Patents Assigned to UNIVERSITÉ DE BRETAGNE OCCIDENTALE
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Patent number: 9956262Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.Type: GrantFiled: May 23, 2014Date of Patent: May 1, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE RENNES 1, UNIVERSITE DE BRETAGNE OCCIDENTALEInventors: Florie Desriac, Yannick Fleury, Patrick Le Chevalier, Delphine Destoumieux, Matthieu Simon
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Publication number: 20180051349Abstract: The invention relates to a method for obtaining a superoxide dismutase (SOD)-concentrated protein extract having a specific activity of at least 700 UI/mg protein, said method comprising a single step of extraction from a plant selected from any species of the Plumbaginaceae family.Type: ApplicationFiled: December 28, 2015Publication date: February 22, 2018Applicant: Universite de Bretagne OccidentaleInventors: Christian Magne, Karim Ben Hamed
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Patent number: 9884193Abstract: The invention relates to an active implantable pacemaker. The device analyzes a ventricular electrogram signal (EGM) and is able to recognize, in a search window, an EA4 component of endocardial acceleration (EA) associated with atrial activity. In the presence of atrioventricular conduction, the search window is determined based on the temporal position of the EA1 and/or EA2 components of the EA signal. In the absence of atrioventricular conduction, a delay is counted from a paced ventricular event and applied to mask the EA1 and/or EA2 components in the EA signal, and the window for research of the EA4 component follows the masking delay. In the presence of a confirmed EA4 component, an atrioventricular delay is applied, counted from the EA4 component, and in the opposite case a predetermined escape interval is applied, counted from the last stimulated ventricular event.Type: GrantFiled: October 26, 2015Date of Patent: February 6, 2018Assignees: SORIN CRM SAS, UNIVERSITÉ DE BRETAGNE OCCIDENTALE, CENTRE HOSPITALIER RÉGIONAL ET UNIVERSITAIRE DE BRESTInventors: Amel Amblard, Jérôme Dumont, Fabrizio Renesto, Jacques Mansourati
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Patent number: 9884881Abstract: The invention relates to a chelate resulting from the complexing of a trans-di-N-picolinate tetraazacycloalkane ligand with a metal cation, said ligand corresponding to formula (A) wherein n is equal to 0 or to 1, R is H or a C1-C18 alkyl radical, and R? is H or a C1-C18 alkyl radical, said metal cation being a cation of a metal selected from the group consisting of lead (II) and bismuth (III). The invention is applicable in the field of lead trapping and alpha-radioimmunotherapy.Type: GrantFiled: June 5, 2014Date of Patent: February 6, 2018Assignees: CNRS—Centre National de la Recherche Scientifique, Universite de Bretagne OccidentaleInventors: Raphael Tripier, Carlos Platas-Iglesias, Luis Lima, Maryline Beyler
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Patent number: 9745357Abstract: The invention relates to the A1 peptide of the sequence RRKYGRDFLLRF, as well as to certain variants thereof, for treating cancers, in particular malignant hematopoietic diseases, and more particularly for treating chronic lymphoid leukaemia.Type: GrantFiled: March 5, 2010Date of Patent: August 29, 2017Assignees: Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Brest, Universite de Bretagne Occidentale, Universite Pierre et Marie Curie (Paris 6)Inventors: Bertrand Cosson, Hussam Saad, Patrick Cormier, Christian Berthou, Mirjam Czjzek
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Publication number: 20170031052Abstract: An electromagnetic system for exploring the seabed in a marine environment includes a current injection module with two electrodes spaced apart from one another, said injection electrodes being capable of injecting a current at a predetermined voltage into the marine environment close to the seabed, said injection electrodes having a contact surface with the marine environment. The system includes a data acquisition module with at least two measuring sensors for measuring electrical or magnetic data at least two points of the marine environment close to the seabed, and a power supply module for supplying power to the current injection module. Each electrode includes one or more separate conductive elements that are electrically connected to each other and arranged in such a way as to form a conductive network or a multilayer conductive assembly having a large contact surface with the marine environment.Type: ApplicationFiled: October 13, 2016Publication date: February 2, 2017Applicants: Universite De Bretagne Occidentale - UBO, Centre National de la Recherche Scientifique - CNRSInventors: Jean-Francois D'eu, Pascal Tarits, Fabien Gaspari
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Publication number: 20160193284Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.Type: ApplicationFiled: May 23, 2014Publication date: July 7, 2016Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S), UNIVERSITE DE RENNES 1, UNIVERSITE DE BRETAGNE OCCIDENTALEInventors: Florie DESRIAC, Yannick FLEURY, Patrick LE CHEVALIER, Delphine DESTOUMIEUX, Matthieu SIMON
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Patent number: 9364623Abstract: A method for administering a gas containing oxygen to a patient. The method includes: measuring an oxygen-dependent physiological parameter in the patient; determining an optimal gas delivery parameter based on the oxygen-dependent physiological parameter; and administering the gas to the patient in accordance with the optimal gas delivery parameter. In some embodiment of the invention, the method also includes monitoring the oxygen-dependent physiological parameter.Type: GrantFiled: July 15, 2010Date of Patent: June 14, 2016Assignees: Université Laval, Université de Bretagne OccidentaleInventors: Francois Lellouche, Erwan L'Her
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Patent number: 9315511Abstract: Special C-functionalized cyclic bisaminal compounds having formula (I) or (II), their salts or solvates, methods for their preparation, their uses, and methods for preparing functional tetraazacycloalkane compounds implementing such cyclic bisaminal compounds.Type: GrantFiled: November 16, 2012Date of Patent: April 19, 2016Assignees: UNIVERSITE DE BRETAGNE OCCIDENTALE, CNRS—CENTRE NATIONAL DE LA RECHERCHEInventors: Raphael Tripier, Nathalie Camus
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Patent number: 9216165Abstract: The present invention relates to a combination of (i) a statin, and (ii) a taxane, for simultaneous or sequential use in the treatment of a patient suffering from solid tumor, e.g. a gastric cancer. The present invention also provides a statin, for use in a method for enhancing sensitivity of a patient suffering from a solid tumor to a taxane.Type: GrantFiled: May 10, 2012Date of Patent: December 22, 2015Assignees: INSERM (Institut National de la Sante et de la Recherche Medicale), Universite de Bretagne OccidentaleInventors: Laurent Corcos, Catherine Le Jossic-Corcos
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Patent number: 9161944Abstract: The present invention relates to the use of a specific family of glycerolipid compounds of formula (I) described in the detailed description or the manufacture of a medicament for the prevention or for the treatment of cancer metastasis.Type: GrantFiled: February 17, 2011Date of Patent: October 20, 2015Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE BRETAGNE OCCIDENTALE (U.B.O.), UNIVERSITE FRANCOIS-RABELAIS DE TOURSInventors: Christophe Vandier, Philippe Bougnoux, Aurelle Chantome, Bernard Corbel, Alban Girault, Jean-Pierre Haelters, Virginie Joulin, Marie Potier-Cartereau, Gaelle Simon
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Patent number: 9083381Abstract: A method and apparatus are provided for determining at least one parameter of an error correcting code implemented on transmission, termed a “coding parameter”, by analyzing a binary train received. The method implements a first step making it possible to coarsely define said at least one coding parameter, and a second step making it possible to refine said at least one coding parameter.Type: GrantFiled: July 6, 2011Date of Patent: July 14, 2015Assignee: Universite de Bretagne OccidentaleInventors: Roland Gautier, Eric Rannou, Mélanie Marazin, Gilles Burel
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Publication number: 20150153471Abstract: An electromagnetic system for exploring the seabed in a marine environment includes a current injection module with two electrodes spaced apart from one another, said injection electrodes being capable of injecting a current at a predetermined voltage into the marine environment close to the seabed, said injection electrodes having a contact surface with the marine environment. The system includes a data acquisition module with at least two measuring sensors for measuring electrical or magnetic data at at least two points of the marine environment close to the seabed, and a power supply module for supplying power to the current injection module. Each electrode includes one or more separate conductive elements that are electrically connected to each other and arranged in such a way as to form a conductive network or a multilayer conductive assembly having a large contact surface with the marine environment.Type: ApplicationFiled: January 9, 2013Publication date: June 4, 2015Applicants: UNIVERSITE DE BRETAGNE OCCIDENTALE - UBO, CENTRE NATIONAL DE LA RECHERCHE SCIENTIQUE - CNRSInventors: Jean-François D'eu, Pascal Tarits, Fabien Gaspari
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Publication number: 20140315269Abstract: The present invention relates to a method for producing polyphenol compounds, i.e. phloroglucinol or one of its derivatives, with a polyketide synthase of type III (PKSIII) from a brown marine alga. The invention also relates to recombinant nucleic acids coding for a polyketide synthase of type III (PKSIII) from the brown alga Ectocarpus siliculosus (E. siliculosus), to recombinant vectors comprising these nucleic acids, as well as to host cells comprising these vectors. Finally, the invention relates to a method for preparing of various compounds by means of polyphenol compounds produced according to the aforementioned method.Type: ApplicationFiled: September 26, 2012Publication date: October 23, 2014Applicants: UNIVERSITE DE BRETAGNE OCCIDENTALE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)Inventors: Ludovic Delage, Laurence Meslet-Cladiere, Philippe Potin, Sophie Goulitquer
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Publication number: 20140200269Abstract: The present invention relates to a combination of (i) a statin, and (ii) a taxane, for simultaneous or sequential use in the treatment of a patient suffering from solid tumor, e.g. a gastric cancer. The present invention also provides a statin, for use in a method for enhancing sensitivity of a patient suffering from a solid tumor to a taxane.Type: ApplicationFiled: May 10, 2012Publication date: July 17, 2014Applicants: INSERM (Institut National de la Sante et de la Recherche Medicale), UNIVERSITE DE BRETAGNE OCCIDENTALEInventors: Laurent Corcos, Catherine Le Jossic-Corcos
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Publication number: 20140158124Abstract: A method and system for delivering a gas containing carbon dioxide to a patient are described. The method comprises measuring a physiological parameter of breathing stability in the patient; determining an optimal gas delivery parameter based on the physiological parameter of breathing stability; and delivering the gas to the patient in accordance with the optimal gas delivery parameter.Type: ApplicationFiled: January 12, 2012Publication date: June 12, 2014Applicants: UNIVERSITÉ DE BRETAGNE OCCIDENTALE, UNIVERSITÉ LAVALInventors: Erwan L'her, François Lellouche, Frédéric Series
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Patent number: 8731253Abstract: A system and method are provided for helping implant a hip prosthesis in an individual, which includes an acetabulum intended to be placed in the hip bone of the patient and a femoral part intended to be integrally connected to the femur of the individual. The method includes: obtaining, before the operation, images issued by a device that images a human body and locates a position of images in space. The images are taken in at least three reference positions: standing; recumbent; and sitting. Before the operation, the method determines a pelvis version of the individual in different positions by analyzing the images. During the operation, the method measures a position of the acetabulum with relation to the pelvis of the individual, and simultaneously restores information representative of prosthetic mobility of the hip with relation to each of the reference positions, for a current position of the acetabulum.Type: GrantFiled: June 19, 2009Date of Patent: May 20, 2014Assignee: Universite de Bretagne OccidentaleInventors: Guillaume Dardenne, Eric Stindel, Chafiaa Hamitouche, Christian Roux
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Patent number: 8679500Abstract: The present invention relates to compositions containing antibodies for treating CD5+ HLA-DR+ B OR T cell related diseases such as B or T cell malignances (leukaemia and lymphoma), autoimmune diseases and T cell related diseases as transplantation and graft rejection.Type: GrantFiled: May 14, 2010Date of Patent: March 25, 2014Assignees: Institute National de la Sante et de la Recherche Medicale (INSERM), Universite de Bretagne Occidentale, Centre National de la Recherche Scientifique (CNRS)Inventors: Laurence Boumsell, Christian Berthou, Karine Lester, Severine Loisel, Martine Cerruti
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Publication number: 20130166985Abstract: A method and apparatus are provided for determining at least one parameter of an error correcting code implemented on transmission, termed a “coding parameter”, by analyzing a binary train received. The method implements a first step making it possible to coarsely define said at least one coding parameter, and a second step making it possible to refine said at least one coding parameter.Type: ApplicationFiled: July 6, 2011Publication date: June 27, 2013Applicant: UNIVERSITE DE BRETAGNE OCCIDENTALEInventors: Roland Gautier, Eric Rannou, Mélanie Marazin, Gilles Burel
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Patent number: 8431583Abstract: At least one compound of following formula I: in which: X is C or N, Y is CH3 or OH, and Z is H or CH3, or one of its pharmaceutically acceptable salts, hydrates, esters or isomers, for use in the manufacture of a medicament to treat pathologies in which an imbalance between cell division and apoptosis is involved.Type: GrantFiled: September 12, 2008Date of Patent: April 30, 2013Assignees: Centre National de la Recherche Scientifique, Universite de Rennes 1, Universite Paris Descartes, Universite de Bretagne Occidentale, Centre Hospitalier Universitaire de BrestInventors: Laurent Meijer, Karima Bettayeb, Hervé Galons, Nassima Oumata, Christian Berthou, Karine Lester