Abstract: A method of inhibiting viral infection using a monovalent antigen binding protein comprising a single domain binding unit capable of binding to a virus is described. Preferably the protein is a heavy chain variable domain derived from an immunoglobulin naturally devoid of light chains. Food, pharmaceutical and cosmetic products comprising such proteins are also described together with a method for selecting inhibiting proteins from a large population of mainly containing non-inhibiting, but infectious agent binding fragments.

Abstract: New products are provided comprising inactivated lower eukaryotic cells, preferably yeasts or molds, having at the outer surface functionally active antibodies or functionally active fragments thereof. Preferred antibody fragments are the variable domains of Camelidae heavy chain antibodies, which are surprisingly stable against physical and chemical decontamination regimes and do not loose their activity when they are immobilized on the glucan layer of the cell wall which is present in a variety of lower eukaryotes. The new products are preferably in the field of food products, personal care products, and animal feed products.

Abstract: A method for the targeted provision of consumer information comprising the steps of:

Abstract: A kit of parts comprising

Abstract: Blends containing a vegetable fat or a blend of vegetable fats and at least 0.1 wt % of a composition comprising ursolic acid and oleanolic acid in a weight ratio of 1:00 to 99:1 display a number of benefits such as high crystallization rates. This modification of the crystallization rate can be used to achieve a number of beneficial effects in the final fat blend or in the final food product containing the blend.

Abstract: Aerated, ultra low-density cast-dehydrated syndet detergent bars for use in personal wash, fabric wash and hard surface cleaning. A process for preparing aerated, ultra low-density cast-dehydrated detergent bars wherein the air is entrained in the bars after rigidification and shaping the product is also provided.

Abstract: Pinolenic acid can be used in the form of a food supplement, a pharmacentical composition or as part of a food composition as anti-inflammatory agent. The pinolenic acid used herefore suitably is applied as a natural product, or as a concentrate with more than 28 wt % pinolenic acid. The concentrates can be made by a process, wherein an enzymic hydrolysis on a glyceride material is performed.

Abstract: Blends of a natural wax, such as sunflower wax and glyceride materials, substantially being triglycerides and having an N20>20 display excellent properties when applied in barrier layers for compound food products.

Abstract: Blends of glycerides and/or fatty acids comprising 20 to 65 wt % C16:1 fatty acid, balance other fatty acids with 12 to 24 C-atoms and having a C16:1 to C16:0 fatty acid ratio of more than 2.0 and an C16:1 to C18:1 fatty acid ratio of more than 1.2 perform well in food applications. These blends of glycerides can be made by a process involving a partial enzymic hydrolysis of materials derived from fish oil using an enzyme with specificity for C16:1, removal of the fatty acids and a fractionation of the acids.

Abstract: A process for site-directed integration of multiple copies of a gene in a mould is provided, which comprises transforming a mould cell containing in its chromosomal DNA a restriction site for a rare-cutting endonuclease, e.g., I-Scel, preferably introduced at a desired locus, e.g., within a selectable marker gene or in the neighborhood thereof, with a piece of DNA comprising multiple copies of at least one expressible gene comprising at least one structural gene encoding a desired protein, surrounded by two DNA fragments homologous to part of the DNA upstream and downstream, and in the neighborhood, of said restriction site, while during the transformation of the mould the presence of the rare-cutting endonuclease is provided, followed by selecting or screening for a mould cell in which the multiple gene copies of said expressible gene are inserted into the chromosomal DNA of the mould.

Abstract: A reshaped human antibody or reshaped human antibody fragment having specificity for human polymorphic epithelial mucin (PEM) is produced by transferring the complementarity determining regions (CDRs) from a murine anti-HMFG hybridoma cell line HMFG1 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer.

Abstract: The invention describes a process for preparing P zeolites in which aluminate and silicate solutions are reacted in the presence of a P-zeolite seed.

Abstract: Edible fat based flakes containing a flavoring system and displaying an excellent oral and textural properties are disclosed that contain i) 0 to 2% moisture ii) 25 to 90 wt % of a fat containing: a vegetable fat with an N20 of more than 50 and 5 to 40 wt % of a fish oil composition, containing w-3 fatty acids so that the w-3 content of the total flavored fat system ranges from 0.1 to 20 wt % iii) 0 to 15% of a flavoring system iv) 0 to 40% of sugar v) 0 to 60 wt % of a filler vi) 0 to 50% of a health component and which flakes have a size of 0.05 mm to 2.5 cm.

Abstract: An expression library comprising a repertoire of nucleic acid sequences cloned from a non-immunized source, each nucleic acid sequence encoding at least part of a variable domain of a heavy chain derived from an immunoglobulin naturally devoid of light chains (VHH) wherein the extent of sequence variability in the library is enhanced compared to the corresponding naive expression library by introducing mutations in one or more of the complementarity determining regions (CDRs) of the nucleic acid sequences or by generating alternative combinations of CDR and framework sequences not naturally present in the naive library repertoire. Also disclosed is the use of such a library in preparing antibodies, more particularly antibody fragments.

Abstract: Edible compositions containing petroselinic acid are used for the preparation of food compositions or food supplements that are used as anti-inflammatory compositions that inhibit the production of metabolites of arachidonic acid and/or reduces the formation of intracellular adhesion molecules or as anti-aging compositions with a positive impact on wrinkling, sagging, photodamaged skin, dry skin, flaky skin and age spots.

Abstract: Oils, extracted from vegetables and animal tissues contain impurities such as waxes that can be removed in a refining process, including dewaxing of the oils that include removal of oils by filtration through membranes. During filtration, the impurities stick to the membranes, which causes a reduction in flux through the membranes. The initial top flux can be approached again by regularly cleaning the membranes including steps of: backblowing with gas, backflushing with edible oil, and treating the membranes with alkaline material. The cleaning method is particularly suitable for cleaning membranes in the form of microfilters having an average pore diameter of 0.5-5 &mgr;m, which are used in the refining process.

Abstract: An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile in the porous carrier when in the moist state, and an unlabelled specific binding reagent which is permanently immobilised in a detection zone on the carrier material, the labelled and unlabelled specific binding reagents being capable of participating in either a sandwich reaction or a competition reaction in the presence of the analyte, in which prior to the application to the device of a liquid sample suspected of containing the analyte, the labelled specific binding reagent is retained in the dry state in a macroporous body, eg.

Abstract: An ester based lubricant, particularly suitable for 4-stroke engines comprises at least one ester of a saturated, branched chain monohydric alcohol having at least 8 carbon atoms and a saturated branched chain aliphatic monocarboxylic acid having at least 10 carbon atoms. The esters have a kinematic viscosity of at most 35 cSt (40° C.), a non-polarity index of at least 100, a Noack evaporation loss of at most 10% and a pour point below −30° C.

Abstract: In a process for dispensing a powdery product (P) from a container (1) with a dispensing nozzle (4) aimed downwards, a flexible section (3) of the container (1) is deformed at least near the dispensing nozzle (3). This is achieved preferably by a movement of the container relative to the dispensing nozzle, in a direction with a component at a right angle to the dispensing nozzle. The movement of the container (1) and the dispensing of a portion of product from the dispensing nozzle (4) can take place immediately after one another. The invention also comprises a device for dispensing a powdery product (P), with which the process can be carried out and bridge and tunnel formation in the powdery product is opposed effectively.

Abstract: Olive oil is fortified with oleanolic acid by including olive leaves in the malaxation mash of conventional olive oil pressing in an amount of 5-50 wt. %, based on the weight of the malaxation mash. The invention comprises vegetable oils fortified with a concentrate of oleanolic acid and, optionally, oleuropein. Food products fortified with oleanolic acid containing oils or concentrates according to the invention are also part of the invention.