Abstract: Methods of preparing fluorinated compounds by carboxylative fluorination using fluoride are contained herein. Fluorinated compounds are provided. Methods of using fluorinated compounds are contained herein.

Abstract: When one looks at a face, one cannot help but ‘read’ it: in the blink of an eye, people form reliable impressions of both transient psychological states (e.g., happiness) and stable character traits (e.g., trustworthiness). Such impressions are irresistible, formed with high levels of consensus, and important for social decisions. Disclosed herein is a large-scale data-driven methodology that allows for the easy manipulation of social trait information in hyper-realistic face images. For example, a given face image could be made to look more or less trustworthy by moving a simple slider. Further, this method can not only generate faces, but can ‘read’ faces as well, providing confidence estimates of different social traits for any arbitrary image. The disclosed approach is both fast and accurate, and represents a paradigm shift in facial photo manipulation.

Abstract: The majority of clinically used antibiotics and anticancer agents are derived from bacterial small molecules. These molecules are produced by dedicated biosynthetic gene clusters, sets of genes that are responsible for the step-wise generation of the target small molecule. Recent investigations have indicated, to the surprise of many experts, that the majority of these biosynthetic genes are inactive or ‘silent’ for unknown reasons. Thus under typical bacterial culturing conditions, these genes are not expressed and consequently the bioactive small molecule products are not synthesized. Disclosed is a method for high throughput screening of elicitors of cryptic metabolites, a method for producing cryptic metabolites, and a new family of cryptic metabolites, the acybolins, as well as their complete structural elucidation.

Abstract: According to various embodiments, a system for vehicular application development is disclosed. The system includes a programmable on-board diagnostics (OBD)-connected dongle for providing computational and storage resources to a vehicle and hosting one or more applications in the vehicle. The dongle is configured to utilize one or more external devices, cloud servers, and add-on modules to provide additional resources for the applications and enable control of the applications. The dongle is implemented with a middleware that enables intended operations of the dongle.

Abstract: A method and system for mass and heat exchange, where water is preferentially absorbed by a non-toxic, non-corrosive liquid desiccant after passing through a hydrophilic, non-porous membrane. Optionally, mixing stages are provided to reduce the surface concentration of water at the desiccant-membrane interface.

Abstract: Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticcacaulis excentricus, and methods of making and using same. Astexin-1 is highly polar, in contrast to many lasso peptides that are primarily hydrophobic, and has modest antimicrobial activity against Caulobacter crescentus, a bacterium related to Asticcacaulis excentricus. The solution structure of astexin-1 was determined, revealing a unique topology that is stabilized by hydrogen bonding between segments of the peptide. Astexins-2 and -3 are intracellular lasso peptides.

Abstract: A method for the electrohydrodynamic deposition of carbonaceous materials utilizing an electrohydrodynamic cell comprising two electrodes comprised of a conductive material, by first combining a solid phase comprising a carbonaceous material and a suspension medium, placing the suspension between the electrodes, applying an electric field in a first direction, varying the intensity of the electric field sufficiently to drive lateral movement, increasing the electrical field to stop the lateral transport and fix the layers in place, then removing the applied field and removing the electrodes. Among the many different possibilities contemplated, the method may advantageously utilize: varying the spacing between the electrodes; removing the buildup from one or both electrodes; placing the electrodes into different suspensions; adjusting the concentration, pH, or temperature of the suspension(s); and varying the direction, intensity or duration of the electric fields.

Abstract: According to some embodiments, a system for widening and densifying a scrape-off layer (SOL) in a field reversed configuration (FRC) fusion reactor is disclosed. The system includes a gas box at one end of the reactor including a gas inlet system and walls of suitable heat bearing materials. The system further includes an exit orifice adjoining the gas box, wherein the exit orifice has a controllable radius and length to allow plasma to flow out from the gas box to populate the SOL with the plasma. The system may also include fusion products, which decrease in speed in the plasma in the SOL, allowing energy to be extracted and converted into thrust or electrical power and further allowing ash to be extracted to reduce neutron emissions and maintain high, steady-state fusion power.

Abstract: The present application provides a method of analyzing protein binding sequence, a method of making sequencing library, and compositions for performing such methods, which employs a transposome complex.

Abstract: Embodiments generally disclosed herein relate to a sub-wavelength multi-port codesign approach between the unit transceiver element and the integrated EM interface to enable a generalized broadband MIMO array with individually programmable element patterns. The co-design approach allows processing of radiated signals at the antenna level distinct from classical arrays. The transmitter and receiver architectures with the integrated EM interface are implemented in 65-nm CMOS and have a bandwidth of 37-73 GHz. Wireless links with data rates up to 12 Gb/s are demonstrated across the spectrum with a wide range of reconfigurability of the active EM interface. The multifunctional EM interface and the broadband transceivers can enable future efficient and compact MIMO arrays for reliable links exploiting frequency, spatial, pattern and polarization diversities.

Abstract: The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses.

Abstract: According to some embodiments, a system for widening and densifying a scrape-off layer (SOL) in a field reversed configuration (FRC) fusion reactor is disclosed. The system includes a gas box at one end of the reactor including a gas inlet system and walls of suitable heat bearing materials. The system further includes an exit orifice adjoining the gas box, wherein the exit orifice has a controllable radius and length to allow plasma to flow out from the gas box to populate the SOL with the plasma. The system may also include fusion products, which decrease in speed in the plasma in the SOL, allowing energy to be extracted and converted into thrust or electrical power and further allowing ash to be extracted to reduce neutron emissions and maintain high, steady-state fusion power.

Abstract: The present disclosure generally relates to genetic engineering of bacteria. More particularly, the present disclosure describes genetic engineering of E. coli to create mutant O-antigen ligase, as well as novel lipopolysaccharide molecules resulting from that genetic engineering. Methods for using those novel molecules are also described.

Abstract: Disclosed is a method and apparatus relating generally to scalar atomic magnetometers. The disclosed methods and apparatus utilize a pressurized sample chamber and a high frequency pulsed pump laser to increase spin polarization and significantly suppress heading errors. These methods and apparatus may also include alternating polarization of the pump light between pulses.

Abstract: A weak binary classifier configured to receive an input signal for classification and generate a classification output is disclosed. The weak binary classifier includes a plurality of weighting amplifier stages, each weighting amplifier stage being configured to receive the input signal for classification and a weighting input derived from a classifier model and generate a weighted input signal, the plurality of weighting amplifier stages being configured to generate a plurality of positive weighted input signals coupled to a positive summing node and a plurality of negative weighted input signals coupled to a negative summing node. The weak binary classifier also includes a comparator having a non-inverting input coupled to the positive summing node and an inverting input coupled to the negative summing node and being configured to generate a weak classification output based on the plurality of weighted input signals.

Abstract: A method is provided for measuring at least two flow properties of a fluid. The method includes providing at least two nanowires, the resistance of each nanowire varying based on a value of a different respective flow property such that each nanowire is configured to measure the different respective flow property, and operating each of the nanowires in a different respective mode of operation, in order to measure the at least two flow properties simultaneously in real-time. Other embodiments are also described.

Abstract: Agents and methods of inhibiting or improving the growth of viruses are provided.

Abstract: According to various embodiments, a system for accessing video content is disclosed. The system includes one or processors on a video hosting platform for hosting the video content, where the processors are configured to generate an automated transcription of the video content and apply text clustering modules based on a trained neural network to segment the video content.

Abstract: A system and method for fueling a fusion reactor. The system includes a reactor chamber containing a stable plasma including a fusion fuel; a heating system configured to heat the plasma and increase an ion energy of the plasma to a level sufficient for producing net power from fusion reactions in the stable plasma; a plurality of magnets coaxial to the reactor chamber, the plurality of magnets producing a magnetic field sufficient to confine the stable plasma and promote rapid loss of fusion products into a scrape off layer; and a neutral beam injection system configured to inject additional quantities of the fusion fuel to sustain the power output of the fusion reaction.

Abstract: According to various embodiments, a method for locating the user of a mobile device without accessing global position system (GPS) data is disclosed. The method includes determining the last location that the user was connected to a wireless network. The method further includes compiling publicly-available auxiliary information related to the last location. The method additionally includes classifying an activity of the user to driving, traveling on a plane, traveling on a train, or walking. The method also includes estimating the location of the user based on sensory and non-sensory data of the mobile device particular to the activity classification of the user.