Abstract: The present invention provides a transport container comprising; a first container having a first inner wall with a storage space for storing a transported object and a first outer wall provided on the outside of the first inner wall so as to form, with the first inner wall, a vacuum space therebetween; a first lid that is heat-insulating and is for removably sealing a first opening of the first container; a second container having a second inner wall with a space for storing the first container and the first lid and a second outer wall provided on the outside of the second inner wall so as to form, with the second inner wall, a vacuum space therebetween; a second lid that is heat-insulating and is for removably sealing a second opening of the second container; and a heat storage material for surrounding the transported object inside the storage space.

Abstract: Crystals of (2S)-2-((4-((4-((1S)-1,2-dihydroxyethyl)phenyl)ethynyl)benzoyl)(methyl)amino)-N-hydroxy-N?,2-dimethylmalonamide having diffraction peaks at diffraction angles (2?) of 3.8±0.2°, 7.7±0.2°, and 10.8±0.2°, etc., or 8.2±0.2°, 12.4±0.2°, and 13.3±0.2°, etc., in powder X-ray diffraction, a production method thereof, and a pharmaceutical composition.

Abstract: A novel method for production of hydroxamic acid derivative using a compound represented by the formula [12] as an intermediate, and intermediate therefor. wherein R1 represents a methyl group or the like; R2 represents a methyl group or the like; and R5 represents a hydrogen atom or the like.

Abstract: Provided are a medicine audit apparatus, a medicine audit method, and a program capable of detecting a state where recognition of a medicine is impossible from a captured image obtained by imaging the medicine and urging a user to pay attention in the case of the state where the medicine recognition is impossible.

Abstract: An object of the present invention is to provide a drug which prevents progress of Alzheimer's disease and a method of preventing progress of Alzheimer's disease. 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof has an effect of suppressing brain atrophy and is useful as an agent for preventing or treating brain atrophy. Brain atrophy observed in aging or neurodegenerative diseases can be prevented or treated by administering 1-(3-(2-(1-Benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof.

Abstract: A compound represented by the general formula, or a salt thereof, has exceptional CXCL10 inhibitory activity and is useful as a treatment agent for the prevention and/or treatment, etc., of diseases involving overproduction of CXCL10. In the formula: R1 is a C1-6 alkyl group, etc.; R2 is a hydrogen atom, etc.; R3 is a halogen atom, etc.; Z1, Z2, and Z3 are CH, etc.; X1 is CONH, etc.; ring A is a phenyl group, etc.; R4 is a halogen atom, etc.; and m is an integer of 0-5.

Abstract: A medicine inspection device, an image processing device, an image processing method, and a program are provided that appropriately extract identification information even when the positional relationship between a printed character and an engraved mark added to a medicine is not constant. The above problem is solved by an image processing device that performs a process of enhancing a printed character portion of a medicine based on at least one image taken with a surface of the medicine being irradiated with light to generate a printed-character-enhanced image, performs a process of extracting only an engraved mark portion from a three-dimensional shape of the medicine based on at least three images taken with illumination directions of the light to the surface of the medicine different from each other to generate an engraved-mark-extracted image, and generates a difference image between the printed-character-enhanced image and the engraved-mark-extracted image.

Abstract: A medicine inspection assistance device, an image processing device and an image processing method are provided that appropriately recognize identification information irrespective of whether the identification information is an engraved mark or a printed character. The image processing device that obtains a plurality of taken images of a medicine, performs a process of enhancing an engraved mark portion of the medicine based on at least one taken image among the taken images and generates a first enhanced image, performs a process of enhancing a printed character portion of the medicine based on at least one taken image among the taken images and generates a second enhanced image, collates an integrated image obtained by integrating the first enhanced image and the second enhanced image with each other, with a master image, and determines whether the medicine to be dispensed and the dispensed medicine are identical to each other or not.

Abstract: A medicine inspection support device, an image processing device, an image processing method and a program are provided that appropriately recognize identification information irrespective of whether the identification information is an engraved mark or a printed character. The image processing device obtains a plurality of taken images of a second medicine with light illumination directions to the surface of the second medicine different from each other, generates a first enhanced image by performing a process of enhancing an engraved mark portion of the second medicine, generates a second enhanced image by performing a process of enhancing a printed character portion of the second medicine, and collates the image designated by the designation information designating one of the first enhanced image and the second enhanced image as an image to be used for collation with the master image to determine whether the first medicine is identical to the second medicine.

Abstract: Provided is a compact lightweight transport box in which the internal temperature distribution is minimized and accurate temperature regulation can be performed. The transport box includes an insulating container, an internal heat conducting container mounted in the insulating container, and an insulating cover body with a cover internal side heat conducting plate exposed on an inner surface facing the opening part of the internal heat conducting container, in which, with the opening part of the insulating container closed by the insulating cover body, the cover internal side heat conducting plate is near an opening end of the internal heat conducting container.

Abstract: An object of the present invention is to provide a drug and a method which suppress progress of tauopathy such as Alzheimer's disease. 1-(3-(2-(1-Benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof has an effect of reducing the amount of phosphorylated tau protein and an effect of reducing the amount of amyloid ? protein in the brain parenchyma, and thus is effective as an agent for preventing or treating tauopathy. Tauopathy can be prevented or treated by administering 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof.

Abstract: A image processing device which can reduce information such as a pattern, a scar and the like on a surface of a drug which are other than an engraved mark, to accurately extract the engraved mark. The image processing device includes: an obtaining unit configured to obtain a plurality of images of a drug having an engraved mark on a surface of the drug, with emitting directions of light to the surface different from each other; an edge image generating unit configured to apply respectively to the plurality of images, edge extracting filters in directions in conformity with the emitting directions, the edge extracting filters having a size in conformity with a width of a groove of the engraved mark, and generate a plurality of edge images; and an image composing unit configured to compose the plurality of edge images and generate a composite image.

Abstract: A drug identification device, an image processing device, an image processing method, and a program are provided that appropriately determine whether identification information added to a drug is added by mark engraving or by character printing. The above problem is solved by an image processing device including: an obtaining unit configured to obtain a plurality of images of a drug having identification information added by mark engraving or by character printing on a surface of the drug, with emitting directions of light to the surface different from each other; an image comparing unit configured to compare the plurality of images with each other; and a determining unit configured to determine whether the identification information is added by mark engraving or by character printing, according to a comparison result by the image comparing unit.

Abstract: A compound represented by the general formula, or a salt thereof, has exceptional CXCL10 inhibitory activity and is useful as a treatment agent for the prevention and/or treatment, etc., of diseases involving overproduction of CXCL10. In the formula: R1 is a C1-6 alkyl group, etc.; R2 is a hydrogen atom, etc.; R3 is a halogen atom, etc.; Z1, Z2, and Z3 are CH, etc.; X1 is CONH, etc.; ring A is a phenyl group, etc.; R4 is a halogen atom, etc.; and m is an integer of 0-5.

Abstract: An object of the present invention is to provide a drug which prevents progress of Alzheimer's disease and a method of preventing progress of Alzheimer's disease. Alzheimer's disease can be effectively prevented or treated by initiating administration of a pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof as an active ingredient to a patient within a certain period from clinical diagnosis of Alzheimer's disease.

Abstract: The present invention can ensure traceability of packaged drugs. A label printer of a drug packaging apparatus provided in a dispensing pharmacy or the like prints unique identification information, which is only one in the world issued by a numbering server on a package basis, on a label, and attaches the label to a packaging bag in which drugs are packaged by a drug packing unit. The dispensing pharmacy uploads at least drug information of the packaged drugs, to which the unique identification information is added, to a cloud server in association with the unique identification information. The cloud server unitarily manages the drug information of the packaged drugs uploaded from the dispensing pharmacy or the like in association with the unique identification information. The packaged drugs can be traced by making inquiries to the cloud server based on the unique identification information added to the packaging bag.

Abstract: An object of the present invention is to provide an excellent drug for preventing or treating spinocerebellar ataxia. 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof has an effect of suppressing brain atrophy, especially cerebellar atrophy, and is useful as an agent for preventing or treating spinocerebellar ataxia. Cerebellar atrophy observed in spinocerebellar ataxia can be prevented or treated by administering 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof.

Abstract: An object of the present invention is to provide a compound or a salt thereof which shows strong antibacterial activity and has excellent solubility in water, and a lyophilized formulation, an LpxC inhibitor, and an antibacterial agent comprising the compound or a salt thereof. The present invention provides a compound represented by the Formula [1] or a salt thereof: wherein R1 represents a hydrogen atom or the like, R2 represents a hydrogen atom or the like, R3 represents a hydrogen atom or the like, R4 represents a hydrogen atom or the like, and n represents 0 or 1.

Abstract: The drug inspection assisting apparatus includes: a drug collating unit configured to collate a reference image of each drug listed in the prescription and a collation-target image based on a captured image of drugs packaged in the packaging bag and determine whether or not the drug shown by the collation-target image and the drug shown by the reference image are the same drug; a listing-table creating unit configured to create, for each kind of the drugs to be packaged in the packaging bag, a listing table including the reference image of drug to be dispensed according to the prescription and all images which are determined to show the same drug as the drug shown by the reference image, among collation-target images; and a display control unit configured to cause a display device to display the listing table for a single kind of drug on a display screen.

Abstract: An object of the present invention is to provide a dispensing audit support apparatus and a dispensing audit support method with a high collation accuracy robustness. According to a dispensing audit support apparatus according to one aspect of the present invention, since a position, shape and size of a region of interest are set according to a position of a collation-target medicine in a captured image, and a position, shape and size of a master image are set according to the set region of interest, it is possible to avoid or reduce distortion of the medicine shape, blur, inclusion of an end part into the image, and the like due to the position and orientation of the collation-target medicine. Therefore, influence on collation accuracy is small, and it is possible to enhance the robustness of the collation accuracy.