Abstract: Provided is a process for manufacturing magnetically tunable nano-resonators. The nano-resonators comprise nanoparticles of a crystalline magnetic material embedded into cavities of a substrate.

Abstract: A system and methods for determining a mechanical tissue characteristic (?) are provided. The system comprises a providing unit for providing a set of images of a tissue region of interest, wherein the provided set of images comprises image features indicative of one or more structural properties (?, a0, CO, PG) of the tissue region of interest and has been acquired using an imaging modality suitable for in-vivo imaging of the tissue region of interest. The system further comprises a determining unit for determining, based on the provided set of images, a mechanical tissue characteristic (?) indicative of a mechanical responsiveness of the tissue region of interest. The determining unit comprises a machine learning architecture adapted to receive the provided set of images as an input and to provide the mechanical tissue characteristic as an output.

Abstract: Medical training model having at least one blood vessel model (1) which in at least one practice region can be connected to an anatomically replicated substitute blood circulation system (2) and in which a real instrument (17) is used, further having an image recording device (3) for creating measured images of the at least one blood vessel model (1), and having an image processing device (11) which converts the recorded measured images into an imaging blood vessel representation and makes same displayable on a screen (12), wherein the image recording device (3) is designed as a photo-optical system (8) which records transmitted-light images (13) as measured images of the at least one blood vessel model (1) for simulation of medical activity, for which purpose the at least one blood vessel model (1) is replicated in a transparently produced solid-bdy block (4) for a contrast between transparent solid-body block (4) and non-transparent instrument (17).

Abstract: A method for coating one or more channels of a sample using a vapor deposition includes alternatingly supplying at least two gaseous precursor to one or more channels defined in a sample through at least one feed line that is connected to a first channel end of the one or more channels. An adjustable pressure gradient is generated and conducts the at least two gaseous precursors along a first flow direction (SR1) from the at least one feed line to a first discharge line through the one or more channels. The at least two gaseous precursor and reaction products are discharged from the one or more channels through a first discharge line that is connected to a second channel end of the one or more channels of the sample. Non-reacted precursors and reaction products are discharged through a second discharge line that is connected to the first channel end.

Abstract: A device for generating laser radiation comprises a temperature-controlled optical setup comprising an optically non-linear solid state medium arranged in a resonator and an active region. The outgoing laser radiation is generated from a pump beam introduced into the optically non-linear solid state medium. A first temperature actuator and a second temperature actuator configured to independently adjust temperature values in the active region of the optically non-linear solid state medium. The first temperature actuator is configured regulate a length of the resonator by setting a first temperature value within a first portion of the active region. The second temperature actuator is configured to match phases of wavelengths generated by the outgoing laser radiation and phases of wavelengths of the pump beam radiation by setting a second temperature value within a second portion of the active region.

Abstract: Provided is a process for manufacturing magnetically tunable nano-resonators. The nano-resonators comprise nanoparticles of a crystalline magnetic material embedded into cavities of a substrate.

Abstract: A gas feed method for a gas engine or dual-fuel engine in which combustion gas (G) is burned with combustion air (L). A gas valve (1) for the feed of combustion gas (G) into the combustion air (L) is arranged upstream of the gas engine or dual-fuel engine. The combustion gas (G) is fed in uncontrolled fashion to the gas valve (1) independently of the operating state of the gas engine or dual-fuel engine. The invention furthermore relates to a gas supply apparatus. A gas valve (1) for the feed of combustion gas (G) into the combustion air (L) is arranged in the gas feed (10) upstream of the gas engine or dual-fuel engine. Control of the gas pressure in a manner dependent on the operating state of the gas engine or dual-fuel engine is not provided upstream of the gas valve (1).

Abstract: A device for generating laser radiation comprises a temperature-controlled optical setup comprising an optically non-linear solid state medium arranged in a resonator and an active region. The outgoing laser radiation is generated from a pump beam introduced into the optically non-linear solid state medium. A first temperature actuator and a second temperature actuator configured to independently adjust temperature values in the active region of the optically non-linear solid state medium. The first temperature actuator is configured regulate a length of the resonator by setting a first temperature value within a first portion of the active region. The second temperature actuator is configured to match phases of wavelengths generated by the outgoing laser radiation and phases of wavelengths of the pump beam radiation by setting a second temperature value within a second portion of the active region.

Abstract: A biotechnological production of tryptophan and derivatives thereof, as well as a method for an enhanced microbial L-tryptophan synthesis. In one aspect the invention provides a bacterial cell being genetically modified to express anindole-3-glycerol phosphate synthase, IGPs, the IGPs being less sensitive to inhibition or even being activated by anthranilate compared to the wild type IGPs of the bacterial cell.

Abstract: A method to determine the throughput speed v of a pore, comprising the steps of feeding, by means of a driving force F, a filiform calibration element through the pore, the calibration element having a plurality of markers spaced apart by known distances and configured to produce an interaction event that transmits a signal away from the pore upon interaction with the pore, detecting a plurality of interaction events, and determining a time interval ?t between successive interaction events, and/or a frequency ? of interaction events.

Abstract: The invention proposes an In-situ Sensor (1) for being implanted within tissue of a mammal (P) comprising •an energy harvesting portion (RX), •a communication portion (TX), •a pressure sensor (SP) for measuring interstitial pressure of surrounding tissue when located within tissue, •a further sensor (SF), whereby the further sensor is selected from a group comprising pH sensor, lactate sensor, impedance sensor, radiation sensor, temperature sensor, sensor for bioelectrical potentials, •whereby said further sensor (SF), said pressure sensor (SP) as well as the communication portion (TX) are powered by the energy harvesting portion (RX), •whereby information indicative of the measurement provided by the pressure sensor (SP) and data indicative of the measurement provided by said further sensor (SF) is communicated via said communication portion (TX) towards an extracorporeal receiving entity (ECE), •whereby said communication portion (TX) and/or said pressure sensor (SP) and/or said further sensor (SF) are adap

Abstract: A use of noreugenin glycoside derivatives of formulas I, II and III as a self-tanning substance or to increase the synthesis of melanin, improve melanin transport and/or improve the distribution of melanin in suprabasal layers, preparations containing noreugenin glycoside derivatives of formulas I, II and III, and noreugenin glycoside derivatives of formulas I, II and III.

Abstract: A method for producing a lignocellulose plastic composite material, in particular a simpler and more cost-effective option for producing lignocellulose plastic composite materials. Thermoplastic particles and a mixture of water and lignocellulose-containing particles are supplied to a refiner, and the lignocellulose-containing particles are reduced to fibers in the refiner. The thermoplastic particles are supplied to the refiner in a melted or fused state, or are melted or fused in the refiner, so that the melted or fused thermoplastic particles and the lignocellulose-containing particles that are reduced to fibers form material composite particles in the refiner.

Abstract: The present invention relates to the use of noreugenin glycoside derivatives of formulas I, II and III as a self-tanning substance or to increase the synthesis of melanin, improve melanin transport and/or improve the distribution of melanin in suprabasal layers, preparations containing noreugenin glycoside derivatives of formulas I, II and III, and noreugenin glycoside derivatives of formulas I, II and III.

Abstract: The invention is directed to a novel method for measuring contraction characteristics of engineered heart tissue constructs (16) which is based on the mechanical coupling of the construct (16) to a support element (8) which comprises or is mechanically coupled to a piezoelectric element (10). An apparatus (1) for carrying out the method of the invention is also provided.

Abstract: Compounds which can be used as prodrugs, in particular nucleoside diphosphate and triphosphate prodrugs, and a method for producing these compounds. The aim is to provide improved di- and/or triphosphate prodrugs, in particular nucleotide or nucleotide analog prodrugs. This is achieved in one aspect by providing bioreversibly and asymmetrically masked di- and triphosphate compounds, in particular nucleoside diphosphate and nucleoside triphosphate compounds or the analogs thereof. The masking only occurs at the terminal phosphate, i.e. at the ?- or ?-phosphate, whereas the masking of the internal phosphate is omitted.

Abstract: The present invention relates to a lidar measurement system for the detection of the presence and/or motion of particles and/or objects in a space region remote from the lidar measurement system and comprising an interferometer arrangement, as well as to a corresponding method using such a measurement system. The interferometer arrangement comprises a continuous wave laser source (2), a photodetector arrangement (7), and optical components which are adapted to split light (23) emitted by the continuous wave laser source (2), to guide it along a first optical path constituting a measurement branch (4) and along a second optical path, which is separate from the first optical path and constitutes a reference branch (5), and to eventually have it incident in a spatially coherently superimposed manner onto the photodetector arrangement (7).

Abstract: A drive system for driving control surfaces of an aircraft includes at least one drive unit, at least one main shaft connectable to the at least one drive unit and at least two adjusting units for each control surface to be driven. Each adjusting unit includes a differential, two rotary actuators and an adjustment lever. The differential has at least one input means and two output means and is adapted to transfer torque from the at least one input means to the two output means. The input means is connectable to the main shaft, the two rotary actuators each have a rotation input means and a motion output means. The rotation input means is connectable to one of the output means of the differential each and the adjustment lever is connected to the motion output means of both rotary actuators.

Abstract: A system for in-situ spectroscopic measurements in heterogeneous catalytic reactors includes a reactor having a reactor chamber, a device for collecting a sample, and a device for collecting spectroscopic information. The device for collecting the sample includes a sampling capillary having an orifice situated inside the reactor chamber. The device for collecting spectroscopic information includes at least one optical radiation guide for guiding optical radiation onto the sample for excitation and for collecting optical radiation emitted, absorbed, reflected or scattered by the sample. The at least one optical radiation guide may be inserted into the sampling capillary, such that a tip of the at least one optical radiation guide is proximate to the orifice. A method for analyzing a reactor state including the steps of providing a reactor; collecting spectroscopic information from a sample inside the reactor chamber; and analyzing the collected spectroscopic information is also provided.

Abstract: A piezoelectric substrate having a nanopore opening that separates two reservoirs of conductive fluid may provide for sensitive biological measurements by allowing control of the size of the nanopore according to piezoelectric stimulation of the substrate. Multiple embodiments are provided of monolithic piezoelectric substrates and nanopores for this purpose as well as a control system for controlling the nanopore dimensions electrically using AC or DC waveforms.