Patents Assigned to Toyo Suisan Kaisha Ltd.
  • Publication number: 20040109926
    Abstract: A method of preparing food to be cooked under heat or food cooked under heat, which is capable of decreasing acrylamide contained in the food after the cooking, wherein the method comprises adding to the food at least one compound selected from the group consisting of (a1) neutral amino acids and salts thereof, (a2) basic amino acids and salts thereof, (a3) neutral imino acids and salts thereof, (b) sulfonic acids and salts thereof and/or at least one peptide complex of peptides having, as constituting components thereof, any one of the amino acids of the items (a1) to (a3).
    Type: Application
    Filed: December 1, 2003
    Publication date: June 10, 2004
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Yoshio Tomoda, Akihiro Hanaoka, Toshitaka Yasuda, Tomo Takayama, Ado Hiwatashi
  • Publication number: 20040105929
    Abstract: Instant fried noodles with lowered acrylamide. This fried noodles may be prepared by a method comprising kneading a mixture of raw materials containing a cereal flour to prepare noodle dough, preparing strands of noodle with the noodle dough, and frying the strands of noodle to prepare fried noodles, wherein pH of the noodle dough and/or pH of the strands of noodle before the frying is so controlled that a pH value of the fried noodles is 6.5 or less.
    Type: Application
    Filed: November 10, 2003
    Publication date: June 3, 2004
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Yoshio Tomoda, Akihiro Hanaoka, Toshitaka Yasuda, Tomo Takayama
  • Publication number: 20040102605
    Abstract: Peptides having, as constitutive amino acids, (1) 4 glutamine residues, 1 glutamic acid residue, 1 serine residue, 2 valine residues, 1 isoleucine residue and 5 leucine residues, and having a 3-hydroxydecanoyl group bonded, via an amide linkage, to the N-terminal leucine residue thereof; (2) 4 glutamine residues, 1 glutamic acid residue, 1 serine residue, 3 valine residues, and 5 leucine residues, and having a 3-hydroxydecanoyl group bonded, via an amide linkage, to the N-terminal leucine residue thereof; or (3) 4 glutamine residues, 1 glutamic acid residue, 1 serine residue, 2 valine residues, 1 isoleucine residue and 5 leucine residues, and having a 3-hydroxydodec-5-enoyl group bonded, via an amide linkage, to the N-terminal leucine residue thereof. The peptides have an antiviral activity. A strain capable of producing the above peptides and belonging to a new species of genus Pseudomonas.
    Type: Application
    Filed: July 31, 2003
    Publication date: May 27, 2004
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Masahiro Ishima, Tsutomu Yoshida, Takayuki Yamazaki, Fumio Sugawara, Kiyoshige Hatta, Manabu Shimojoe, Kazuyoshi Masaki
  • Patent number: 6740640
    Abstract: Sulfofucosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a higher fatty acid. The derivatives represented by General formula (1) are useful as a DNA polymerase inhibitor and an anticancer agent.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: May 25, 2004
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Publication number: 20040093169
    Abstract: A method of designing a molecular structure of an inhibitor of a target enzyme by analyzing, in the tertiary structure of a first enzyme, a geometric configuration formed by amino acids to which an inhibitor on the first enzyme is to bind. The method comprises (1) a step of determining the amino acid group of the first enzyme to which the inhibitor is to bind, (2) a step of determining the geometric configuration of the amino acid group of the step (1), (3) a step of searching for an amino acid group having a geometric configuration similar to that of the step (2), in the target enzyme, and (4) a step of searching weather or not (i) the amino acids constituting the amino acid group are present at the surface of the target enzyme, and (ii) the amino acids have been conserved in different species by comparison with an enzyme derived from an organism of different types from the organism from which the target enzyme is derived.
    Type: Application
    Filed: May 29, 2003
    Publication date: May 13, 2004
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Yoshiyuki Mizushina, Kengo Sakaguchi, Fumio Sugawara
  • Publication number: 20040067893
    Abstract: A method for treating a cancer. The cancer excluding an adenocarcinoma and being epithelioma, glioma, sarcoma, melanoma, lymphoma or leukemia; or the cancer is an adenocarcinoma cancer excluding colon cancer, lung cancer and gastric cancer.
    Type: Application
    Filed: October 2, 2003
    Publication date: April 8, 2004
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Patent number: 6670361
    Abstract: An anticancer drug includes a compound represented by Formula (1): where R101 represents an acyl moiety of a saturated higher fatty acid, and R102 represents a hydrogen atom or an acyl moiety of a saturated higher fatty acid, and/or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: December 30, 2003
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi
  • Patent number: 6518410
    Abstract: A method for immunosuppression in a subject comprising administering to the subject in need thereof, a pharmaceutically effective amount of at least one sulfoquinovosylacylglycerol derivative represented by General formula (1-1): wherein R101 represents an acyl residue of a higher fatty acid, and R102 represents a hydrogen atom or an acyl residue of a higher fatty acid; and a pharmaceutically acceptable salt thereof. Of the sulfoquinovosylacylglycerol derivatives, &bgr;-sulfoquinovosylacylglycerols are novel compounds. The present invention also relates to pharmaceutical composition comprising a pharmaceutically effective amount of the &bgr;-sulfoquinovosylacylglycerols and/or its pharmaceutically acceptable salt; and a pharmaceutically acceptable excipient. The pharmaceutical composition may be used as an immunosuppressive agent, anticancer agent and DNA polymerase &agr; inhibitor.
    Type: Grant
    Filed: September 10, 2001
    Date of Patent: February 11, 2003
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Patent number: 6518248
    Abstract: An anticancer drug includes a compound represented by Formula (1): where R101 represents an acyl moiety of a saturated higher fatty acid, and R102 represents a hydrogen atom or an acyl moiety of a saturated higher fatty acid, and/or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: February 11, 2003
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi
  • Publication number: 20020173471
    Abstract: An anticancer drug includes a compound represented by Formula (1): 1
    Type: Application
    Filed: January 14, 2002
    Publication date: November 21, 2002
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi
  • Patent number: 6444795
    Abstract: 1-O-(2-propenyl)-6-O-sulfonylpyranoside represented by the formula wherein R1, R2 and R3 each independently represents an alkyl or substituted silyl group, and R4 represents an alkylsulfonyl or arylsulfonyl group.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: September 3, 2002
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi
  • Patent number: 6395886
    Abstract: 1-O-(2-propenyl)-6-deoxy-6-carbonylthiopyranoside represented by the formula wherein R1, R2 and R3 each independently represents an alkyl or a substituted silyl group, and R5 represents a hydrogen atom, or an alkyl or aryl group.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: May 28, 2002
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi
  • Publication number: 20020052327
    Abstract: A method for immunosuppression in a subject comprising administering to the subject in need thereof, a pharmaceutically effective amount of at least one sulfoquinovosylacylglycerol derivative represented by General formula (1-1): 1
    Type: Application
    Filed: September 10, 2001
    Publication date: May 2, 2002
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Publication number: 20020028777
    Abstract: Novel sulfofucosylacylglycerol derivatives represented by General Formula (1): 1
    Type: Application
    Filed: August 24, 2001
    Publication date: March 7, 2002
    Applicant: TOYO SUISAN KAISHA, LTD
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Publication number: 20020028776
    Abstract: A medicament containing at least one compound selected from the group consisting of compounds represented by General formula (1): 1
    Type: Application
    Filed: August 22, 2001
    Publication date: March 7, 2002
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Publication number: 20020022597
    Abstract: Novel sulforhamnosylacylglycerol derivatives represented by General Formula (1): 1
    Type: Application
    Filed: August 24, 2001
    Publication date: February 21, 2002
    Applicant: TOYO SUISAN KAISHA, LTD.
    Inventors: Takayuki Yamazaki, Fumio Sugawara, Keisuke Ohta, Kazuyoshi Masaki, Kotaro Nakayama, Kengo Sakaguchi, Noriyuki Sato, Hiroeki Sahara, Tatsuya Fujita
  • Patent number: 5727925
    Abstract: An apparatus according to the present invention comprises a lift mechanism provided at the end of an introducing-aligning conveyor mechanism and a shutter mechanism overlying the lift mechanism. A plurality of cases are arranged in alignment on the conveyor mechanism. The cases are pushed up by the lift mechanism and supported by the shutter mechanism. When cases of another set are then aligned on the introducing-aligning conveyor mechanism, the shutter mechanism opens, so that the cases supported thereon fall to be stacked on the second set. The stacked cases are pushed up by the lift mechanism and supported by the shutter mechanism. These processes of operation are repeated so that the cases are stacked in layers.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: March 17, 1998
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Yuji Ozawa, Sadami Tabata, Masaru Chiwaki
  • Patent number: 5534273
    Abstract: A method for manufacturing packed wet-type instant noodles of a double-layered structure which is simple in structure as compared with a three-ply structure, excellent in smoothness, tenacity and softness, and have improved elasticity and firmness. This method comprises the steps of, forming a first noodle strip from a dough obtained by kneading in vacuum a first raw material containing an alkaline agent and raw powders consisting mainly of wheat flour and starch, forming a second noodle strip from a dough obtained by kneading a second raw material in a vacuum higher in degree than that employed in kneading the first raw material, the second raw material containing alginic acid or alginate, an alkaline agent and raw powders consisting mainly of wheat flour and 7.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: July 9, 1996
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventors: Youichi Ito, Akihiro Hanaoka, Kenichi Tezuka
  • Patent number: 5042369
    Abstract: Instant noodles which are formed in a block of a plurality of noodles having a plurality of indented portions in the longitudinal direction and separate at the indented portions into short noodles upon cooking in a cooking pot containing boiling water.
    Type: Grant
    Filed: September 12, 1990
    Date of Patent: August 27, 1991
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventor: Yoshio Tomoda
  • Patent number: 4988528
    Abstract: Instant noodles which are formed in a block of a plurality of noodles having a plurality of indented portions in the longitudinal direction and separate at the indented portions into short noodles upon cooking in a cooking pot containing boiling water.
    Type: Grant
    Filed: July 31, 1989
    Date of Patent: January 29, 1991
    Assignee: Toyo Suisan Kaisha, Ltd.
    Inventor: Yoshio Tomoda