Abstract: Provided is a method for quantifying vitamin D, with the vitamin D contained in a biological sample being derivatized with a derivatization reagent and being measured with a mass spectrometer, the method including, a derivatization step of derivatizing n number of samples by using n types of 4-(4?-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione (DAPTAD) isotopologues respectively as derivatization reagents, a mixing step of mixing the n types of derivatization samples obtained in the derivatization step, and a quantitative analysis step of subjecting each of the n types of vitamin D derivatives contained in the mixed sample obtained in the mixing step to quantitative analysis using a mass spectrometer.
Type:
Grant
Filed:
November 15, 2017
Date of Patent:
December 7, 2021
Assignees:
Tokyo University of Science, National University Corporation Chiba University, JEOL Ltd.
Abstract: Polycrystalline magnesium silicide containing only carbon as a dopant and having carbon distributed at the crystal grain boundaries and within the crystal grains, a thermoelectric conversion material obtained using the polycrystalline magnesium silicide, a sintered compact, a thermoelectric conversion element, and a thermoelectric conversion module, and methods for producing polycrystalline magnesium silicide and a sintered compact.
Abstract: A three-dimensional printing system (1) includes: a head (2) to which a first continuous material (FL) including a resin and a second continuous material (FB) including fibers are fed; a platform (3) on which a printing material based on the first and second continuous materials from the head is stacked; a cutting device (10) which is capable of cutting at least fibers; and a controller (5) which controls an operation device including at least one of the head, the platform, and the cutting device.
Type:
Grant
Filed:
May 27, 2015
Date of Patent:
August 31, 2021
Assignees:
Nihon University, Tokyo University of Science Foundation
Abstract: An energy-sensitive composition including at least one of a silane compound monomer capable of forming a polysilane compound, a silane compound oligomer and the polysilane compound, and a base generator (B) represented by the following formula (1): in which R1 to R11 each independently represents a hydrogen atom, a halogen atom, a nitro group, an alkyl group, an aryl group, an arylalkyl group or an alkoxy group, R5 and R6 may be connected to each other via a single bond or a divalent linking group, Zq+ represents a q-valent counter cation composed of a base having a pKa of 24 or more, and q represents an integer of 1 or more.
Type:
Grant
Filed:
April 22, 2019
Date of Patent:
August 31, 2021
Assignees:
Tokyo Ohka Kogyo Co., Ltd., Tokyo University of Science Foundation
Inventors:
Kunihiro Noda, Dai Shiota, Koji Arimitsu
Abstract: To provide a moth-eye transfer mold and a method of manufacturing a moth-eye transfer mold that provide a simple and inexpensive manufacturing process. A moth-eye transfer mold 1 is characterized by including a base 10, an underlayer 20 formed on the base 10, and a glassy carbon layer 30 formed on the underlayer 20, the glassy carbon layer 30 has an inverted moth-eye structure RM over a surface 30a, and the inverted moth-eye structure RM is randomly arranged cone-shaped pores.
Type:
Grant
Filed:
June 12, 2019
Date of Patent:
August 17, 2021
Assignees:
Tokyo University of Science Foundation, GEOMATEC CO., LTD.
Abstract: A Ras protein degradation inducing molecule that can induce degradation of Ras proteins, and a pharmaceutical composition that contains this Ras protein degradation inducing molecule are provided. The Ras protein degradation inducing molecule is a conjugate of a Ras protein affinity molecule which has affinity to Ras proteins, and a proteolysis-inducing tag which has affinity to protease and does not inhibit proteolysis of proteins by the protease.
Abstract: A p53 degradation inducing molecule which can induce degradation of p53 proteins or p53 composites, and a pharmaceutical composition containing said p53 degradation inducing molecule are provided. This p53 degradation inducing molecule is a conjugate of a p53 affinity molecule which has affinity for p53 proteins or p53 composites, and a proteolysis induction tag which has affinity for protease and which does not inhibit proteolysis of proteins by protease.
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: Provided are: a protein degradation inducing tag which is a molecule that has affinity with proteases and does not inhibit degradation of a protein by proteases; a protein degradation inducing molecule that is a conjugate of at least one protein degradation inducing tag and at least one protein binding molecule that binds to a protein; and a usage of those.
Abstract: In a control device for a switched reluctance motor, a voltage drop control is executed in which a voltage dropped to be lower than a voltage applied in a case where the switched reluctance motor is driven in a high-load region is applied to the switched reluctance motor, in a case where the switched reluctance motor is driven in a low-load region. The low-load region is a lower load region than the high-load region.
Type:
Grant
Filed:
October 2, 2017
Date of Patent:
February 2, 2021
Assignees:
TOYOTA JIDOSHA KABUSHIKI KAISHA, Tokyo University of Science Foundation
Abstract: Provided is a method for derivatizing an s-cis-diene compound with a Cookson-type derivatization reagent, the method including adding, in a reaction stopping step of stopping a derivatization reaction of the s-cis-diene compound, a decomposition inhibitor to inhibit decomposition of a derivative to be obtained.
Type:
Grant
Filed:
September 28, 2017
Date of Patent:
September 1, 2020
Assignees:
Tokyo University of Science, National University Corporation Chiba University, JEOL Ltd.
Abstract: Provided are: a pharmaceutical composition for curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor, in which the pharmaceutical composition contains a carbohydrate modifying enzyme as an active ingredient; and a method of curing, treating, or preventing a disease involving a biological mechanism controlled by a dendritic cell immunoreceptor.
Abstract: Provided is a hydrogen recovery method such that highly concentrated hydrogen gas can be obtained efficiently by adsorbing and removing hydrocarbon gas such as carbon dioxide, carbon monoxide, and methane, using a relatively low pressure, from pyrolysis gas obtained by heat treating biomass. The present invention is the method for recovering hydrogen from pyrolysis gas obtained by heat treating biomass, characterized by including: a first purifying step of adsorbing and removing gas that mainly includes carbon dioxide under pressure from the pyrolysis gas to purify the pyrolysis gas; and a second purifying step of further adsorbing and removing gas that includes carbon dioxide under pressure from purified gas obtained by the first purifying step at a pressure lower than the pressure in the first purifying step to purify the purified gas in order to recover hydrogen from the purified gas.
Type:
Grant
Filed:
October 28, 2015
Date of Patent:
July 28, 2020
Assignees:
Japan Blue Energy Co., Ltd., Tokyo University of Science Foundation
Abstract: Organic colorant represented by General Formula (1) below: where in the General Formula (1), R1 and R2 each independently represent C1-C20 alkyl group, C1-C20 alkenyl group, phenyl group, naphthyl group, or group represented by —(CH2)n—COO—R3, —(CH2)n—R4, —(CH2)n—CONH—R5, —CR6R7—COO—R8, or —(CH2)n—OCOCH3; R3 represents hydrogen atom or C1-C2 alkyl group; R4 represents hydroxy group, C1-C2 alkoxy group, C2-C5 alkenyloxy group, SO3Na group, OSO3Na group, phenyl group, phenylalkyl group, naphthyl group, or naphthylalkyl group; R5 represents C1-C20 alkyl group, C1-C20 alkenyl group, or C1-C12 hydroxyalkyl group; R6 represents hydrogen atom or methyl group; R7 represents C1-C4 alkyl group; R8 represents C1-C5 alkyl group; and n is integer of from 1 to 12.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
July 7, 2020
Assignees:
Ricoh Company, Ltd., Tokyo University of Science Foundation
Abstract: The present invention provides a new hydrogen chloride removing agent that exhibits a good hydrogen chloride removal effect at a relatively low temperature. The present invention preferably provides a new hydrogen chloride removing agent for removing hydrogen chloride contained in a hydrogen-chloride-containing gas, such as a pyrolysis gas, a combustion exhaust gas, a dry distillation gas, etc., especially hydrogen chloride contained in a biomass pyrolysis gas. The present invention relates to a hydrogen chloride removing agent characterized by containing a mixture of a calcium carbonate and an imogolite and/or a synthetic imogolite, and relates to a method for removing, by using said hydrogen chloride removing agent, hydrogen chloride contained in a hydrogen-chloride-containing gas, especially hydrogen chloride contained in a biomass pyrolysis gas.
Type:
Application
Filed:
July 20, 2017
Publication date:
June 11, 2020
Applicants:
Japan Blue Energy Co., Ltd., Tokyo University of Science Foundation
Abstract: An inkjet ink including: a stilbene-based compound represented by General Formula (1) below; where in the General Formula (1), R1 and R3 each independently represent, for example, an alkyl group including 1 to 20 carbon atoms, an alkenyl group including 1 to 20 carbon atoms, a phenyl group, or a naphthyl group.
Type:
Grant
Filed:
October 3, 2017
Date of Patent:
May 19, 2020
Assignees:
Ricoh Company, Ltd., Tokyo University of Science Foundation
Abstract: Provided is a concrete composition, including: blast furnace slag; at least any one of expansive additive and cement; and water, wherein a unit water content of the water is 130 kg/m3 or less; wherein a content of the cement is 22% by mass or less relative to the blast furnace slag, and wherein a slump flow value of the concrete composition is 40 cm or greater.
Type:
Application
Filed:
April 11, 2018
Publication date:
April 16, 2020
Applicants:
SUMITOMO MITSUI CONSTRUCTION CO., LTD., The University of Tokyo, Tokyo University of Science Foundation
Abstract: An object of the present disclosure is to provide a fuel cell separator having a low contact resistance due to a tin oxide film and having an excellent corrosion resistance. An embodiment is a method for manufacturing a fuel cell separator including a stainless steel substrate. The method includes forming the tin oxide film on a surface of the stainless steel substrate; and attaching phosphoric acid or phosphate to at least a defective portion in the tin oxide film.
Type:
Application
Filed:
June 18, 2019
Publication date:
January 2, 2020
Applicants:
TOYOTA JIDOSHA KABUSHIKI KAISHA, Tokyo University of Science Foundation