Patents Assigned to UNIVERSITÀ DEGLI STUDI DI MILANO
  • Publication number: 20210388666
    Abstract: An insulating glazing having at least two panels made of transparent or semi-transparent material is provided. At least one of these panels is a luminescent solar concentrator.
    Type: Application
    Filed: October 28, 2019
    Publication date: December 16, 2021
    Applicants: UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA, GLASS TO POWER S.P.A.
    Inventors: Francesco MEINARDI, Sergio BROVELLI, Francesco BRUNI, Marina GANDINI
  • Publication number: 20210275555
    Abstract: Oligosaccharides are for use in the treatment of neurodegenerative diseases of the central nervous system, in particular Parkinson's disease, and to pharmaceutical compositions including one or more of the oligosaccharides.
    Type: Application
    Filed: July 11, 2019
    Publication date: September 9, 2021
    Applicant: UNIVERSITA' DEGLI STUDI DI MILANO
    Inventors: Sandro SONNINO, Elena CHIRICOZZI
  • Patent number: 11067555
    Abstract: A detection system (101, 101b) of enteric diseases in animals includes a sensor device (102) having suction (103) for suctioning air from the animals' environment (11, 12). A sensor is (104) configured to determine information about the type and concentration of smelling molecules in the air and further configured to emit a signal representative of the information of smelling molecules. A transmission device (105) is configured to convey the signal representative of smelling molecules. A self-learning processing device (108) is configured to receive and process the signal representative of smelling molecules, and to detect a risk of enteric diseases in the animals associated with the information about the type and concentration of the smelling molecules. A signaling device (111) is configured to report to a user (10) the risk of enteric diseases in the animals, before the enteric diseases arise. A relative method detects enteric diseases in animals.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: July 20, 2021
    Assignee: UNIVERSITA' DEGLI STUDI DI MILANO
    Inventors: Marcella Guarino, Valentina Ferrante, Guido Grilli, Federica Borgonovo, Lorenzo Ferrari, Andrea Giovanni Pastori, Ilaria Fontana, Emanuela Tullo, Paolo Guffanti
  • Patent number: 11041270
    Abstract: Process for the plasma surface treatment under vacuum of a fabric, nonwoven fabric or paper material for obtaining materials to be used for the filtration and separation of two immiscible liquids.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: June 22, 2021
    Assignee: Universita' degli Studi Di Milano-Bicocca
    Inventors: Claudia Riccardi, Stefano Zanini
  • Publication number: 20210052723
    Abstract: The present invention relates to new synthetic molecules with agonist activity of human Toll-like Receptor 4 (TLR4), compositions comprising them and uses thereof for the treatment of diseases in which it is useful to induce or increase an immune response. The compounds have general formula (1), wherein R1 is a saturated C8-C16 aliphatic chain having a =0 on C1, said chain being free from —OH substituents on C3, wherein R2 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3, wherein R3 is a saturated C8-C16 aliphatic chain having a ?O on C1, said chain being free from —OH substituents on C3; wherein R4 is a hydrogen atom (H) or a phosphate group (PO42?).
    Type: Application
    Filed: November 5, 2018
    Publication date: February 25, 2021
    Applicant: UNIVERSITA DEGLI STUDI DI MILANO - BICOCCA
    Inventors: Francesco PERI, Alberto MINOTTI
  • Publication number: 20200362507
    Abstract: Process for the plasma surface treatment under vacuum of a fabric, nonwoven fabric or paper material for obtaining materials to be used for the filtration and separation of two immiscible liquids.
    Type: Application
    Filed: May 3, 2017
    Publication date: November 19, 2020
    Applicant: Universita' degli Studi Di Milano-Bicocca
    Inventors: Claudia Riccardi, Stefano Zanini
  • Publication number: 20200333359
    Abstract: The present disclosure relates to delta-2-tubulin and its use as a biomarker for determining if a subject is at risk of developing peripheral neuropathy or if a subject has developed peripheral neuropathy. The present disclosure further relates to methods for the treatment of peripheral neuropathy in a subject and assays for identifying compounds that can be used to treat and/or prevent peripheral neuropathy.
    Type: Application
    Filed: May 27, 2020
    Publication date: October 22, 2020
    Applicants: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, UNIVERSITÀ DEGLI STUDI DI MILANO-BICOCCA
    Inventors: Francesca Bartolini, Maria Elena Pero, Guido Cavaletti
  • Publication number: 20200283515
    Abstract: The present invention refers to an antibody able to recognize and bind to an epitope comprised in a sequence of human Migration Stimulating Factor (MSF), and that doesn't recognize and bind human Fibronectin 1 (hFn1) and to uses in diagnostic methods and therapy.
    Type: Application
    Filed: September 19, 2018
    Publication date: September 10, 2020
    Applicants: HUMANITAS MIRASOLE S.P.A., UNIVERSITA' DEGLI STUDI DI MILANO
    Inventors: Alberto MANTOVANI, Barbara BOTTAZZI, Ilaria LAFACE, Antonio INFORZATO, Tamara GULIC
  • Publication number: 20200164047
    Abstract: The present invention relates to at least one modulator of PP2A or at least one modulator of PP2A-like phosphatase or at least one modulator of PP2A and PP2A-like phosphatase or a combination of said modulators for use in the treatment of a disease characterized by an alteration in the DNA damage response. The present invention also relates to a method to identify a subject to be treated with a PP2A modulator comprising detecting in the genome of said patient a mutation in PP2A.
    Type: Application
    Filed: May 21, 2018
    Publication date: May 28, 2020
    Applicants: UNIVERSITÀ DEGLI STUDI DI MILANO, ISTITUTO EUROPEO DI ONCOLOGIA S.R.L., IFOM - FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE
    Inventors: Saverio MINUCCI, Mohamed ELGENDY, Riccardo CAZZOLI, Sebastiano PERI, Elisa FERRARI, Marco FOIANI
  • Publication number: 20200157418
    Abstract: Disclosed are a colloidal coating dispersion containing electrochromic polymer particles, a method for manufacturing the colloidal coating dispersion, the use of the colloidal coating dispersion for depositing at least one electrochromic layer on a substrate, and an article including a layer deposited from the colloidal coating dispersion.
    Type: Application
    Filed: November 8, 2019
    Publication date: May 21, 2020
    Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E. V., Università degli Studi di Milano - Bicocca
    Inventors: Sven MACHER, Uwe POSSET, Luca BEVERINA, Mauro SASSI, Marco SCHOTT
  • Patent number: 10644303
    Abstract: It is described a method for realizing catalytically active electrochemical electrodes with maximized surface area. In the method, InGaN is deposited epitaxially in form of a thin layer on a Silicon substrate exposing a (111) crystal fac, thus forcing the InGaN electrode material to grow exposing a catalytically active surface. The substrate is then removed, the InGaN layer is made into fragments and these are transferred onto a conductive support with one-, two- or three-dimensional structure which can be a wire, a two-dimensional conductive foil which, possibly folded, or a three-dimensional conductive fabric, sponge or cage-like structure. It is thus possible to obtain an InGaN-based electrode with increased surface area and exposing surfaces with high catalytic activity.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: May 5, 2020
    Assignee: UNIVERSITÁ DEGLI STUDI DI MILANO BICOCCA
    Inventors: Richard Noetzel, Stefano Sanguinetti
  • Publication number: 20200095387
    Abstract: The present invention regards a solid master elastomeric composition (masterbatch, MB) comprising silicate fibres with needle-shaped morphology of nanometric size, characterised by high fibre content and uniformity, a process advantageous for the preparation thereof and its use in manufacturing tyres for vehicles. Advantageously the present elastomeric composition allows minimising the drawbacks associated with the handling of the powdery fibres in the manufacturing of compounds for tyres, without altering the final performances thereof.
    Type: Application
    Filed: December 18, 2017
    Publication date: March 26, 2020
    Applicants: PIRELLI TYRE S.p.A., POLITECNICO DI MILANO, UNIVERSITA' DEGLI STUDI DI MILANO BICOCCA
    Inventors: Luciano TADIELLO, Valeria Rosaria CIPOLLETTI, Luca GIANNINI, Thomas HANEL, Maurizio GALIMBERTI, Roberto SCOTTI, Barbara DI CREDICO, Franca MORAZZONI, Massimiliano D'ARIENZO, Irene TAGLIARO
  • Patent number: 10336707
    Abstract: The present invention relates to novel heterocyclic derivatives having general formula (I) and their therapeutic use for diseases such as cancer, inflammation, pain, autoimmune diseases or neurodegenerative diseases like Alzheimer's or Parkinson's disease that can be treated by modulation of certain protein kinases. Compounds of formula (I) can be used for treatment of patients who do not respond to kinase inhibition therapy that comprises currently available medications.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: July 2, 2019
    Assignees: EUDENDRON S.R.L., UNIVERSITA' DEGLI STUDI DI MILANO
    Inventors: Mauro Angiolini, Fabio Zuccotto, Anna Bernardi, Francesco Airaghi
  • Patent number: 10143969
    Abstract: The present invention relates to novel molecules suitable to the use in the separation/removal of carbon dioxide from gaseous mixtures as liquid-phase carbon dioxide absorbers and suitable to allow the subsequent release of the absorbed carbon dioxide in form of different ionic liquids, preferentially a glycine salt with choline hexanoate, ester between glycine and hexanoic alcohol (hexyl glycinate) and glycerol ester with glycine and hexanoic acid. The present invention also relates to a method and a plant for the capture of carbon dioxide from gaseous mixtures by using an absorber for carbon dioxide in liquid phase with a heating jacket.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: December 4, 2018
    Assignee: UNIVERSITA DEGLI STUDI DI MILANO-BICOCCA
    Inventors: Maurizio Filippo Acciarri, Simona Olga Binetti, Bruno Vodopivec, Maurilio Giuseppe Meschia
  • Patent number: 10010505
    Abstract: New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: July 3, 2018
    Assignee: UNIVERSITA DEGLI STUDI DI MILANO-BICOCCA
    Inventors: Massimo Masserini, Francesca Re, Giulio Sancini, Gianluigi Forloni, Mario Salmona
  • Patent number: 9925160
    Abstract: The inventors have made the surprising discovery that when ceramide production is upregulated in the infarct and at-risk areas upon reperfusion injury in the heart, such upregulation is effected through the de novo ceramide synthesis pathway. Upon treatment of cardiac tissues subject to reperfusion injury with a specific inhibitor of the novo ceramide synthesis pathway (myriocin), the inventors have determined that the inhibition of such pathway not only reduces the inflammation of the interested area, but most surprisingly reduces infarct size, ameliorates cardiac contractility and activates cell detoxification and survival programs. There is thus provided an inhibitor of de novo ceramide synthesis pathway, particularly myriocin, for the treatment of cardiac reperfusion injury.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: March 27, 2018
    Assignees: UNIVERSITA' DEGLI STUDI DI MILANO, POLICLINICO SAN DONATO S.P.A.
    Inventors: Riccardo Ghidoni, Paola Signorelli, Luigi Anastasia
  • Patent number: 9879030
    Abstract: Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis, inflammatory diseases, pathologies involving the immune system, cardiovascular diseases, and renal diseases.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: January 30, 2018
    Assignees: UNIVERSITA′ DEGLI STUDI DI MILANO, FONDAZIONE ITALIANA SCLEROSI MULTIPLA—FISM ONLUS
    Inventors: Maria Pia Abbracchio, Mario Alberto Battaglia, Ivano Eberini, Marta Fumagalli, Chiara Parravicini, Cristina Sensi, Paola Zaratin
  • Patent number: 9822308
    Abstract: Disclosed are polymers with a complex branched structure (star- or tree-shaped) obtainable by polymerizing a bifunctional type AB monomer and/or type AA+BB monomers in the presence of: a) one or more polyamine and/or a polyacid and/or a polyalcohol and/or more generally a compound (such as POSS) having at least three functional groups such as amino, carboxylic acid or hydroxyl functions; b) one or more phosphorus containing molecules reacting with only one reactive group during the polymerization; c) optionally one or more organic acid and/or an amine and/or an alcohol having one or two functional groups.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: November 21, 2017
    Assignee: UNIVERSITA' DEGLI STUDI DI MILANO
    Inventors: Giuseppe Di Silvestro, Yuan Cuiming, Marco Ortenzi, Hermes Farina, Tommaso Lugato, Luca Basilissi
  • Patent number: 9795730
    Abstract: A blood treatment method is described that is adapted to at least partially eliminate the carbon dioxide content of the type comprising a step of drawing a blood flow. Advantageously according to the invention, the method further comprises the steps of: acidifying the blood flow with transformation of the related blood bicarbonate content into gaseous carbon dioxide; and eliminating the gaseous carbon dioxide content by means of a pressure gradient.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: October 24, 2017
    Assignee: Universitá Degli Studi di Milano-Bicocco
    Inventors: Antonio Maria Pesenti, Nicolo Antonino Patroniti
  • Publication number: 20170224898
    Abstract: The present invention relates to an extracorporeal circuit for CO2 removal from blood comprising a line for taking blood from the patient, a decarboxylation assembly and a line for returning the blood to the patient; said decarboxylation assembly comprising a first filtering unit, an oxygenator, an electrodialyzer adapted to generate an acid solution and a basic solution and means for the infusion of said acid solution upstream of said oxygenator, wherein said electrodialyzer comprises a first electrodialysis chamber and a second electrodialysis chamber, said first and second electrodialysis chambers being separated by an ionic membrane, and in that wherein said first chamber and said second chamber are respectively separated from the positive electrode, or anode, and from the negative electrode, or cathode, by means of a bipolar membrane.
    Type: Application
    Filed: July 31, 2015
    Publication date: August 10, 2017
    Applicant: UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA
    Inventors: Antonio Maria Pesenti, Alberto Zanella, Domenico Salerno, Nicolò Antonino Patroniti, Francesco Mantegazza