Abstract: The system and method for virtual navigation of a sound field through interpolation of the signals from an array of microphone assemblies utilizes an array of two or more higher-order Ambisonics (HOA) microphone assemblies, which measure spherical harmonic coefficients (SHCs) of the sound field from spatially-distinct vantage points, to estimate the SHCs at an intermediate listening position. First, sound sources near to the microphone assemblies are detected and located. Simultaneously, the desired listening position is received. Only the microphone assemblies that are nearer to said desired listening position than to any near sources are considered valid for interpolation. The SHCs from these valid microphone assemblies are then interpolated using a combination of weighted averaging and linear translation filters. The result is an estimate of the SHCs that would have been captured by a HOA microphone assembly placed in the original sound field at the desired listening position.

Abstract: Methods, systems, and computer-readable media for measuring packet delays are provided. An input port of a network device is tapped to duplicate an input packet stream having a first packet. An output port of the network device is tapped to duplicate an output packet stream including the first packet. The duplicated input packet stream and the duplicated output packet stream is transmitted to a programmable device. The first packet in the first input packet stream is matched to the first packet in the first output packet stream. An arrival time and a departure time for the first packet is measured. The difference between the departure time of the first packet and the arrival time of the first packet is determined and the value is reported to an external collector.

Abstract: Methods of inducing or controlling particle motion in suspensions and colloids are described. In one aspect, a method of inducing particle motion in a suspension comprises contacting the suspension with a gas phase to establish at least one interface between the gas phase and continuous phase of the suspension. One or more gases of the gas phase are transferred across the interface to provide a solute gradient in the continuous phase, the solute gradient inducing motion of the suspended particles.

Abstract: In the present invention, a mass and heat exchange system and method are disclosed, wherein water is preferentially absorbed by a non-toxic, non-corrosive liquid desiccant after passing through a hydrophilic, non-porous membrane, and embodiments wherein mixing stages are provided to reduce the surface concentration of water at the desiccant-membrane interface are also provided.

Abstract: A method is disclosed for coating and patterning hydrogels in order to modify surface properties. The method exploits the water content of the hydrogel and the hydrophobicity of the reaction solvent to create a thin oxide adhesion layer on the hydrogel surface. This oxide adhesion layer enables rapid transformation of the hydrophilic, cell non-adhesive hydrogel into either a highly hydrophobic or a cell-adhesive hydrogel by reaction with an alkylphosphonic acid or an ?,?-diphosphonoalkane, respectively. Also disclosed are coated, patterned hydrogels and constructs comprising the coated, patterned hydrogels.

Abstract: According to various embodiments, a method for generating an optimal hidden-layer long short-term memory (H-LSTM) architecture is disclosed. The H-LSTM architecture includes a memory cell and a plurality of deep neural network (DNN) control gates enhanced with hidden layers. The method includes providing an initial seed H-LSTM architecture, training the initial seed H-LSTM architecture by growing one or more connections based on gradient information and iteratively pruning one or more connections based on magnitude information, and terminating the iterative pruning when training cannot achieve a predefined accuracy threshold.

Abstract: An adaptive cognitive prosthetic that learns to replace neural function that was lost due to a brain injury or disease is described herein. In some embodiments, an adaptive cognitive prosthetic comprises a processing unit for converting input data from an input assembly into a cognitive variable and selecting a stimulation pattern for conveying the cognitive variable. The processing unit employs an adaptive algorithm to assemble the stimulation pattern by combination of subset stimulation patterns, the combination of subset stimulation patterns learned by the adaptive algorithm through error analysis.

Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.

Abstract: A method for making a fuel includes reacting a conjugated diene or a mixture of conjugated dienes with a catalyst selected from the group consisting of a low valent iron catalyst stabilized with a pyridineimine ligand, an iron precatalyst coordinated to the pyridineimine ligand that is activated with a reducing agent, a low oxidation state Fe complex stabilized with a pyridineimine ligand and a coordinating ligand, and combinations thereof, thereby forming a substituted cyclooctadiene. The substituted cyclooctadiene is then hydrogenated, thereby forming cyclooctane fuel.

Abstract: In one aspect, phosphine compounds comprising three adamantyl moieties (PAd3) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAd3 ligands are also provided for catalytic synthesis including catalytic cross-coupling reactions.

Abstract: According to various embodiments, a system for accessing video content is disclosed. The system includes one or processors on a video hosting platform for hosting the video content, where the processors are configured to generate an automated transcription of the video content and apply text clustering modules based on a trained neural network to segment the video content.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticaccaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: Described herein are microfluidic devices and methods that can separate and concentrate particles in a sample.

Abstract: Scalable quantum dot devices and methods are described. An example quantum dot device may comprise one or more repeated cells of a repeating quantum dot structure. The repeated cells may be arranged as a linear array of quantum dots. A single repeated cell may comprise a plurality of quantum dots. The repeated cells may be configured to cause movement of a single electron between adjacent quantum dots. A repeated cell may also comprise a charge sensor for readout of the plurality of quantum dots.

Abstract: Occupancy detection is an increasingly important part of building control logic, as new systems and control logic greatly benefit from human-in-the-loop sensing. Current approaches such as CO2 monitoring, acoustic detection, and PIR based motion detection are limited in scope, as these variables are a proxy for occupancy, and at best can be roughly correlated to occupancy, and cannot reliably provide a count of the number of occupants. The disclosed sensor uses thermal information that is continually being emitted by human occupants and optical processing to count and spatially resolve the location of occupants in a room, allowing ventilation flow rates to be properly controlled and directed, if enabled. Occupant detection and counting cheaply and reliably without moving parts is the holy grail of building controls at the moment, which are the basic design principles behind the disclosed inexpensive, static, and stable thermographic occupancy detection sensor.

Abstract: This disclosure provides a system and method for producing ultrasound images based on Full Waveform Inversion (FWI). The system captures acoustic/(an)elastic waves transmitted through and reflected and/or diffracted from a medium. The system performs an FWI process in a time domain in conjunction with an accurate wave propagation solver. The system produces 3D maps of physical parameters that control wave propagation, such as shear and compressional wavespeeds, mass density, attenuation, Poisson's ratio, bulk and shear moduli, impedance, and even the fourth-order elastic tensor containing up to 21 independent parameters, which are of significant diagnostic value, e.g., for medical imaging and non-destructive testing.

Abstract: Processes to identify variants that affect biochemical regulation are described. Generally, models are used to identify variants that affect biochemical regulation, which can be used in several downstream applications. A pathogenicity of identified variants is also determined in some instances, which can also be used in several. Various methods further develop research tools, perform diagnostics, and treat individuals based on identified variants.

Abstract: In one aspect, methods of preparing composite nanoparticle compositions are described herein. For example, in some embodiments, a method comprises providing a zein solution stream, an organic fluid stream including at least one additive and at least one buffer fluid stream. The zein solution stream, organic fluid stream and buffer fluid stream are delivered to a chamber for mixing at one or more rates sufficient to flash precipitate composite nanoparticles including the additive encapsulated by a shell comprising the zein.

Abstract: Provided herein is a system and method of optogenetically inducibly clustering metabolic enzymes for the production of chemicals using cell factories. More particularly, the described inducible protein clustering approach clusters metabolic enzymes by, e.g., a change in illumination conditions (either a switch from dark to light or from light to dark). Performing this clustering leads to an increase in the production of metabolites by the clustered enzymes. In some embodiments, a light-sensitive domain may be replaced with any inducible domain.

Abstract: The disclosure provides compounds of Formulae (I)-(IX). The disclosed compounds are capable of inhibiting a mammalian SHMT. Compounds of the disclosure have numerous uses, such as for treatment of cancer or autoimmune disorders.