Patents Assigned to Tokai University Educational Systems
  • Patent number: 7205519
    Abstract: A confocal microscope apparatus has a confocal scanner for scanning a sample with shifting a focal position of a light beam in a direction perpendicular to an optical axis, a moving mechanism for moving the focal position of the light beam in an optical axis direction, a camera for picking up an image of the sample with the light beam, and a movement control unit for controlling the moving mechanism to move the focal position of the light beam by a predetermined distance in the optical axis direction for every vertical synchronizing signal of the camera in synchronization with the vertical synchronizing signal. A high-speed three-dimensional image can be displayed in such that while measuring the sample, two or more slice images in such an arrangement on a common screen that their positions relative to the sample enables to be grasped.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: April 17, 2007
    Assignees: Tokai University Educational System, Yokogawa Electric Corporation
    Inventors: Hideyuki Ishida, Takeo Tanaami
  • Publication number: 20070073196
    Abstract: An apparatus generates a cutaneous sense stimulus to call a subject attention to a change in posture based on posture change information (the amount of change in the barycenter, a changing direction of the same, and the like) from a device for detecting a change in posture of the subject. The apparatus has stimulus generating means (a plurality of vibrators) for generating a cutaneous sense stimulus, and stimulus control means for driving the stimulus generating means based on the posture change information. The control means comprises means for selecting a plurality of vibrators arranged substantially parallel with the changing direction based on the changing direction of the barycenter, and sequentially driving the selected vibrators, for example, in a direction substantially opposite to the direction in which the barycenter changes. The control means also drives the vibrators to generate the tactile sense stimulus of a magnitude corresponding to a changing amount of the barycenter.
    Type: Application
    Filed: May 21, 2004
    Publication date: March 29, 2007
    Applicants: Hokkaido Technology Licensing Office Co., Ltd., Tokai University Educational System, Kyowa Electronic Instruments Co., Ltd.
    Inventors: Toshiaki Tanaka, Takashi Izumi, Takeshi Tsuruga, Akinori Omura
  • Patent number: 7169407
    Abstract: The present invention provides agents that decrease carbonyl stress comprising biguanides, such as metoformin. Through oral administration and such, the carbonyl stress-decreasing agents of the present invention are useful as drugs directly acting against carbonyl stress in vivo.
    Type: Grant
    Filed: October 6, 2000
    Date of Patent: January 30, 2007
    Assignees: Kiyoshi Kurokawa, Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 7132692
    Abstract: An object of the present invention is to allow the three primary colors of light (red, green, blue) to be emitted, and particularly to allow blue light to be emitted clearly and in a stable manner at a low voltage. An amorphous SiOx film 2 consisting of a mixture of silicon atoms and oxygen atoms is formed on a semiconductor substrate 1. The result is heat treated in an inert gas to form the silicon atoms into nanosilicon 4a of about 3.0 nm or less. The result is subjected to hydrofluoric acid aqueous solution treatment 5 and thermal oxidation treatment 6. Any of the three primary colors of light, particularly blue, can be emitted at a low operating voltage 7 at room temperature.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: November 7, 2006
    Assignee: Tokai University Educational System
    Inventors: Tomio Izumi, Keisuke Sato, Mitsuo Iwase
  • Patent number: 7072732
    Abstract: A computer solves an item-based one-dimensional sub-optimization problem independently of the other items. For the item-based solution found, the computer determines whether machine interference between the items is eliminated and whether a work-in-process inventory is sufficient. If machine interference is not eliminated or the work-in-process inventory is not insufficient, then the computer updates a corresponding Lagrange multiplier and reexecutes the solving of the problem.
    Type: Grant
    Filed: December 27, 2002
    Date of Patent: July 4, 2006
    Assignees: Tokai University Educational System, Information and Mathematical Science Laboratory
    Inventors: Kenji Muramatsu, Aditya Warman, Minoru Kobayashi, Takuya Yamaguchi
  • Patent number: 7029906
    Abstract: Carbonyl stress-ameliorating agents have been provided, which contain an enzyme having a glyoxalase I activity and a carbonyl compound-reducing agent as the active ingredients. The carbonyl stress-ameliorating agents of the present invention rapidly eliminate carbonyl compounds, and thus ameliorate carbonyl induced stress conditions.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: April 18, 2006
    Assignees: Tokai University Education System
    Inventor: Toshio Miyata
  • Patent number: 7026126
    Abstract: The present invention provides a method for evaluating renal functions by measuring megsin protein in a biological specimen. Moreover, the present invention provides immunological assay reagents, as well as kits useful for the measurement of megsin protein in the biological specimen.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: April 11, 2006
    Assignees: Tokai University Educational System, Fuso Pharmaceutical Industries, Ltd.
    Inventor: Toshio Miyata
  • Patent number: 6986412
    Abstract: A tuned cradle type damping deice which can be tuned with low-order (e.g., 1 Hz or lower) vibration, and exhibits higher performance for maintenance and inspection with a simple constitution than a conventional one. This tuned cradle type damping device comprises: a support having a circular-arc support surface which is at least a part of a circle; two swings positioned on both outsides of a center axis extending direction of the circular-arc support surface of the support; and two rollers which are rotatably supported on the circular-arc support surface to be rolled thereon and moved around the center axis thereof, and both ends of which are rotatably connected to the two swings to support the two swings.
    Type: Grant
    Filed: March 9, 2004
    Date of Patent: January 17, 2006
    Assignees: Tokai University Educational Systems, Nippon Comsys Corporation
    Inventors: Yoji Shimazaki, Morio Obata, Wataru Morijiri
  • Patent number: 6987906
    Abstract: An optical connection device according to the invention is an optical connection device for optically coupling light propagated through an optical waveguide to an optical element arranged outside the optical waveguide and with the following configuration. Part of the optical waveguide is removed so as to be shaped like a groove. The optical waveguide and the optical element are arranged so that an optical axis of the optical waveguide intersects an optical axis of the optical element at a specified angle inside the groove. An optical unit is arranged at a position of intersection of the optical axes for turning light by reflection from one optical axis along the other optical axis.
    Type: Grant
    Filed: August 27, 2003
    Date of Patent: January 17, 2006
    Assignees: Nippon Sheet Glass Co., Ltd., Tokai University Educational System
    Inventors: Kenichi Nakama, Yukinari Sekiguchi, Osamu Mikami, Yoshikazu Murata, Kentarou Miyazato
  • Patent number: 6974309
    Abstract: A Straight blade type turbine has at least one two-dimensional blade positioned in parallel with and around a central axis of the turbine. The two-dimensional blade has a cross section with a blade chord turned around a center of the two-dimensional blade by an angle of 3° to ?2° relative to a line perpendicular to another imaginary line connecting the central axis with the center of the two-dimensional blade. A distance between a fore end and the center of the cross section is 15 to 40 percent of a chord length of the blade. NC/R, which is calculated by a radius R extending from the axis to the center of two-dimensional blade, the chord length C, and the number N of the two-dimensional blades, is between 0.5 and 2.2. A maximum thickness of the two-dimensional blade is between 20 and 25 percent of the chord length.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: December 13, 2005
    Assignee: Tokai University Educational System
    Inventor: Kazuichi Seki
  • Patent number: 6919326
    Abstract: Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be eliminated by pre-contacting with the trapping agent. Further, it is possible to eliminate carbonyl compounds transferred from the blood to the peritoneal cavity of the patient during peritoneal dialysis treatment, by adding the trapping agent to the peritoneal dialysate or by circulating the fluid through a carbonyl compound-trapping cartridge. Intraperitoneal protein modification by carbonyl compounds is inhibited by the present invention, thereby sufficiently reducing peritoneal disorders associated with peritoneal dialysis treatment.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: July 19, 2005
    Assignees: Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 6913435
    Abstract: In an integrated vane 1 for use in wind or water, main blades 3 arranged around an axial shaft 2 of the vane and support blades 4 for joining the main blades to the axial shaft are integrally formed with light and high strength fiber material such as glass fibers and carbon fibers. The main blade is symmetrical or asymmetrical in its cross sectional view and the support blade is symmetrical in its cross sectional view. The upper support blade may be asymmetrical in its cross sectional view and the lower support blade may have an up-and-down reversed shape of that of the upper support blade. A mountain-shaped portion may be formed at the ends of the main blade for reducing noise. The strength of crossing portions between the main and support blade of the vertical axis vane for use in wind or water is thus improved.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: July 5, 2005
    Assignee: Tokai University Educational System
    Inventor: Kazuichi Seki
  • Patent number: 6899678
    Abstract: The present invention aims to provide a puncture difficulty evaluating device which can readily evaluate the difficulty of puncture in a measuring point. To this end, a puncture difficulty device receives the ultrasound backscattered at the measurement point, determines an integral of the power of the ultrasound over a predetermined angle range, and generates a parameter indicating the difficulty of puncture in the measurement point based on the determined integral.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: May 31, 2005
    Assignees: Tokai University Educational System, Medico's Hirata Inc.
    Inventors: Takaki Shimura, Yasuharu Nimura, Wataru Yoshioka
  • Patent number: 6864594
    Abstract: In a fluid power generator system using operative fluid energy, a measured tip speed ratio and a reference tip speed ratio are compared with each other. If the measured tip speed ratio is smaller than the reference tip speed ratio, a generator is placed in a no-load state, thereby restoring the number of rotations of the wing axial shaft to the number of rotations corresponding to the reference tip speed ratio. Further, the operation of the generator is controlled on the basis of the tip speed ratio calculated from the flow rate of the fluid, thereby providing a maximum output for each flow rate. In this way, a change in the flow rate and number of rotations can be appropriately dealt with and the maximum output for each flow rate of the operative fluid can be dealt with, thereby increasing a quantity of generated power.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: March 8, 2005
    Assignee: Tokai University Educational System
    Inventor: Kazuichi Seki
  • Patent number: 6831374
    Abstract: A fluid power generator system includes an operating mode in which a continuously variable output corresponding to a wide range of a flow rate is given by selectively combining generators with optimum rated outputs from said plurality of generators according to natural fluid energy and the number of rotations of a wing axial shaft; and control means for controlling the operation of each of the generators on the basis of a tip speed calculated from the flow rate of the operative fluid and the number of rotations of said wing axial shaft, thereby acquiring a maximum output for specific flow rate of the operative fluid. In this configuration, the fluid power generator system using operative fluid energy as a driving source can generate a continuously variable output corresponding to a wide range of the flow rate of the fluid and provides a maximum output for an individual flow rate of the operative fluid, thereby increasing a quantity of generated power (by 40% or more than before).
    Type: Grant
    Filed: June 19, 2003
    Date of Patent: December 14, 2004
    Assignee: Tokai University Educational Systems
    Inventor: Kazuichi Seki
  • Publication number: 20040247386
    Abstract: A screw attachment (10, 10′, 10″) disposed around a fastening piece (17) secured to a main fastening body (25a), the screw attachment sandwiched between a head (17b) of the fastening piece and a securing object (22) so that the screw attachment bears a securing force of the fastening piece to press the securing object. The screw attachment includes a pair of arms (12, 13) made of a shape restoring material. Each arm has a fore end, and the fore ends are joined to each other with an adhesive material that is softened when heated. The arms expands radially such that the screw attachment is released from the head of the fastening piece when heat or force is applied to the arms.
    Type: Application
    Filed: May 24, 2004
    Publication date: December 9, 2004
    Applicants: Union Seimitsu Co., Ltd., Nec Tokin Corporation, Sharp Kabushiki Kaisha, Tokai University Educational System
    Inventors: Kazuo Sugiyama, Tadashi Tashima, Kazunari Yoshida, Yu Kagami, Hideo Takaara, Yoshio Shindoh, Masanobu Tanigawa
  • Publication number: 20040197943
    Abstract: An object of the present invention is to allow the three primary colors of light (red, green, blue) to be emitted, and particularly to allow blue light to be emitted clearly and in a stable manner at a low voltage. An amorphous SiOx film 2 consisting of a mixture of silicon atoms and oxygen atoms is formed on a semiconductor substrate 1. The result is heat treated in an inert gas to form the silicon atoms into nanosilicon 4a of about 3.0 nm or less. The result is subjected to hydrofluoric acid aqueous solution treatment 5 and thermal oxidation treatment 6. Any of the three primary colors of light, particularly blue, can be emitted at a low operating voltage 7 at room temperature.
    Type: Application
    Filed: March 23, 2004
    Publication date: October 7, 2004
    Applicant: Tokai University Educational System
    Inventors: Tomio Izumi, Keisuke Sato, Mitsuo Iwase
  • Publication number: 20040137495
    Abstract: The present invention provides a DNA expressed at high frequency in mesangial cells and a protein (Meg-4) encoded by this DNA. These substances are useful in, for example, identifying mesangial cells and detecting abnormalities in mesangial cells. Moreover, the above protein would be helpful for clarification of the functions of mesangial cells and, in its turn, for clarification of the causes of diseases relating to mesangial cells. This protein is expectedly applicable to the treatment, diagnosis, and such of diseases relating to mesangial cells.
    Type: Application
    Filed: January 13, 2004
    Publication date: July 15, 2004
    Applicants: Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 6680370
    Abstract: The present invention provides a DNA expressed at high frequency in mesangial cells and a protein (Meg-4) encoded by this DNA. These substances are useful in, for example, identifying mesangial cells and detecting abnormalities in mesangial cells. Moreover, the above protein would be helpful for clarification of the functions of mesangial cells and, in its turn, for clarification of the causes of diseases relating to mesangial cells. This protein is expectedly applicable to the treatment, diagnosis, and such of diseases relating to mesangial cells.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: January 20, 2004
    Assignees: Tokai University Educational System
    Inventor: Toshio Miyata
  • Patent number: 6670040
    Abstract: Disclosed is a carbon fiber-reinforced carbon composite body, characterized in that the inner region of the carbon fiber-reinforced carbon composite material is doped with silicon boride.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: December 30, 2003
    Assignee: Tokai University Educational System
    Inventors: Junichi Matsushita, Samon Tanaka