound and its preparation method, characterizing in its X-ray powder diffraction pattern and differential scanning calorimetry thermogram. Dissolving Cefathiamidine compound with a purity of 98% or higher in a solvent at a temperature of 30˜45° C. to form a solution, whose concentration is controlled within 0.05˜0.2 g/mL, and then adding a solventing-out agent to the solution, wherein the amount of the solventing-out agent is 3˜5 times (in volume) of that of the solvent; followed by cooling the solution down to 0˜10° C. at a rate of 0.2˜1° C./min; continuing to stir for 1˜3 hours, and separating the obtained solid-liquid suspension to provide a novel crystalline form of Cefathiamidine compound after drying.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: May 2, 2017
    Assignees: TIANJIN UNIVERSITY, HAINAN LINGKANG PHARMACEUTICAL CO., LTD
    Inventors: Hongxun Hao, Linggang Tao, Zhihong Sun, Baohong Hou, Jun Lv, Qiuxiang Yin, Yongli Wang, Junbo Gong, Chuang Xie, Ying Bao
  • Patent number: 9636627
    Abstract: The present invention discloses a method and a device for recovering ethylene during the process for producing vinyl acetate, wherein a double solvent absorption method composed of an absorbent solution and deionized water is adopted.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: May 2, 2017
    Assignee: Tianjin University
    Inventor: Yingjin Yuan
  • Publication number: 20170084904
    Abstract: A cylindrical single-piece lithium-ion battery of 400 Ah includes: a cylindrical battery enclosure (1), a battery mandrel (3), a plurality of tabs (4), a wiring terminal (6), a positive and negative electrode cover (11); a positive electrode sheet, said battery positive electrode is composed of LiFePO4, conductive carbon-black, graphite, adhesive such as PVDF, and solvent such as NMP; a negative electrode sheet, the battery negative electrode is composed of lithium titanate, conductive carbon-black, graphite, adhesive such as PVDF, and solvent such as NMP. The cylindrical lithium-ion battery made by the invention has a capacity of 400 Ah which is the one reportedly having the largest capacity in the world presently.
    Type: Application
    Filed: September 28, 2016
    Publication date: March 23, 2017
    Applicant: Tianjin University
    Inventors: Zhiyuan TANG, Lei Sun, Qi Wang, Guowei Ling