Abstract: The invention provides a method for obtaining information useful to determine the effect of sun exposure on the skin of an individual, the method comprising the steps of: (a) obtaining genomic DNA from skin cells derived from the individual, wherein the skin cells include epidermal skin cells; and (b) observing cytosine methylation of at least two CpG loci in the genomic DNA selected from the group consisting of: cg02066936 cg16929393 cg05715751 cg21177821 cg05504117 cg00772091 cg06066180 cg00675160 cg00067720 cg02491003 cg24490133 cg05355684 cg19283806 cg23976431 cg00025972 cg07050101 cg10557907 cg25588389 cg24114899 cg22695351 cg24105685 cg13181164 cg04258138 cg13181974 cg24357619 cg17196051 cg27546066 cg01203651 cg09496748 cg00297912 cg19757573 cg03243551 cg10634273 cg23225508 cg10397765 cg02037307 cg15084618 cg25677261 cg10294853 cg19145082 cg12577010 cg24489344 cg08243465 cg04935109 cg19720260 cg16293892 cg16210355 cg03597159 cg26837962 cg18582260 cg10624914 cg12474705 cg04425614 cg15701237 cg09055205 cg

Abstract: The invention provides a method for obtaining information useful to determine the extrinsic age of skin of an individual, the method comprising the steps of: (a) obtaining genomic DNA from skin cells derived from the individual; and (b) observing cytosine methylation of >30 CpG loci in the genomic DNA selected from the group consisting of: cg24756227 cg06036239 cg11530289 cg04659582 cg03445800 cg04941246 cg22264616 cg15902864 cg13672200 cg00530720 cg00866690 cg25034941 cg01246665 cg24393844 cg19058262 cg12051116 cg02000606 cg18263166 cg06900899 cg03819134 cg15596932 cg11359720 cg03195377 cg15382568 cg00092551 cg26169991 cg04194664 cg13984289 cg22032385 cg05482603 cg09851620 cg23621013 cg20710730 cg18716076 cg06142351 cg12177909 cg15394860 cg02707854 cg13062888 cg23518497 cg00394718 cg01544580 cg06635832 cg11994639 cg19974120 cg06299192 cg21497480 cg02947450 cg13836638 cg12732514 cg24641302 cg05705140 cg06531870 cg24902858 cg22797031 cg26134692 cg14847243 cg22827250 cg10549088 cg18366919 cg15971980 cg255879

Abstract: The invention provides a method for obtaining information useful to determine the intrinsic age of skin of an individual, the method comprising the steps of: (a) obtaining genomic DNA from skin cells derived from the individual; and (b) observing cytosine methylation of >30 CpG loci in the genomic DNA selected from the group consisting of: cg19381811 cg19670290 cg15393490 cg01465824 cg04999352 cg09046979 cg10426318 cg09077126 cg24374161 cg14896948 cg14412967 cg16937583 cg17508941 cg24757926 cg03936449 cg17953764 cg00442430 cg06621744 cg08076830 cg06882058 cg25351606 cg02662828 cg20897936 cg07878486 cg21992250 cg06335867 cg15171839 cg09017434 cg04044664 cg20442599 cg15488596 cg10384245 cg23368787 cg07960624 cg08622677 cg13848598 cg02273797 cg22593953 cg23213887 cg20234007 cg26492368 cg06470727 cg13612317 cg09432376 cg12530994 cg05457221 cg04766371 cg03614721 cg22624391 cg27369542 cg18322569 cg27284120 cg21303763 cg05238606 cg16300030 cg00085493 cg11239720 cg23942526 cg10568624 cg07217499 cg03405983 cg255908

Abstract: Nanoemulsions and a method for making the same are described. The nanoemulsions comprise a skin benefit agent in the water phase and they are made from two macroemulsions that have non-identical pH values.

Abstract: Disclosed is a skin care kit comprising (a) a freeze-dried cosmetic composition comprising a cosmetic active, and (b) an aqueous cosmetic composition comprising an acrylic polymeric thickener.

Abstract: The invention is in the field of hard surface cleaning compositions. There is need for compositions that foam copiously during the washing/cleaning stage. However, during the rinse stage, the foam should rinse-off as quickly as possible in minimum number of rinses-cycles so that the process becomes sustainable. Disclosed is an aqueous cleaning composition, having a pH of 6.5 or lower, comprising (i) 3.0 to 25.0% by weight alkyl ethoxy sulphate; (ii) 1.0 to 5.0% by weight amphoteric surfactant; (iii) 0.1 to 1.0% by weight fatty acids being saturated non-hydroxy C8-12 fatty acid and a saturated non-hydroxy C14-18 fatty acid, where ratio of amount of said C8-12 fatty acid to that of said C14-18 fatty acid is from 1:0.1 to 1:10 parts by weight; and (iv) 0.5 to 5% by weight non-ionic surfactant, wherein (iii) and (iv) together an antifoaming system, and wherein amount of non-alkoxylated anionic surfactant in said composition in less than 1.0% by weight.

Abstract: The present invention relates to a composition in the form of an oil-in-water emulsion, containing wheat flour and physically modified starch. The invention also relates to a method for preparation of the composition. The invention further relates to the use of a wheat flour and physically modified starch to reduce syneresis in an oil-in-water emulsion.

Abstract: A food composition in the form of an emulsion comprising a continuous water phase which comprises a water-in-oil emulsion which is emulsified in the continuous water phase, and oil droplets without an internal water phase emulsified in the continuous water phase, polyglycerol polyricinoleate, and an oil-in-water emulsifier.

Abstract: The invention relates to a composition comprising 5 to 100 wt. % of a structured aqueous phase wherein the composition contains 0.1 to 10 wt. % sericin by weight of water, said sericin having a proportion of beta-sheet in the secondary structure that exceeds 80%. It was found that sericin having a proportion of beta-sheet in the secondary structure that exceeds 80% is an excellent water structurant and can suitably be used to structure the aqueous phase of a wide range of products, such as cosmetic products, pharmaceutical products, food products and detergent compositions.

Abstract: The present invention provides an apparatus for coating an edible receptacle the apparatus comprising a nozzle for applying a fat-based coating material to the internal surface of the edible receptacle and a gas-dosing element with an external surface shape corresponding to the internal shape of the edible receptacle wherein the gas dosing element has at least one aperture suitable for the introduction of cooled gas into the edible receptacle.

Abstract: The invention relates to a tag to secure a string of a tea bag to a handle of a teapot, the tag being flexible and resilient and comprising at least two adjacent areas separated by a cut that are partially separable from the tag.

Abstract: Disclosed is a non-spherical microcapsule comprising a core comprising fatty ester having a melting point of at least 30° C. and a benefit agent; a shell comprising nanoparticles having a diameter of 10 to 300 nm.

Abstract: Disclosed is a microcapsule comprising benefit agent and water-insolvable solid particle, wherein the microcapsule has an aspect ratio of from 3:1 to 12:1 and the weight ratio of the particle to the benefit agent is 1:5 to 50:1, where aspect ratio means the ratio of the length to width of the microcapsule as measured by optical microscopy, where length refers to the longest measurable distance of the microcapsule in the optical image and width refers to the longest measurable distance of the microcapsule along the direction perpendicular to the length of the microcapsule in the optical image, and where water-insolvable refers to a material that dissolves in water to give a solution with a concentration of less than 1 gram per litre, wherein, the water-insolvable solid particle comprises a plurality of pores throughout the particles and the benefit is encapsulated inside the pores

Abstract: Disclosed is a packaged frozen confection (1) comprising a flexible pouch (2), wherein the pouch (2) comprises a wall (4) delimiting a cavity containing the frozen confection and extending in a longitudinal direction from a base end (6) to a top end (5) of the pouch. The top end (5) comprises a product outlet (8) through which the frozen confection can be extruded from the cavity. The base end (6) comprises a gusset (7) extending in a transverse direction, the top end (5) comprises a top edge (3) extending in the transverse direction, and the product outlet (8) is disposed at or proximal to a corner of the top edge (3). The wall (4) is deformable at least at the base end (6) of the pouch (2) to urge the frozen confection in the cavity towards the outlet (8) and extrude at least a portion of frozen confection therefrom.

Abstract: The present invention relates to an antimicrobial composition. The present invention provides an antimicrobial composition comprising at least one biphenol and monohydric non-phenolic alcohol in certain amounts. The antimicrobial composition provides synergistic antimicrobial benefit, particularly synergistic antiviral benefit.

Abstract: The present invention relates to a pre-treatment composition for the cleaning of fabrics, especially a sprayable foamable liquid cleaning composition. It is an object of the present invention to provide a sprayable foamable liquid cleaning composition for the pretreatment of fabric which has superior soil removal properties for a wide variety of stains. It is yet another object of the present invention to provide a foamable cleaning composition having a pH of less than 4 which provides good stain removal benefits without compromising on the stability of the isotropic solution or foam structure. We have found that a foamable liquid composition providing a stable foam which exhibits dilutability, homogeneity in solution, excellent cleaning performance on various stain types can be prepared when higher levels of solvents and low pH are combined with specific amounts of alkoxylated anionic surfactant, nonionic surfactant, amphoteric surfactant and at specific ratios between the surfactant and solvents.

Abstract: The invention relates to method of enhancing yield of alkyl taurate amides using enhancing specifically phosphoric acid catalysts. It further relates to the use of phosphoric acid to enhance yield while avoiding and/or reducing undesirable browning.

Abstract: The present invention relates to an antimicrobial composition and more particularly to an antimicrobial composition at the pH of skin. The present invention provides an antimicrobial composition comprising: a. 0.5 to 20% by weight of a solvent comprising an alkyl glycol ether, b. 0.1 to 20% by weight of a carboxylic acid selected from an aromatic carboxylic acid having pKa greater than 4 or an aliphatic carboxylic acid having pKa greater than 4.5 or mixtures thereof c. 1 to 80% by weight of an anionic surfactant.

Abstract: A laundry system for dispensing one or more ingredient compositions from ingredient reservoirs for supplying to a washing machine drum, the laundry system comprising: (i) an apparatus which comprises a dispensing device and multiple ingredient reservoirs; (ii) said multiple ingredient reservoirs comprising a recycled material and containing the various ingredient compositions in controllable fluid communication with the dispensing device and each ingredient reservoir comprising at least one ingredient reservoir identifier; (iii) said dispensing device being operable to selectively dispense portions of the ingredient compositions from respective ingredient reservoirs as a result of commands by the user to provide a dose of laundry product, and further comprising (iv) an ingredient reservoir control system for controlling said selective dispensing of respective ingredient compositions from specific ingredient reservoirs identified by respective ingredient reservoir identifiers such that the device can selective

Abstract: The present invention relates to novel oil-in-water pumpable nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum as well as C8 to C18 fatty acid; and the aqueous phase contains sulfoalkyl ester and/or amide of fatty acids as emulsifier.