Abstract: An improved raster magnet driver for a linear particle beam is based on an H-bridge technique. Four branches of power HEXFETs form a two-by-two switch. Switching the HEXFETs in a predetermined order and at the right frequency produces a triangular current waveform. An H-bridge controller controls switching sequence and timing. The magnetic field of the coil follows the shape of the waveform and thus steers the beam using a triangular rather than a sinusoidal waveform. The system produces a raster pattern having a highly uniform raster density distribution, eliminates target heating from non-uniform raster density distributions, and produces higher levels of beam current.

Abstract: Upon exposure to UVB, the epidermal component trans-urocanic acid is not only photoisomerized into cis-urocanic acid, but will also, at least in part, be photooxidized into urocanic acid oxidation products. We hypothesized that urocanic acid oxidation products can mimic UV-induced systemic immunosuppression comparable to the suppressive properties already established for cis-urocanic acid. A crude mixture of urocanic acid oxidation products showed a significant suppression of the sensitization phase of the systemic contact hypersensitivity response to picryl chloride. Three of the urocanic acid oxidation products were selected for this study: imidazole-4-carboxylic acid, imidazole-4-carboxaldehyde and imidazole-4-acetic acid. Effects on the sensitization-, elicitation- and post-elicitation phase of contact hypersensitivity to picryl chloride in BALB/c mice were studied and compared to the effects of cis-urocanic acid.

Abstract: A method and system for imaging of a scattering target medium using a modified perturbation formulation of a radiation transport equation where normalized measured values are used to recover a relative difference in absorption and/or scattering properties based on the normalized measured values with respect to a reference medium. The modified perturbation formulation provides enhanced stability, reduces the sensitivity of solution to variations between the target and reference media, produces solutions having physical units and reduces the need for absolute detector calibration. Moreover, the modified perturbation equation lends itself to the detection and imaging of dynamic properties of the scattering medium.

Abstract: Disclosed herein is a method for protecting and restoring a link in an OBS network. The method includes a step of transmitting/receiving a liveness-confirming message for confirming liveness of the link between an up-node and a down-node respectively connected to both ends of the link at a predetermined message transmission period, to judge whether a fault is generated on the link, a step in which the up-node and down-node respectively update link information when it is judged that the link fault is not generated, and a step of restoring the link having the fault using predetermined restoration channel information based on an offered load measured when the link is in a normal state when it is judged that the link fault is generated. Accordingly, a link having a problem can be effectively protected and restored in the OBS network.

Abstract: The present invention provides natural or transgenic galactose deficient cells, tissues, organs and animals that have been genetically modified to compensate for the abnormalities in galactose metabolic pathways. The present invention modifies sugar metabolic pathways to to prevent the deleterious accumulation of sugar metabolites in animals, tissues, organs, cells and cell lines that possess natural or transgenic abnormalities in the sugar metabolic pathways. Such cells, tissues, organs and animals can be used in research and medical therapy, including xenotransplantation.

Abstract: The present invention provides novel nucleic acid and protein sequences for methods and compositions for treating, screening, and diagnosing cardiovascular disease and methods for using these genes and gene products for prevention of cardiac cell death and prevention of cardiac tissue damage resulting from ischemic events in cardiac tissue, as well as other tissue that is subject to damage resulting from an ischemic event. The genes, gene products and agents of the invention are also useful for treating other related clinical or coronary events such as angina, myocardial infarct (MI), and stroke, for monitoring the effectiveness of their treatment, and for drug development. The genes, gene products and agents of the present invention are also provided as pharmaceutical compositions for treatment of cardiovascular disease, ischemic heart disease, myocardial infarct and related conditions. Kits are also provided for the diagnosis, treatment and prognosis of cardiac diseases and related conditions.

Abstract: A vacuum system comprising: 1) an ion pump; 2) power supply; 3) a high voltage DC—DC converter drawing power from the power supply and powering the vacuum pump; 4) a feedback network comprising an ammeter circuit including an operational amplifier and a series of relay controlled scaling resistors of different resistance for detecting circuit feedback; 5) an optional power block section intermediate the power supply and the high voltage DC—DC converter; and 6) a microprocessor receiving feedback information from the feedback network, controlling which of the scaling resistors should be in the circuit and manipulating data from the feedback network to provide accurate vacuum measurement to an operator.

Abstract: A controlled radius of curvature mirror assembly comprising: a distortable mirror having a reflective surface and a rear surface; and in descending order from the rear surface; a counter-distortion plate; a flow diverter having a flow diverter aperture at the center thereof; a flow return plate having a flow return aperture at the center thereof; a thermal isolation plate having a thermal isolation plate aperture at the center thereof and a flexible heater having a rear surface and a flexible heater aperture at the center thereof; a double walled tube defining a coolant feed chamber and a coolant return chamber; said coolant feed chamber extending to and through the flow diverter aperture and terminating at the counter-distortion plate and the coolant return chamber extending to and through the thermal isolation backplate and terminating at the flow diverter; and a coolant feed and a coolant return exit at the rear of said flexible heater.

Abstract: A method for controlling the momentum compaction in a beam of charged particles. The method includes a compaction-managed mirror bend achromat (CMMBA) that provides a beamline design that retains the large momentum acceptance of a conventional mirror bend achromat. The CMMBA also provides the ability to tailor the system momentum compaction spectrum as desired for specific applications. The CMMBA enables magnetostatic management of the longitudinal phase space in Energy Recovery Linacs (ERLs) thereby alleviating the need for harmonic linearization of the RF waveform.

Abstract: The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.

Abstract: A cyclopentadienyl ruthenium (II) complex or (iv) complex having an ?-imino acid type ligand or an ?-amino acid type ligand.

Abstract: A single lens laser beam shaper for converting laser beams from any spatial profile to a flat-top or uniform spatial profile. The laser beam shaper includes a lens having two aspheric surfaces. The beam shaper significantly simplifies the overall structure in comparison with conventional 2-element systems and therefore provides great ease in alignment and reduction of cost.

Abstract: The present invention provides compounds and compositions, which include: at least one chromophore having strong simultaneous two-photon or multi-photon absorptivity; at least one acid- or radical-generator in close proximity to the chromophore; such that the single- or multi-photon excitation of the chromophore results in the generation of an acid and/or redical that is capable of activating chemistry; and such that compositions of matter based on the componds and compositions of the invention can be photo-patterned by one- or multiphoton excitation.

Abstract: This invention describes the cloning and characterization of the promoter region for the PCA3dd3 gene. This region regulates the PCA3dd3 gene expression by a unique prostate specific transcriptional mechanism. The present invention relates to the use of this promoter region as a tool for prostate cancer treatment and diagnosis and screening of agents which regulate expression of PCA3. In a particular embodiment, the present invention relates to an isolated promoter sequence which comprises an isolated promoter sequence which comprises a sequence as set forth between nucleotide positions 372 to 460 of SEQ ID NO:1, this sequence enabling a prostate-specific modulation of transcription.

Abstract: The present invention relates to a protein (Snow1), mutants thereof, and nucleic acids encoding said protein, that interacts with Ice1 and which activates CBF3 promoter activity thus regulating freezing tolerance in plants.

Abstract: The present invention is directed to a multi-band cable antenna.

Abstract: The present invention is directed to an internal multi-band antenna with multiple layers. The internal multi-band antenna comprises a main radiation patch for forming an upper side of the antenna, one side of the main radiation patch connected to a feeder, the main radiation patch including a plurality of strips in the same plane and formed by a folded slit patch of maze type; and at least one auxiliary radiation patch bent downwardly at one side of an edge of the main radiation patch and formed in parallel to the main radiation patch between the main radiation patch and a feeder ground plane.

Abstract: A novel particle beam target comprising: a rotating target disc mounted on a retainer and thermally coupled to a first array of spaced-apart parallel plate fins that extend radially inwardly from the retainer and mesh without physical contact with a second array of spaced-apart parallel plate fins that extend radially outwardly from and are thermally coupled to a cooling mechanism capable of removing heat from said second array of spaced-apart fins and located within the first array of spaced-apart parallel fins. Radiant thermal exchange between the two arrays of parallel plate fins provides removal of heat from the rotating disc. A method of cooling the rotating target is also described.

Abstract: A particle beam recirculated chicane geometry that, through the inducement of a pair of 180 degree bends directed by the poles of a pair of controllable magnetic fields allows for variation of dipole position, return loop radii and steering/focussing, thereby allowing the implementation of independent variation of path length and momentum compaction.

Abstract: Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogeneous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.