Abstract: A photonic beamformer is disclosed and is configured to transmit or receive a plurality of RF input signals from a plurality of antennas. The beamformer receiver includes a plurality of optical modulators, each optical modulator being configured to modulate each of the RF input signals onto an optical carrier, each carrier having a different wavelength. The beamformer receiver also includes a plurality of optical amplifiers, each optical amplifier being configured to vary the optical power of one optical carrier based on a weighting input and generate a weighted optical carrier. The beamformer receiver also includes a plurality of multi-beam optical true-time delays (TTD), each TTD being configured to receive all of the weighted optical carriers and generate a plurality time delayed optical carriers.
Type:
Application
Filed:
August 26, 2015
Publication date:
March 2, 2017
Applicant:
The Trustees of Princeton University
Inventors:
Paul Prucnal, Matthew Chang, John Chang
Abstract: Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof derived from 6G8G7 and 7C5B2 anti-DEspR variant antibodies, including fully human, composite engineered human, humanized, monoclonal, and polyclonal anti-DEspR antibodies and fragments thereof, and methods of their use in a variety of therapeutic applications. The compositions comprising the anti-DEspR antibodies and fragments thereof described herein are useful in diagnostic and imaging methods, such as DEspR-targeted molecular imaging of angiogenesis, and for companion diagnostic and/or in vivo non-invasive imaging and/or assessments.
Type:
Application
Filed:
August 24, 2016
Publication date:
March 2, 2017
Applicant:
Trustees of Boston University
Inventors:
Nelson Ruiz-Opazo, Victoria L.M. Herrera
Abstract: Aspects of the present disclosure are directed to apparatuses, systems and methods involving imaging providing pixel intensity ratios using circuitry. According to an example embodiment, an apparatus includes a photosensor array having an array of sensors and a circuitry. Each sensor of the photosensor array provides a signal value for a pixel that is indicative of an intensity of light detected. Further, the circuitry responds to the signal values from a plurality of sensors of the photosensor array, by converting signals indicative of a ratio of pixel intensity values to a digital signal that characterize at least an edge of an object corresponding to or associated with the intensity of the detected light. The circuitry provides digital signals, each indicative of a ratio of pixel intensity values, for respective sensors of the photosensor array.
Type:
Application
Filed:
February 27, 2015
Publication date:
March 2, 2017
Applicant:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A quantitative gait training and/or analysis system includes a pair of footwear modules that may include a shank module and an independent processing module. Each footwear module may have a sole portion, a heel portion, a speaker, vibrotactile transducer and a wireless communication module. Sensors may permit the extraction of gait kinematics in real time and provide feedback from it. Embodiments may store data for later reduction and analysis. Embodiments employing calibration-based estimation of kinematic gait parameters are described.
Type:
Application
Filed:
April 22, 2015
Publication date:
March 2, 2017
Applicant:
The Trustees of Columbia University in the City of New York
Inventors:
Sunil K. AGRAWAL, Damiano ZANOTTO, Emily M. BOGGS
Abstract: The present invention relates to methods for treating or preventing a mitral valve disease in a subject in need thereof, comprising administering to the subject an effective amount of a therapeutic agent. The therapeutic agent is capable of suppressing serotonin receptor signaling. The methods may be combined with a mitral valve surgery, serotonin transporter polymorphism genotyping, MV disease diagnosis, and/or an adjunct assay. Also provided are related medicaments, pharmaceutical compositions, and methods for preparing the medicaments.
Type:
Application
Filed:
March 3, 2015
Publication date:
March 2, 2017
Applicants:
The Children's Hospital of Philadelphia, The Trustees of the University of Pennsylvania
Abstract: Techniques are disclosed for determining a specific velocity of a device attached to a wireless network. The specific velocity can be determined using a handover count of the base station boundary transitions over a time window and/or using a set of sojourn time samples that each denote the duration the device remains in the zone of a particular base station. Techniques operate effectively in cellular networks having high base station densities. The specific velocity estimates may be inputs to components on the device or network to adjust a local device function or performance behavior.
Type:
Grant
Filed:
June 24, 2015
Date of Patent:
February 28, 2017
Assignee:
The Florida International University Board of Trustees
Abstract: Provided is a phase change memory device including a graphene layer inserted between a lower electrode into which heat flows and a phase change material layer, to prevent the heat from being diffused to an outside so as to efficiently transfer the heat to the phase change material layer, and a method of fabricating the phase change memory device. The phase change memory device includes a lower electrode; an insulating layer formed to enclose the lower electrode; a graphene layer formed on the lower electrode; a phase change material layer formed on the graphene layer and the insulating layer; and an upper electrode formed on the phase change material layer. Since a phase of the phase change material layer is changed at a small amount of driving current, the phase change memory device is fabricated to have a high driving speed and a high integration.
Type:
Grant
Filed:
January 29, 2016
Date of Patent:
February 28, 2017
Assignees:
Samsung Electronics Co., Ltd., The Board of Trustees of the Leland Stanford Junior University
Inventors:
Yongsung Kim, Chiyui Ahn, Aditya Sood, Eric Pop, H.-S. Philip Wong, Kenneth E. Goodson, Scott Fong, Seunghyun Lee, Christopher M. Neumann, Mehdi Asheghi
Abstract: Detection of neurological diseases such as Parkinson's disease can be accomplished through analyzing a subject's speech for acoustic measures based on human factor cepstral coefficients (HFCC). Upon receiving a speech sample from a subject, a signal analysis can be performed that includes identifying articulation range and articulation rate using HFCC and delta coefficients. A likelihood of Parkinson's disease, for example, can be determined based upon the identified articulation range and articulation rate of the speech.
Type:
Grant
Filed:
October 9, 2013
Date of Patent:
February 28, 2017
Assignees:
University of Florida Research Foundation, Incorporated, Board of Trustees of Michigan State University
Inventors:
John Clyde Rosenbek, Mark D. Skowronski, Rahul Shrivastav, Supraja Anand
Abstract: Intravenous ferumoxytol is used to effectively label mesenchymal stem cells (MSCs) in vivo and is used for in vivo tracking of stem cell transplants with magnetic resonance (MR) imaging. The method eliminates risk of contamination and biologic alteration of MSCs associated with ex-vivo-labeling procedures.
Type:
Grant
Filed:
January 22, 2014
Date of Patent:
February 28, 2017
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A gas reactor device includes a plurality of microcavities or microchannels defined at least partially within a thick metal oxide layer consisting essentially of defect free oxide. Electrodes are arranged with respect to the microcavities or microchannels to stimulate plasma generation therein upon application of suitable voltage. One or more or all of the electrodes are encapsulated within the thick metal oxide layer. A gas inlet is configured to receive feedstock gas into the plurality of microcavities or microchannels. An outlet is configured to outlet reactor product from the plurality of microcavities or microchannels. In an example preferred device, the feedstock gas is air or O2 and is converted by the plasma into ozone (O3). In another preferred device, the feedstock gas is an unwanted gas to be decomposed into a desired form. Gas reactor devices of the invention can, for example, decompose gases such as CO2, CH4, or NOx.
Type:
Grant
Filed:
January 7, 2015
Date of Patent:
February 28, 2017
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
J. Gary Eden, Sung-Jin Park, Jin Hoon Cho, Seung Hoon Sung, Min Hwan Kim
Abstract: A prodrug having antioxidant activity, including a phosphorylated compound having a thiol group. A method of treating oxidative stress by administering a prodrug of a phosphorylated compound including a thiol group, removing a phosphate group of the prodrug, and treating oxidative stress. A method of increasing bioavailability of a thiol compound by creating a prodrug by phosphorylating a thiol compound, administering the prodrug, preventing first pass metabolism of the prodrug, removing a phosphate group from the prodrug, and providing active drug to a site in need of therapy from oxidative stress. A method of preventing radiation damage to healthy tissue by administering a prodrug comprising a phosphorylated compound including a thiol group, removing a phosphate group of the prodrug to provide active drug, and preventing radiation damage to healthy tissue.
Type:
Grant
Filed:
April 23, 2015
Date of Patent:
February 28, 2017
Assignee:
Board of Trustees of Northern Illinois University
Abstract: A method for producing an amphiphilic particle or an anisotropic particle includes combining seed particles with a monomer emulsion to obtain monomer-swollen seed particles, polymerizing the monomer-swollen seed particles to obtain polymerized monomer-swollen particles, and hydrolyzing the polymerized monomer-swollen particles. An amphiphilic particle is adapted to stabilize a first type of multiphasic mixture comprising a first aqueous phase having a first pH and a second type of multiphasic mixture comprising a second aqueous phase having a second pH.
Type:
Grant
Filed:
April 15, 2015
Date of Patent:
February 28, 2017
Assignee:
The Trustees of the University of Pennsylvania
Abstract: The present disclosure describes methods for preventing or treating periodontitis or diseases associated with periodontitis. The present disclosure also describes methods of screening for compounds that can be used to prevent or treat periodontitis or diseases associated with periodontitis.
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
February 28, 2017
Assignee:
The Trustees of the University of Pennsylvania
Abstract: This invention provides a nucleotide analogue comprising (i) a base selected from the group consisting of adenine, guanine, cytosine, thymine and uracil, (ii) a deoxyribose, (iii) an allyl moiety bound to the 3?-oxygen of the deoxyribose and (iv) a fluorophore bound to the base via an allyl linker, and methods of nucleic acid sequencing employing the nucleotide analogue.
Type:
Application
Filed:
March 17, 2016
Publication date:
February 23, 2017
Applicant:
The Trustees of Columbia University in the City of New York
Inventors:
Jingyue Ju, Lanrong Bi, Dae H. Kim, Qinglin Meng
Abstract: Systems and techniques are described to enable the dynamic selection of a transit route through the stop zones of a transit line. Techniques are disclosed for receiving a current location of a transit vehicle on a transit line and determining a transit route through one or more of the vehicle's remaining stop zones by choosing an optimized combination of stop options and route segment options for that specific transit vehicle. Techniques may be performed in some cases by accessing a real-time traffic information service to obtain one or more traffic condition factors on a route segment, determining a dynamic route segment option weight, calculating a dynamic cost function with respect to the weights, and determining an optimized set of the route segments with respect to the cost functions.
Type:
Application
Filed:
August 18, 2015
Publication date:
February 23, 2017
Applicant:
The Florida International University Board of Trustees
Inventors:
Oliver ULLRICH, Naphtali RISHE, Daniel LUCKERATH
Abstract: A wind turbine platform configured to float in a body of water and support a wind turbine thereon includes a buoyant hull platform. A wind turbine tower is centrally mounted on the hull platform and a wind turbine is mounted to the wind turbine tower. An anchor is connected to the hull platform and to the seabed, and a weight-adjustable mass is suspended from the hull platform.
Type:
Application
Filed:
November 8, 2016
Publication date:
February 23, 2017
Applicant:
University of Maine System Board of Trustees
Inventors:
Habib J. Dagher, Anthony M. Viselli, Andrew J. Goupee
Abstract: Methods, media, and systems for securing communications between a first node and a second node are provided. In some embodiments, methods for securing communication between a first node and a second node are provided. The methods comprising: receiving at least one model of behavior of the second node at the first node; and authorizing the first node to receive traffic from the second node based on the difference between the at least one model of behavior of the second node and at least one model of behavior of the first node.
Type:
Application
Filed:
July 27, 2016
Publication date:
February 23, 2017
Applicant:
The Trustees of Columbia University in the City of New York
Inventors:
Salvatore J. Stolfo, Gabriela F. Ciocarlie, Vanessa Frias-Martinez, Janak Parekh, Angelos D. Keromytis, Joseph Sherrick
Abstract: Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack.
Type:
Grant
Filed:
July 21, 2014
Date of Patent:
February 21, 2017
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Salvatore J. Stolfo, Wei-Jen Li, Angelos D. Keromytis, Elli Androulaki
Abstract: Compressive sensing based video rate imaging techniques are presented. Rather than scan the entire image, the imaging system only scans part of the topography of the sample as a compressed scan. After the data has been collected, an algorithm for image reconstruction is applied for recovering the image. Because compressive sensing is used, the imaging rate is increased from several minutes per frame to seconds per frame. Non-vector space control techniques are also presented. No-vector space control use image or compressive data as the input and feedback to generate a closed-loop motion control. Compressive sensing technique provides an efficient data reduction method to retain the essential information in the original image. The non-vector space control method can be used as motion control method with compressive feedback without or with noise.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
February 21, 2017
Assignee:
Board of Trustees of Michigan State University
Inventors:
Ning Xi, Bo Song, Jianguo Zhao, Wai Chiu King Lai
Abstract: A visual function evaluation is performed using a sequence of interactions with a mobile device. A patient user may perform a variety of visual tests using the mobile device. The mobile device transmits the test results to a remote server implementing analysis of the visual function results using network service. The network service receives the test results, processes the results, and provides the processed results to a healthcare provider. The processed results may include trends of the user's visual function test performance. The healthcare provider, such as a physician, may optimize and administer treatment based on the data. Early detection of changes in visual function can enable the healthcare provider to individualize treatment, helping to prevent vision loss while minimizing visits to the office, discomfort, and expense.
Type:
Grant
Filed:
April 4, 2016
Date of Patent:
February 21, 2017
Assignee:
The Board of Trustees of the Leland Stanford Junior University