Abstract: A coupling device between a first vehicle (A) and a second vehicle (B) includes a hinge coupling section associated with the first vehicle (A) and a drawbar section associated with the second vehicle (B). The drawbar section has an arc-shaped guide arranged horizontally in front of the second vehicle (B) to extend from the right side to the left side thereof, a slider sliding along the arc-shaped guide and a telescopic arm integral with one end of the slider and rotatably connected to the coupling section. A steering assistance mechanism provides for redundancy of the steering members (S) of the second vehicle (B). The coupling device allows the automatic guide system to control the vehicle position and trajectories without any substantial exchange of forces through the device and allows the safe stop of the convoy when there are anomalies in the operation of the automatic guide system.

Abstract: A system (1, 100) with socket (20, 120)/plug (10, 110) is described, designed to prevent access to the electrical phase contacts (32, 132) and neutral contacts (33, 133) of the socket (10, 120) when the plug (10, 110) is not inserted in the socket (20, 120), and designed to ensure a phase to phase and neutral to neutral connection, in which, inside the socket (20, 120) there is a contact holder element (30) which, following the insertion of the plug (10, 110), retracts and interacts with a system of inclined guides (25) obtained in a structural rear part (24, 124) of the socket (20, 120), causing a transversal movement of the electrical phase contacts (32, 132) and neutral contacts (33, 133), able to make a connection with the corresponding electrical phase contacts (13, 113) and neutral contacts (14, 114) present on the plug (10, 110).

Abstract: A system for monitoring and analyzing electrical operating parameters of a load (10) in a electric network (20), said system comprising a smart socket (110) arranged to be placed in series between the load (10) and the electric network (20), said smart socket (110) comprising a voltage detection module arranged to measure a voltage value in the electric network (20), as an electric potential difference between the ends of the load (10), a current detection module in the electric network (20) arranged to measure a current value adsorbed by the load (10), when the load (10) is connected to the electric network (20), a control unit connected to the voltage detection module and to the current detection module. In particular, the control unit is arranged to carry out a periodic acquisition of the voltage value in said electric network (20), obtaining a voltage trend over time and a periodic acquisition of the current value adsorbed by the load (10), obtaining a current trend over time.

Abstract: The present invention describes a bispecfic antibody composed of the variable domains (VH and VL) of two antibodies, hERG1 mAb (which binds the extracellular domain S5-P of hERG1) and of ?1 integrin mAb TS2/16 or BV7, which bind the extracellular domain of ?1 integrin. The present invention relates also to a novel anti-hERG1 molecule bearing a Cys in position 95 of the VH domain. The invention describes also their application for diagnostic and therapeutic purposes in oncology and other fields of medical sciences.

Abstract: The present invention relates to novel compounds useful as sensors for the rapid and specific determination of the FKBP12 protein, a peptidyl-prolyl cis-trans isomerase (PPlase), the levels of which in the biological fluids of a subject change if the subject is affected by pathological conditions, in particular neurodegenerative diseases, such as the Parkinson's disease and the Alzheimer's syndrome, tumour pathologies, autoimmune diseases, or if that subject is in a phase of acute rejection after organ transplantation.

Abstract: The underwater vehicle with variable configuration (1) comprises: a hull (2) consisting of at least four elongated elements (20), mutually articulated by means of joints (21), to form a first closed polygonal structure (F1), arranged on a plane; thrusters (3), associated in parallel with said elements (20) of the hull (2); actuating means (22), associated with said joints (21), provided for automatically modifying said first closed polygonal structure (F1), from an elongated shape configuration (AF1) to an expanded shape (EF1), corresponding to an elongated conformation of said hull (2), to determine a low hydrodynamic resistance and a longitudinal thrust of the thrusters (3) in the cruising of said underwater vehicle (1), and to a substantially isotropic conformation, wherein the same elements (20) of the hull (2), as well as the thrusters (3) are mutually angled, intended for the hovering of the same underwater vehicle (1), respectively.

Abstract: The present invention relates to a pharmaceutical composition useful in the prevention and treatment of atrophy or of degeneration of skeletal muscle caused by pathologies or of sarcopenia. The composition includes a combination of molecules that are modulators of the sphingosine-1-phosphate receptors S1PR and one or more pharmaceutically acceptable excipients and/or carriers.

Abstract: The present invention relates to bioactive peptides and to the cosmeceutical compositions containing them, useful for the prevention and treatment of the signs of skin aging, such as wrinkles, fine lines and loss of firmness and elasticity of the skin, thanks to their efficacy in the protection of the dermal collagen.

Abstract: A regasification apparatus includes a closed loop heat transfer fluid circulation assembly, for the storage of the cold energy extracted from fuel during its regasification, and provides: a first tank, for containing at ambient temperature the heat transfer fluid, and an insulated second tank where the latter is kept cold; a fluid/fluid heat exchanger, defining the heating means, in which the fluid, coming out of the first tank, is placed in heat transfer with the cold branch of the pipe and therefore cooled, then stored in the second tank. From the latter departs at least one insulated branch, to supply with cold fluid at least one utility present in the aforementioned vehicle, for example an air/fluid heat exchanger located downstream an intercooler of the engine. By means of a pipe, the heat transfer fluid, heated back to ambient temperature, returns to the first tank.

Abstract: Bistatic interferometric terrestrial radar comprising: a main radar unit (2) provided with ground fixing means (6) and provided with at least one transmitting unit (3) and at least one receiving unit (4); at least one amplifier transponder (5, 50) placed far away from said main unit (2), provided with ground fixing means (9) and provided with a receiving antenna (7) and a transmitting antenna (11).

Abstract: The underwater vehicle with variable configuration (1) comprises: a hull (2) consisting of at least four elongated elements (20), mutually articulated by means of joints (21), to form a first closed polygonal structure (F1), arranged on a plane; thrusters (3), associated in parallel with said elements (20) of the hull (2); actuating means (22), associated with said joints (21), provided for automatically modifying said first closed polygonal structure (F1), from an elongated shape configuration (AF1) to an expanded shape (EF1), corresponding to an elongated conformation of said hull (2), to determine a low hydrodynamic resistance and a longitudinal thrust of the thrusters (3) in the cruising of said underwater vehicle (1), and to a substantially isotropic conformation, wherein the same elements (20) of the hull (2), as well as the thrusters (3) are mutually angled, intended for the hovering of the same underwater vehicle (1), respectively.

Abstract: A process for manufacturing customized facemasks, includes: producing respective impressions of patient's forehead and chin, to record an anatomic structure thereof, using impression materials commonly utilized in dentistry for intraoral impressions; producing respective 3D digital images of a patient's forehead and chin through a 3d-scanning of the forehead and chin impressions; 3D printing of customized forehead and chin pads; detecting patient's side profile line from a side picture of patient's face; 3D printing of a midline rod modelled according to said profile line; and assembling the forehead and chin pads and said midline rod into a facemask featuring a facial frame providing retention to elastic bands connectable to an intraoral appliance, in the forehead pad a temperature sensor is inserted while a pressure sensor is embedded into the chin pad.

Abstract: An interferometric radar comprising an arm (2), which rotates with respect to an axis (z) of a plane (zx) orthogonal to an axis of rotation (y), a system of linear-polarization antennas (1), which is fixed to said arm (2) for describing complete revolutions along a circular path (c) about said axis (y) and is oriented in a direction of sight (a) parallel to the axis (y), motor-drive means (3) for driving the arm (2), a data-acquisition and processing unit (10) operatively connected to said antenna (1) for acquiring a succession of images detected by the antenna during its revolution about the axis (y) and making differential interferometric calculations for measuring at least one component of the displacement of one or more targets in the field of view, or else for measuring the digital elevation map (DEM) of the scenario in the field of view.

Abstract: An interferometric radar comprising an arm (2), which rotates with respect to an axis (z) of a plane (zx) orthogonal to an axis of rotation (y), a system of antennas (1), which are fixed to said arm (2), are able both to move along the arm and to describe complete revolutions along a circular path about said axis (y), and are oriented in a direction of sight (a) parallel to the axis (y), motor-drive means (3) for driving the arm (2) and the system of antennas along the arm, a data-acquisition and processing unit (10) operatively connected to said antenna (1) for acquiring a succession of images detected by the antenna during its revolution about the axis (y) and making differential interferometric calculations for measuring at least one component of the displacement of one or more targets in the field of view.

Abstract: A system for monitoring a building structure is described. The system comprises a laser source which emits an infrared radiation and an interferometric arrangement which divides the radiation into an object beam and a reference beam. The object beam irradiates the building structure and is scattered by it, while the reference beam interferes with the scattered object beam so as to create a hologram of the building. The system also comprises a sensor which detects a sequence of holograms and a processing unit which reconstructs the evolution in time of deformations or displacements of the building by numerically processing the sequence of holograms. The system—being based on digital holography—offers various advantages compared to known monitoring techniques, for example techniques which make use of seismometers (possibility of remote monitoring, substantial space-time continuity of the monitoring, capacity for detecting a wider range of deformations and displacements).

Abstract: A structure of drone (100) comprises a frame (110) comprising an engagement portion (110?), said engagement portion (110?) being a strip having a predetermined geometry. The structure of drone (100) also comprises a plurality of propulsion elements (120). Each propulsion element (120) is arranged, in use, to be engaged in a removable way to the engagement portion (110?) at a any point of the strip, in such a way to easily change the number and the arrangement of the propulsion elements (120) present on the engagement portion (110?).

Abstract: Low-noise current source, configured to be supplied by at least one DC main supply (Vss) and to deliver an output current (IL), the source comprising one or more current generator modules (G1, G2, . . . GN) operating in parallel each one of which is configured to deliver a respective output current (Ii), whereby the output current (IL) of the source is equal to the sum of the output currents (Ii) of said one or more current generator modules (G1, G2, . . . GN), each current generator module (G1; G2; . . . GN) comprising a regulator component (Q1), configured to deliver the output current (Ii) of the current generator module (G1; G2; . . .

Abstract: A structure of drone (100) comprises a frame (110) comprising an engagement portion (110?), said engagement portion (110?) being a strip having a predetermined geometry. The structure of drone (100) also comprises a plurality of propulsion elements (120). Each propulsion element (120) is arranged, in use, to be engaged in a removable way to the engagement portion (110?) at a any point of the strip, in such a way to easily change the number and the arrangement of the propulsion elements (120) present on the engagement portion (110?).

Abstract: The present invention refers to the field of steering dampers for motorcycles in general and in particular it refers to a steering head integrating a magnetorheological type steering damper.

Abstract: The light capsule object of the present invention is an ingestible device designed to illuminate the gastric cavity of the stomach for therapeutic purposes directed against Helicobacter pylori (H. pylori) bacteria. It comprises: a casing transparent to visible light, in turn containing punctiform light sources, preferably constituted by LEDs, positioned immediately under said casing and capable of emitting light at appropriate wavelength bands (preferably 405 nm and 630 nm); a battery, adapted to power the LED sources for approximately 20-30 minutes (the average transit time in the stomach); a switch which allows a delayed power on and allows the tablet to be still “off” when it is swallowed. The light emitted by the capsule strikes the H. pylori bacteria anchored on the gastric wall. The light radiation is preferentially absorbed by molecules of porphyrin produced by the bacterium which works as photosensitizing agent by inducing the formation of cytotoxic molecular species.