Patents Assigned to Trustee
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Patent number: 8340519Abstract: A passive optical network is disclosed that enables burst mode operation without some of the disadvantages for doing so in the prior art. An embodiment of the present invention comprises a receiver that receives optical signals from transmitters of a plurality of optical network units. For each transmission from an optical network unit, the receiver provides an output signal based on a comparison of the optical signal and a reference voltage that is specific to that optical network unit. A digital-to-analog converter generates the reference voltage in a data rate-independent manner based on information provided to it from the control plane.Type: GrantFiled: May 19, 2008Date of Patent: December 25, 2012Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Jaedon Kim, Jin-Woo Cho, Leonid G. Kazovsky
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Patent number: 8339897Abstract: Slowness dispersion characteristics of multiple possibly interfering signals in broadband acoustic waves as received by an array of two or more sensors are extracted without using a physical model. The problem of dispersion extraction is mapped to the problem of reconstructing signals having a sparse representation in an appropriately chosen over-complete dictionary of basis elements. A sparsity penalized signal reconstruction algorithm is described where the sparsity constraints are implemented by imposing a l1 norm type penalty. The candidate modes that are extracted are consolidated by means of a clustering algorithm to extract phase and group slowness estimates at a number of frequencies which are then used to reconstruct the desired dispersion curves. These estimates can be further refined by building time domain propagators when signals are known to be time compact, such as by using the continuous wavelet transform.Type: GrantFiled: December 22, 2009Date of Patent: December 25, 2012Assignees: Schlumberger Technology Corporation, Trustees of Boston UniversityInventors: Shuchin Aeron, Sandip Bose, Henri-Pierre Valero, Venkatesh Saligrama
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Patent number: 8338601Abstract: A method of performing a chemical reaction includes reacting a compound selected from the group consisting of an organohalide and an organo-pseudohalide, and a protected organoboronic acid represented by formula (I) in a reaction mixture: R1—B-T??(I); where R1 represents an organic group, T represents a conformationally rigid protecting group, and B represents boron having sp3 hybridization. When unprotected, the corresponding organoboronic acid is unstable by the boronic acid neat stability test. The reaction mixture further includes a base having a pKB of at least 1 and a palladium catalyst. The method further includes forming a cross-coupled product in the reaction mixture.Type: GrantFiled: September 25, 2009Date of Patent: December 25, 2012Assignee: Board of Trustees of the University of IllinoisInventors: Martin D. Burke, David M. Knapp, Eric P Gillis
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Patent number: 8341068Abstract: The present invention discloses a method and apparatus for generating and evaluating ideas within an organization through an idea market. It includes an automatic price-setting mechanism that modifies the share-price at the same instant that a trade is made, yet without the assistance of a market maker or a queue of orders. The instant price-setting is achieved by assuming a pre-defined relationship between the quantity of shares in the order and the average share price for that order. This relationship is the price-quantity function. The present invention also includes a mechanism of weighted parameters to modify the share-price in addition to pure supply and demand. The parameters can be adjusted over time in a neural network to optimize the relationship between the share price and the prediction of the actual idea value.Type: GrantFiled: December 15, 2008Date of Patent: December 25, 2012Assignee: The Trustees of the Stevens Institute of TechnologyInventors: Peter Koen, Gerrit Kamp
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Patent number: 8337909Abstract: A process of extracting procyanidins by alkaline hydrolysis. In particular, a procyanidin-containing material, pomace or residue is treated with an alkali, such as sodium or potassium hydroxide, for a predetermined amount of time and at a predetermined temperature to release procyanidins bound to polysaccharides and/or proteins of the cell wall or depolymerize polymeric procyanidins. After the procyanidins are released by alkaline hydrolysis, the extracts are acidified to obtain a pH level where the procyanidins do not degrade. The process of extracting procyanidins may be utilized to estimate the total amount of bound procyanidins in a plant material, enhance the bioavailability of beneficial procyanidins monomers and/or to treat the residue remaining after conventional solvent extraction for increased procyanidin extraction.Type: GrantFiled: June 4, 2010Date of Patent: December 25, 2012Assignee: Board of Trustees of the University of ArkansasInventors: Luke R. Howard, Brittany L. White, Ronald L. Prior
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Patent number: 8338111Abstract: The present invention relates to methods for determining a risk or identifying a condition associated with the presence of endometriosis in a subject as well as testing a candidate compound for a therapeutic activity for the treatment of endometriosis and sorting patients based on the risk of having endometriosis. Specifically, the methods utilize novel markers for assessing the risk of the patient having endometriosis.Type: GrantFiled: April 26, 2011Date of Patent: December 25, 2012Assignee: The Trustees Of The University Of PennsylvaniaInventors: Kurt T. Barnhart, Beata Seeber, George L. Gerton, Mary D. Sammel
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Patent number: 8341097Abstract: Circuits, devices and methods for processing learning networks are implemented using a variety of methods and devices. One example involves a circuit-implemented method to identify a relationship of objects in a set of objects. Local scores are generated for the object and possible parents. The local scores indicate relationship strength between object and parent. The results are stored in a memory. A state-machine circuit is used to perform sampling and searching of the parent sets for each data node. The local scores are used to encode orderings of the parent. An algorithm is executed that uses the encoded possible orderings and a random variable to generate and score a current order and a proposed order of the possible parent sets. The proposed orders are accepted or rejected based on probability rules applied to the scores for the current and proposed orders. Structures are sampled to assess a Bayesian-based relationship.Type: GrantFiled: January 29, 2010Date of Patent: December 25, 2012Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Teresa H. Meng, Wing H. Wong, Narges Asadi Bani
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Patent number: 8337941Abstract: The present invention relates to compounds of the general structure: wherein Y is O, X is O, bond ? is absent and bond ? is present, or Y is H, X is CH, bond ? is present, and bond ? is absent; atom Z is a carbon and bonds ?, ? and ? are present, or is a nitrogen and bonds ?, ? and ? are absent; R1 is —H, —OH, —O—R7, —N(H)—R8, —N(H)—(CH2)n—NH2, —N(R9)(R10), or a piperazine cation; R2 is either covalently bound to R9, or is —H, or is covalently bound to R3 so as to form a substituted or unsubstituted pyrrole or R2 is covalently bound to R9 or R8 or R7; or R1 and R2 are covalently joined to form an aromatic ring; R3 is either covalently bound to R2 so as to form a pyrrole, or is, inter alia, —H, —OH, alkyl, or when Z is nitrogen R3 is ?O; R4 is, inter alia, —H, —OH, or —R11NH2; R5 is, inter alia, —H, —OH, or —R12NH2, and R6 is either is covalently bound to R10 or is —H, or R6 is covalently bound to R10 or R8 or R7.Type: GrantFiled: July 27, 2007Date of Patent: December 25, 2012Assignee: The Trustees of Columbia University in the City of New YorkInventors: Niko Gert Gubernator, Dalibor Sames, David Sulzer, Paul Vadola
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Patent number: 8337873Abstract: This invention relates to the synthesis of new tooth or bone from an encapsulated biological agent such as a growth factor or stem cells contained within a hollow and porous biocompatible vehicle such as a titanium implant placed (implanted) within the body of a host animal such as a human.Type: GrantFiled: October 20, 2005Date of Patent: December 25, 2012Assignee: The Board of Trustees of the University of IllinoisInventor: Jeremy Jian Mao
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Patent number: 8337387Abstract: Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans.Type: GrantFiled: November 22, 2011Date of Patent: December 25, 2012Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Connie C. Wong, Kevin E. Loewke, Thomas M. Baer, Renee A. Reijo-Pera, Barry Behr
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Patent number: 8338492Abstract: Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.Type: GrantFiled: June 18, 2010Date of Patent: December 25, 2012Assignees: The Trustees of the Boston University, The Brigham and Women's Hospital, Inc.Inventors: Yolonda L. Colson, Solomon Azouz, Mark W. Grinstaff, Jesse Wolinsky, Aaron Griset
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Patent number: 8338176Abstract: Provided is a method for the derivation of neural stem cells (NSCs) from embryonic stem cells (ESCs) and the use of the NSCs for treatment of various neural disorders. The NSCs that are derived from the ESCs are tissue-specific multipotent NSCs with a stable growth rate, unlimited self-renewal capacity, and a predictable differentiation profile. Being both non-tumorigenic and engraftable, the NSCs of the present invention have utility in repopulation stroke-damaged tissue. The NSCs of the present invention may be differentiated to produce tyrosine-hydroxylase expressing neurons, which may be used as a source of dopaminergic neurons for subjects suffering from a condition characterized by dopaminergic dysfunction, such as Parkinson's disease.Type: GrantFiled: July 29, 2008Date of Patent: December 25, 2012Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Marcel M. Daadi, Gary K. Steinberg
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Patent number: 8337951Abstract: Certain aspects of the present disclosure are directed to a method of forming a superhydrophobic surface. The method includes: preparing a surface of a substrate of a first material; modifying the surface through an etching process to generate a plurality of nucleation sites in an array; forming, by using glancing angle deposition, a plurality of nano-rods of a second material and each at a respective one of the plurality of nucleation sites in the array; and depositing a conformal coating on the plurality of nano-rods.Type: GrantFiled: April 5, 2010Date of Patent: December 25, 2012Assignee: Board of Trustees of the University of ArkansasInventors: Alexandru S. Biris, Ganesh K. Kannarpady
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Patent number: 8339597Abstract: A label-free multiplexed sensing platform is based on light interaction with aperiodic photonic structures with an advantage of a broadband operation. Multiple-scattering-induced “fingerprinting” colorimetric signatures can be used as a transduction mechanism. Aperiodic sensing platforms can operate in the infrared to provide an overlap with spectral fingerprints of biological molecules. Miniaturized optical biosensors may be based on engineered colorimetric scattering signatures (structural color), sharp spectral features, non-uniform angular distributions of scattered light, and broadband manipulation of the local density of states in nano-textured scattering surfaces with deterministic aperiodic order. The biosensors can be fabricated in semiconductor, metal, low- and high-index dielectric platforms using standard nanofabrication techniques such as electron-beam lithography, ion-beam milling, etc, and can be replicated over large areas by standard nano-imprint lithography.Type: GrantFiled: July 28, 2011Date of Patent: December 25, 2012Assignee: Trustees of Boston UniversityInventors: Luca Dal Negro, Svetlana V. Boriskina, Fiorenzo Omenetto
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Publication number: 20120324408Abstract: A chip generator according to an embodiment of the present invention codifies designer knowledge and design trade-offs into a template that can be used to create many different chips. Like reconfigurable designs, an embodiment of the present invention fixes the top level system architecture, amortizes software and validation and design costs, and enables a rich system simulation environment for application developers. Meanwhile, below the top level, the developer can “program” the individual inner components of the architecture. Unlike reconfigurable chips, a chip generator according to an embodiment of the present invention, compiles the program to create a customized chip. This compilation process occurs at elaboration time—long before silicon is fabricated. The result is a framework that enables more customization of the generated chip at the architectural level because additional components and logic can be added if the customization process requires it.Type: ApplicationFiled: February 17, 2012Publication date: December 20, 2012Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Ofer Shacham, Mark Horowitz, Stephen Richardson
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Publication number: 20120319329Abstract: Self-assembled buckling patterns of thin films on compliant substrates can be used in micro-fabrication. However, most previous work has been limited to planar substrates, and buckling of films on curved substrates has not been widely explored. With the constraining effect from various types of substrate curvature, numerous new types of buckling morphologies can be derived. The morphologies not only enable true three-dimensional (3D) fabrication of microstructures and microdevices, but also can have important implications for the morphogenesis of quite a few natural and biological systems.Type: ApplicationFiled: April 20, 2012Publication date: December 20, 2012Applicant: The Trustees of Columbia University in the City of New YorkInventor: Xi Chen
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Publication number: 20120323112Abstract: Embodiments of the present disclosure provide for nanoparticles for acoustic imaging, methods of using the nanoparticles, methods of imaging a condition, and the like. Embodiments of the present disclosure include nanoparticles (e.g., silica nanoparticles) that can be used to image, detect, study, monitor, evaluate, and/or screen a sample or subject (e.g., whole-body or a portion thereof).Type: ApplicationFiled: June 13, 2012Publication date: December 20, 2012Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Jesse Jokerst, Sanjiv S. Gambhir
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Publication number: 20120321623Abstract: This invention provides a first polypeptide comprising all or a portion of the extracellular domain of ILT3, wherein the polypeptide is water-soluble and does not comprise the Fc portion of an immunoglobulin. This invention also provides a second polypeptide comprising (i) all or a portion of the extracellular domain of ILT3 operable affixed to (ii) the Fc portion of an immunoglobulin, wherein the Fc portion of the immunoglobulin comprises a function-enhancing mutation, and wherein the polypeptide is water-soluble. This invention further provides a third polypeptide comprising (i) all or a portion of the extracellular domain of ILT3 operable affixed to (ii) a transmembrane domain. This invention further provides related nucleic acids, expression vectors, host vector systems, compositions, and articles of manufacture and therapeutic and prophylactic methods using the polypeptides of the invention.Type: ApplicationFiled: May 24, 2012Publication date: December 20, 2012Applicant: The Trustees Of Columbia University In The City Of New YorkInventors: Nicole Suciu-Foca, Luigi Scotto, Seunghee Kim-Schulze, George Vlad, Raffaello Cortesini
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Publication number: 20120322387Abstract: A system for measuring power consumption by a mobile device corresponding to access of web pages is provided. The system includes: the mobile device, configured to access web pages via a wireless network; a power measurement device connected to a battery of the mobile device, configured to measure parameters related to power consumption; and a server, in communication with the mobile device and the power measurement device, configured to control the mobile device's access of web pages and control the power measurement device's measurement of parameters, to receive measurements from the power measurement device, and to process the received measurements so as to correlate the mobile device's access of a web page with an amount of power consumed corresponding to the mobile device's access of the web page.Type: ApplicationFiled: June 15, 2012Publication date: December 20, 2012Applicants: The Board of Trustees of the Leland Stanford Junior University, DEUTSCHE TELEKOM AGInventors: Angela Nicoara, Narendan Thiagarajan, Gaurav Aggarwal, Dan Boneh
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Publication number: 20120318988Abstract: A method for extracting photon depth of interaction information in a positron emission tomography system is provided. A pulse is detected in a photodetector. A height of the pulse is measured. A determination of whether the pulse height is within a set range is made. Photon depth of interaction is extracted from the pulse height. An energy of interaction is calculated from the pulse height and calibration data. The extracted photon depth and calculated energy spectrum are used in image reconstruction.Type: ApplicationFiled: June 14, 2012Publication date: December 20, 2012Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Farhad Taghibakhsh, Craig Steven Levin